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http://www.scienceexchange.com/facilities/tubingen-ageing-and-tumour-immunology-group-tati

THIS RESOURCE IS NO LONGER IN SERVICE. Documented on April 19,2024. TATI is located at the Center for Medical Research (Zentrum fuer Medizinische Forschung, ZMF) within the University of Tuebingen Clinical School (Universitaetsklinikum Tuebingen) . We are engaged in immune monitoring (cancer immunotherapy, vaccination of elderly, Alzheimer) using 14-colour flow cytometry.

Proper citation: Tubingen Ageing and Tumour Immunology Group (RRID:SCR_012627) Copy   

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http://www.scienceexchange.com/facilities/babraham-commercialisation-services-ltd

Babraham Institute Enterprise Limited (BIE) is the wholly-owned trading arm of the Babraham Institute. The Babraham Institute undertakes innovative life-sciences research to discover the molecular mechanisms that underlie normal cellular processes and functions, with the aim of improving lifelong wellbeing and healthy ageing.

Proper citation: Babraham Institute Enterprise Limited (RRID:SCR_012566) Copy   

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http://thelongevityfoundation.org/

Funding resource that supports research into A-T (Ataxia Telangiectasia) and other debilitating, degenerative diseases plaguing human kind, including cancer and neuro-degeneration associated with auto-immunity and aging. Researchers share their findings and collaborate with each other. The research must lead to practical, near-term treatments and cures to receive funds. The researchers have found treatments and cures that are the first of their kind in the world. Over $850,000 in direct research grants have been made. These grants have leveraged over $9 million in research resources contributed by partner institutions. We pay the research institutions for direct costs only. We pay no administrative, indirect, or overhead costs.

Proper citation: Longevity Foundation (RRID:SCR_006338) Copy   

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http://www.alzprotect.com/en/

Commercial organization that develops drug candidates in the field of neurodegenerative diseases and particularly Alzheimer's. Their main objective is the development of a drug against Alzheimer's disease from molecules patented by Inserm and the University of Lille II.

Proper citation: AlzProtect (RRID:SCR_000492) Copy   

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http://www.salk.edu/

The Salk Institute conducts research within three major areas of study: Molecular Biology and Genetics; Neurosciences; and Plant Biology. Six key areas represent strategic research priorities: Chemistry and Proteomics; Stem Cell Biology; Cell Biology; Regulatory Biology; Metabolic Research; and Computational and Theoretical Biology.

Proper citation: Salk Institute for Biological Studies (RRID:SCR_000752) Copy   

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http://www.stanford.edu/~yesavage/ROC.html

Software program designed to help the average clinician/researcher with a PC to evaluate clinical databases and discover the characteristics of patients, including genetics that best predict a binary outcome. That outcome may be any binary outcome such as: * Whether or not the patient has a certain disorder (medical test evaluation) * Whether or not the patient is likely to develop a certain disorder (risk factor evaluation) * Whether or not the patient is likely to respond to a certain treatment (evaluation of treatment moderators) When the predictors considered are themselves all binary (e.g., male/female; inpatient/outpatient; symptoms present/absent), the program identifies the optimal predictor. When one or more of the predictors are ordinal (e.g., age, severity of symptoms) it identifies the optimal cutpoint for each or the ordinal predictors, as well as the overall optimal predictor.

Proper citation: Signal Detection Software for Receiver Operator Characteristics (RRID:SCR_008752) Copy   

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http://www.alzheimer-hellas.gr/english.php

A non-profit organization whose aim is to offer advice concerning the care of Alzheimer''''s disease patients, information and services for the people affected and their families. Also, to offer mutual help to the family members of the patients in order to reduce the social, economic and emotional cost deriving from the long care of people suffering from dementia. Lastly, the association attempts to publicize the social needs of the population affected and to inform the public in order to be acquainted with the problem. The mission of the Greek Association of Alzheimer''''s Disease is * the early diagnosis of dementia by scientists * the promotion of research * education and training for all the stakeholders * the development of Care Units for patients with Alzheimer''''s Disease * the provision of useful information and advise (24 hour help-line) on dementia problems (caring, legal or financial issues) * the presentation of lectures by health professionals and informal carers, covering all aspects of Alzheimer Disease * and the development of professional seminars during the whole year.

Proper citation: Greek Association of Alzheimers Disease and Related Disorders (RRID:SCR_003938) Copy   

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http://www.alz.org/

A non profit organization dedicated to providing support for patients and families with Alzheimer's disease, to educating the public about the disease, to funding a wide range of Alzheimer's disease related research and to finding ways to treat and eventually to prevent Alzheimer's disease. Resources include: the Alzheimer's Association Green-Field Library, a research grants program, and the Journal of the Alzheimer's Association.

Proper citation: Alzheimers Association (RRID:SCR_007398) Copy   

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http://www.progeriaresearch.org/index.html

The mission of The Progeria Research Foundation is to discover treatments and the cure for Progeria, and its aging related disorders. Progeria is a rare and fatal genetic disease characterized by an appearance of accelerated aging in children. Without the discovery of new treatments, all children with Progeria will die of heart disease at an average age of 13 years. The Progeria Research Foundation (PRF) was founded in 1999 in response to the complete lack of progress being made to help children with Progeria. We have filled a void, taking these children out of the background where they had been for over 100 years and putting them and Progeria at the forefront of scientific efforts. In just 11.5 years, we have achieved extraordinary progress towards our mission: the Progeria gene discovery in 2003, first-ever clinical drug trials initiated in 2007, extensive global awareness of the disease and PRF''s work, and discovery of critical biological links between Progeria, heart disease and aging we all experience.

Proper citation: Progeria Research Foundation (RRID:SCR_012786) Copy   

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http://www.ohioalzcenter.org/

The University Memory and Aging Center (formerly known as University Alzheimer Center) is a partnership of Case Western Reserve University and University Hospitals of Cleveland promoting the best possible care for persons with memory problems, and assisting their families, through an integrated program of clinical services, research, and education. Our staff includes a wide range of professionals dedicating their time and efforts to understand and work for the betterment of those affected by any disorder which affects cognitive abilities. We include Neuroscientists, Neurologists, Psychologists, Sociologists, Social Workers, Nurses, Clinical trials coordinators, Research Assistants, Data Managers and Administrative staff. We work with researchers in Cleveland, throughout the US and around the globe.

Proper citation: University Memory and Aging Center (RRID:SCR_010611) Copy   

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http://www.fli-leibniz.de/

The Leibniz Institute for Aging Research - Fritz Lipmann Institute (FLI) is the first national research institute in Germany that deals with biomedical research into human aging. Aging is a multifactorial process that is influenced by the environment and genetic factors.

Proper citation: Fritz Lipmann Institute; Jena; Germany (RRID:SCR_011250) Copy   

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http://www.mst.edu/

Founded in 1870 as one of the first technological schools west of the Mississippi, Missouri S&T is one of the nation''s top technological research universities. Missouri S&T produced the engineers, scientists and innovators who helped drive the Industrial Revolution and launch the Space Age. Today, our graduates are poised to lead the new global, green economy.

Proper citation: Missouri University of Science and Technology; Missouri; USA (RRID:SCR_011396) Copy   

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http://www.stanford.edu/~yesavage/GDS.html

A basic screening measure for depression in older adults. They have a FREE iPhone APP and a FREE ANDROID APP that allows you to do the 15-item GDS on your phone and automatically calculate the results. They provide no interpretation of results, but patients with scores higher than 5 should be interviewed carefully. These apps are also available through the Android Marketplace or iTunes stores on your phones. Note: This page is under continuous development but they will try to keep translations of the scale available. Anyone with their own translation can submit it and they''ll post it.

Proper citation: Geriatric Depression Scale (RRID:SCR_008739) Copy   

•   Source: SciCrunch Registry

http://psychiatry.stanford.edu/alzheimer/files/gpkt.pdf

50 question test devised by Javaid Sheikh, M.D., and Jerome A. Yesavage, M.D., of the Department of Psychiatry and Behavioral Sciences at Stanford University School of Medicine, to test one''s knowledge of certain aspects of geriatric psychiatry, including five broad areas: psychodynamics and psychotherapy, cognitive assessment, psychosocial and developmental aspects, psychopharmacology, and clinical syndromes.

Proper citation: Geriatric Psychiatry Knowledge Test (RRID:SCR_009029) Copy   

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http://www.brain.northwestern.edu/research/for-researchers/index.html

Tissue bank for collecting, cataloging and storing postmortem brain tissue samples from subjects with and without neurological disorders. Specimens are available for research on cognitive impairment, Alzheimer's, dementia and other disorders along with clinical data such as demographic information, health and family history and neuropsychological test scores. The bank provides services to distribute postmortem brain tissue and other samples to investigators for use in research that will provide qualitative and quantitative diagnostic information to physicians, families, and researchers.

Proper citation: Northwestern CNADC Tissue Bank / Neuropathology Core (RRID:SCR_013178) Copy   

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http://www.alzresearch.org/index.cfm

A Alzheimer's Disease Research Center (ADRC) whose goal is to conduct basic and clinical research aimed at understanding Alzheimer's disease. The Center enrolls a variety of individuals for clinical trials, evaluation and follow-up, including: normal control subjects, individuals with mild memory problems, and patients diagnosed with Alzheimer's Disease or related dementias. Researchers can request data and specimens obtained from ADRC subjects. These include blood or DNA, brain specimens, and cross-sectional or longitudinal clinical and cognitive data, all from ADRC subjects.

Proper citation: Johns Hopkins Alzheimer's Disease Research Center (RRID:SCR_008757) Copy   

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http://www.bri.ucla.edu/research/resources

Brain bank resources which include postmortem human frozen brain tissue and matched cerebrospinal fluid (CSF) and blood available for scientists to search for etiopathogeneses of human disease. The National Neurological Research Specimen Bank and the Multiple Sclerosis Human Neurospecimen Bank maintains a collection of quick frozen and formalin fixed postmortem human brain tissue and frozen cerebrospinal fluid from patients with neurological diseases, including Alzheimer's Disease, amyotrophic lateral sclerosis, depressive disorder/suicide, and epilepsy, among others. Diagnoses are documented by clinical medical records and gross/microscopic neuropathology. The Neuropathology Laboratory at the UCLA Medical Center maintains a bank of frozen, formalin and paraformaldehyde-fixed and paraffin-embedded postmortem human brain tissues and frozen cerebrospinal fluid (CSF) from patients who die with Alzheimer's disease and other dementing and degenerative illnesses, as well as control materials removed in a similar fashion from patients who are neurologically normal.

Proper citation: Brain Research Institute Biobank Resources (RRID:SCR_008756) Copy   

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http://mayoresearch.mayo.edu/mayo/research/dickson_lab/

A brain bank and laboratory focused on memory and motor disorders. Brains are sent to the laboratory for diagnosis and research for the State of Florida Alzheimer Disease Initiative and for the Society for Progressive Supranuclear Palsy. As part of this brain banking function, fixed and frozen brain samples are obtained at autopsy and sent to the laboratory for diagnostic evaluation and for various types of research studies. The major types of analyses performed on the brain samples include neuro-histology, immunohistochemistry, confocal microscopy, electron microscopy and image analysis, as well as immunoassays. The latter are based upon Western blotting and enzyme linked immunoassays. The laboratory has a specific interest in the interface between normal aging and Alzheimer's disease, as well as in non-Alzheimer's degenerative disorders such as Lewy body dementia, corticobasal degeneration, progressive supranuclear palsy and frontotemporal dementia. The primary focus of research on aging is neuropathologic characterization of brains of individuals who had been prospectively and longitudinally evaluated during life. These studies aim to determine differences in a range of biologic parameters in brains of people with normal cognitive, mild cognitive impairment and dementia. Their focus on Parkinson's disease is to identify preclinical Parkinson's disease in order to develop means for early diagnosis.

Proper citation: Mayo Clinic Jacksonville: Neuropathology and Microscopy (RRID:SCR_008753) Copy   

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http://www.mssm.edu/research/centers/alzheimers-disease-research-center/

A research facility and clinical program that is dedicated to the study and the treatment of both normal aging and Alzheimer's disease. This facility will accommodate requests for its resources (for example, data or tissue) from investigators that are not funded by the ADRC. Their team is composed of experts in geriatrics, geriatric psychiatry and psychology, neurology, pathology, and radiology. All team members work to provide services to those with memory disorders. This center sponsors educational programs for healthcare professionals and community groups. Data from the ADRC cores are available to all ADRC investigators after approval from the PI who collected the data. Data generated by the ADRC cores are communicated to the National Alzheimer's Coordinating Center (NACC) and can be available through them. Tissue can be distributed after approval of the Tissue Allocation Committee, and can be used for further research.

Proper citation: Mount Sinai Alzheimer's Disease Research Center (RRID:SCR_008780) Copy   

•   Source: SciCrunch Registry

http://alzheimers.med.umich.edu/research/resources-for-investigators/

An organization that provides scientists with human tissue from Alzheimer's patients and patients with related brain disorders. Brain tissue is collected from research studies at the University of Michigan, as well as other research centers, and are donated by the families of the patients or the participants themselves. Tissues that are present in the Brain Bank are pre-characterized by pathologists and can be provided to researchers upon request.

Proper citation: Michigan Alzheimer's Disease Center Brain Bank (RRID:SCR_008774) Copy   

•   Source: SciCrunch Registry