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SciCrunch Registry is a curated repository of scientific resources, with a focus on biomedical resources, including tools, databases, and core facilities - visit SciCrunch to register your resource.
http://www.medizinische-fakultaet-hd.uni-heidelberg.de/Home.111344.0.html
Multidisciplinary in vivo core facility equipped with equipment for detailed behavioral analyses and surgical procedures in context of mouse and rat models of neurological, cognitive and psychiatric disorders.Services include Behavioral analyses, Cognitive function,learning and memory, Sensory motor function, Emotional function and social interactions,Pain sensitivity tests, Disease models, Viral gene delivery, stereotactic and surgical manipulations, Optogenetics, In vivo electrophysiology.
Proper citation: University of Heidelberg Interdisciplinary Neurobehavioral Core Facility (RRID:SCR_019153) Copy
https://www.unmc.edu/vcr/cores/vcr-cores/nanoimaging/index.html
Provides service and expert advice to researches in their projects related to nanoimaging studies of molecular systems at single molecule and single cell levels utilizing Atomic Force Microscope, combination of Atomic Force Microscope with Fluorescence Optical Microscope, combination of Atomic Force Microscope with Raman Spectroscopy.
Proper citation: University of Nebraska Medical Center Nanoimaging Core Facility (RRID:SCR_018828) Copy
http://www.med.nyu.edu/ocs/cytometry-and-cell-sorting-core
Facility provides cytometry and cell sorting services. Services include immunophenotyping, cell cycle analysis, and intracellular fluorophore detection. Services can be tailored to research needs, certified cytometrists are available to help plan experiments. Offers online and hands-on training in use of cell analyzers and analysis software.
Proper citation: New York University School of Medicine Langone Cytometry and Cell Sorting Core Facility (RRID:SCR_018827) Copy
https://labnodes.vanderbilt.edu/vger
Provides services, consultation, and collaborations to enable generation, storage and regeneration of genetically altered mice.Services include CRISPR-Cas9 Mouse Editing, Pronuclear Microinjection of DNAs,Sperm or Embryo Cryopreservation,In vitro Fertilization and Rederivation,Genome-Editing Design and Analysis Services.
Proper citation: Vanderbilt University Genome Editing Resource Core Facility (RRID:SCR_018826) Copy
https://research.uky.edu/abebc
Core primary focus is to identify mechanisms linking obesity to cardiovascular disease. Provides equipment and technical expertise for measurement of lean/fat mass and whole body metabolism in mice. Provides equipment for computerized quantitative measurement of oxygen consumption, food intake, water intake, and physical activity in mice.Echo MRI is utilized for non invasive quantitative assessment of lean and fat mass.
Proper citation: Kentucky University, Lexington, Energy Balance and Body Composition Core Facility (RRID:SCR_018825) Copy
https://www.biotech.iastate.edu/Hybridoma/
Core provides services for monoclonal or polyclonal antibodies production,animal immunization, cell fusion and hybridoma culture maintenance, cell culture and maintenance of other cell lines used in biotechnology and virology labs, large scale mammalian cell culture (bioreactor), blood sera collection, antibody purification and isotyping, cryopreservation and cryostorage of cell lines, and ELISA tests.
Proper citation: Iowa State University Hybridoma Core Facility (RRID:SCR_018829) Copy
https://www.danforthcenter.org/our-work/core-facilities/advanced-bioimaging-laboratory/
Core provides instruments for live cell imaging including Leica SP8-X confocal microscope and other fluorescence microscopes. Facility provides workstation for confocal image processing, ancillary equipment required for transmission electron microscopy. Services are provided as self services after user training by IMF staff or as full services done by core facility staff.
Proper citation: Donald Danforth Plant Science Center Advanced Bioimaging Laboratory Core Facility (RRID:SCR_018951) Copy
https://isb3d.pharmacy.vcu.edu/resources/
Core provides services for Molecular Modeling, Biophysical Techniques, X-ray Crystallography, Protein Production,High Throughput Screening. Provided instruments to use after reservation include Clariostar Multimode Plate Reader, Echo 550 Acoustic Liquid Handler, X-Ray Diffractometer.
Proper citation: Virginia Commonwealth University School of Pharmacy Institute for Structural Biology, Drug Discovery and Development Core Facility (RRID:SCR_018832) Copy
Provides development and support of genomics-based research, serving investigators in Nevada and beyond. Staff can be contracted for select services including ABI 3130 DNA sequencing, BD FACSCalibur flow cytometry, Affymetrix microarray processing, Agilent 2100 Bioanalyzer analysis and Qubit analysis. Facility also provides equipment and training for real-time PCR, Western blot/gel/microarray scanning, and analysis of DNA, RNA and protein samples.
Proper citation: Nevada University Genomics Core Facility (RRID:SCR_018272) Copy
Contract Research Org. specializing in custom protein analysis. Services Provided include SDS PAGE analysis, Western Blotting, Mass Spectrometry, protein staining ( silver,coomassie) for academia, federal institutions and industry.
Proper citation: Kendrick Labs Core Facility (RRID:SCR_018271) Copy
Core provides scientific consultation, training and access to shared biophysical equipment for characterization and analysis of macromolecules and their complexes. Facility includes instruments measuring molecular interactions and assessing protein quality by Isothermal Titration Calorimetry (ITC), Surface Plasmon Resonance (SPR), Biolayer Interferometry (BLI), MicroScale Thermophoresis (MST), Differential Scanning Fluorimetry (DSF), Circular Dichroism (CD), Analytical Size Exclusion Chromatography with Multi-Angle Light Scattering (SEC-MALS), and Dynamic Light Scattering (DLS).
Proper citation: Harvard Medical School Center for Macromolecular Interactions Core Facility (RRID:SCR_018270) Copy
Core assists investigators whose research requires molecular marker characterization of cells in suspension as well as isolation of cells based on those markers. Advanced cell sorting and cytometric analyses by Flow or Mass Cytometry are provided.
Proper citation: University of California San Francisco Parnassus Flow Cytometry Core Facility (RRID:SCR_018206) Copy
https://www.bi.vt.edu/services/genomics-sequencing-center
Core for development and application of Next-Generation Sequencing technologies. Provides experimental design consultation, and genomic, transcriptomic, and functional-genomics services. Specializes in development and application of Next-Generation Sequencing technologies and bioinformatics analyses. Instruments include Illumina NovaSeq 6000, Illumina NextSeq 500,Illumina MiSeq,Thermo Ion S5. Services include mRNA-Seq: Stranded and non-stranded, high levels of multiplexing up to 96 or more samples on NovaSeq;Standard amounts, Stranded-Seq: 500 ng total RNA, RIN 8;Low Input amounts, Stranded-Seq: 5 ng to 100 ng total RNA;Ultra Low Input amounts, Non-Stranded-Seq: 1-1000 cells or 10 pg - 10 ng;Total RNA-Seq - Stranded: 5-250 ng;Small RNA-Seq: 1 ug, multiplexing up to 48 samples/NextSeq run;Partially degraded samples - Stranded and Non-Stranded: LCM, FFPE samples, both stranded and non-stranded, 50 -100 ng;Microbial rRNA depletion and RNA-Seq with amounts as low as 1-5 ug of total RNA;Whole Genome Sequencing;Human / Animal / Plant;Microbial;As low as 1 ng De novo Sequencing;Exome/Targeted capture re-sequencing: Enables high sequencing depths;Agilent and Illumina platforms;Human, Mouse, Canine and other species;Targeted re-sequencing: High levels of multiplexing up to 200 samples / MiSeq run;PCR Amplicon sequencing;Illumina and Agilent platforms;ChIP-Seq;Transcription factor analysis;Histone modifications;DNA Methylation;MeDIP- and MBD-Seq;MethylC-Seq;Agilent SureSelect MethylC-Seq;Nucleosome Mapping;FAIRE-Seq and DNAse I-Seq;16S / 18S / ITS amplicon sequencing;Whole Genome Metagenomic sequencing;Metatranscriptomic analysis;DNA/chromatin fragmentation by Covaris DNA / RNA quality analysis: BioAnalyzer / TapeStation assay, Qubit (Picogreen) assays;qPCR services.
Proper citation: Virginia Tech Biocomplexity Institute Genomics Sequencing Center Core Facility (RRID:SCR_017958) Copy
https://hiro.bsd.uchicago.edu/
Assists University of Chicago investigators and research staff with medical imaging exams performed on human subjects for research purposes. Services include acquisition, analysis, collection, de-identification and distribution of image data for basic science research and clinical trials. Services ensure research-related imaging fulfills protocol requirements and allow investigators to obtain HIPAA- and IRB-compliant clinical research data. Provides services for all types of medical imaging, including x-ray, CT, MRI, ultrasound, nuclear medicine, PET, and most types of specialty imaging.
Proper citation: Chicago University Human Imaging Research Office Core Facility (RRID:SCR_018372) Copy
Formerly Center for Genome Research and Biocomputing Core Facility. Functions and facilities include services in genomics, functional genomics, genotyping and imaging.Biocomputing facilities with computing infrastructure, which includes managed cloud and shared resources, data analyses and training are customized to individual needs, including genome assembly and annotation, analysis of RNAseq, GBS, and metagenomics data, and GPU-enabled deep learning analyses.
Proper citation: Oregon State University Center for Quantitative Life Sciences Core Facility (RRID:SCR_018373) Copy
Facility designed to advance biological discovery through quantitative microscopy techniques. Houses multiple imaging technologies ranging from conventional widefield to state-of-the-art Super Resolution/localization microscopies.Offers N-STORM Super Resolution Microscopy,Laser Scanning Confocal Microscopy, Widefield Fluorescence Microscopy,Spinning Disc Confocal Microscopy,Total Internal Reflection Fluorescence (TIRF) Microscopy,Long-Term Imaging with Temperature, Oxygen, Carbon Dioxide, and Humidity Control,High-Content Screening,Analysis Workstation.
Proper citation: Colorado University Boulder BioFrontiers Advanced Light Microscopy Core Facility (RRID:SCR_018302) Copy
Offers high throughput genomics services, technical expertise and support with experimental design and protocol development. Includes Nucleic Acid Services, genetic and genomic DNA analysis with sequencing available in standard, high-throughput and next-generation formats, Genome-wide MicroArray or RNA-seq and targeted RNA analysis, Next Generation Sequencing,Drop Seq.
Proper citation: Pittsburgh University HSCRF Genomics Research Core Facility (RRID:SCR_018301) Copy
https://www.zmb.uzh.ch/en.html
Advanced imaging facility providing various imaging techniques in microscopy. Focus is on techniques, instrumentation and know-how in electron and light microscopy including preparation.
Proper citation: University of Zurich Center for Microscopy and Image Analysis Core Facility (RRID:SCR_019115) Copy
Offers instrumentation and technical capabilities and plays significant consultative role in application of these technologies to basic science projects.Genomic Services include Oligo Synthesis,Gene Expression,Real-Time PCR,PyroSequencing,Next-Generation Sequencing (NGS),DNA Sequencing (Sanger)/Fragment AnalysisSingle Cell Genomics,RNA-DNA QC - Bioanalyzer and Fragment Analyzer QC.Protein Services include Peptide Synthesis,Mass Spectrometry,Protein Analytics - Mass Mapping/Edman Sequencing,Surface Plasmon Resonance (Biacore).
Proper citation: Stanford University School of Medicine Protein and Nucleic Acid Core Facility (RRID:SCR_018668) Copy
Core provides imaging equipment including JEOL 1400 transmission electron microscope with AMT 11 megapixel digital camera,JEOL JSM 6060 scanning electron microscope with attached Oxford INCA energy dispersive spectroscopy detector for element analysis,Nikon Air HD confocal scanning laser microscope, Nikon C2 confocal scanning laser microscope, Andor Spinning Disk confocal microscope, Zeiss LSM 7 Multiphoton confocal microscope, Nikon STORM super-resolution light microscope, Olympus BX50 research microscope for transmitted light, phase contrast, and epi-fluorescence microscopy, Asylum Research MFP-3D BIO atomic force microscope, Asylum Research Cypher Environmental atomic force microscope,Arcturus XT-Ti Laser Capture Microdissector system, Olympus IX70 inverted microscope with associated Applied BioPhysics Electri Cell-Substrate Impedance Sensing (ECIS Ztheta) system, Leica VERSA 8 whole slide imager, Dell workstations containing Molecular Devices MetaMorph image analysis software for complex quantitative image analysis, Indica Labs HALO software, Improvision Volocity, MBR StereoInvestigator.
Proper citation: Vermont University Larner College of Medicine Microscopy Imaging Center Core Facility (RRID:SCR_018821) Copy
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