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SciCrunch Registry is a curated repository of scientific resources, with a focus on biomedical resources, including tools, databases, and core facilities - visit SciCrunch to register your resource.

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Resource Name Proper Citation Abbreviations Resource Type Description Keywords Resource Relationships Related Condition Funding Defining Citation Availability Website Status Alternate IDs Alternate URLs Old URLs Parent Organization Resource ID Synonyms Record Last Update Mentions Count
GeneTrail
 
Resource Report
Resource Website
100+ mentions
GeneTrail (RRID:SCR_006250) GeneTrail production service resource, service resource, data analysis service, analysis service resource A web-based application that analyzes gene sets for statistically significant accumulations of genes that belong to some functional category. Considered category types are: KEGG Pathways, TRANSPATH Pathways, TRANSFAC Transcription Factor, GeneOntology Categories, Genomic Localization, Protein-Protein Interactions, Coiled-coil domains, Granzyme-B clevage sites, and ELR/RGD motifs. The web server provides two statistical approaches, "Over-Representation Analysis" (ORA) comparing a reference set of genes to a test set, and "Gene Set Enrichment Analysis" (GSEA) scoring sorted lists of genes., THIS RESOURCE IS NO LONGER IN SERVICE. Documented on September 16,2025. pathway, microarray, enrichment, genomic, proteomic, function, transcription factor, genomic localization, protein-protein interaction, coiled-coil domain, granzyme-b clevage site, motif, bio.tools is listed by: OMICtools
is listed by: Debian
is listed by: bio.tools
is related to: KEGG
is related to: TRANSPATH
is related to: TRANSFAC
is related to: Gene Ontology
has parent organization: Saarland University; Saarbrucken; Germany
PMID:17526521 THIS RESOURCE IS NO LONGER IN SERVICE biotools:genetrail, OMICS_02236 https://bio.tools/genetrail SCR_006250 2026-02-16 09:46:44 106
FuSSiMeG: Functional Semantic Similarity Measure between Gene-Products
 
Resource Report
Resource Website
FuSSiMeG: Functional Semantic Similarity Measure between Gene-Products (RRID:SCR_005738) FuSSiMeG production service resource, service resource, data analysis service, analysis service resource FuSSiMeG is being discontinued, may not be working properly. Please use our new tool ProteinOn. Functional Semantic Similarity Measure between Gene Products (FuSSiMeG) provides a functional similarity measure between two proteins using the semantic similarity between the GO terms annotated with the proteins. Platform: Online tool protein, similarity, gene ontology, gene, ontology, statistical analysis, term enrichment, semantic similarity, analysis, other analysis is listed by: Gene Ontology Tools
is related to: Gene Ontology
is related to: ProteInOn
has parent organization: University of Lisbon; Lisbon; Portugal
Free for academic use nlx_149198 SCR_005738 Functional Semantic Similarity Measure between Gene-Products, Functional Semantic Similarity Measure between Gene Products (FuSSiMeG) 2026-02-16 09:46:32 0
GOEAST - Gene Ontology Enrichment Analysis Software Toolkit
 
Resource Report
Resource Website
10+ mentions
GOEAST - Gene Ontology Enrichment Analysis Software Toolkit (RRID:SCR_006580) GOEAST production service resource, service resource, data analysis service, analysis service resource Gene Ontology Enrichment Analysis Software Toolkit (GOEAST) is a web based software toolkit providing easy to use, visualizable, comprehensive and unbiased Gene Ontology (GO) analysis for high-throughput experimental results, especially for results from microarray hybridization experiments. The main function of GOEAST is to identify significantly enriched GO terms among give lists of genes using accurate statistical methods. Compared with available GO analysis tools, GOEAST has the following unique features: * GOEAST supports analysis for data from various resources, such as expression data obtained using Affymetrix, illumina, Agilent or customized microarray platforms. GOEAST also supports non-microarray based experimental data. The web-based feature makes GOEAST very user friendly; users only have to provide a list of genes in correct formats. * GOEAST provides visualizable analysis results, by generating graphs exhibiting enriched GO terms as well as their relationships in the whole GO hierarchy. * Note that GOEAST generates separate graph for each of the three GO categories, namely biological process, molecular function and cellular component. * GOEAST allows comparison of results from multiple experiments (see Multi-GOEAST tool). The displayed color of each GO term node in graphs generated by Multi-GOEAST is the combination of different colors used in individual GOEAST analysis. Platform: Online tool statistical analysis, gene ontology, high-throughput, microarray, hybridization, gene, visualization, bio.tools is listed by: Gene Ontology Tools
is listed by: Debian
is listed by: bio.tools
is related to: Gene Ontology
has parent organization: Chinese Academy of Sciences; Beijing; China
National Natural Science Foundation of China 30725014;
National Natural Science Foundation of China 90612019;
Ministry of Science and Technology of China 2007CB946901;
Chinese Academy of Sciences KSCX2-YW-R-134;
Chinese Academy of Sciences KSCX2-YW-N-024
PMID:18487275 Free for academic use biotools:goeast, nlx_149248 https://bio.tools/goeast SCR_006580 Gene Ontology Enrichment Analysis Software Toolkit, Gene Ontology Enrichment Analysis Software Toolkit (GOEAST) 2026-02-16 09:46:45 38
GOrilla: Gene Ontology Enrichment Analysis and Visualization Tool
 
Resource Report
Resource Website
100+ mentions
GOrilla: Gene Ontology Enrichment Analysis and Visualization Tool (RRID:SCR_006848) GOrilla production service resource, service resource, data analysis service, analysis service resource A tool for identifying and visualizing enriched GO terms in ranked lists of genes. It can be run in one of two modes: * Searching for enriched GO terms that appear densely at the top of a ranked list of genes or * Searching for enriched GO terms in a target list of genes compared to a background list of genes. gene, genetic, ontology, ontology or annotation visualization, statistical analysis, term enrichment, visualization, analysis, protein is listed by: Gene Ontology Tools
is listed by: OMICtools
is related to: Gene Ontology
European Union FP6 ;
Yeshaya Horowitz Association
PMID:19192299 Acknowledgement requested, Free, Public nlx_80425, OMICS_02282 SCR_006848 Gene Ontology enRIchment anaLysis and visuaLizAtion tool, GOrilla: Gene Ontology Enrichment Analysis Visualization Tool 2026-02-16 09:46:49 492
GOstat
 
Resource Report
Resource Website
100+ mentions
GOstat (RRID:SCR_008535) GOstat production service resource, service resource, data analysis service, analysis service resource GOstat is a tool that allows you to find statistically overrepresented Gene Ontologies within a group of genes. The Gene-Ontology database (GO: http://www.geneontology.org) provides a useful tool to annotate and analyze the function of large numbers of genes. Modern experimental techniques, as e.g. DNA microarrays, often result in long lists of genes. To learn about the biology in this kind of data it is desirable to find functional annotation or Gene-Ontology groups which are highly represented in the data. This program (GOstat) should help in the analysis of such lists and will provide statistics about the GO terms contained in the data and sort the GO annotations giving the most representative GO terms first. Run GOstat: * Go to search form - Computes GO statistics of a list of genes selected from a microarray. * GOstat Display - You can store results from a previously run and view them here, either by uploading them as a file or putting them on a selected URL. * Upload Custom GO Annotations - This allows you to upload your own GO annotation database and use it with GOstat. Variants of GOstat: * Rank GOstat - Takes input from all genes on microarray instead of using a fixed cutoff and uses ranks using a Wilcoxon test or either ranks or pvalues to score GOs using Kolmogorov-Smirnov statistics. * Gene Abundance GOstats - Takes input from all genes on microarray and sums up the gene abundances for each GO to compute statistics. * Two list GOstat - Compares GO statistics in two independent lists of genes, not necessarily one of them being the complete list the other list is sampled from. Platform: Online tool, THIS RESOURCE IS NO LONGER IN SERVICE. Documented on September 16,2025. gene, gene ontology, annotation, statistical analysis, FASEB list is listed by: Gene Ontology Tools
is related to: Gene Ontology
has parent organization: Walter and Eliza Hall Institute of Medical Research; Victoria; Australia
DFG PMID:14962934 THIS RESOURCE IS NO LONGER IN SERVICE nif-0000-30625 SCR_008535 2026-02-16 09:47:12 159
GeneTerm Linker
 
Resource Report
Resource Website
1+ mentions
GeneTerm Linker (RRID:SCR_006385) GTLinker production service resource, service resource, data analysis service, analysis service resource Web application that filters and links enriched output data identifying sets of associated genes and terms, producing metagroups of coherent biological significance. The method uses fuzzy reciprocal linkage between genes and terms to unravel their functional convergence and associations. It can also be accessed through its web service. gene, functional annotation, function, functional metagroup, p-value, annotation, web service is listed by: OMICtools
is related to: Gene Ontology
is related to: KEGG
is related to: InterPro
has parent organization: Spanish National Research Council; Madrid; Spain
PMID:21949701 Acknowledgement requested OMICS_02227 SCR_006385 GeneTerm Linker - post enrichment functional association by non-redundant reciprocal linkage 2026-02-16 09:46:42 2
Magic
 
Resource Report
Resource Website
500+ mentions
Magic (RRID:SCR_006406) MAGIC service resource, data or information resource, database Web based interface for exploring and analyzing a comprehensive maize-specific cross-platform expression compendium. This compendium was constructed by collecting, homogenizing and formally annotating publicly available microarrays from Gene Expression Omnibus (GEO), and ArrayExpress. gene expression, microarray, development stage, annotation, line, perturbation, gene, contrast, pathway, locus tag, bio.tools, FASEB list is listed by: OMICtools
is listed by: bio.tools
is listed by: Debian
is related to: Gene Expression Omnibus
is related to: ArrayExpress
is related to: Plant Ontology
is related to: Gene Ontology
has parent organization: Ghent University; Ghent; Belgium
PMID:24407224 biotools:magic, OMICS_02206 https://bio.tools/magic SCR_006406 MAGIC - MAize Gene expressIon Compendium, MAize Gene expressIon Compendium 2026-02-16 09:46:42 706
Quantitative Enrichment of Sequence Tags
 
Resource Report
Resource Website
10+ mentions
Quantitative Enrichment of Sequence Tags (RRID:SCR_004065) QuEST software resource A Kernel Density Estimator-based package for analysis of massively parallel sequencing data from chromatin immunoprecipitation (ChIP-seq) experiments. genome-wide, transcription factor binding site, chip-seq, transcription factor, binding site, bio.tools is listed by: OMICtools
is listed by: Debian
is listed by: bio.tools
is related to: Gene Ontology
has parent organization: Stanford University; Stanford; California
PMID:19160518 OMICS_00458, biotools:quest https://bio.tools/quest SCR_004065 Quantitative Enrichment of Sequence Tags: QuEST 2026-02-14 02:00:40 49
Tk-GO
 
Resource Report
Resource Website
Tk-GO (RRID:SCR_008855) TkGO software resource Tk-GO is a GUI wrapping the basic functions of the GO AppHandle library from BDGP. GO terms are presented in an explorer-like browser, and behavior can be configured by altering Perl scripts. All available documentation is included in the download. Tk-GO uses the GO database (connects directly to the BDGP database by default) but is user-configurable. Platform: Windows compatible, Mac OS X compatible, Linux compatible, Unix compatible browser, gene, ontology or annotation browser is listed by: Gene Ontology Tools
is related to: Gene Ontology
has parent organization: Illumina
MIT License - Free for academic use nlx_149133 SCR_008855 2026-02-14 02:01:46 0
Spotfire
 
Resource Report
Resource Website
100+ mentions
Spotfire (RRID:SCR_008858) Spotfire software resource The Spotfire Gene Ontology Advantage Application integrates GO annotations with gene expression analysis in Spotfire DecisionSite for Functional Genomics. Researchers can select a subset of genes in DecisionSite visualizations and display their distribution in the Gene Ontology hierarchy. Similarly, selection of any process, function or cellular location in the Gene Ontology hierarchy automatically marks the corresponding genes in DecisionSite visualizations. Platform: Windows compatible analysis, predictive analytics, big data, visualization, gene ontology, annotation, gene expression, functional genomics, gene, function, cellular location, statistical analysis, genomics is listed by: Gene Ontology Tools
is listed by: Metabolomics Workbench
is related to: Gene Ontology
Commercial license. Spotfire is available for purchase (individual license / enterprise use) / Free trial. nlx_149169 SCR_008858 Tibco Spotfire, Spotfire Inc., Spotfire Gene Ontology Advantage Application, Spotfire - TIBCO Software 2026-02-14 02:01:47 474
DynGO
 
Resource Report
Resource Website
1+ mentions
DynGO (RRID:SCR_007009) DynGO software resource DynGO is a client-server application that provides several advanced functionalities in addition to the standard browsing capability. DynGO allows users to conduct batch retrieval of GO annotations for a list of genes and gene products, and semantic retrieval of genes and gene products sharing similar GO annotations (which requires more disk and memory to handle the semantic retrieval). The result are shown in an association tree organized according to GO hierarchies and supported with many dynamic display options such as sorting tree nodes or changing orientation of the tree. For GO curators and frequent GO users, DynGO provides fast and convenient access to GO annotation data. DynGO is generally applicable to any data set where the records are annotated with GO terms, as illustrated by two examples. Requirements: Java Platform: Windows compatible, Linux compatible, Unix compatible gene, annotation, browser, ontology or annotation browser is listed by: Gene Ontology Tools
is related to: Gene Ontology
NSF IIS-0430743 PMID:16091147 Free for academic use nlx_149118 http://gauss.dbb.georgetown.edu/liblab SCR_007009 DynGO: a tool for visualizing and mining of Gene Ontology and its associations 2026-02-14 02:01:26 6
go-db-perl
 
Resource Report
Resource Website
1+ mentions
go-db-perl (RRID:SCR_005721) go-db-perl software resource Software resource that extends the functionality of go-perl (on which it depends) with GO Database access functionality. go-db-perl comes bundled with various scripts and a shell command line interface that can be used as standalone tools. Installation is more involved than for go-perl; you will need a MySQL database plus the requisite DBI and DBD Perl modules. Full installation instructions are included in the download. go-db-perl is in use both to drive AmiGO and internally within Ensembl. Platform: Windows compatible, Mac OS X compatible, Linux compatible, Unix compatible software library, database, gene ontology, database or data warehouse is listed by: Gene Ontology Tools
is related to: AmiGO
is related to: go-moose
is related to: Ensembl
is related to: go-perl
has parent organization: Comprehensive Perl Archive Network
has parent organization: Gene Ontology
Free for academic use nlx_149180 SCR_005721 2026-02-14 02:01:10 1
Manatee
 
Resource Report
Resource Website
50+ mentions
Manatee (RRID:SCR_005685) Manatee software resource Manatee is a web-based gene evaluation and genome annotation tool; Manatee can store and view annotation for prokaryotic and eukaryotic genomes. The Manatee interface allows biologists to quickly identify genes and make high quality functional assignments, such as GO classifications, using search data, paralogous families, and annotation suggestions generated from automated analysis. Manatee can be downloaded and installed to run under the CGI area of a web server, such as Apache. Platform: Online tool, Linux compatible, Solaris gene, genome, annotation, ontology or annotation browser, ontology or annotation editor is listed by: Gene Ontology Tools
is related to: Gene Ontology
has parent organization: J. Craig Venter Institute
has parent organization: University of Maryland School of Medicine; Maryland; USA
has parent organization: SourceForge
Open unspecified license - Free for academic use nlx_149128 SCR_005685 2026-02-14 02:01:10 64
go-perl
 
Resource Report
Resource Website
10+ mentions
go-perl (RRID:SCR_005730) go-perl software resource go-perl is a set of Perl modules for parsing, manipulating and exporting ontologies and annotations. It includes parsers for the OBO and GO gene association file formats. It has a graph-based object model with methods for graph traversal. For more details, see the documentation included with the modules. go-perl comes bundled with XSL (Extensible Stylesheet Language) transforms (which can also be used independently of Perl, provided you have files in OBO-XML format), as well as scripts that can be used as standalone tools. Installation should be simple, provided you have some experience with Perl and CPAN; see the INSTALL file for details. Platform: Windows compatible, Mac OS X compatible, Linux compatible, Unix compatible ontology, annotation, software library, slimmer-type tool, parser is listed by: Gene Ontology Tools
is related to: OBO
is related to: go-moose
is related to: go-db-perl
has parent organization: Comprehensive Perl Archive Network
has parent organization: Gene Ontology
Free for academic use nlx_149190 SCR_005730 2026-02-14 02:01:00 10
BiNGO: A Biological Networks Gene Ontology tool
 
Resource Report
Resource Website
500+ mentions
BiNGO: A Biological Networks Gene Ontology tool (RRID:SCR_005736) BiNGO software resource The Biological Networks Gene Ontology tool (BiNGO) is an open-source Java tool to determine which Gene Ontology (GO) terms are significantly overrepresented in a set of genes. BiNGO can be used either on a list of genes, pasted as text, or interactively on subgraphs of biological networks visualized in Cytoscape. BiNGO maps the predominant functional themes of the tested gene set on the GO hierarchy, and takes advantage of Cytoscape''''s versatile visualization environment to produce an intuitive and customizable visual representation of the results. Platform: Windows compatible, Mac OS X compatible, Linux compatible, Unix compatible gene ontology, gene, ontology, statistical analysis, term enrichment, biological network, plugin, bio.tools is listed by: Gene Ontology Tools
is listed by: bio.tools
is listed by: Debian
is related to: Gene Ontology
is related to: Cytoscape
has parent organization: Ghent University; Ghent; Belgium
PMID:15972284 Open unspecified license - Free for academic use nlx_149196, biotools:bingo https://bio.tools/bingo SCR_005736 Biological Networks Gene Ontology 2026-02-14 02:01:00 790
Functional Annotation
 
Resource Report
Resource Website
1+ mentions
Functional Annotation (RRID:SCR_017519) service resource MGI GO project provides functional annotations for mouse gene products using Gene Ontology. Functional annotation using Gene Ontology (GO). MGI, GO, functional, annotation, mouse, gene, product, Gene Ontology uses: Gene Ontology
has parent organization: Mouse Genome Informatics (MGI)
Free, Freely available SCR_017519 2026-02-14 02:03:13 4
EBIMed
 
Resource Report
Resource Website
1+ mentions
EBIMed (RRID:SCR_005314) EBIMed service resource A web application that combines Information Retrieval and Extraction from Medline. EBIMed finds Medline abstracts in the same way PubMed does. Then it goes a step beyond and analyses them to offer a complete overview on associations between UniProt protein/gene names, GO annotations, Drugs and Species. The results are shown in a table that displays all the associations and links to the sentences that support them and to the original abstracts. By selecting relevant sentences and highlighting the biomedical terminology EBIMed enhances your ability to acquire knowledge, relate facts, discover implications and, overall, have a good overview economizing the effort in reading. protein, gene, annotation, drug, specie, association, database is listed by: OMICtools
is related to: MEDLINE
is related to: PubMed
is related to: Gene Ontology
is related to: UniProt
is related to: NCBI Taxonomy
is related to: MedlinePlus
has parent organization: European Bioinformatics Institute
OMICS_01180 SCR_005314 2026-02-14 02:01:04 1
Coremine Medical
 
Resource Report
Resource Website
1+ mentions
Coremine Medical (RRID:SCR_005323) Coremine Medical service resource Service to access comprehensive information on diseases, drugs, treatments and medical biology. It is ideal for those seeking an overview of a complex subject while allowing the possibility to drill down to specific details. Search results are presented in a dashboard format comprized of panels containing various categories of information ranging from introductory sources to the latest scientific articles. disease, drug, treatment, medical biology, text mining, health, medicine, biology, network, database is listed by: OMICtools
is related to: MeSH
is related to: Entrez Gene
is related to: MEDLINE
is related to: PubMed
is related to: DrugBank
is related to: Gene Ontology
is related to: UniProt
has parent organization: PubGene
NLM ;
European Union FP7 ;
Research Council of Norway ;
Innovation Norway
Copyrighted OMICS_01179 SCR_005323 2026-02-14 02:01:05 6
Gramene
 
Resource Report
Resource Website
500+ mentions
Gramene (RRID:SCR_002829) GR data or information resource, database Curated, open-source, integrated data resource for comparative functional genomics in crops and model plant species to facilitate the study of cross-species comparisons using information generated from projects supported by public funds. It currently hosts annotated whole genomes in over two dozen plant species and partial assemblies for almost a dozen wild rice species in the Ensembl browser, genetic and physical maps with genes, ESTs and QTLs locations, genetic diversity data sets, structure-function analysis of proteins, plant pathways databases (BioCyc and Plant Reactome platforms), and descriptions of phenotypic traits and mutations. The web-based displays for phenotypes include the Genes and Quantitative Trait Loci (QTL) modules. Sequence based relationships are displayed in the Genomes module using the genome browser adapted from Ensembl, in the Maps module using the comparative map viewer (CMap) from GMOD, and in the Proteins module displays. BLAST is used to search for similar sequences. Literature supporting all the above data is organized in the Literature database. In addition, Gramene now hosts a variety of web services including a Distributed Annotation Server (DAS), BLAST and a public MySQL database. Twice a year, Gramene releases a major build of the database and makes interim releases to correct errors or to make important updates to software and/or data. Additionally you can access Gramene through an FTP site. crop, plant genome, genetic, blast, gene, genome, genetic diversity, pathway, protein, marker, quantitative trait locus, comparative map, phenotype, genomics, physiology, comparative, grain, expressed sequence tag, trait, mutation, environment, taxonomy, web service, bio.tools, FASEB list is used by: NIF Data Federation
is listed by: re3data.org
is listed by: bio.tools
is listed by: Debian
is related to: AmiGO
is related to: Gene Ontology
is related to: Plant Ontology
is related to: Trait Ontology
is related to: EnvO
is related to: BioCyc
has parent organization: Cold Spring Harbor Laboratory
has parent organization: Cornell University; New York; USA
is parent organization of: Trait Ontology
is parent organization of: Plant Environmental Conditions
is parent organization of: Plant Trait Ontology
is parent organization of: Cereal Plant Development Ontology
is parent organization of: Cereal Plant Gross Anatomy Ontology
USDA IFAFS 00-52100-9622;
USDA 58-1907-0-041;
USDA 1907-21000-030;
NSF 0321685;
NSF 0703908;
NSF 0851652
PMID:21076153
PMID:17984077
PMID:16381966
Free, Freely available r3d100010856, nif-0000-02926, nlx_65829, biotools:gramene https://bio.tools/gramene
https://doi.org/10.17616/R3GG7M
SCR_002829 GR PROTEIN, RiceGenes, GR REF, GR GENE, Gramene: A Resource for Comparative Grass Genomics, GR QTL 2026-02-14 02:00:19 778
ECgene: Gene Modeling with Alternative Splicing
 
Resource Report
Resource Website
10+ mentions
ECgene: Gene Modeling with Alternative Splicing (RRID:SCR_007634) ECgene data or information resource, database Database of functional annotation for alternatively spliced genes. It uses a gene-modeling algorithm that combines the genome-based expressed sequence tag (EST) clustering and graph-theoretic transcript assembly procedures. It contains genome, mRNA, and EST sequence data, as well as a genome browser application. Organisms included in the database are human, dog, chicken, fruit fly, mouse, rhesus, rat, worm, and zebrafish. Annotation is provided for the whole transcriptome, not just the alternatively spliced genes. Several viewers and applications are provided that are useful for the analysis of the transcript structure and gene expression. The summary viewer shows the gene summary and the essence of other annotation programs. The genome browser and the transcript viewer are available for comparing the gene structure of splice variants. Changes in the functional domains by alternative splicing can be seen at a glance in the transcript viewer. Two unique ways of analyzing gene expression is also provided. The SAGE tags deduced from the assembled transcripts are used to delineate quantitative expression patterns from SAGE libraries available publicly. The cDNA libraries of EST sequences in each cluster are used to infer qualitative expression patterns. est cluster, genome, alternative splicing, splice, gene, mrna, est, annotation, gene modeling, structure, function, gene expression, transcript, genome browser, differential expression, snp is listed by: OMICtools
is related to: Gene Ontology
has parent organization: Ewha Womans University; Seoul; South Korea
PMID:17132829
PMID:15805497
PMID:15608289
nif-0000-02780, OMICS_01884 http://genome.ewha.ac.kr/ECgene/ SCR_007634 ECgene - Genome Annotation for Alternative Splicing 2026-02-14 02:06:00 12

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