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https://www.albany.edu/genomics/microarray-ngs.html

Provides services for DNA microarrays for large scale analysis of gene expression,gene regulation, exon splicing, epigenetics. Provides instrumentation for scanning of protein arrays.Offers services in RNA sequencing, ChIP-seq, ChIRP-seq, metagenomics and miRNA sequencing.Provides bioinformatics tools for analysis of results of microarray and sequencing experiments. Houses Illumina Nextseq500 and Ion PGM platforms for next generation sequencing. Provides instruments for Next gen sequencing including Illumina, MinIon, Wafergen-Takara, 10x genomics and for DNA microarrays including Affymetrix, Agilent.

Proper citation: University at Albany SUNY Center for Functional Genomics Microarray and Next Gen Sequencing Core Facility (RRID:SCR_018262) Copy   

•   Source: SciCrunch Registry

http://nemoursresearch.org/cores/bcl/

Develops research projects in pediatric genetics and provides essential services in molecular biology and genetics to Nemours clinicians and research staff and to affiliates researchers of University of Delaware and Thomas Jefferson University. Resource for staff of Alfred I. duPont Hospital for Children, Nemours affiliates, COBRE / INBRE investigators and outside customers. Offers expertise in molecular genetics and genomics. Operates according to policies set forth by federal CLIA standards.Services provided include Ion Torrent PGM Next Generation Sequencing, QuantStudio (QS) 3D Digital PCR, Cell Line Authentication, Nucleic Acid Quality Number (AATI Fragment Analyzer),Genotyping including Allelic Discrimination Probes (SNP Real-Time PCR), Affymetrix Microarray (CNV CytoScan, SNP arrays), Fragment Analysis (Capillary Electrophoresis up to 1200 bp), DNA Sequencing (Sanger Sequencing), Expression Analysis including Affymetrix Microarray (global gene expression, transcriptome assays), Pathway-focused Real-Time qPCR (mRNA and miRNA). Shared Instrumentation including Beckman Biomek 3000 Liquid Handler, NanoDrop 2000c, ABI7900 384-well Real-Time Genetic Analyzer, PCR Tamer, Thermocyclers.

Proper citation: Nemours Biomolecular Core Facility (RRID:SCR_018265) Copy   

•   Source: SciCrunch Registry

https://www.colorado.edu/center/stemtech/

Shared facility provides space for culturing human induced plurupotent stem cells on second floor of Porter Biosciences. Provides biosafety cabinets,CO2 and variable oxygen control incubators, inverted phase contrast microscopes, and sterile dissection hood equipped with dissecting microscope and heated stage,inverted fluorescence microscopes with live-cell time-lapse capabilities, centrifuges, liquid nitrogen cryostorage space, refrigerators, freezers, water baths, dedicated bioengineering space, and viral expression core. Routine mycoplasma testing is performed in-house and karyotyping services are carried out via contract.

Proper citation: Colorado University at Boulder Stem Cell Research and Technology Resource Center Core Facility (RRID:SCR_018994) Copy   

•   Source: SciCrunch Registry

https://jcesom.marshall.edu/research/office-of-research-and-graduate-education/core-facilities/genomics/

Core provides services including high throughput next generation sequencing (NGS) to support whole genome, whole exome, RNA-Seq, single cell RNA-Seq, microbiome and global chromatin and methylation studies, biostatistical and bioinformatic support for NGS projects, access to DNA/RNA sequence analysis software, automated Sanger DNA sequencing, genotyping and RNA/DNA quality assessment, access to shared instrumentation such as plate readers, real time thermal cyclers, Agilent Bioanalyzers, fluorimeters, and spectrophotometers.

Proper citation: Marshall University School of Medicine Genomics Core Facility (RRID:SCR_018885) Copy   

•   Source: SciCrunch Registry

https://med.virginia.edu/gatc/

Core offers instrumentation and expertise in all areas of bulk and single cell NGS genomics and transcriptomics, as well as training to access core shared instrumentations. Services include RNA Seq, CHIP Seq, ATAC Seq, Amplicon DNA Seq, 16S ribosomal gene sequencing, shot gun sequencing for small genomes and whole exome sequencing.10X Genomics resources include single cell CNV, VDJ, and 3 or 5 RNA seq as well as linked reads.Core provides real time and droplet digital PCR services most suitable for targeted gene expression, SNP genotyping and CNV discovery.

Proper citation: Virginia University School of Medicine Genome Analysis and Technology Core Facility (RRID:SCR_018883) Copy   

•   Source: SciCrunch Registry

https://education.musc.edu/colleges/medicine/departments/pharmacology/redox-center/cores/bioenergetics-profiling-core

Core provides several technologies that enable researchers to quantify fluxes of these metabolic reactions in cells, tissues, organoids and small animal models such as zebrafish embryos and nematodes.Technologies include high resolution respirometry using XF technology from Seahorse Biosciences/Agilent. Instrumentation utilizes 96-well microplates to provide sufficient sample numbers to provide flux profiles of glycolysis, mitochondrial respiration, fatty acid oxidation, glutamine utilization and other related metabolic processes. Rapid, high-throughput imaging optimized to XF plate architecture provides normalization of cell/tissue numbers, health, and other.Provides training, data analyses support and aid in experimental design.

Proper citation: South Carolina Medical University Bioenergetics Profiling Core Facility (RRID:SCR_017953) Copy   

•   Source: SciCrunch Registry

https://biomedicalsciences.unimelb.edu.au/departments/department-of-biochemistry-and-pharmacology/research/services/bomp

Core provides access to fluorescence microscopy equipment including Deltavision OMX Blaze Super Resolution (3D-SIM/SMLM), Leica SP8 inverted confocal, La Vision Ultramicroscope II Lightsheet Microscope,Nikon Andor WD spinning disk, Nikon A1R inverted confocal x2, Olympus FV-MPERS Multi Photon,Olympus FV3000 inverted confocal (live cell) ISS Fast-FLIM, Perkin Elmer Operetta High Content Imaging, Zeiss LSM800 upright Airyscan, Zeiss LSM880 upright Airyscan fast, Zeiss Elyra/LSM880 inverted (live cell), super resolution (Airyscan/SMLM). Staff can help with image analysis, super resolution microscopy, fluorescence lifetime imaging microscopy, high content imaging and light sheet microscopy techniques.

Proper citation: University of Melbourne Biological Optical Microscopy Platform (BOMP) Core Facility (RRID:SCR_018888) Copy   

•   Source: SciCrunch Registry

https://www.colorado.edu/facility/biokem/

Provides single particle cryo EM and cryo tomography of plunge frozen samples. Using Titan Krios G3i for high resolution data collection on Gatan K3 Direct Detection Camera facility is able to offer data collection at atomic level resolution.Facility uses Serial EM for SPA and cryo-ET data acquisition.

Proper citation: Colorado University at Boulder BioChemistry Krios Electron Microscopy Core Facility (RRID:SCR_019057) Copy   

•   Source: SciCrunch Registry

https://www.forsyth.org/research/services/

Core offers micro 3D X-ray imaging of small samples in high resolution and provides images and quantitative analyses of internal structures of ex vivo samples without any destructive procedures.Scanco CT40 system allows for visualization, measurement, and quantification of the structure of mineralized specimens. Contrast reagents permit visualization of soft tissue structures such as blood vessels.System creates 3D model from stack of 2D X-ray images taken around single axis of rotation. High-resolution scanner can capture detail at resolution of 6 to 32 microns. Non- destructive nature of this technology allows investigators to carry out complementary analyses of the same sample. There are two dedicated workstations for analyzing microCT data, the SCANCO analysis software or the Amira software package with XImagePAQ extension.

Proper citation: Forsyth Institute Micro Computed Tomography Core Facility (RRID:SCR_021180) Copy   

•   Source: SciCrunch Registry

https://www.colorado.edu/lab/cufemm/

Facility features electron microscopes housed in vibration, static-free, and temperature-controlled environment.

Proper citation: Colorado University at Boulder Facility for Electron Microscopy of Materials Core Facility (RRID:SCR_019306) Copy   

•   Source: SciCrunch Registry

https://www.colorado.edu/facility/mimic/

Facility provides specialized services for assessment of material properties, chemistry and structure across multiple length scales with emphasis on assessment of biological tissues, biomaterials, and biologically inspired systems.

Proper citation: Colorado University at Boulder Materials Instrumentation and Multimodal Imaging Core Facility (RRID:SCR_019307) Copy   

•   Source: SciCrunch Registry

https://www.colorado.edu/sharedinstrumentation/core-facilities/biofrontiers-sequencing-core

Core instruments include Agilent Bioanalyzer 2100 system provides sizing, quantitation and quality control of DNA, RNA and proteins, Illumina MiSeq sequencer, able to sequence prepared Illumina DNA or RNA libraries at low- to mid- output (0.75 to 13 Gbp per run), Illumina NextSeq sequencer capable of sequencing Illumina DNA or RNA libraries, QuantStudio 6 Real-Time PCR uses fluorescence detection method for quantitative and qualitative analysis of nucleic acid sequences including gene expression, regulation and variation, Qubit Fluorimeter 3.0 capable of measuring DNA or RNA concentrations with high accuracy.

Proper citation: Colorado University at Boulder BioFrontiers Next-Gen Sequencing Facility Core Facility (RRID:SCR_019308) Copy   

•   Source: SciCrunch Registry

http://smrc.colorado.edu/facilities/xrd_saxs.html

Provides cutting edge capabilities for probing large lengthscale structures such as polymers, biological macromolecules, meso- and nano-porous materials, and molecular self-assemblies.Techniques that can be applied to study materials include SAXS, GISAXS, WAXS, and GIWAXS. The 30W Xenocs Genix 3D x-ray source and state-of-the-art Dectris Eiger R 1M detector provide an excellent way to probe almost any material of interest. In-situ x-ray studies may be carried out using temperature controlled sample holders in both SAXS and GISAXS modes..

Proper citation: Colorado University at Boulder Soft Materials Research Center X-Ray Diffraction Facility Core Facility (RRID:SCR_019304) Copy   

•   Source: SciCrunch Registry

https://biotech.wisc.edu/age/

Provides services and expertise to unlock genome editing tools to advance your research. Routinely generates new genome edited models, particularly mouse, rats, swine, and cell lines, as well as supports in vivo editing, novel preclinical therapeutic strategies, pooled lentiCRISPR screening, and other applications.

Proper citation: University of Wisconsin-Madison Advanced Genome Editing Laboratory (RRID:SCR_021070) Copy   

•   Source: SciCrunch Registry

https://www.colorado.edu/sharedinstrumentation/core-facilities/flow-cytometry-shared-core

Provides instruments including BD Accuri C6 Cytometer with Automated, multisampler/Flow Cytometer,BDFACSCelesta Flow Cytometer Analyzer,BD FACSAria Fusion Cell Sorter.

Proper citation: Colorado University at Boulder Flow Cytometry Shared Core Facility (RRID:SCR_019309) Copy   

•   Source: SciCrunch Registry

https://web.sas.upenn.edu/electronicshop/

Provides electronic design services and medical device development including Embedded systems (Firmware, Hardware, and Software solutions), Electronic prototype design services,PLM (Product Life-cycle Management) for electronic design. Supports Product Management from concept to final customer deployment. Expertise to make electronic device complete consumer product that can be deployed for mass production,Sustaining and maintenance engineering for electronic products,Consulting services in the areas of CE/FCC compliance, EMI, and ESD for lab products and certain consumer electronics,Troubleshooting and repair of released electronic systems.

Proper citation: University of Pennsylvania Penn Electronic Design Shop Core Facility (RRID:SCR_021107) Copy   

•   Source: SciCrunch Registry

https://fccf.mskcc.org/

Provides advanced instrumentation as well as high level technical and scientific expertise in multi dimensional Flow Cytometry and Cell Sorting, to facilitate science, improve the quality, and advance the scope of MSK research.

Proper citation: Memorial Sloan Kettering Cancer Center Flow Cytometry Core Facility (RRID:SCR_021105) Copy   

•   Source: SciCrunch Registry

https://www.colorado.edu/facility/biomolecular-x-ray-crystallography/

Provides resources for crystallization and structure determination of biological macromolecules and complexes. Supports research in the Department of Biochemistry. We are happy to extend our help to researchers from the broader CU community and to researchers outside the university, if time and availability allow us too.

Proper citation: Colorado University at Boulder Macromolecular X-ray Crystallography Core Facility (RRID:SCR_019310) Copy   

•   Source: SciCrunch Registry

https://medicine.uky.edu/centers/cobre/genetic-technologies-core

Core provides services related to manipulation and delivery of nucleic acids to biological systems. Services include Production and titering of recombinant viral vectors,including Lentiviruses, Adenoviruses, and Adeno associated viruses;Subcloning;Tagging of open reading frames;Development of plasmids and/or RNAs for CRISPR/Cas manipulation;piggyBac transposon delivery systems;Real-time PCR analysis;Recombineering;In vitro transcription; Core maintains stock of plasmids that provide components for building constructs envisioned by investigator and provides consultative services.Provides training opportunities in the technologies described above, either as a for-credit, one semester class or on a project-related, fee-based basis.

Proper citation: University of Kentucky College of Medicine Genetic Technologies Core Facility (RRID:SCR_021285) Copy   

•   Source: SciCrunch Registry

https://cancer.dartmouth.edu/scientists-researchers/mouse-modeling

Supports generation and utilization of genetically modified mice, design and production of genetic constructs with methods including yeast and E.coli recombineering, ES cell targeting (transfection, drug selection, and expansion). Produces transgenic mice: DNA injections into oocytes, ES cell injections into blastocysts.Provides humanized immune system mouse models.Offers start to finish experiment services to assist your many needs, please ask for more info.Other services include animal husbandry, IP and IV injections, blood drawing, necropsy and surgeries- embryo transfers, ovariectomy, vasectomy, tumor removal.

Proper citation: Dartmouth Geisel School of Medicine Mouse Modeling Core Facility (RRID:SCR_021284) Copy   

•   Source: SciCrunch Registry