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SciCrunch Registry is a curated repository of scientific resources, with a focus on biomedical resources, including tools, databases, and core facilities - visit SciCrunch to register your resource.

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Resource Name Proper Citation Abbreviations Resource Type Description Keywords Resource Relationships Related Condition Funding Defining Citation Availability Website Status Alternate IDs Alternate URLs Old URLs Parent Organization Resource ID Synonyms Record Last Update Mentions Count
Rolexa
 
Resource Report
Resource Website
1+ mentions
Rolexa (RRID:SCR_013017) Rolexa software resource Software that provides probabilistic base calling, quality checks and diagnostic plots for Solexa sequencing data. is listed by: OMICtools
has parent organization: Bioconductor
OMICS_01156 SCR_013017 2026-02-14 02:02:26 1
cn.mops
 
Resource Report
Resource Website
10+ mentions
cn.mops (RRID:SCR_013036) cn.mops software resource A data processing pipeline for copy number variations and aberrations (CNVs and CNAs) from next generation sequencing (NGS) data. bio.tools is listed by: OMICtools
is listed by: Debian
is listed by: bio.tools
has parent organization: Bioconductor
biotools:cn.mops, OMICS_00335 https://bio.tools/cn.mops SCR_013036 Copy Number estimation by a Mixture Of PoissonS 2026-02-14 02:02:20 10
HiTC
 
Resource Report
Resource Website
50+ mentions
HiTC (RRID:SCR_013175) HiTC software resource Software package to explore high-throughput ''C'' data such as 5C or Hi-C. is listed by: OMICtools
has parent organization: Bioconductor
OMICS_00524 SCR_013175 2026-02-14 02:02:27 83
Repitools
 
Resource Report
Resource Website
10+ mentions
Repitools (RRID:SCR_013242) Repitools software resource Software tools for the analysis of enrichment-based epigenomic data. is listed by: OMICtools
has parent organization: Bioconductor
OMICS_00619 SCR_013242 2026-02-14 02:02:50 21
CancerMutationAnalysis
 
Resource Report
Resource Website
CancerMutationAnalysis (RRID:SCR_013181) CancerMutationAnalysis software resource Software package that implements gene and gene-set level analysis methods for somatic mutation studies of cancer. is listed by: OMICtools
has parent organization: Bioconductor
Cancer OMICS_00141 SCR_013181 2026-02-14 02:02:50 0
SRAdb
 
Resource Report
Resource Website
10+ mentions
SRAdb (RRID:SCR_006524) SRAdb software resource Software package to make access to the compilation of metadata from NCBI SRA and tools associated with submission, study, sample, experiment and run much more feasible. This is accomplished by parsing all the NCBI SRA metadata into a SQLite database that can be stored and queried locally. Fulltext search in the package make querying metadata very flexible and powerful. fastq and sra files can be downloaded for doing alignment locally. Beside ftp protocol, the SRAdb has funcitons supporting fastp protocol (ascp from Aspera Connect) for faster downloading large data files over long distance. The SQLite database is updated regularly as new data is added to SRA and can be downloaded at will for the most up-to-date metadata. bio.tools is listed by: OMICtools
is listed by: Debian
is listed by: bio.tools
is related to: NCBI Sequence Read Archive (SRA)
has parent organization: Bioconductor
PMID:23323543 Artistic License, v2 biotools:sradb, OMICS_01032 https://bio.tools/sradb SCR_006524 SRAdb - A compilation of metadata from NCBI SRA and tools 2026-02-14 02:01:18 18
MethylSeekR
 
Resource Report
Resource Website
50+ mentions
MethylSeekR (RRID:SCR_006513) MethylSeekR software resource A software package for the discovery of regulatory regions from Bis-seq data. is listed by: OMICtools
has parent organization: Bioconductor
GNU General Public License, v2 or greater OMICS_00607 SCR_006513 MethylSeekR - Segmentation of Bis-seq data 2026-02-14 02:01:18 54
casper
 
Resource Report
Resource Website
100+ mentions
casper (RRID:SCR_006613) casper software resource Software to infer alternative splicing from paired-end RNA-seq data. The model is based on counting paths across exons, rather than pairwise exon connections, and estimates the fragment size and start distributions non-parametrically, which improves estimation precision. bio.tools is listed by: OMICtools
is listed by: Debian
is listed by: bio.tools
has parent organization: Bioconductor
GNU General Public License, v2 or greater biotools:casper, OMICS_01270 https://bio.tools/casper SCR_006613 casper - Characterization of Alternative Splicing based on Paired-End Reads, Characterization of Alternative Splicing based on Paired-End Reads 2026-02-14 02:01:19 149
ChIPXpress
 
Resource Report
Resource Website
1+ mentions
ChIPXpress (RRID:SCR_006653) ChIPXpress software resource A R package designed to improve ChIP-seq and ChIP-chip target gene ranking using publicly available gene expression data. It takes as input predicted transcription factor (TF) bound genes from ChIPx data and uses a corresponding database of gene expression profiles downloaded from NCBI GEO to rank the TF bound targets in order of which gene is most likely to be functional TF target. gene expression, chip-seq, chip-chip, transcription factor, target gene, gene, gene expression profile is listed by: OMICtools
is related to: Gene Expression Omnibus
has parent organization: Bioconductor
GNU General Public License, v2 or greater OMICS_00516 SCR_006653 ChIPXpress: enhanced transcription factor target gene identification from ChIP-seq and ChIP-chip data using publicly available gene expression profiles 2026-02-14 02:01:13 2
EDASeq
 
Resource Report
Resource Website
100+ mentions
EDASeq (RRID:SCR_006751) EDASeq software resource Software for numerical and graphical summaries of RNA-Seq read data. Within-lane normalization procedures to adjust for GC-content effect (or other gene-level effects) on read counts: loess robust local regression, global-scaling, and full-quantile normalization (Risso et al., 2011). Between-lane normalization procedures to adjust for distributional differences between lanes (e.g., sequencing depth): global-scaling and full-quantile normalization (Bullard et al., 2010)., THIS RESOURCE IS NO LONGER IN SERVICE. Documented on September 16,2025. data analysis, normalization, rna-seq is listed by: OMICtools
has parent organization: Bioconductor
has parent organization: National Cancer Institute
THIS RESOURCE IS NO LONGER IN SERVICE OMICS_01231 SCR_006751 EDASeq: Exploratory Data Analysis and Normalization for RNA-Seq data 2026-02-14 02:01:23 254
ggtree
 
Resource Report
Resource Website
50+ mentions
ggtree (RRID:SCR_018560) data visualization software, software resource, data processing software, software application Software R package for visualization and annotation of phylogenetic trees with their covariates and other tree like structures with their annotation data. Can import evolutionary data from different tree file formats and analysis programs as well as other associated data from experiments so that various sources and types of data can be displayed on tree for comparison and further analyses. Phylogenetic tree visualization, phylogenetic tree annotation, data, bio.tools is listed by: CRAN
is listed by: Bioconductor
is listed by: Debian
is listed by: bio.tools
Seed Funding Programme for Basic Research DOI:10.1111/2041-210X.12628 Free, Available for download, Freely available biotools:ggtree https://bio.tools/ggtree SCR_018560 2026-02-14 02:03:39 54
minet
 
Resource Report
Resource Website
minet (RRID:SCR_018661) network analysis software, data processing software, data analysis software, software toolkit, software application, software resource Open source software R package for inferring large transcriptional networks using mutual information. Implements algorithms for inferring networks such as gene networks from microarray data. Inferring transcriptional network, mutual information, gene network, microarray data, gene, statistical dependencies model, gene to gene interaciton, statistical quantification, bio.tools is listed by: Debian
is listed by: bio.tools
is related to: Bioconductor
has parent organization: Free University of Brussels; Brussels; Belgium
Communaute Francaise de Belgique PMID:18959772 Free, Available for download, Freely available biotools:minet http://minet.meyerp.com/
https://bio.tools/minet
SCR_018661 Mutual Information NETworks 2026-02-14 02:03:37 0
scTHI
 
Resource Report
Resource Website
1+ mentions
scTHI (RRID:SCR_018918) scTHI data analysis software, software resource, data processing software, software application Software R package to identify active pairs of ligand receptors from single cells in order to study,among others, tumor host interactions. Contains set of signatures to classify cells from tumor microenvironment. Ligand receptor, active pair, active pair ligand receptor, single cell, tumor interaction, tumor microenvironment, cells clasification is listed by: Bioconductor Free, Available for download, Freely available SCR_018918 2026-02-14 02:03:27 1
variancePartition
 
Resource Report
Resource Website
50+ mentions
variancePartition (RRID:SCR_019204) data processing software, data analysis software, data analytics software, software application, software resource Software R package to quantify and interpret divers of variation in multilevel gene expression experiments.Provides statistical and visualization framework for studying drivers of variation in RNA-seq datasets in many types of high throughput genomic assays including RNA-seq gene-, exon- and isoform-level quantification, splicing efficiency, protein quantification, metabolite quantification, metagenomic assays, methylation arrays and epigenomic sequencing assays. Repeated measures, variation in gene expression, RNA-seq datasets, high throughput genomic assays, splicing efficiency, protein quantification, metabolite quantification, metagenomic assays, methylation arrays, epigenomic sequencing assays, bio.tools is listed by: Bioconductor
is listed by: bio.tools
is listed by: Debian
is related to: CRAN
NHLBI U01 HL107388;
Icahn School of Medicine at Mount Sinai
PMID:27884101 Free, Available for download, Freely available biotools:variancepartition https://bio.tools/variancepartition SCR_019204 2026-02-14 02:03:29 52
SynergyFinder
 
Resource Report
Resource Website
500+ mentions
SynergyFinder (RRID:SCR_019318) data visualization software, data processing software, software toolkit, software application, software resource Software R package as efficient implementations for all popular synergy scoring models for drug combinations, including HSA, Loewe, Bliss and ZIP and visualization of synergy scores as either two dimensional or three dimensional interaction surface over dose matrix. Used to calculate and visualize synergy scores for drug combinations. Synergy scores, drug combinations, popular synergy scoring models, dimensional interaction surface, dose matrix, bio.tools is listed by: Bioconductor
is listed by: bio.tools
is listed by: Debian
is related to: SynergyFinder web application
DOI:10.1007/978-1-4939-7493-1_17 Free, Available for download, Freely available biotools:synergyfinder https://bio.tools/synergyfinder SCR_019318 synergyfinder 2026-02-14 02:03:31 510
CiteFuse
 
Resource Report
Resource Website
1+ mentions
CiteFuse (RRID:SCR_019321) data analysis software, software resource, data processing software, software application Software R package consisting of suite of tools for doublet detection, modality integration, clustering, differential RNA and protein expression analysis, antibody-derived tag evaluation, ligand-receptor interaction analysis and interactive web-based visualization of CITE-seq data. Data pre processing, modality integration, clustering, differential RNA, ADT, expression analysis, ADT evaluation, ligand receptor interaction analysis, CITE-seq data, cellular indexing of transcriptomes and epitopes by sequencing, bio.tools is listed by: Bioconductor
is listed by: bio.tools
is listed by: Debian
has parent organization: University of Sydney; Sydney; Australia
PMID:32353146 Free, Available for download, Freely available biotools:citefuse https://bioconductor.org/packages/CiteFuse/
https://github.com/SydneyBioX/CiteFuse/
http://shiny.maths.usyd.edu.au/CiteFuse/
https://bio.tools/CiteFuse
SCR_019321 Cellular Indexing of Transcriptomes and Epitopes Fuse, Cellular indexing of transcriptomes and epitopes Fuse 2026-02-14 02:03:48 2
GAGE
 
Resource Report
Resource Website
50+ mentions
GAGE (RRID:SCR_017067) data analysis software, software resource, data processing software, software application Software R package for gene set enrichment or pathway analysis. Applicable independent of microarray or RNAseq data attributes including sample sizes, experimental designs, assay platforms, and other types of heterogeneity. Pipeline routines of multiple GAGE analyses in batch, comparison between parallel analyses, and combined analysis of heterogeneous data from different sources and studies. gene, set, enrichment, pathway, batch, comparison, parallel, analysis, heterogeneous, data is listed by: Bioconductor
is related to: R Project for Statistical Computing
Free, Available for download, Freely available SCR_017067 Generally Applicable Gene-set Enrichment for pathway analysis, gage, Generally Applicable Gene-set Enrichment, GSEA 2026-02-14 02:03:08 50
affydata
 
Resource Report
Resource Website
affydata (RRID:SCR_016976) AffyData data processing software, data or information resource, data analysis software, software application, software resource Software R package for analysis of Affymetrix Data. Contains samples data files of a large size. analysis, Affymetrix, data, large, dataset, oligonucleotide, array is listed by: Bioconductor
is related to: affy
is related to: R Project for Statistical Computing
Free, Available for download, Freely available SCR_016976 affydata, Affymetrix Data, Affymetrix Data for Demonstration Purpose 2026-02-14 02:03:07 0
CATALYST
 
Resource Report
Resource Website
100+ mentions
CATALYST (RRID:SCR_017127) data processing software, data analysis software, software toolkit, software application, software resource Software R package to provide pipeline for preprocessing of cytometry data, including normalization using bead standards, single cell deconvolution, and bead based compensation. preprocessing, cytometry, data, normalization, bead, standard, single, cell, deconvulsion, compensation, bio.tools uses: CATALYSTLite
is listed by: Bioconductor
is listed by: bio.tools
is listed by: Debian
Swiss National Science Foundation ;
SNSF Assistant Professorship grant ;
PhosphonetPPM and MetastasiX SystemsX grant ;
NIDDK UC4 DK108132;
European Research Council ;
Roche Postdoctoral Fellowship
PMID:29605184 Free, Available for download, Freely available biotools:catalyst https://github.com/HelenaLC/CATALYST
https://bio.tools/catalyst
SCR_017127 Cytometry dATa anALYSis Tools 2026-02-14 02:03:15 223
fgsea
 
Resource Report
Resource Website
100+ mentions
fgsea (RRID:SCR_020938) data analysis software, software resource, data processing software, software application Software R package for fast preranked gene set enrichment analysis. Allows to make more permutations and get more fine grained p-values, which allows to use accurate stantard approaches to multiple hypothesis correction. Gene set enrichment analysis, preranked gene set, multiple hypothesis correction, bio.tools is listed by: Bioconductor
is listed by: bio.tools
is listed by: Debian
DOI:10.1101/060012 Free, Available for download, Freely available biotools:fgsea https://github.com/ctlab/fgsea/
https://bio.tools/fgsea
SCR_020938 fast gene set enrichment analysis, Fast Gene Set Enrichment Analysis, FGSEA 2026-02-14 02:04:35 185

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