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http://www.scienceexchange.com/facilities/bionet-academic-health-center-ahc

BioNet serves the University of Minnesota''''s Academic Health Center (AHC) as a centralized biorepository and bioregistry for patient consent and for the collection, processing, and distribution of de-identified tissue samples, blood and body fluids, purified DNA and specimen-matched clinical data for research. BioNet is becoming a major translational research resource linking clinical medicine, pathology, and basic and applied research to facilitate high quality and cost-conscious clinical and translational research. BioNet leverages the strengths of the Cancer Center''''s Tissue Procurement Facility (TPF), which has become part of BioNet. BioNet currently provides: * an optimized consenting process, * collection of tissue, blood, and fluid samples, * computerized specimen tracking systems that link -specimens to clinical data and other databases, * addition of core pathologist-supported facilities for histologic interpretation, immunohistochemistry, laser capture microdissection, and slide digitalization.

Proper citation: University of Minnesota Bionet - Academic Health Center (RRID:SCR_012469) Copy   

•   Source: SciCrunch Registry

http://www.scienceexchange.com/facilities/monoclonal-antibody-core-facility-dfci-harvard

THIS RESOURCE IS NO LONGER IN SERVICE. Documented on May 16,2024. Monoclonal Antibody Core at Dana-Farber Cancer Institute produces novel monoclonal antibodies for use in basic research, drug discovery, and clinical applications including diagnosis, surrogate markers for disease status, response to therapy, and drug toxicity. Services include cloning and scale-up of immunization antigens to purification of the resulting antibodies. Researchers can choose to have all phases of antibody production conducted by the core or perform particular steps in their own lab. Services -Consultation on design of antigens and screening strategies -Production of vectors and protein with appropriate tags for immunization and screening -Immunization of animals including mice, rats and hamsters -Generation of monoclonal antibodies -Customized screening by WB, ELISA, flow cytometry -Antibody isotyping, titering, and specificity evaluation -Small, medium, and large-scale antibody production -Purification of antibodies -Antibody productivity assessment -Cryopreservation and recovery of hybridomas from liquid nitrogen -Hybridoma banking -Adaptation of hybridomas to serum-free media -Mycoplasma testing for hybridomas and other cell lines

Proper citation: DFCI Monoclonal Antibody Core Facility (RRID:SCR_012504) Copy   

•   Source: SciCrunch Registry

https://www.k-inbre.org/pages/k-inbre_about_bio-core.html

The K-INBRE Bioinformatics Core collaborates with Kansas researchers to perform research on cell and developmental biology. Core aims to serve the needs of investigators engaged in computationally intensive biomedical research, and to promote education in bioinformatics to students and researchers across the state of Kansas.

Proper citation: Kansas State University - INBRE Bioinformatics Core Facility (RRID:SCR_012596) Copy   

•   Source: SciCrunch Registry

http://www.scienceexchange.com/facilities/epigenome-center-data-production-facility-usc

Core conducts genome-scale epigenetic and genetic data production and analysis, technology development, and epigenomic and population-based genomic research.

Proper citation: University of Southern California Epigenome Center Data Production Facility (RRID:SCR_012476) Copy   

•   Source: SciCrunch Registry

http://www.scienceexchange.com/facilities/applied-genomics-technology-center-agtc-wayne-state

The Applied Genomics Technology Center (AGTC), a part of Wayne State University School of Medicine''''s Department of Obstetrics and Gynecology, is an exceptional research support core facility located on campus. Housed on the ground floor of the C.S. Mott Center for Human Growth and Development, the AGTC is a state-of-the-art, fee-for-service genomics center that provides a wide range of genomic technologies to the medical research community. In addition to instrumentation, AGTC personnel are available to work with investigators to optimize experiments to meet their scientific goals.

Proper citation: WSU Applied Genomics Technology Center (RRID:SCR_012519) Copy   

•   Source: SciCrunch Registry

http://www.scienceexchange.com/facilities/machine-shop-umass

The UMMS Machine Shop is a support service dedicated to assisting research in a technical/mechanical manner. Although all types of basic laboratory apparatus are manufactured and repaired on a regular basis, we specialize in design and fabrication of equipment that is not commercially available. No job too big or too small, too simple or too complex. Our staff is experienced and knowledgeable in working with all plastics and composites, all metals and alloys. We have over 35 years combined of experience in biomedical design and machining experience and are always available to discuss projects either at the shop or at your location. The Machine Shop is located at the Shrewsbury Campus. Pick-up and delivery of jobs can be arranged at your convenience.

Proper citation: UMass Medical School Machine Shop (RRID:SCR_012633) Copy   

•   Source: SciCrunch Registry

http://www.scienceexchange.com/facilities/plateforme-snp-transcriptome-and-epigenomics

THIS RESOURCE IS NO LONGER IN SERVICE, documented on September 02, 2014. Core facility that plays an active role in the Loire Valley Region''s officially-accredited fields of competitive excellence: plant sciences, medicine and pharmacy, child-oriented research.

Proper citation: University of Angers Plateforme SNP Transcriptome and Epigenomics (RRID:SCR_012478) Copy   

•   Source: SciCrunch Registry

https://www.crr.columbia.edu/raraf

RARAF is dedicated to providing user-friendly radiation sources and bio-labs for research in biology, radiation biology, and radiation physics.

Proper citation: Columbia University Radiological Research Accelerator Core Facility (RRID:SCR_012639) Copy   

•   Source: SciCrunch Registry

http://www.scienceexchange.com/facilities/transgenic-mouse-shared-resource-columbia

THIS RESOURCE IS NO LONGER IN SERVICE. Documented on April 22, 2024. Core facility that specializes in the generation and analysis of genetically modified mice, including transgenic and knockout animals, is an essential technology for biomedical research. Our services include: Production of transgenic mice by pronuclear DNA microinjection and embryo transfer. Production of chimeric mice by blastocyst injection of genetically modified ES cells and embryo transfer, which is part of the procedure of producing knockout or knockin mice. Gene targeting, which involves the electroporation of a targeting vector into pluripotent mouse embryonic stem (ES) cells and the selection of gene-targeted clones. Education of investigators and advice on vector and experimental design for experiments using transgenic and knockout mice. Bioimaging: The Animal Imaging Service provides investigators the opportunity for non-invasive detection, localization, and longitudinal monitoring of primary and metastatic cancer cells in vivo, in allograft, zenograft, transgenic and knock-out mouse models. The IVIS Spectrum (Caliper Life Sciences, Hopkinton MA) uses optical imaging technology to detect bioluminescent and fluorescent reporters across the blue to near infrared wavelength region. DNA samples and ES cell lines are injected in the order in which the signed service request forms are received. Currently, the average time from receipt of the service request to injection is approximately 2 weeks. For ES Cell electroporation and expansion, success in gene targeting cannot be guaranteed due to inherent variability in the frequency of targeting different loci, and the possibility of mistakes or mutations in the targeting vector.

Proper citation: Columbia Transgenic Mouse Shared Resource (RRID:SCR_012640) Copy   

•   Source: SciCrunch Registry

http://genepool.bio.ed.ac.uk/

The GenePool is a next-generation genomics and bioinformatics facility based within the School of Biological Sciences, The University of Edinburgh. Which offers collaborative access to DNA sequencing, genotyping and bioinformatics capabilities, using ABI 3730 Sanger, Illumina and Roche 454 technology platforms.

Proper citation: University of Edinburgh GenePool Next Generation Sequencing and Bioinformatics (RRID:SCR_012485) Copy   

•   Source: SciCrunch Registry

http://www.scienceexchange.com/facilities/electron-microscopy-core-laboratory-upenn

The Electron Microscopy Resource Laboratory (EMRL ) at Penn is a research facility dedicated to ultrastructure analysis of biological samples by electron microscopy (EM). We offer high quality EM imaging services at low cost. With a team of experienced professional staff and state-of-the-art sample preparation and imaging equipment, the EMRL offers users a full spectrum of both transmission EM and scanning EM services.

Proper citation: Penn Electron Microscopy Core Laboratory (RRID:SCR_012642) Copy   

•   Source: SciCrunch Registry

https://pcrlab.vetmed.ucdavis.edu/

Real-time PCR Research and Diagnostics Core Facility accepts research projects from both academic and private sector. The Core Facility can accommodate projects involving laser microdissection, RNA and DNA extractions through semi-automated nucleic acid extractions systems, cDNA synthesis and complete Real-time PCR analysis using a laser 7900 HTA FAST platform.

Proper citation: University of California at Davis Real Time PCR Research and Diagnostics Core Facility (RRID:SCR_012641) Copy   

•   Source: SciCrunch Registry

http://www.scienceexchange.com/facilities/protein-structure-core-facility

THIS RESOURCE IS NO LONGER IN SERVICE. Documented on April 25,2024. Protein Structure Core Facility operates in the department of Biochemistry and Molecular Biology, on the UNMC campus. The facility performs protein sequencing, amino acid analysis and peptide mapping on a fee-for-service basis. It is located on the first floor of the Durham Research Center

Proper citation: UNMC Protein Structure Core Facility (RRID:SCR_012609) Copy   

•   Source: SciCrunch Registry

http://www.scienceexchange.com/facilities/babraham-commercialisation-services-ltd

Babraham Institute Enterprise Limited (BIE) is the wholly-owned trading arm of the Babraham Institute. The Babraham Institute undertakes innovative life-sciences research to discover the molecular mechanisms that underlie normal cellular processes and functions, with the aim of improving lifelong wellbeing and healthy ageing.

Proper citation: Babraham Institute Enterprise Limited (RRID:SCR_012566) Copy   

•   Source: SciCrunch Registry

http://www.scienceexchange.com/facilities/clinical-pharmacology-analytical-services-cpas

The Clinical Pharmacology Analytical Services laboratory (CPAS) resides in the Department of Experimental and Clinical Pharmacology (ECP) in the University of Minnesota College of Pharmacy. CPAS offers quantification services of drug concentrations in biological samples. The CLIA-certified lab and its team of researchers and clinicians the resources to measure drug concentrations in blood and tissue samples of human and animal origin, including animals as patients and animals serving as research models. The lab which opened in October 2003 uses state-of-the-art equipment to facilitate analysis of drugs, xenobiotics, endogenous compounds and biological samples. Capabilities of the core lab include LC-MS/MS, LC-MS, GC-MS, HPLC-UV and HPLC-FLD. Additional, UV and fluorescent plate readers and liquid scintillation counters are available for conducting ELISA, RIA and other assays in a 96-well plate format. Because of its flexible structure, customers can purchase only the services they need, including assay consultation, assay development and validation, conduct of assays and application. Lab services are made available to researchers from within and outside the University of Minnesota community.

Proper citation: University of Minnesota Clinical Pharmacology Analytical Services (RRID:SCR_012603) Copy   

•   Source: SciCrunch Registry

https://www.montclair.edu/mmrl/

Interdisciplinary research, teaching and service facility equipped with scanning and transmission electron microscopes, an atomic force microscope, and the ancillary instruments. Provides microscopic imaging, X-ray analysis, and specimen preparation services for biological, pharmaceutical, and materials scientific research. The MMRL consist of four individual microscope rooms, the Histology laboratory, and sample preparation and chemical storage areas.Graduate- and upper-undergraduate-level training is offered in the operation of electron microscopes, sample preparation, and thick/thin sectioning. Currently, MMRL houses transmission electron, scanning electron microscopes, and atomic force microscope. The microscopes available for use include: - Hitachi H-7500 transmission electron microscope - Hitachi S-3400N variable pressure scanning electron microscope with x-ray analysis and digital imaging - Hitachi S-2460N scanning electron microscope with x-ray analysis In addition, the following items are also available for MMRL users: - Three Leica 2030 rotary paraffin microtome - Two LKB ultramicrotomes - A LKB 7800 glass knife maker - Leica Reichert Ultratrim - Denton critical point dryer - Denton sputter coaters (Desk II and Desk IV) - Denton Vacuum evaporators (DV-502A) - Liquid nitrogen dewars (various sizes) - A Leica stereo dissecting microscope - A Tissue-TeK VIP Tissue Processor - A Tissue-TeK II Embedding Center

Proper citation: Montclair University Microscopy and Microanalysis Research Laboratory Core Facility (RRID:SCR_012453) Copy   

•   Source: SciCrunch Registry

http://www.scienceexchange.com/facilities/immunodetection-and-imaging

Delivering high quality immunohistochemical and immunofluorescent staining on cells and tissue sections, specialising in multi immunoflourescent colocalisation staining technologies. Equipped with three Vision Biosystems Bond staining robots Mike offers high throughput or custom antibody optimisation services. Time consuming multi colocalisation including same species primaries, are automated saving time and money. A large range of imaging platforms including three confocals, widefield, stereology, image analysis, digital photograpy and PALM laser capture microscopy are available. A full range of secondary antibodies and detection systems are available for purchase in ul quantities. There are currently 1900 antibodies recorded on our database.

Proper citation: University of Edinburgh Immunodetection and Imaging (RRID:SCR_012573) Copy   

•   Source: SciCrunch Registry

http://www.scienceexchange.com/facilities/biomolecular-interaction-centre

The Biomolecular Interaction Centre (BIC) is a multi-disciplinary centre dedicated to the study of molecular interactions critical to biological function. Understanding biomolecular interactions is central to a range of fundamental sciences, new treatments for disease, and a wide range of highly functional products. The Institute includes University of Canterbury researchers from the Colleges of Science and Engineering, as well as Education and Arts and partners with several New Zealand CRIs and Universities. The Centre was founded in 2007 after being awarded funding from the Innovation and Development Fund from the Tertiary Education Commission (TEC). The primary investment of $1.85 million was used to purchase of a suite of state-of-the-art equipment that was supplied by Bio-Rad Laboratories. BIC has recently received a multi-million dollar investment from the University of Canterbury to become one of two new premier research institutes on campus. BIC researchers seek to understand the molecular interactions vital to biology and harness them in a wide range of applications. BIC has a number of Principal, Partner, Associate and Affliated Investigators, together with Post Doctoral Fellows, Postgraduate students and technicians from the University of Canterbury, as well as, other national and international institutions. Many these investigators directly support the research themes of the Centre while others have related research projects that benefit from BIC support.

Proper citation: University of Canterbury Biomolecular Interaction Centre (RRID:SCR_012618) Copy   

•   Source: SciCrunch Registry

http://www.scienceexchange.com/facilities/pathology-core-facility

THIS RESOURCE IS NO LONGER IN SERVICE. Documented on May 2,2024. Core Pathology is a self funding, CPA accredited department and therefore is a fee-for-service facility providing Histopathology services to members of Queen Mary University and other academic institutes, as well as providing a diagnostic service to the private sector. Our remit is to advise, support or carry out work for research groups.

Proper citation: QMUL BICM Pathology Core Facility (RRID:SCR_012587) Copy   

•   Source: SciCrunch Registry

http://www.scienceexchange.com/facilities/small-animal-imaging-core-umass

THIS RESOURCE IS NO LONGER IN SERVICE. Documented on April 23,2024. UMMS Small Animal Imaging Core was established in early 2008 to serve the UMMS and extramural research community by providing state-of-the-art small animal imaging.

Proper citation: UMass Medical School Small Animal Imaging Core (RRID:SCR_012620) Copy   

•   Source: SciCrunch Registry