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SciCrunch Registry is a curated repository of scientific resources, with a focus on biomedical resources, including tools, databases, and core facilities - visit SciCrunch to register your resource.

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Resource Name Proper Citation Abbreviations Resource Type Description Keywords Resource Relationships Related Condition Funding Defining Citation Availability Website Status Alternate IDs Alternate URLs Old URLs Parent Organization Resource ID Synonyms Record Last Update Mentions Count
NIS-Elements
 
Resource Report
Resource Website
1000+ mentions
Rating or validation data
NIS-Elements (RRID:SCR_014329) software application, software resource, software toolkit, data analysis software, data processing software Microscope imaging software suite used with Nikon products. NIS-Elements includes software applications for advanced and standard research, documentation, confocal microscopy, and high-content analysis., THIS RESOURCE IS NO LONGER IN SERVICE. Documented on September 16,2025. element, microscope imaging software, software suite, nikon is listed by: SoftCite
works with: Nikon ECLIPSE Ti2 inverted microscope
THIS RESOURCE IS NO LONGER IN SERVICE SCR_014329 Nikon Instruments Software Elements, NIS Elements, Nikon Instruments Software 2026-02-11 10:58:54 3462
IMAGIC
 
Resource Report
Resource Website
100+ mentions
IMAGIC (RRID:SCR_014447) software application, image analysis software, software resource, data processing software, image processing software An image analysis software that can process spectra and other multi-dimensional data-sets. The software package is aimed at processing large data sets from (cryo-) electron microscopy, especially in the field of single particle analyses. This software can be used with light and raster-tunneling microscopes, computer tomographs, FT-IR spectrometers and other signal collecting devices. This resource provides three-dimensional data processing and angular reconstitution modules that allow the three-dimensional reconstruction with point-group symmetry from the two dimensional electron microscopy projections. These models aid in the analysis of the macromolecules. image analysis, spectra, multi-dimensional data, macromolecule, 3d processing, tomograph, spectrometer, software environment is listed by: SoftCite PMID:8742718 Commercial, Account needed for download SCR_014447 2026-02-11 10:58:55 217
LSM Image Examiner
 
Resource Report
Resource Website
1000+ mentions
Rating or validation data
LSM Image Examiner (RRID:SCR_014344) data management software, software application, software resource Software used to compile images obtained from the Zeiss LSM 510 confocal microscope. The browser can be used for general image archiving and handling and interactive measurement in labs and workgroups. Features include orthogonal sectioning, 3D cut function, 3D view with calculation of single projections, and interactive measurement functions in the overlay dialog, such as scale bar, distance, and area. data management software, image archive, image management, interactive measurement is listed by: SoftCite Available for download http://www.zeiss.com/microscopy/en_us/website/downloads/lsm-image-browser.html http://lsm-image-examiner.software.informer.com SCR_014344 LSM Image Browser 2026-02-11 10:58:54 1508
MassLynx
 
Resource Report
Resource Website
5000+ mentions
MassLynx (RRID:SCR_014271) software application, data management software, software resource, data analysis software, data processing software, data acquisition software Software which can acquire, analyze, manage, and share mass spectrometry data. MassLynx controls any Waters mass spectrometry system, from sample and solvent management components to mass spectrometer and auxiliary detectors. The software can acquire nominal mass, exact mass, MS/MS and exact mass MS/MS data. The software system also maintains and consolidates all user sample data. Optional Application Manager programs provide additional information for specific MS analyses and data., THIS RESOURCE IS NO LONGER IN SERVICE. Documented on September 16,2025. data acquisition software, data analysis software, data management software, mass spectrometry is listed by: SoftCite THIS RESOURCE IS NO LONGER IN SERVICE SCR_014271 MassLynx MS Software 2026-02-11 10:58:53 5802
I-TASSER
 
Resource Report
Resource Website
1000+ mentions
I-TASSER (RRID:SCR_014627) software resource, software application, data processing software, data analysis software Web server as integrated platform for automated protein structure and function prediction. Used for protein 3D structure prediction. Resource for automated protein structure prediction and structure-based function annotation. Automated prediction, protein structure prediction, protein function prediction, protein 3D structure, amino acid sequence, alignment, simulation, 3D atomic model, protein, bio.tools is listed by: bio.tools
is listed by: Debian
is listed by: SoftCite
has parent organization: University of Michigan; Ann Arbor; USA
has parent organization: University of Kansas; Kansas; USA
NIGMS GM083107;
NIGMS GM084222
DOI:10.1186/1471-2105-9-40
DOI:10.1093/nar/gkv342
PMID:20360767
PMID:18215316
Free, Available for download, Freely available biotools:i-tasser, SCR_018803 https://bio.tools/i-tasser SCR_014627 Iterative Threading Assembly Refinement, Iterative Threading ASSEmbly Refinement 2026-02-11 10:58:59 3702
Cufflinks
 
Resource Report
Resource Website
5000+ mentions
Cufflinks (RRID:SCR_014597) software application, software resource, data analysis software, sequence analysis software, data processing software Software tool for transcriptome assembly and differential expression analysis for RNA-Seq. Includes script called cuffmerge that can be used to merge together several Cufflinks assemblies. It also handles running Cuffcompare as well as automatically filtering a number of transfrags that are likely to be artifacts. If the researcher has a reference GTF file, the researcher can provide it to the script to more effectively merge novel isoforms and maximize overall assembly quality. transcriptome, rna-seq, rna seq, cuffmerge, cufflink, cuffcompare, transfrags, artifacts, gtf file, transcriptome assembly, expression analysis, bio.tools, bio.tools is listed by: Debian
is listed by: bio.tools
is listed by: OMICtools
is listed by: SoftCite
works with: GeneScissors
is hosted by: GitHub
DOI:10.1038/nbt.1621 Acknowledgement requested, Source code available on GitHub biotools:cufflinks, OMICS_01304, SCR_013307 https://github.com/cole-trapnell-lab/cufflinks
https://bio.tools/cufflinks
https://sources.debian.org/src/cufflinks/
SCR_014597 2026-02-11 10:58:58 8838
Minitab
 
Resource Report
Resource Website
5000+ mentions
Minitab (RRID:SCR_014483) software resource, software application, data processing software, data analysis software A statistical software package that allows the user to import data, create graphs, and perform statistical analysis. It can perform basic statistical tests like descriptive statistics, hypothesis tests, confidence intervals, and normality tests as well as regression and ANOVA and quality assessment. data analysis, statistical analysis, hypothesis, confidence, descriptive is listed by: SoftCite SCR_014483 2026-02-11 10:58:55 5778
CVODE
 
Resource Report
Resource Website
50+ mentions
CVODE (RRID:SCR_014696) software resource, software application, data processing software, data analysis software Solver for stiff and nonstiff ordinary differential equation (ODE) systems (initial value problem), given in explicit form y' = f(t,y), based on Adams and BDF methods. It is one of the programs that makes up the Suite of Nonlinear and Differential/Algebraic Equation Solvers (SUNDIALS)., THIS RESOURCE IS NO LONGER IN SERVICE. Documented on September 16,2025. data analysis software, solver, equation solver, ordinary differential equation, differential equation, stiff, nonstiff is listed by: SoftCite THIS RESOURCE IS NO LONGER IN SERVICE SCR_014696 SUNDIALS CVODE 2026-02-11 10:59:12 56
MedCalc
 
Resource Report
Resource Website
10000+ mentions
MedCalc (RRID:SCR_015044) software resource, software application, data processing software, data analysis software Statistical software for ROC curve analysis. MedCalc performs several statistical tests such as method comparison, method evaluation, reference intervals, and meta-analysis. statistic, statistical analysis, roc curve, reference software is listed by: SoftCite Commercially available, Available for purchase, Trial available SCR_015044 2026-02-11 10:59:02 18070
KaleidaGraph
 
Resource Report
Resource Website
1000+ mentions
KaleidaGraph (RRID:SCR_014980) software application, data visualization software, software resource, data analysis software, data processing software Data analysis, graphing, and management application that allows users to import, manipulate, analyze data, and create customized plots. Plots include x-y probability, histogram, box, percentile, horizontal bar, stack bar, column, stack column, polar, and pie. Binned data can be exported to a histogram, step plot, or spike plot. KaleidaGraph works with Windows and Macintosh systems., THIS RESOURCE IS NO LONGER IN SERVICE. Documented on September 16,2025. custom graph, custom plot, publishable graph, publishable plot, data manipulation, curve fitting is listed by: SoftCite THIS RESOURCE IS NO LONGER IN SERVICE SCR_014980 2026-02-11 10:59:02 2788
ClustalW
 
Resource Report
Resource Website
10000+ mentions
ClustalW (RRID:SCR_017277) ClustalW of DDBJ data access protocol, software resource, web service THIS RESOURCE IS NO LONGER IN SERVICE. Documented on September 16,2025.Web sevice of ClustalW provided by DNA data bank of Japan. alignment, service, DNA, data, bank, Japan is listed by: SoftCite THIS RESOURCE IS NO LONGER IN SERVICE SCR_017277 ClustalW of DNA Data Bank of Japan 2026-02-11 10:59:39 10543
Pathway Commons
 
Resource Report
Resource Website
10+ mentions
Pathway Commons (RRID:SCR_002103) PC data or information resource, database, software resource, web service, data access protocol Database of publicly available pathways from multiple organisms and multiple sources represented in a common language. Pathways include biochemical reactions, complex assembly, transport and catalysis events, and physical interactions involving proteins, DNA, RNA, small molecules and complexes. Pathways were downloaded directly from source databases. Each source pathway database has been created differently, some by manual extraction of pathway information from the literature and some by computational prediction. Pathway Commons provides a filtering mechanism to allow the user to view only chosen subsets of information, such as only the manually curated subset. The quality of Pathway Commons pathways is dependent on the quality of the pathways from source databases. Pathway Commons aims to collect and integrate all public pathway data available in standard formats. It currently contains data from nine databases with over 1,668 pathways, 442,182 interactions,414 organisms and will be continually expanded and updated. (April 2013) biological pathway, pathway, molecule, biopax, standard exchange format, bio.tools is listed by: bio.tools
is listed by: Debian
is listed by: SoftCite
is related to: cPath
is related to: Biological General Repository for Interaction Datasets (BioGRID)
is related to: IntAct
is related to: Reactome
is related to: MINT
is related to: HumanCyc: Encyclopedia of Homo sapiens Genes and Metabolism
is related to: Cancer Cell Map
is related to: HPRD - Human Protein Reference Database
is related to: Integrated Molecular Interaction Database
is related to: Pathway Interaction Database
is related to: CHEBI
is related to: UniProt
is related to: PANTHER
is related to: WebGestalt: WEB-based GEne SeT AnaLysis Toolkit
has parent organization: University of Toronto; Ontario; Canada
NHGRI P41HG004118;
NIGMS 2R01GM070743-06;
NIGMS 1T32 GM083937;
Cancer Biomedical Informatics Grid
PMID:21071392 Free, Freely available nif-0000-20884, biotools:PathwayCommons_web_service_API https://bio.tools/PathwayCommons_web_service_API SCR_002103 2026-02-11 10:56:23 14
SAMTOOLS
 
Resource Report
Resource Website
10000+ mentions
SAMTOOLS (RRID:SCR_002105) SAMtools software application, software resource, software toolkit, data analysis software, sequence analysis software, data processing software Original SAMTOOLS package has been split into three separate repositories including Samtools, BCFtools and HTSlib. Samtools for manipulating next generation sequencing data used for reading, writing, editing, indexing,viewing nucleotide alignments in SAM,BAM,CRAM format. BCFtools used for reading, writing BCF2,VCF, gVCF files and calling, filtering, summarising SNP and short indel sequence variants. HTSlib used for reading, writing high throughput sequencing data. Samtools, BCFtools, HTSlib, next generation sequencing, nucleotide alignments, sequence variant, genomic, c, perl, read, alignment, nucleotide, sequence, data, process, sam, bam, cram, vcf, bcf, bio.tools is used by: deFuse
is used by: Short Read Sequence Typing for Bacterial Pathogens
is used by: ROSE
is used by: Fcirc
is listed by: OMICtools
is listed by: Genetic Analysis Software
is listed by: SNVer
is listed by: Debian
is listed by: bio.tools
is listed by: SoftCite
is related to: Platypus
is related to: shovill
is related to: pysam
has parent organization: Wellcome Trust Sanger Institute; Hinxton; United Kingdom
is parent organization of: SAMtools/BCFtools
is required by: RelocaTE
is required by: Wessim
is required by: SL-quant
is required by: smMIPfil
Wellcome Trust ;
NHGRI U54 HG002750
PMID:19505943
PMID:21903627
DOI:10.1093/bioinformatics/btp352
Free, Available for download, Freely available SCR_018682, biotools:samtools, OMICS_01074, nlx_154607, OMICS_00090 https://github.com/samtools/samtools
https://github.com/samtools/htslib
https://bio.tools/samtools
https://sources.debian.org/src/samtools/
http://samtools.sourceforge.net/ SCR_002105 samtools, Samtools, Sequence Alignment Map TOOLS, SAMtools, SAM tools 2026-02-11 10:56:25 30156
Fiji
 
Resource Report
Resource Website
10000+ mentions
Fiji (RRID:SCR_002285) Fiji software application, software resource, source code, data processing software, image processing software Software package as distribution of ImageJ and ImageJ2 together with Java, Java3D and plugins organized into coherent menu structure. Used to assist research in life sciences. imaging, microscopy, windows, linux, java, mac osx, bio.tools uses: Fiji/ImageJ
is used by: MuscleJ
is listed by: Debian
is listed by: bio.tools
is listed by: SoftCite
is related to: ImageJ
is related to: SynapseLocator
is related to: Golddigger
is related to: Analyze Spheroid Cell Invasion In 3D Matrix
has parent organization: Max Planck Institute of Molecular Cell Biology and Genetics; Dresden; Germany
has plug in: BioVoxxel Toolbox
has plug in: imctools
has plug in: Big Data Processor
has plug in: Sholl Analysis
has plug in: SAIBR
has plug in: TWOMBLI
PMID:22743772 Free, Available for download, Freely available, Acknowledgement requested SciRes_000137, biotools:Fiji https://github.com/fiji/fiji
https://bio.tools/Fiji
SCR_002285 Fiji is just ImageJ 2026-02-11 10:56:26 37202
JCB DataViewer
 
Resource Report
Resource Website
10+ mentions
JCB DataViewer (RRID:SCR_002633) JCB DataViewer data repository, data or information resource, database, image repository, service resource, storage service resource THIS RESOURCE IS NO LONGER IN SERVICE. Documented on January 14,2026. A web-based, multi-dimensional image data-viewing application for original microscopy image datasets associated with articles published in The Journal of Cell Biology, a peer-reviewed journal published by The Rockefeller University Press. The JCB DataViewer can host multidimensional fluorescence microscopy images, 3D tomogram data, very large (gigapixel) images, and high content imaging screens. Images are presented in an interactive viewer, and the scores from high content screens are presented in interactive graphs with data points linked to the relevant images. The JCB DataViewer uses the Bio-Formats library to read over 120 different imaging file formats and convert them to the OME-TIFF image data standard. Image data are archived by the Journal and may be freely accessed by readers using the JCB DataViewer. Download of author-provided image data and associated metadata in OME-TIFF format is also possible with author permission, allowing for independent analysis of image data irrespective of acquisition or viewing software. Although the JCB DataViewer is designed to host and facilitate sharing and analysis of original microscopy image data, authors may also upload other types of original image data as supplements to their manuscripts, including histology and electron micrographs and digital scans of gels or blots. microscopy, standardization, data sharing, archiving, data management, metadata standard, visualization, analysis, image collection, histology, electron micrograph, digital scan, gel, blot is listed by: FORCE11
is listed by: SoftCite
is related to: OME-TIFF Format
has parent organization: Rockefeller University; New York; USA
Glencoe Software ;
OME - Open Microscopy Environment
PMID:22869591 THIS RESOURCE IS NO LONGER IN SERVICE nlx_156057, r3d100010895 https://doi.org/10.17616/R3PW4G SCR_002633 2026-02-11 10:56:36 14
BLASTN
 
Resource Report
Resource Website
10000+ mentions
BLASTN (RRID:SCR_001598) BLASTn production service resource, data or information resource, database, data analysis service, service resource, analysis service resource Web application to search nucleotide databases using a nucleotide query. Algorithms: blastn, megablast, discontiguous megablast. nucleotide, alignment, compare, sequence, genome, blast, transcript, dna sequence is listed by: OMICtools
is listed by: SoftCite
has parent organization: NCBI
works with: Seek and Blastn
works with: RMBlast
PMID:17666756
PMID:18567917
Free, Freely available nlx_153932, OMICS_00990 http://blast.ncbi.nlm.nih.gov/Blast.cgi?PROGRAM=blastn&PAGE_TYPE=BlastSearch&LINK_LOC=blasthome SCR_001598 NCBI BLASTN, Nucleotide Blast, Standard Nucleotide BLAST 2026-02-11 10:56:16 19679
Sequencher
 
Resource Report
Resource Website
1000+ mentions
Sequencher (RRID:SCR_001528) Sequencher sequence analysis software software application, software resource, data analysis software, sequence analysis software, data processing software Software for Next-Generation DNA sequencing, Sanger DNA analysis, and RNA sequencing. It contains sequence analysis tools which include reference-guided alignments, de novo assembly, variant calling, and SNP analyses. It has integrated the Cufflinks suite for in-depth transcript analysis and differential gene expression of RNA-Seq data. dna, sequencing, sequence analysis software, NGS, sanger, data visualization is listed by: OMICtools
is listed by: SoftCite
Available for download OMICS_01817 http://genecodes.com/sequencher-features SCR_001528 Sequencher sequence analysis software 2026-02-11 10:56:15 4965
GenABEL
 
Resource Report
Resource Website
500+ mentions
GenABEL (RRID:SCR_001842) software resource, software toolkit, software library THIS RESOURCE IS NO LONGER IN SERVICE. Documented on February 28,2023. R software library for genome-wide association analysis for quantitative, binary and time-till-event traits. r, genome-wide association, single nucleotide polymorphism is listed by: OMICtools
is listed by: Genetic Analysis Software
is listed by: Debian
is listed by: SoftCite
Centre for Medical Systems Biology; Netherlands ;
Netherlands Genomics Initiative ;
Netherlands Organisation for Scientific Research ;
Russian Foundation for Basic Research
PMID:17384015
DOI:10.1186/1471-2105-11-134
DOI:10.1093/bioinformatics/btm108
THIS RESOURCE IS NO LONGER IN SERVICE nlx_154328, OMICS_00234 http://mga.bionet.nsc.ru/~yurii/ABEL/GenABEL/
https://cran.r-project.org/web/packages/GenABEL/index.html
https://sources.debian.org/src/probabel/
SCR_001842 GenABEL package, R/GENABEL 2026-02-11 10:56:19 506
FreeSurfer
 
Resource Report
Resource Website
10000+ mentions
FreeSurfer (RRID:SCR_001847) FreeSurfer software application, image analysis software, data visualization software, software resource, data processing software Open source software suite for processing and analyzing human brain MRI images. Used for reconstruction of brain cortical surface from structural MRI data, and overlay of functional MRI data onto reconstructed surface. Contains automatic structural imaging stream for processing cross sectional and longitudinal data. Provides anatomical analysis tools, including: representation of cortical surface between white and gray matter, representation of the pial surface, segmentation of white matter from rest of brain, skull stripping, B1 bias field correction, nonlinear registration of cortical surface of individual with stereotaxic atlas, labeling of regions of cortical surface, statistical analysis of group morphometry differences, and labeling of subcortical brain structures.Operating System: Linux, macOS. processing, analysis, human, brain, MRI, image, reconstruction, cortical, surface, fMRI, data is used by: Wisconsin Cortical Thickness Analysis (CTA) Toolbox
is used by: freesurfR
is used by: Automatic Analysis
is used by: NHP Freesurfer
is listed by: NeuroImaging Tools and Resources Collaboratory (NITRC)
is listed by: Biositemaps
is listed by: Debian
is listed by: SoftCite
is related to: PySurfer
is related to: RFT FDR
is related to: FMRLAB
is related to: TRACULA
is related to: BASH4RfMRI
has parent organization: Harvard University; Cambridge; United States
has plug in: JOSA
works with: NIAG Addiction Data
NCRR U24 RR021382;
NINDS R01 NS052585;
NCRR RR014075
PMID:22248573 Free, Available for download, Freely available nif-0000-00304 https://sources.debian.org/src/freesurfer/
http://www.nitrc.org/projects/freesurfer
http://surfer.nmr.mgh.harvard.edu/fswiki/DownloadAndInstall
SCR_001847 2026-02-11 10:56:20 11817
PLINK
 
Resource Report
Resource Website
10000+ mentions
Issue
PLINK (RRID:SCR_001757) software application, software resource, software toolkit, data analysis software, data processing software Open source whole genome association analysis toolset, designed to perform range of basic, large scale analyses in computationally efficient manner. Used for analysis of genotype/phenotype data. Through integration with gPLINK and Haploview, there is some support for subsequent visualization, annotation and storage of results. PLINK 1.9 is improved and second generation of the software. gene, genetic, genomic, genotype, phenotype, copy number variant, whole-genome association, population, linkage analysis, whole-genome association study, data management, summary statistics, population stratification, association analysis, identity-by-descent estimation is listed by: OMICtools
is listed by: Genetic Analysis Software
is listed by: NeuroImaging Tools and Resources Collaboratory (NITRC)
is listed by: Debian
is listed by: SoftCite
is related to: Whap
is related to: PLINK/SEQ
is related to: Haploview
is related to: MendelIHT.jl
PMID:17701901
DOI:10.1086/519795
Free, Available for download, Freely Available nlx_154200, OMICS_00206, SCR_021271 https://zzz.bwh.harvard.edu/plink/
https://www.cog-genomics.org/plink/1.9/general_usage#cite
https://sources.debian.org/src/plink/
http://pngu.mgh.harvard.edu/~purcell/plink/ SCR_001757 PLINK 1.9, PLINK/SEQ, plink - Whole genome association analysis toolset 2026-02-11 10:56:18 15344

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