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| Resource Name | Proper Citation | Abbreviations | Resource Type |
Description |
Keywords | Resource Relationships | |||||||||||||
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BARI 2D Resource Report Resource Website 1+ mentions |
BARI 2D (RRID:SCR_001496) | BARI 2D, BARI-2D | clinical trial | A multicenter randomized clinical trial that aims to determine the best therapies for people with type 2 diabetes and moderately severe cardiovascular disease. 2368 participants were randomized at 49 sites in 6 countries. All subjects were given intensive medical therapy to control cholesterol and blood pressure and given counseling, if needed, to quit smoking and to lose weight. Beyond that, they compared whether prompt revascularization, either bypass surgery or angioplasty, e.g. stents, was more effective than medical therapy alone. At the same time, they also looked at which of two diabetes treatment strategies resulted in better outcomes����??insulin-providing versus insulin-sensitizing - that is, increasing the amount of insulin or making the insulin work better. Only patients with known type 2 diabetes and heart disease that could be treated appropriately with a revascularization OR medical therapy alone were eligible for the trial. Patients entered the study between January 2001 ����?? March 2005 and were followed for an average of five years. When a patient entered the study, physicians first decided whether that patient should receive stenting or bypass surgery. The patient then received their randomization assignment. All patients were treated in BARI 2D for both their diabetes and heart disease, as well as other risk factors that might effect those diseases, regardless of which group they were in. Diabetes-specific complications including retinopathy, nephropathy, neuropathy, and peripheral vascular disease were monitored regularly. Tests, blood samples, urine samples, and treatment cost data were obtained periodically through the trial and examined by experts at 7 central laboratories and other research partners. Experts on risk factors routinely oversaw treatments of all patients at 4 central management centers. A panel of independent experts reviewed data every six months to make sure that all patients were receiving safe care. | clinical, cholesterol, blood pressure, counseling, insulin, epidemiology, longitudinal, stenting, bypass surgery, standard-of-care study, standard-of-care, treatment, medication, outcome, medical cost, blood, urine, biomaterial supply resource |
is listed by: One Mind Biospecimen Bank Listing is listed by: NIDDK Information Network (dkNET) has parent organization: University of Pittsburgh; Pennsylvania; USA |
Type 2 diabetes, Cardiovascular disease, Heart attack, Stroke | NCRR 5M01RR000847-36 | PMID:23757426 PMID:23735723 PMID:23500245 PMID:23067918 PMID:23008442 PMID:22527794 PMID:22496082 PMID:21958742 |
Free, Freely available | nlx_152754 | SCR_001496 | Bypass Angioplasty Revascularization Investigation (BARI) 2 Diabetes, Bypass Angioplasty Revascularization Investigation 2 Diabetes | 2026-02-07 02:05:38 | 1 | ||||
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Juvenile Diabetes Research Foundation Resource Report Resource Website 50+ mentions |
Juvenile Diabetes Research Foundation (RRID:SCR_001522) | JDRF | institution | Global funder of type 1 diabetes (T1D) research that aims to progressively remove the impact of T1D from people's lives until a world without T1D is achieved. JDRF collaborates with a wide spectrum of partners and is the only organization with the scientific resources, regulatory influence, and a working plan to better treat, prevent, and eventually cure T1D. More than 80 percent of JDRF's expenditures directly support research and research-related education. In 2012 Forbes magazine named JDRF one of its five All-Star charities, citing the organization's efficiency and effectiveness. The organization awards research grants for laboratory and clinical investigations and sponsors a variety of career development and research training programs for new and established investigators. JDRF also sponsors international workshops and conferences for biomedical researchers. Individual chapters offer support groups and other activities for families affected by diabetes. | treatment, prevention, cure, research, education |
is listed by: NIDDK Information Network (dkNET) is affiliated with: Helmsley Cellular Research Hub is related to: JDRF Artificial Pancreas Project Consortium is related to: Kidney Health Initiative |
Type 1 diaberes, Diabetes | Free, Freely available | grid.429307.b, nlx_152841, Crossref funder ID: 100008871, Wikidata: Q6107958, ISNI: 0000 0004 0575 6413 | https://ror.org/00vqxjy61 | SCR_001522 | JDRF International, Juvenile Diabetes Research Foundation International | 2026-02-07 02:05:33 | 64 | |||||
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TRIGR Resource Report Resource Website 1+ mentions |
TRIGR (RRID:SCR_001550) | TRIGR | clinical trial | International, randomized, double-blinded trial to determine whether weaning to a casein hydrolysate formula during the first 6-8 months of life in place of cow milk based formula reduces the incidence of autoimmunity and type 1 diabetes in genetically susceptible newborn infants. 2160 eligible infants were randomized to test or control formulas when mothers decide to wean from exclusive breastfeeding. The participants will be monitored up to the age of 10 years for the appearance of diabetes-predictive autoantibodies and clinical type 1 diabetes. The TRIGR trial will determine whether delayed exposure to intact food proteins will reduce the chances of developing type 1 diabetes later in life. All babies in the study received the recommendation to breastfeed for at least the first six months of life. If a mother was unable to exclusively breastfeed before the baby was 8 months of age, her child was randomly assigned to one of two groups. One group of these babies received a trial formula based on extensively hydrolyzed protein; the other group received another trial formula containing a smaller amount of hydrolyzed protein. In the hydrolyzed formula, the big protein molecules have been split into very small fragments to provide a source of nutritional amino acids, but the fragments are likely too small to stimulate the immune system. The TRIGR trial will also be able to analyze whether exclusive breastfeeding per se can reduce the risk of the children to develop type 1 diabetes. | casein hydrolysate formula, newborn, hydrolyzed infant formula, genetically susceptible, insulin, cow's milk, infant, feeding, diet, intervention, genetic risk, bibliography, dietary intervention, wean, prevention, nutrition, nonhydrolyzed infant formula, breast feeding, infant formula |
is listed by: ClinicalTrials.gov is listed by: NIDDK Research Resources is listed by: NIDDK Information Network (dkNET) has parent organization: University of South Florida; Florida; USA |
Type 1 diabetes, Diabetes | NICHD HD040364; NICHD HD042444; NICHD HD051997; RTD programme Quality of Life and Management of Living Resources contract QLK1-2002-00372 |
PMID:21153533 PMID:17550422 |
Free, Freely available | nlx_152860 | http://trigr.epi.usf.edu/ http://clinicaltrials.gov/show/NCT00179777 |
SCR_001550 | TRIGR - Trial to Reduce IDDM in the Genetically at Risk, Trial to Reduce IDDM in the Genetically at Risk, TRIGR trial | 2026-02-07 02:05:32 | 1 | |||
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Grants.gov Resource Report Resource Website 10+ mentions |
Grants.gov (RRID:SCR_002661) | funding resource | A source to FIND and APPLY for federal grants. The U.S. Department of Health and Human Services is proud to be the managing partner for Grants.gov, an initiative that is having an unparalleled impact on the grant community. All discretionary grants offered by the 26 federal grant-making agencies can be found on Grants.gov. Grants.gov was established as a governmental resource named the E-Grants Initiative, part of the President's 2002 Fiscal Year Management Agenda to improve government services to the public. The concept has its origins in the Federal Financial Assistance Management Improvement Act of 1999, also known as Public Law 106-107. Public Law 106-107 has since sunset and is now known as the Grants Policy Committee (GPC). For more information on the Grants Policy Committee, click here. Today, Grants.gov is a central storehouse for information on over 1,000 grant programs and provides access to approximately $500 billion in annual awards. You may find information on *What is a Grant? *Who is Eligible for a Grant? *Program highlights and accomplishments *Grants.gov in the News (Articles, press releases, milestones and events) *Program Status (Detailed information about our relationship with partner federal agencies, financial contributions, grant opportunities, fiscal reports, planning strategies and statistics.) | grant, funding, award, database, opportunity |
is used by: NIF Data Federation is used by: Aging Portal is used by: NIDDK Information Network (dkNET) |
Free, Freely available | nif-0000-22393 | SCR_002661 | 2026-02-07 02:05:47 | 36 | |||||||||
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NCBI Resource Report Resource Website 10000+ mentions |
NCBI (RRID:SCR_006472) | NCBI | nonprofit organization | A portal to biomedical and genomic information. NCBI creates public databases, conducts research in computational biology, develops software tools for analyzing genome data, and disseminates biomedical information for the better understanding of molecular processes affecting human health and disease. | biomedical, genomic, molecular biology, health, disease, database, computational biology, bio.tools |
is used by: NIF Data Federation is listed by: NIDDK Information Network (dkNET) is listed by: bio.tools is listed by: Debian is related to: AmiGO is related to: NCBI Viral Genomes is related to: Clone DB is related to: PubReader is related to: OMIA - Online Mendelian Inheritance in Animals is related to: European Nucleotide Archive (ENA) is related to: Plant Co-expression Annotation Resource is related to: METAGENOTE is related to: Phyutility is related to: CaspBase is related to: Prokaryotic Genomes Automatic Annotation Pipeline has parent organization: National Library of Medicine is parent organization of: MedGen is parent organization of: dbSTS is parent organization of: PubMed Health is parent organization of: BLASTP is parent organization of: GQuery is parent organization of: BLASTN is parent organization of: GTEx eQTL Browser is parent organization of: BLASTX is parent organization of: Homology Maps Page is parent organization of: PEDHUNTER is parent organization of: Conserved Domain Database is parent organization of: NCBI Genome Survey Sequences Database is parent organization of: High Throughput Genomic Sequences Division is parent organization of: AceView is parent organization of: dbMHC is parent organization of: dbSNP is parent organization of: Entrez Gene is parent organization of: NCBI Genome is parent organization of: NCBI database of Genotypes and Phenotypes (dbGap) is parent organization of: GenBank is parent organization of: International HapMap Project is parent organization of: IgBLAST is parent organization of: Lowes Syndrome Mutation Database is parent organization of: HomoloGene is parent organization of: Influenza Virus Resource is parent organization of: Distant Regulatory Elements is parent organization of: e-PCR is parent organization of: MapViewer is parent organization of: Primer-BLAST is parent organization of: dbVar is parent organization of: NCBI Taxonomy is parent organization of: NCBI Protein Database is parent organization of: Gene Reference into Function is parent organization of: Protein Clusters is parent organization of: RefSeq is parent organization of: TPA is parent organization of: GENSAT at NCBI - Gene Expression Nervous System Atlas is parent organization of: COBALT: Constraint-based Multiple Alignment Tool is parent organization of: PubMed Central is parent organization of: UniLib is parent organization of: NCBI Structure is parent organization of: PubChem is parent organization of: Anopheles gambiae (African malaria mosquito) genome view is parent organization of: UniGene is parent organization of: NLM Catalog is parent organization of: Entrez GEO Profiles is parent organization of: Nucleotide database is parent organization of: NCBI BioSystems Database is parent organization of: CBLAST is parent organization of: NCBI BioProject is parent organization of: NCBI Probe is parent organization of: PubMed is parent organization of: NCBI BioSample is parent organization of: NCBI Nucleotide is parent organization of: NCBI Structure: Cn3D is parent organization of: NCBI BLAST is parent organization of: IBIS: Inferred Biomolecular Interactions Server is parent organization of: NCBI Sequence Read Archive (SRA) is parent organization of: Gene Expression Omnibus (GEO) is parent organization of: NCBI Popset is parent organization of: PIE the search is parent organization of: Genetic Testing Registry is parent organization of: NCBI Resource List is parent organization of: NCBI dbRBC is parent organization of: NCBI YouTube Channel is parent organization of: NCBI Epigenomics is parent organization of: ClinVar is parent organization of: Genome Reference Consortium is parent organization of: GeneReviews is parent organization of: Molecular Imaging and Contrast Agent Database is parent organization of: Consensus CDS is parent organization of: UniSTS is parent organization of: HIV-1 Human Protein Interaction Database is parent organization of: Assay Guidance Manual is parent organization of: Bookshelf is parent organization of: COG is parent organization of: Gene Expression Omnibus is parent organization of: Molecular Modelling DataBase is parent organization of: Organelle Genome Resources is parent organization of: SKY/M-FISH/CGH is parent organization of: dbEST is parent organization of: JournalReview.org is parent organization of: NCBI GenBank via FTP is parent organization of: PubChem Compound is parent organization of: Molecular Modeling DataBase is parent organization of: Vector Alignment Search Tool is parent organization of: PubChem BioAssay is parent organization of: NCBI Genome Workbench is parent organization of: TBLASTN is parent organization of: TBLASTX is parent organization of: Mega BLAST is parent organization of: Genetic Codes is parent organization of: HIV-1, Human Protein Interaction Database is parent organization of: PubReader is parent organization of: PubChem Substance is parent organization of: OMIA - Online Mendelian Inheritance in Animals is parent organization of: OMIM is parent organization of: 1000 Genomes: A Deep Catalog of Human Genetic Variation is parent organization of: GeneTests is parent organization of: NCBI Genome Survey Sequences Database is parent organization of: MagicBlast is parent organization of: RefSeq is parent organization of: Sequin is parent organization of: Batch Entrez is parent organization of: Entrez is parent organization of: tbl2asn is parent organization of: Whole Genome Shotgun (WGS) Project is parent organization of: Digital Differential Display (DDD) is parent organization of: BLASTClust is parent organization of: PASC is parent organization of: Open Reading Frame Finder is parent organization of: Genotyping works with: Human Mouse Disease Connection works with: A plasmid Editor works with: Database of genes related to Repeat Expansion Diseases |
Public, The community can contribute to this resource | nif-0000-00139, biotools:ncbi_resources | https://bio.tools/ncbi_resources | http://www.ncbi.nih.gov/ | SCR_006472 | National Center for Biotechnology Information, NCBI - National Center for Biotechnology Information | 2026-02-07 02:07:30 | 25407 | |||||
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Diabetes Autoantibody Standardization Program Resource Report Resource Website 10+ mentions |
Diabetes Autoantibody Standardization Program (RRID:SCR_006929) | DASP | knowledge environment | Program that develops materials and methods to improve measurements of autoantibodies that are predictive of type 1 diabetes. These are the most sensitive and meaningful measures for predicting this disease. Historically, autoantibody measures have been variable among laboratories; therefore, this program, in collaboration with the Immunology of Diabetes Society, was established. The goals of DASP are to improve laboratory methods, evaluate laboratory performance, support the development of sensitive and specific measurement technologies, and develop reference methods. Currently, 48 key laboratories from 19 countries participate in DASP. | autoantibody, quality assurance, standardization, standard, laboratory method, laboratory performance, measurement, method |
is related to: NIDDK Information Network (dkNET) has parent organization: Centers for Disease Control and Prevention |
Type 1 diabetes, Diabetes | PMID:12716742 | nlx_152868 | http://www.idsoc.org/committees/antibody/dasphome.html | SCR_006929 | Diabetes Autoantibody Standardization Program (DASP) | 2026-02-07 02:07:17 | 14 | |||||
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Symptoms of Lower Urinary Tract Dysfunction Research Network (LURN) Resource Report Resource Website |
Symptoms of Lower Urinary Tract Dysfunction Research Network (LURN) (RRID:SCR_014378) | LURN | resource | A research consortium with the long term goal of developing and testing measurement tools to describe symptoms of lower urinary tract dysfunction (LUTD) in women and men. The group plans to study targeted populations of patients with LUTD in order to expand our understanding of the causes of symptoms and common ways that symptoms change over time. The researchers will also collect biosamples from patients for current and future study of LUTD. | lower urinary tract, dysfunction, research, consortium, lutd, symptom, biosample |
is listed by: NIDDK Information Network (dkNET) is listed by: NIDDK Research Resources is listed by: Collaborating for the Advancement of Interdisciplinary Research in Benign Urology |
NIDDK 1U01DK097776 | SCR_014378 | Symptoms of Lower Urinary Tract Dysfunction Research Network | 2026-02-07 02:08:57 | 0 | ||||||||
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University of California at San Diego; California; USA Resource Report Resource Website 1+ mentions |
University of California at San Diego; California; USA (RRID:SCR_011625) | UCSD | university | The University of California, San Diego, also known as UC San Diego, is public research university located in the La Jolla neighborhood of San Diego, California, in the United States. Established in 1960, UCSD has 6 different campuses. | undergraduate, graduate, master's, doctoral, phD, institution, university |
is listed by: DataCite is affiliated with: Diabetes Research Centers is affiliated with: mysamplesize is related to: Alzheimers Disease Genetics Consortium is related to: International AMD Genetics Consortium is related to: Beta Cell Biology Consortium is related to: Clinical and Translational Science Awards Consortium is related to: Collaboratory of AIDS Researchers for Eradciation (CARE) is related to: redcap-to-nda is related to: auto-scoring is related to: FIONASITE is related to: Minimally-Processed-Image-Sharing is related to: timeline-followback is related to: little-man-task is related to: redcap-completion is related to: eprime-data-clean is related to: Fast-Track-Image-Sharing is related to: simple-t1-motion-detection is related to: tick-tock is related to: FIONA-QC-PHANTOM is related to: numerical-fitting is related to: aux-file-upload is related to: FIONA-protocol-compliance is related to: redcap-hook-framework is related to: nih-ipad-app-end-point is related to: ABCDreport is related to: delay-discounting is related to: redcap-importer is related to: pearson-central-end-point is related to: abcd-dev is related to: LungMap is related to: Lung Genome Browser is related to: Common Metabolic Disease Genome Atlas has parent organization: University of California; California; USA is parent organization of: MPScope is parent organization of: University of California at San Diego Cognitive Science Graduate Student Fellowship Opportunities is parent organization of: BindingDB is parent organization of: OntoMorph Tab is parent organization of: Digital Asset Management System is parent organization of: CARTA is parent organization of: MitoProteome is parent organization of: 3DVC is parent organization of: UCSD Center for NMR Spectroscopy and Imaging of Proteins is parent organization of: Kawasaki Disease Dataset is parent organization of: San Diego Supercomputer Center is parent organization of: UCSD Cognitive Science: The Future of Cognitive Science is parent organization of: Shiley-Marcos Alzheimer's Disease Research Center is parent organization of: University of California at San Diego Department of Psychiatry is parent organization of: Swartz Center for Computational Neuroscience is parent organization of: Cell Centered Database is parent organization of: National Center for Microscopy and Imaging Research is parent organization of: National Biomedical Computation Resource is parent organization of: Center for Research in Biological Systems is parent organization of: Community Cyberinfrastructure for Advanced Marine Microbial Ecology Research and Analysis is parent organization of: La Jolla Interdisciplinary Neurosciences Center is parent organization of: Neuroscience Information Framework is parent organization of: Brainscape is parent organization of: SciCrunch is parent organization of: MAGI is parent organization of: iDASH is parent organization of: UCSD-TV is parent organization of: Network Data Exchange (NDEx) is parent organization of: bioCADDIE is parent organization of: UC San Diego Biorepository is parent organization of: National Resource for Network Biology is parent organization of: Lifesharing Tissue Services is parent organization of: Velvet-SC is parent organization of: Transporter Classification Database is parent organization of: Arnaud Delormes Programs Overview is parent organization of: IntegromeDB is parent organization of: SciVee is parent organization of: EEG / ERP Data Set is parent organization of: UCSD Experimental Neuropath Laboratory is parent organization of: FORCE11 is parent organization of: HIV Neurobehavioral Research Center is parent organization of: cd-hit-454 is parent organization of: OneLab is parent organization of: Systems Transcriptional Activity Reconstruction is parent organization of: HeadIT is parent organization of: BiGG Database is parent organization of: Research Accelerator is parent organization of: Rosalind is parent organization of: Divvy is parent organization of: AbsCN-seq is parent organization of: LIPID Metabolites And Pathways Strategy is parent organization of: UCSD-Nature Signaling Gateway Molecule Pages is parent organization of: Whole Brain Catalog is parent organization of: CCHDO is parent organization of: CD-HIT is parent organization of: SDSC Biology Workbench is parent organization of: Swami: The Next Generation Biology Workbench is parent organization of: Booly: A Resource for Biological Data Integration is parent organization of: Molecule pages in neurobiology is parent organization of: University of California, San Diego, Department of Pharmacology is parent organization of: Combinatorial Extension (CE) is parent organization of: Homophila is parent organization of: University of California San Diego Department of Neurosciences is parent organization of: Archives of General Psychiatry is parent organization of: Cal-IT2: Immersive Visualization Laboratory is parent organization of: Institute for Neural Computation is parent organization of: CHARTER - CNS HIV Antiretroviral Therapy Effects Research is parent organization of: Multimodal Imaging Laboratory is parent organization of: Center for Computational Mass Spectrometry is parent organization of: Joint Center for Structural Genomics is parent organization of: Alzheimer's Disease Cooperative Study is parent organization of: Ion Simulator Interface is parent organization of: BioLit is parent organization of: Conical: The Computational Neuroscience Class Library is parent organization of: Digital Fish Library is parent organization of: UCSD Center for AIDS Research Molecular Biology Core is parent organization of: Grid Enabled Molecular Science Through Online Networked Environments is parent organization of: Finite Element Toolkit is parent organization of: Disease Phenotype Ontology is parent organization of: PTSD-TBI INTRuST is parent organization of: Kawasaki Disease Dataset2 is parent organization of: Pediatric Imaging Neurocognition and Genetics is parent organization of: Cerebral Blood Flow Database and Analysis Pipeline is parent organization of: CBFBIRN is parent organization of: UCSD Digital Collections is parent organization of: SIGnAL Salk Institute Genomic Analysis Laboratory is parent organization of: Datamonkey is parent organization of: EULER-SR is parent organization of: Omics Discovery Index is parent organization of: Dangerous Ideas is parent organization of: University of California San Diego School of Medicine; California; USA is parent organization of: ICA (Independent Component Analysis) for dummies is parent organization of: SpikeNET is parent organization of: HOMER is parent organization of: Hammer is parent organization of: CAMERA is parent organization of: RAMMCAP is parent organization of: WebMGA is parent organization of: Research Collaboratory for Structural Bioinformatics Protein Data Bank (RCSB PDB) is parent organization of: Alliance for Cellular Signaling Molecule Pages Database is parent organization of: Unys is parent organization of: Mass spectrometry Interactive Virtual Environment (MassIVE) is parent organization of: UCSD Human Milk Biorepository is parent organization of: Reprever is parent organization of: NIDDK Information Network (dkNET) is parent organization of: Cytoscape is parent organization of: BrainInfo is parent organization of: Kepler is parent organization of: TOPSAN is parent organization of: Virmid is parent organization of: neurospy is parent organization of: LAMHDI: The Initiative to Link Animal Models to Human DIsease is parent organization of: HED Tags is parent organization of: Molecular Dynamics Workflow (BioKepler) is parent organization of: Drug Design Data Resource is parent organization of: RepeatScout is parent organization of: GenomeSpace is parent organization of: geocoding is parent organization of: enroll is parent organization of: findMotif.pl is parent organization of: Diabetes Epigenome Atlas is parent organization of: Diabetes Epigenome Atlas is parent organization of: Lab Streaming Layer is parent organization of: Brainome portal is parent organization of: SPARC Anatomy Working Group is parent organization of: Open Science Chain is parent organization of: GNPS is parent organization of: COVID-19 Data Discovery from Clinical Records is parent organization of: FAIR Data Informatics Laboratory is parent organization of: Smart-seq2 Single Nucleus Multi Sample Pipeline is parent organization of: Cocaine Biobank is parent organization of: C-GORD is parent organization of: University of California at San Diego Electron Microscopy Core Facility is parent organization of: University of California at San Diego Institute for Genomic Medicine Genomics Center Core Facilitiy is parent organization of: Flye is parent organization of: Open Data Commons for Spinal Cord Injury is parent organization of: MetGENE is parent organization of: ReDU is parent organization of: Immune Epitope Database and Analysis Resource (IEDB) is parent organization of: Cell Image Library (CIL) is parent organization of: Open Data Commons for Traumatic Brain Injury |
ISNI 0000 0001 2107 4242, Crossref Funder ID 100007911, nlx_71933, Wikidata Q622664, GRID grid.266100.3, SCR_016626 | https://api.datacite.org/dois?prefix=10.6075 https://ror.org/0168r3w48 |
SCR_011625 | University of California San Diego, University of California San Diego; California; USA, UC San Diego, UC San Diego; California; USA | 2026-02-07 02:08:21 | 4 | |||||||
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Functional Dyspepsia Treatment Trial Resource Report Resource Website |
Functional Dyspepsia Treatment Trial (RRID:SCR_006691) | FDTT | resource, clinical trial | Multi-center, randomized, placebo-controlled trial evaluating the tricyclic antidepressant, amitriptyline and the selective serotonin reuptake inhibitor (SSRI), escitalopram to placebo in patients with functional dyspepsia. The purpose of this study is to determine whether amitriptyline and escitalopram are more efficacious than placebo in relief of the symptoms of functional dyspepsia, adjusting for psychological and psychiatric co-morbidities. | antidepressant, amitriptyline, selective serotonin reuptake inhibitor, escitalopram, placebo |
is listed by: NIDDK Information Network (dkNET) is listed by: NIDDK Research Resources has parent organization: ClinicalTrials.gov |
Functional dyspepsia | NIDDK | PMID:22343090 | nlx_152830 | SCR_006691 | Antidepressant Therapy for Functional Dyspepsia, Functional Dyspepsia Treatment Trial (FDTT) | 2026-02-07 02:15:11 | 0 | |||||
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Maryland Genetics of Interstitial Cystitis Resource Report Resource Website |
Maryland Genetics of Interstitial Cystitis (RRID:SCR_006992) | MaGIC | resource, clinical trial | Clinical study that investigated several hundred families with two or more blood relatives with interstitial cystitis in order to understand the molecular genetic basis of this condition. The study sought to find changes in genes that are found far more commonly in family members who have interstitial cystitis than in those who do not have the disease. Identifying these genes should lead to a better understanding of the cause of interstitial cystitis. This is a national study which is conducted by telephone and mail, and in which participants could participate entirely from their home. | male, female, adolescent, adult human, genetics, risk factor, family history, bladder, pain, observational |
is related to: NIDDK Information Network (dkNET) has parent organization: ClinicalTrials.gov has parent organization: University of Maryland School of Medicine; Maryland; USA |
Interstitial cystitis | NIDDK | nlx_152843 | http://icresearch.umaryland.edu/magic.aspx | SCR_006992 | Maryland Genetics of Interstitial Cystitis (MaGIC) | 2026-02-07 02:15:03 | 0 | |||||
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High-dose Ursodiol Therapy of Primary Sclerosing Cholangitis Resource Report Resource Website |
High-dose Ursodiol Therapy of Primary Sclerosing Cholangitis (RRID:SCR_006772) | HUSC | resource, clinical trial | Multi-center, placebo-controlled trial of ursodiol in primary sclerosing cholangitis (PSC). A total of 150 patients with previously untreated PSC without cirrhosis were randomly assigned to receive high doses of ursodiol (20-25 mg/kg/day) or placebo for two years. Patients underwent medical evaluation, endoscopic retrograde cholangiography, and liver biopsy before randomization and again at two-year intervals. The endpoints of therapy were progression of hepatic fibrosis, liver decompensation, liver transplantation, or death. The treatment phase of the study was stopped for futility in June 2008; however, patients continue to be followed. Ongoing mechanistic studies are underway. | treatment, placebo, ursodeoxycholic acid, intervention, randomized, adult human, male, female |
is listed by: NIDDK Information Network (dkNET) is listed by: NIDDK Research Resources has parent organization: ClinicalTrials.gov |
Primary Sclerosing Cholangitis | NIDDK | PMID:19585548 | nlx_152836 | SCR_006772 | Trial of High-dose Urso in Primary Sclerosing Cholangitis, High-dose Ursodiol Therapy of Primary Sclerosing Cholangitis (HUSC), Multicentered Randomized Trial of High-dose Urso in Primary Sclerosing Cholangitis | 2026-02-07 02:15:11 | 0 | |||||
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Efficacy and Mechanisms of Glutamine Dipeptide in the Surgical Intensive Care Unit Resource Report Resource Website |
Efficacy and Mechanisms of Glutamine Dipeptide in the Surgical Intensive Care Unit (RRID:SCR_006806) | GLND | resource, clinical trial | Multi-center, double-blind, placebo-controlled, intent-to-treat Phase III trial, designed to determine the effect of parenteral glutamine (GLN) dipeptide on important clinical outcomes in patients requiring surgical intensive care unit (SICU) care and parenteral nutrition (PN) after cardiac, vascular, or intestinal surgery. Patients who required PN and SICU care will receive either standard glutamine (GLN)-free PN (STD-PN) or isocaloric, isonitrogenous alanyl-glutamine dipeptide (AG)-PN until enteral feedings are established. The study will determine whether AG-PN decreases hospital mortality, nosocomial infection and other important indices of morbidity and will obtain mechanistically relevant observational data in the subjects on whether AG-PN a) increases serial blood concentrations of glutathione (GSH), heat shock proteins (HSP)-70 and -27, and glutamine; b) decreases the serum presence of the bacterial products flagellin and lipopolysaccharide (LPS) and the adaptive immune response to these mediators; and c) improves key indices of innate and adaptive immunity. | parenteral nutrition, glutamine, glutamine dipeptide, clinical, outcome, adult human, mortality, nosocomial infection, immune cell function, hospital morbidity, morbidity, intensive care |
is listed by: ClinicalTrials.gov is listed by: NIDDK Information Network (dkNET) is listed by: NIDDK Research Resources has parent organization: Emory University; Georgia; USA |
Critical illness | NIDDK U01DK069322 | PMID:18596310 | nlx_152823 | http://www.sph.emory.edu/GLND | SCR_006806 | Phase III Study on the Efficacy of Glutamine Dipeptide-Supplemented Parenteral Nutrition in Surgical ICU Patients, Efficacy and Mechanisms of GLN Dipeptide in the SICU, Efficacy and Mechanisms of GLN Dipeptide in the SICU (GLND), GLND trial | 2026-02-07 02:15:11 | 0 | ||||
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Frequent Hemodialysis Network Nocturnal Trial Resource Report Resource Website |
Frequent Hemodialysis Network Nocturnal Trial (RRID:SCR_007014) | FHN Nocturnal Trial | resource, clinical trial | Randomized controlled clinical trial where subjects will be randomized to conventional hemodialysis delivered three days per week home arm or to the six times per week nocturnal home hemodialysis arm which will follow any dialysis prescription provided their prescribed standardized Kt/V is at least 4.0 and treatment time is at least 6.0 hours, six times per week. Subjects were recruited from dialysis units associated with designated Clinical Centers in the U.S. and Canada and followed for 12 months. Primary Outcome Measures: * composite of 12 month mortality and the change over 12 months in left ventricular mass by cine-MRI, * a composite of 12 month mortality and the change over 12 months in the SF-36 RAND physical health composite Secondary Outcome Measures: * cardiovascular structure/funct (change in LV mass over 12 mos), health-related QoL/phys funct (change over 12 mos in PHC), * depression / dis burden (change over 12 mos in Beck Depression Inv.), nutrition (change over 12 mos in serum albumin, cognitive funct (change over 12 mos in TrailMaking Test B), mineral metabolism (change over 12 mos in aveg pre-dialysis serum phosphorus), * clin events (rate of non-access hospital or death * hypertension, anemia | hemodialysis, home, adult human, kidney, kidney disease |
is listed by: ClinicalTrials.gov is related to: Frequent Hemodialysis Network Daily Trial is related to: NIDDK Information Network (dkNET) has parent organization: NIDDK - National Institute of Diabetes and Digestive and Kidney Diseases |
End Stage Renal Disease, Hemodialysis | NIDDK | PMID:21775973 PMID:17164834 PMID:17699439 |
nlx_152829 | SCR_007014 | Frequent Hemodialysis Network (FHN) Nocturnal Trial, Frequent Hemodialysis Network: Nocturnal Trial | 2026-02-07 02:15:04 | 0 | |||||
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Program to Reduce Incontinence by Diet and Exercise Resource Report Resource Website 5000+ mentions |
Program to Reduce Incontinence by Diet and Exercise (RRID:SCR_009018) | PRIDE | resource, clinical trial | Randomized controlled trial being conducted at two clinical centers in the United States to learn more about the effects of weight loss on urinary incontinence. About 330 overweight women aged 30 or older will participate and will be followed for 18 months. Efficacy of weight reduction as a treatment for urinary incontinence will be examined at 6 months following the intensive weight control program, and the sustained impact of the intervention will be examined at 18 months. To increase the maintenance of weight reduction and facilitate evaluation of the enduring impact of weight loss on urinary incontinence, they propose to study a motivation-based weight maintenance program. At the end of the intensive weight control program, women randomized to the weight loss program will be randomized to either a 12-month skill-based maintenance intervention or to a motivation-based maintenance intervention. The maintenance interventions maximize the potential for sustained weight loss and will allow them to determine if long-term weight reduction will produce continued improvement in urinary incontinence. | female, adult human, weight reduction, intervention, behavior, diet, exercise, motivation, weight maintenance |
is listed by: ClinicalTrials.gov is related to: NIDDK Information Network (dkNET) has parent organization: University of California at San Francisco; California; USA |
Urinary incontinence, Obesity, Weight loss, Overweight, Aging | NIDDK UO1 DK67860 | PMID:20664387 PMID:20680012 PMID:19179316 PMID:20643425 |
nlx_152847 | SCR_009018 | PRIDE (Program to Reduce Incontinence by Diet and Exercise) | 2026-02-07 02:15:10 | 6544 | |||||
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ACCORD Resource Report Resource Website 100+ mentions |
ACCORD (RRID:SCR_009015) | ACCORD | resource, clinical trial | Study testing whether strict glucose control lowers the risk of heart disease and stroke in adults with type 2 diabetes. In addition the study is exploring: 1) Whether in the context of good glycemic control the use of different lowering lipid drugs will further improve these outcomes and 2) If strict control of blood pressure will also have additional beneficial effects on reducing cardiovascular disease. The design was a randomized, multicenter, double 2 X 2 factorial trial in 10,251 patients with type 2 diabetes mellitus. It was designed to test the effects on major CVD events of intensive glycemia control, of fibrate treatment to increase HDL-cholesterol and lower triglycerides (in the context of good LDL-C and glycemia control), and of intensive blood pressure control (in the context of good glycemia control), each compared to an appropriate control. All 10,251 participants were in an overarching glycemia trial. In addition, one 2 X 2 trial addressed the lipid question in 5,518 of the participants and the other 2 X 2 trial addressed the blood pressure question in 4,733 of the participants. The glycemia trial was terminated early due to higher mortality in the intensive compared with the standard glycemia treatment strategies. The results were published in June 2008 (N Eng J Med 2008;358:2545-59). Study-delivered treatment for all ACCORD participants was stopped on June 30, 2009, and the participants were assisted as needed in transferring their care to a personal physician. The lipid and blood pressure results (as well as the microvascular outcomes and eye substudy results) were published in 2010. All participants are continuing to be followed in a non-treatment observational study. | middle adult human, late adult human, glycemic control, lowering lipid drug, blood pressure, lipid, clinical |
is related to: NIDDK Information Network (dkNET) has parent organization: National Heart Lung and Blood Institute |
Cardiovascular disease, Stroke, Type 2 diabetes, Diabetes, Aging | NHLBI ; NIDDK ; NEI ; CDC ; NIA |
PMID:23490598 PMID:23253271 PMID:23238658 PMID:22723583 PMID:22646230 |
nlx_152746 | SCR_009015 | Action to Control Cardiovascular Disease Risk in Diabetes | 2026-02-07 02:15:13 | 172 | |||||
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Zebrafish Gene Collection Resource Report Resource Website 1+ mentions |
Zebrafish Gene Collection (RRID:SCR_007054) | ZGC | biomaterial supply resource, material resource | Part of zebrafish genome project. ZGC project to produce cDNA libraries, clones and sequences to provide complete set of full-length (open reading frame) sequences and cDNA clones of expressed genes for zebrafish. All ZGC sequences are deposited in GenBank and clones can be purchased from distributors of IMAGE consortium. With conclusion of ZGC project in September 2008, GenBank records of ZGC sequences will be frozen, without further updates. Since definition of what constitutes full-length coding region for some of genes and transcripts for which we have ZGC clones will likely change in future, users planning to order ZGC clones will need to monitor for these changes. Users can make use of genome browsers and gene-specific databases, such as UCSC Genome browser, NCBI's Map Viewer, and Entrez Gene, to view relevant regions of genome (browsers) or gene-related information (Entrez Gene). | cdna library, clone, sequence, full-length open reading frame, cdna clone, frozen, fish, gene, genetic, genome, genomic |
is listed by: One Mind Biospecimen Bank Listing is related to: One Mind Biospecimen Bank Listing is related to: NIDDK Information Network (dkNET) is related to: Mammalian Gene Collection is related to: GenBank is related to: ATCC has parent organization: National Cancer Institute |
NIH Blueprint for Neuroscience Research | Free, Freely available | nif-0000-00567 | https://genecollections.nci.nih.gov/ZGC/ | SCR_007054 | Zebrafish Gene Collection | 2026-02-07 02:14:15 | 1 | |||||
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International Mouse Phenotyping Consortium (IMPC) Resource Report Resource Website 1000+ mentions |
International Mouse Phenotyping Consortium (IMPC) (RRID:SCR_006158) | IKMC, IMPC | biomaterial supply resource, material resource | Center that produces knockout mice and carries out high-throughput phenotyping of each line in order to determine function of every gene in mouse genome. These mice will be preserved in repositories and made available to scientific community representing valuable resource for basic scientific research as well as generating new models for human diseases. | phenotype, phenotyping, gene, knockout mouse, knockout, genome, function, gene function, mouse model, mutation, embryonic stem cell, genotype, disease, anatomy, procedure, image, experimental protocol, annotation, genotype-phenotype, FASEB list |
uses: LAMA is used by: NIF Data Federation is recommended by: NIDDK Information Network (dkNET) lists: VPV is listed by: One Mind Biospecimen Bank Listing is listed by: NIDDK Information Network (dkNET) is affiliated with: iMITS is related to: HARP is related to: KOMP2 is related to: Knockout Mouse Project Repository at JAX is related to: TheBehaviourForum.org is parent organization of: Impress provides: Knockout Mouse Project Repository works with: GenTaR |
NIH Office of the Director UM1 OD023222 | PMID:27626380 PMID:24652767 PMID:24197666 PMID:25127743 PMID:25343444 PMID:24642684 PMID:21677750 PMID:22968824 PMID:22940749 PMID:22991088 PMID:25992600 PMID:22566555 PMID:23519032 PMID:22211970 PMID:24194600 PMID:26147094 PMID:24634472 PMID:24932005 PMID:25093073 PMID:24046361 PMID:24033988 PMID:23315689 PMID:22926223 PMID:21185382 PMID:21737429 PMID:19933761 PMID:19689210 PMID:17905814 PMID:17218247 PMID:16933996 PMID:16254554 PMID:15908916 PMID:15340423 PMID:15340424 PMID:28650954 PMID:28650483 PMID:29026089 PMID:29348434 PMID:29352221 PMID:29396915 PMID:29626206 PMID:22566555 |
Free, Freely available | nlx_151660 | https://www.mousephenotype.org/data/documentation/data-access | SCR_006158 | KOMP, KOMP-CSD, KOMP-Regeneron, IMPC - International Mouse Phenotyping Consortium, International Mouse Phenotyping Consortium, IMPC, International Mouse Phenotyping Consortium (IMPC), EUCOMM, IKMC | 2026-02-07 02:14:12 | 2430 | ||||
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Chronic Renal Insufficiency Cohort Study Resource Report Resource Website 1+ mentions |
Chronic Renal Insufficiency Cohort Study (RRID:SCR_009016) | CRIC Study, CRIC | biomaterial supply resource, material resource | A prospective observational national cohort study poised to make fundamental insights into the epidemiology, management, and outcomes of chronic kidney disease (CKD) in adults with intended long-term follow up. The major goals of the CRIC Study are to answer two important questions: * Why does kidney disease get worse in some people, but not in others? * Why do persons with kidney disease commonly experience heart disease and stroke? The CRIC Scientific and Data Coordinating Center at Penn receives data and provides ongoing support for a number of Ancillary Studies approved by the CRIC Cohort utilizing both data collected about CRIC study participants as well as their biological samples. The CRIC Study has enrolled over 3900 men and women with CKD from 13 recruitment sites throughout the country. Following this group of individuals over the past 10 years has contributed to the knowledge of kidney disease, its treatment, and preventing its complications. The NIDDKwill be extending the study for an additional 5 years, through 2018. An extensive set of study data is collected from CRIC Study participants. With varying frequency, data are collected in the domains of medical history, physical measures, psychometrics and behaviors, biomarkers, genomics/metabolomics, as well as renal, cardiovascular and other outcomes. Measurements include creatinine clearance and iothalamate measured glomerular filtration rate. Cardiovascular measures include blood pressure, ECG, ABI, ECHO, and EBCT. Clinical CV outcomes include MI, ischemic heart disease-related death, acute coronary syndromes, congestive heart failure, cerebrovascular disease, peripheral vascular disease, and composite outcomes. The CRIC Study has delivered in excess of 150,000 bio-samples and a dataset characterizing all 3939 CRIC participants at the time of study entry to the NIDDKnational repository. The CRIC Study will also be delivering a dataset to NCBI''''s Database for Genotypes and Phenotypes. | clinical, epidemiology, management, outcome, adult human, medical history, physical measure, psychometrics, behavior, renal, biomarker, genomics, gwas, kidney, data sharing, bibliography, observational cohort study, male, female, cardiovascular, heart, kidney, risk factor, metabolomics |
is listed by: One Mind Biospecimen Bank Listing is listed by: NIDDK Information Network (dkNET) is listed by: NIDDK Research Resources is listed by: Diabetes Research Centers is related to: NCBI database of Genotypes and Phenotypes (dbGap) is related to: NIDDK Central Repository is related to: AASK Clinical Trial and Cohort Study has parent organization: University of Pennsylvania Perelman School of Medicine; Pennsylvania; USA |
Chronic kidney disease, Cardiovascular disease | NIDDK | Proposals to carry out ancillary studies are welcome | nlx_152758 | SCR_009016 | Chronic Renal Insufficiency Cohort (CRIC) Study | 2026-02-07 02:14:35 | 2 | |||||
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University of Chicago Digestive Diseases Research Core Center Tissue Engineering and Cell Models Core Resource Report Resource Website 1+ mentions |
University of Chicago Digestive Diseases Research Core Center Tissue Engineering and Cell Models Core (RRID:SCR_015604) | TECM | biomaterial supply resource, material resource | Core that provides services such as a repository for intestinal cell lines, Tissue Engineering Models, experimental materials, and supplies for digestive disease research. | TECM, tissue engineering, cell models |
is listed by: NIDDK Information Network (dkNET) has parent organization: University of Chicago Digestive Diseases Research Core Center is organization facet of: University of Chicago Digestive Diseases Research Core Center |
digestive disease | NIDDK P30 DK042086 | Available to the research community | SCR_015604 | 2026-02-07 02:14:43 | 1 | |||||||
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Irritable Bowel Syndrome Outcome Study Resource Report Resource Website |
Irritable Bowel Syndrome Outcome Study (RRID:SCR_001504) | IBSOS | resource, clinical trial | Multi-center placebo-controlled randomized clinical trial to assess the short-term and long-term efficacy of cognitive behavior therapy (CBT) for irritable bowel syndrome (IBS) using two treatment delivery systems: self administered CBT and therapist administered CBT. Long term project goals are to develop an effective self-administered behavioral treatment program that can enhance the quality of patient care, improve clinical outcomes, and decrease the economic and personal costs of one of the most prevalent and intractable gastrointestinal disorders. | gastrointestinal disorder, cognitive behavior therapy, self-management, self-administered |
is listed by: NIDDK Information Network (dkNET) has parent organization: University at Buffalo; New York; USA |
Irritable bowel syndrome | NIDDK 5U01DK077738-07 | PMID:22846389 | Free | nlx_152839 | SCR_001504 | 2026-02-07 02:14:56 | 0 |
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