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Stem cell company focused on developing and marketing products to treat medical conditions in the inflammatory, autoimmune, orthopedic and cardiovascular areas. Now part of Smith and Nephew.
Proper citation: Osiris Therapeutics (RRID:SCR_004233) Copy
http://openconnectomeproject.org/
THIS RESOURCE IS NO LONGER IN SERVICE. Documented on January 9, 2023. Connectomes repository to facilitate the analysis of connectome data by providing a unified front for connectomics research. With a focus on Electron Microscopy (EM) data and various forms of Magnetic Resonance (MR) data, the project aims to make state-of-the-art neuroscience open to anybody with computer access, regardless of knowledge, training, background, etc. Open science means open to view, play, analyze, contribute, anything. Access to high resolution neuroanatomical images that can be used to explore connectomes and programmatic access to this data for human and machine annotation are provided, with a long-term goal of reconstructing the neural circuits comprising an entire brain. This project aims to bring the most state-of-the-art scientific data in the world to the hands of anybody with internet access, so collectively, we can begin to unravel connectomes. Services: * Data Hosting - Their Bruster (brain-cluster) is large enough to store nearly any modern connectome data set. Contact them to make your data available to others for any purpose, including gaining access to state-of-the-art analysis and machine vision pipelines. * Web Viewing - Collaborative Annotation Toolkit for Massive Amounts of Image Data (CATMAID) is designed to navigate, share and collaboratively annotate massive image data sets of biological specimens. The interface is inspired by Google Maps, enhanced to allow the exploration of 3D image data. View the fork of the code or go directly to view the data. * Volume Cutout Service - RESTful API that enables you to select any arbitrary volume of the 3d database (3ddb), and receive a link to download an HDF5 file (for matlab, C, C++, or C#) or a NumPy pickle (for python). Use some other programming language? Just let them know. * Annotation Database - Spatially co-registered volumetric annotations are compactly stored for efficient queries such as: find all synapses, or which neurons synapse onto this one. Create your own annotations or browse others. *Sample Downloads - In addition to being able to select arbitrary downloads from the datasets, they have also collected a few choice volumes of interest. * Volume Viewer - A web and GPU enabled stand-alone app for viewing volumes at arbitrary cutting planes and zoom levels. The code and program can be downloaded. * Machine Vision Pipeline - They are building a machine vision pipeline that pulls volumes from the 3ddb and outputs neural circuits. - a work in progress. As soon as we have a stable version, it will be released. * Mr. Cap - The Magnetic Resonance Connectome Automated Pipeline (Mr. Cap) is built on JIST/MIPAV for high-throughput estimation of connectomes from diffusion and structural imaging data. * Graph Invariant Computation - Upload your graphs or streamlines, and download some invariants. * iPad App - WholeSlide is an iPad app that accesses utilizes our open data and API to serve images on the go.
Proper citation: Open Connectome Project (RRID:SCR_004232) Copy
Center whose interests and activities encompass several facets of gastrointestinal regulatory physiology and cell biology. It provides an infrastructure to support basic, translational and clinical research and to facilitate interdisciplinary research and training activities in digestive diseases.
Proper citation: CURE - Digestive Diseases Research Center (RRID:SCR_004238) Copy
http://www.cancerdiagnosis.nci.nih.gov/
National program to improve the diagnosis and assessment of cancer by moving scientific knowledge into clinical practice by coordinating and funding resources and research for the development of innovative in vitro diagnostics, novel diagnostic technologies and appropriate human specimens. The Cancer Diagnosis Program is divided into four branches: Biorepository and Biospecimen Research Branch (BBRB), Diagnostic Biomarkers and Technology Branch (DBTB), Diagnostics Evaluation Branch (DEB), and the Pathology Investigation and Resources Branch (PIRB).
Proper citation: CDP (RRID:SCR_004236) Copy
http://proteome.gs.washington.edu/software/bibliospec/documentation/index.html
BiblioSpec enables the identification of peptides from tandem mass spectra by searching against a database of previously identified spectra. This suite of software tools is for creating and searching MS/MS peptide spectrum libraries. BiblioSpec is available free of charge for noncommercial use through an interactive web-site at http://depts.washington.edu/ventures/UW_Technology/Express_Licenses/bibliospec.php The BiblioSpec package contains the following programs: * BlibBuild creates a library of peptide MS/MS spectra from MS2 files. * BlibFilter removes redundant spectra from a library. * BlibSearch searches a spectrum library for matches to query spectra, reporting the results in an SQT file. In addition to the primary programs, the following auxiliary programs are available: * BlibStats writes summary statistics describing a library. * BlibToMS2 writes a library in MS2 file format. * BlibUpdate adds, deletes, or annotates spectra. * BlibPpMS2 processes spectra (bins peaks, removes noise, normalizes intensity) as done in BlibSearch and prints the resulting spectra to a text file. Several reference libraries are available for download. These libraries are updated regularly and are for use under the Linux operating system. You will find libraries for * Escherichia coli * Saccharomyces cerevisiae * Caenorhabditis elegans
Proper citation: BiblioSpec (RRID:SCR_004349) Copy
http://www.kyushu-u.ac.jp/english/
Japanese national university located in Fukuoka, in the island of Kyushu.
Proper citation: Kyushu University; Fukuoka; Japan (RRID:SCR_004149) Copy
Medpedia is an open platform connecting people and information to advance medicine. This wiki is the collaborative encyclopedia and resource for information about health, medicine and the body. Only physicians and Ph.D.s are allowed to edit the Articles on Medpedia after they create an account and are approved as an Editor. Non-Editors can create an account and then suggest changes that must be approved by an Editor before going live on the site. To suggest changes, click the link Suggest Changes at the top of Article Pages. Intended Uses and Benefits: * Reference source for both medical professionals and the lay-public covering information about health, medicine and the body * Forum for individuals and groups to be recognized for their areas of expertise * Clearinghouse of bio-medical journal articles, data, research, and educational materials * Forum for debating emerging issues * Platform for advancing medical knowledge Medpedia Portals - Adult Primary Care, Allergy and Immunology, Anatomy, Cardiology, Emergency Medicine, Endocrinology, Epidemiology, Gastroenterology and Hepatology, General Medicine, Infectious Diseases, Internal Medicine, Neurology & Neurobiology, Nutrition, OB/GYN and Reproductive Health, Oncology, Orthopedics, Pathology, Pediatrics, Pharmacology, Psychiatry, Public Health, Pulmonology, Rheumatology, Women''s Health In association with Harvard Medical School, Stanford School of Medicine, Berkeley School of Public Health, University of Michigan Medical School and other leading global health organizations, Medpedia will be a commons for the gathering of the information and people critical to health care.
Proper citation: Medpedia (RRID:SCR_004269) Copy
Launched in 2005, the Simons Foundation Autism Research Initiative (SFARI) is a research campaign within the Simons Foundation''s overall suite of programs. SFARI''s mission is to improve the diagnosis and treatment of autism spectrum disorders by funding, catalyzing and driving innovative research of the greatest quality and relevance. Although SFARI''s priority is to benefit individuals challenged by these disorders, its efforts are certain to yield insights into the neural mechanisms of fundamental human capabilities, thereby promoting the broader mission of the Simons Foundation to advance the frontiers of research in the basic sciences and mathematics. Autism spectrum disorders are a set of complex developmental disorders characterized by persistent deficits in social communication and interaction, as well as restricted behaviors, interests or activities. The Centers for Disease Control and Prevention estimates that roughly 1 in 110 children in the U.S. have autism, with many more boys affected than girls. These disorders cost the U.S. economy an estimated $35 billion dollars each year in direct care costs and lost productivity, and extract an incalculable human toll.
Proper citation: SFARI - Simons Foundation Autism Research Initiative (RRID:SCR_004261) Copy
http://webvision.med.utah.edu/
Online textbook that has evolved into an interactive, dynamic blog that covers all things related to the bioscience of the visual system. It summarizes recent advances in knowledge and understanding of the visual system through dedicated chapters and evolving discussion to serve as a clearing house for all things related to retina and vision science.
Proper citation: Webvision - The Organization of the Retina and Visual System (RRID:SCR_004254) Copy
http://www.guthyjacksonfoundation.org/
The Guthy-Jackson Charitable Foundation is dedicated to funding basic science research to find answers that will lead to the prevention, clinical treatment programs and a potential cure for Neuromyelitis Optica (NMO) Spectrum Disease. The decision to create our Foundation came from a personal family crisis. Our daughter was officially diagnosed with NMO in June 2008. Since that time, we have met with many clinicians and researchers in order to understand what this means for our beautiful daughter and our family. Additionally, we have gathered and read every piece of information and NMO research article that is available on the Web. We are now beginning to understand that NMO is not only considered an orphan disease, but that very little research is available. We met with the All Greater Good Foundation in early July 2008 when it became clear that there is little-to-no funding available to research this rare and often misunderstood disease. We joined hands with the All Greater Good Foundation to immediately begin our work, and thus, The Guthy-Jackson Charitable Foundation was born. The Guthy-Jackson Charitable Foundation is dedicated to funding biomedical research in the search to understand the pathophysiology and biochemistry of NMO Spectrum Disease. It is our greatest hope that together we will reverse the effects of NMO and eventually cure this disease.
Proper citation: Guthy-Jackson Charitable Foundation (RRID:SCR_004441) Copy
An open source and domain independent Workflow Management System ����?? a suite of tools used to design and execute scientific workflows and aid in silico experimentation. Taverna Workbench now has support for service sets, offline workflow editing, workflow validation, improved workflow run monitoring, and the pausing and canceling of workflow runs. The command line tool allows you to run workflows outside of the workbench and is available as a stand-alone download or bundled with the Taverna Workbench 2.2.0 download. The Taverna suite is written in Java and includes the Taverna Engine (used for enacting workflows) that powers both the Taverna Workbench (the desktop client application) and the Taverna Server (which allows remote execution of workflows). Taverna is also available as a Command Line Tool for a quick execution of workflows from a terminal. Taverna 2.2.0 includes * Copy/paste, shortcuts, undo/redo, drag and drop * Animated workflow diagram * Remembers added/removed services * Secure Web services support * Secure access to resources on the web * Up-to-date R support * Intermediate values during workflow runs * myExperiment integration * Excel and csv spreadsheet support * Command line tool
Proper citation: Taverna (RRID:SCR_004437) Copy
THIS RESOURCE IS NO LONGER IN SERVICE, documented October 13, 2014. The resource has moved to the NIDDKInformation Network (dkNET) project. Contact them at info_at_dknet.org with any questions. Database of large pools of data relevant to the mission of NIDDKwith the goal of developing a community-based network for integration across disciplines to include the larger DKuniverse of diseases, investigators, and potential users. The focus is on greater use of this data with the objective of adding value by breaking down barriers between sites to facilitate linking of different datasets. To date (2013/06/10), a total of 1,195 resources have been associated with one or more genes. Of 11,580 total genes associated with resources, the ten most represented are associated with 359 distinct resources. The main method by which they currently interconnect resources between the providers is via EntrezGene identifiers. A total of 780 unique genes provide the connectivity between 3,159 resource pairs across consortia. To further increase interconnectivity, the groups have been further annotating their data with additional gene identifiers, publications, and ontology terms from selected Open Biological and Biomedical Ontologies (OBO).
Proper citation: dkCOIN (RRID:SCR_004438) Copy
MPI Research exists to provide comprehensive discovery, safety evaluation, bioanalytical, and analytical services that meet the requirements of biopharmaceutical, medical device, animal health, and chemical companies as we partner globally to bring safer and more effective products to the world. Our goal is to exceed the expectations of our Sponsors and maintain the highest respect in our industry by providing customized, responsive, and on-time services that add value to our Sponsors'' efforts to discover, develop, and enhance products in regulated international environments. We excel as a high performance, high quality organization because of our scientific knowledge and experience, integrity, trust, teamwork, and dedication to strong and enduring Sponsor relationships. MPI Research has conducted thousands of drug safety, discovery, bioanalytical, and analytical studies. We offer extensive support and resources including, but not limited to * A wide and diverse range of classes of compounds * All routes of administration except inhalation * Studies with numerous species and models * Comprehensive reporting capabilities Flexibility and ample capacity enable us to * Accommodate multiple requirements simultaneously * Adjust schedules readily * Produce results quickly Responding to a broad spectrum of research needs: Working in partnership with pharmaceutical, biotech, medical device, and chemical companies, we conduct customized preclinical research throughout the discovery and development process, from early proof of concept testing to regulatory submissions, including IND, EPA/OPPTS, NDA, PMA, and 510K.
Proper citation: MPI Research (RRID:SCR_004397) Copy
http://magnet.c2b2.columbia.edu/
The mission of the Center for the Multiscale Analysis of Genomic and Cellular Networks (MAGNet) is to develop novel Structural and Systems Biology methods and tools for the dissection of molecular interactions in the cell and for the interaction-based elucidation of cellular phenotypes. These tools are made freely available to the the members of the research community. They are also validated in the context of the Center''''s own research program through collaborative projects with experimental biologists. MAGNet is one of 7 National Centers for Biomedical Computing (NCBC). These Centers, in conjunction with individual investigator awards, are creating a networked effort to build the computational infrastructure for biomedical computing in the nation. The NCBC program is devoted to all facets of biomedical computing, from basic research in computational science to providing the tools and resources that biomedical and behavioral researchers need to do their work. In addition to carrying out fundamental research the NCBCs play a major role in educating and training researchers to engage in biomedical computing. MAGNet is also one of 12 inter-disciplinary Centers for Cancer Systems Biology (CCSBs), a component of the National Cancer Institute''''s Integrative Cancer Biology Program. The CCSBs provide a core framework for applying systems biology approaches to cancer research through the development and implementation of computational models of processes relevant to cancer prevention, diagnostics and therapeutics. The CCSBs seek to integrate experimental biology with mathematical modeling to foster new insights in the biology and new approaches to the management of cancer. MAGNet''''s Training Core ensures that the methods developed by the Center are integrated into the educational offerings of Columbia University''''s Medical School.
Proper citation: MAGNet - Multiscale Analysis of Genomic and Cellular Networks (RRID:SCR_004399) Copy
http://okcam.cbi.pku.edu.cn/ontology.php
CAMO (Cell Adhesion Molecule Ontology) is a set of standard vocabulary that provide a hierarchical description of cell adhesion molecules and their functions. We compiled a list for cell adhesion molecules by integrating Gene Ontology annotations, domain structure information, and keywords query against NCBI Entrez Gene annotations. Totally 496 unique human genes were identified to function as cell adhesion molecules, which is by far the most comprehensive dataset including cadherin, immunoglobulin/FNIII, integrin, neurexin, neuroligan, and catenin families. CAMO was constructed as a directed acyclic graph (DAG) using DAG-Edit to input, manage and update data. We annotated each term with name, definition and source references, as well as the relationship to other terms, based on manual reviews of domain architecture and functional annotations. If vertices represent terms and the relationships between terms are represented by edges, the terms in a DAG can be connected via a directed graph without cycles. CAMO thus provides a hierarchical description of functions of CAMs with five top-level categories: CAM gene families, CAM genetics, CAM regulation, CAM expression and CAM diseases. Each top-level term is further divided into several categories to describe the functions in detail.
Proper citation: CAMO - Cell Adhesion Molecule Ontology (RRID:SCR_004392) Copy
The Biomedical Research Program (PIB) of the School of Medical Sciences was created in 2007, after a Collaboration Protocol was established between UCA and the National Council of Scientific and Technical Research (CONICET). Research at PIB aims at unraveling the molecular, biochemical and genetic aspects of human diseases, therefore contributing to understanding complex pathologies. Research Groups include: * Molecular and Cell Biology Lab (LBCM) - Group leader: Tom��s A. Santa Coloma, Ph.D. * Nanotechnology Lab - Group leader: Tom��s A. Santa Coloma, Ph.D. * Molecular Neurobiology Lab - Group leader: Francisco J. Barrantes, Ph.D.
Proper citation: Biomedical Research Program UCA (RRID:SCR_004395) Copy
http://en.wikibooks.org/wiki/Diagnostic_Radiology
This is a wiki on diagnostic radiology. Major topics include General Types of Radiology, Imaging Modalities, Radiography, CT scanning, Sonography, MRI Magnetic Resonance Imaging, Nuclear medicine, Normal Radiological Anatomy, Imaging of Specific Anatomic Regions, Diagnosis of Specific Anatomic Regions, Imaging in Pediatric Radiology, and External resources. Radiology is the branch of medical science dealing with medical imaging. It may use x-ray machines or other such radiation devices. It also uses techniques that do not involve radiation, such as MRI and ultrasound. The medical information provided on Wikibooks is, at best, of a general nature and cannot substitute for the advice of a medical professional (for instance, a qualified doctor/physician, nurse, pharmacist/chemist, and so on). Wikibooks is not a doctor.
Proper citation: Diagnostic Radiology (RRID:SCR_004427) Copy
An accurate and reliable method for identifying athletes with head trauma, and a strong candidate rapid sideline screening test for concussion. The test is able to capture impairments of eye movement, attention, language and other symptoms of impaired brain function. It is a physical method of evaluating visual tracking and saccadic eye movements is based on the time to perform rapid number naming. It involves reading aloud a series of single digit numbers from left to right on three test cards. Participants are asked to read the numbers on each card from left to right as quickly as possible but without making any errors. The sum of the three test card time scores constitutes the summary score for the entire test. The test is a proven indicator of oculomotor inefficiencies regarding eye movements during reading. Published medical studies have determined that deficiencies in saccadic eye movements can be an indicator of mild Traumatic Brain Injury (mTBI) or concussions. Studies have shown that there is a significant relationship between poor oculomotor functions and learning disabilities (including dyslexia detection). Saccadic eye movement deficiencies can be improved with training and correspondingly reading performance also can be improved. Simply put, subjects who don''t perform well on this test are not efficient readers, although because there are many reasons for poor reading unrelated to eye movements, some poor readers do fine on the test. They believe that the test should be in the hands of teachers in order to help them determine if a student''s poor reading performance is related to deficiencies in their ability to move their eyes efficiently.
Proper citation: King-Devick Test (RRID:SCR_004500) Copy
An Antibody supplier
Proper citation: Cell Sciences (RRID:SCR_004502) Copy
https://www.cedarlanelabs.com/
An Antibody supplier
Proper citation: CEDARLANE Laboratories Limited (RRID:SCR_004462) Copy
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