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SciCrunch Registry is a curated repository of scientific resources, with a focus on biomedical resources, including tools, databases, and core facilities - visit SciCrunch to register your resource.
http://uccaribe.eagle-i.net/i/00000136-ad2d-0008-a53f-a15a80000000
Core facility that provides the following services: Free movement behavioral testing data acquisition and analysis service, Small animal vital sign evaluation. The Behavioral Testing Facility was created to facilitate the development of neuroscience research at the Universidad Central del Caribe recognizing the importance of behavioral testing. The facility has two mayor components: A) the equipment infrastructure and B) the technical support division. The facility offers equipment for remote behavior visualization (RBV).
Proper citation: UCC Behavioral Testing Facility (RRID:SCR_010072) Copy
http://uccaribe.eagle-i.net/i/00000135-c95d-a6f3-a272-8ee780000000
THIS RESOURCE IS NO LONGER IN SERVICE. Documented on January 26,2026. Core facility that provides the following services: Research support, Research Training. The DMSRSU provides study design, data management, quality assurance, and statistical analysis support for UCC researchers. The DMSRSU has a strong infrastructure which includes the following subunits: Data Abstraction and Management; Data Entry; Quality Control; Data Analysis and Consultant; and Administrative and Computer Systems. Each of these subunits consists of experienced professionals readily available to assist researchers and to provide data management and statistical research support to investigators. In addition, the DMSRSU counts on a highly experienced and reliable consulting team.
Proper citation: UCC Data Management and Statistical Research Support Unit (RRID:SCR_010074) Copy
http://hawaii.eagle-i.net/i/0000012a-2510-c9ec-c99c-aef680000000
Core facility that provides the following services: Cell cycle analysis with live or dead cells, Apoptosis analysis service, Calcium flux analysis service, Cell population isolation service. The of the goal of the Immunology Core of MCI, which functions as a fee-for-service facility, is to provide the Hawaii community with a service-oriented facility to meet the needs in the FACS research areas. We are equipped with BD FACSAria, BD FACSCalibur, GuavaEAsyCytePlus, Luminex 200, Beckman-Coulter ViCell, CTL-ImmunoSpot�� S5 Core Analyzer, Bio-Rad and BioTek ELx808 ELISA readers and washers, Faxitron compact 43855D x-ray irradiation system, and Faxitron x-ray CP160 for in vivo animal work.
Proper citation: UH Manoa COBRE Molecular and Cellular Immunology Core (RRID:SCR_010075) Copy
http://hawaii.eagle-i.net/i/0000012a-2511-e8d3-c99c-aef680000000
Our core provides a standardized library of pathogens and reagent materials.
Proper citation: UH Manoa RCMI Pathogen Reference and Reagent Core (RRID:SCR_010110) Copy
http://hawaii.eagle-i.net/i/0000012b-3598-9562-2f73-b43980000000
ESF project support comes under four categories: # New Funded Grants: The ESF supports researchers in planning proposals that will utilize ESF capabilities. For funded grants, the support should ideally begin at the early proposal stage. In consultation with the researcher, ESF can suggest practical and creative ways of obtaining and recording the desired data. # Support for Ongoing Funded Programs: The Engineering Support Facility has personnel and experience to repair and maintain laboratory instruments and equipment. In some cases, the existing laboratory instruments need some custom enhancements or adaptations for the particular science in view. ESF has experience going back over 35 years in custom modifications and enhancements to existing instruments. # Machine Shop: The ESF has a well-equipped machine shop and an expert instrument maker. # Pressure Test Facilities: The ESF operates a hydraulic pressure test vessel that can test pressure cases from 15 to 10,000 psia, with electronic feed-thru capability. The test vessel can accommodate objects up to 30 inches in outside diameter by 13 feet length.
Proper citation: UH Manoa SOEST Engineering Support Facility (RRID:SCR_010112) Copy
http://alaska.eagle-i.net/i/0000012a-2507-5cac-a68e-378080000000
Core facility that provides the following services: Data quality control and management service. The Nutrition and Physical Activity Core supports multidisciplinary research requiring dietary and/or physical activity assessment, as well as provide nutritional sciences expertise. The NPA Core offers a range of services including high-quality dietary assessment, active collaboration in the design, implementation, and analysis of nutrition-related research. In addition to supporting the needs of CAHNR projects, the NPA Core will also actively promote and foster new research programs investigating the diet of Alaska Natives.
Proper citation: UAF Nutrition and Physical Activity Core (RRID:SCR_010070) Copy
http://alaska.eagle-i.net/i/0000012a-2507-70de-a68e-378080000000
The primary research of the laboratory aims at understanding the role of Rho-subfamily small GTPases, in particular Rac1A, as pivotal regulators of actin filament dynamics and redox homeostasis in central nervous system (CNS) neurons. A second project addresses neuronal stem cells and their generation, functional integration, and elimination in the adult male wild songbird Junco hyemalis.
Proper citation: UAF Optical and Tissue Culture Core (RRID:SCR_010071) Copy
http://hawaii.eagle-i.net/i/0000012a-2512-c48e-c99c-aef680000000
Core facility that provides the following services: Cell cycle analysis with live or dead cells, Cell cycle analysis service, Fluorescent cell (particle) analysis, Fluorescent cell (particle) sorting service. The Flow Cytometry Facility, operated out of the School for Ocean, Earth Sciences and Technology at the University of Hawaii, provides state of the art instrumentation for analyzing and sorting particles. Flow cytometers detect particles based on their size (scatter) and fluorescence (auto or imparted by a dye). These particles can be enumerated or simply characterized as to their scatter and fluorescence characteristics. Multiple populations can be separated visually and if desired, physically, based on these properties. Flow cytometers work ideally with cells in the 0.2 - 200 ��m diameter size range and cell concentrations as low as 1000 cells/ml.
Proper citation: UH Manoa SOEST Flow Cytometry Facility (RRID:SCR_010113) Copy
http://upr.eagle-i.net/i/0000012b-d046-33f8-8054-a41680000000
Core facility that provides the following services: Molecular biology services. The FGRc of the UPR is the only facility of its kind in Puerto Rico and the Caribbean. The unique infrastructure of the FGRc positions it to be the provider of expertise and services related to functional genomics research to academia, government and industry in Puerto Rico and abroad, all within one unique center.
Proper citation: UPR AABRE Program: Functional Genomics Research Center (RRID:SCR_010115) Copy
http://upr.eagle-i.net/i/0000012b-00c0-a5a2-9e37-5ded80000000
Core facility that provides the following services: Genotyping analysis service, Microarray service. The lab has the following general goals: 1. To strengthen the scientific interactions between basic scientists and clinicians from the MSC and to enhance collaborations with international scientists working in molecular biology, human genetics, and infectious diseases; 2. To provide training, education, and support for the development of young scientists as well as established basic and clinical researchers with participation of internationally recognized leaders in the field; 3. To establish a centralized DNA, plasma and cell banking facility for storage of clinical samples from human blood or skin biopsies; 4. To provide basic services in molecular biology and human genetics; and 5. To initiate webcasting of training sessions in specialized areas in collaboration with the Center for Information Architecture in Research.
Proper citation: UPR AABRE Program: Human Genetics Center (RRID:SCR_010116) Copy
http://upr.eagle-i.net/i/0000012b-00be-be94-9e37-5ded80000000
Core facility that provides the following services: Training opportunities for protein analysis. The lab consists of materials and equipment for the identification and/or analysis of protein samples by electrospray LC/MS/MS.
Proper citation: UPR AABRE Program: Protein Mass Spectrometry Facility (RRID:SCR_010117) Copy
http://hawaii.eagle-i.net/i/0000012b-36b7-8cc7-2f73-b43980000000
Core facility that provides the following services: ELISA-based assay service, Luminex based ELISA assay service, Coenzyme Q10 in plasma analysis by HPLC/ECD (oxidized, reduced and total Q10), DNA analysis by HPLC, Phenolic agents from plasma, urine, breast milk, foods analysis by LC/MSMS, Lipid-phase micronutrients in plasma or foods analysis by HPLC/PDA/FD (12 carotenoids, 2 retinoids, 3 tocopherols), Metabolomics analysis by LCMS, Vitamin A and pro-vitamin A in plasma analysis by HPLC/PDA, Vitamin C in plasma, food analysis by HPLC/ECD or PDA, Vitamin D in plasma analysis by LC/MSMS, Vitamin E in plasma analysis by NP-HPLC/PDA/FD (all tocopherols), Vitamin K analysis by LC/MSMS. The Analytical Biochemistry resource was established to support and facilitate collaborative cancer research between the various disciplines at the Center by providing chemical analyses which contribute to understanding chronic diseases in our population. It also assists in the determination of the nature or structure of biological molecules as well as the quantification of those compounds. The facility is equipped with essential instruments needed to perform analytical chemistry, and modern, state-of-the-art technology for difficult-to-measure and ultra-low concentrated compounds.
Proper citation: UH Manoa Analytical Biochemistry Shared Resource (RRID:SCR_010085) Copy
http://upr.eagle-i.net/i/0000012c-54be-d3f6-5b95-f21080000000
The CDIR serves as the focal point for drug information, research, education, and service within the University of Puerto Rico - School of Pharmacy. The CDIR is the first academic-based research center in Puerto Rico solely dedicated to provide answers to drug related information inquires, health service research support consultations, and the development, implementation and evaluation of pharmacy educational programs. The mission of the CDIR is to improve drug therapy in Puerto Rico through drug information services, and educational, clinical and novel research initiatives.
Proper citation: UPR Center for Drug Information and Research (RRID:SCR_010121) Copy
http://upr.eagle-i.net/i/0000012f-96f8-a528-f2e2-7b7e80000000
THIS RESOURCE IS NO LONGER IN SERVICE. Documented on January 26,2026. The overall goal of the Center for Information Technologies and Telecommunications (CentIT2) is to provide specialized information technology services to support research, professional development and global interactions at the University of Puerto Rico Medical Sciences Campus. Collaboration from other information technology units from the University of Puerto Rico Medical Sciences Campus (MSC) and from the University of Puerto Rico (UPR) System has been secured to provide access to their unique assets when necessary, avoiding duplication of resources.
Proper citation: UPR Center for Information Technologies and Telecommunications (RRID:SCR_010123) Copy
http://uccaribe.eagle-i.net/i/00000137-035f-9eba-a53f-a15a80000000
Core facility that provides the following services: Image acquisition training. The TEM laboratory provides access to ultrastructural analysis of biological specimens via a Jeol 100 CX transmission electron microscope. The TEM is equipped with AMT 4 MP digital camera to facilitate image acquisition and 3D reconstruction from serial sections. In addition, to conventional EM procedures of in situ and cell culture specimens the laboratory also offers imunnogold labeling and the visualization of fluorescent dyes after photoconversion.
Proper citation: UCC Transmission Electron Microscopy Laboratory (RRID:SCR_010081) Copy
https://wistar.org/research-discoveries/shared-resources/bioinformatics-facility
Core provides High Throughput Data Analysis, Customized Bioinformatics Services, Custom Programming, High Performance Computing, Data management. Located in the Center for Systems and Computational Biology. Provides Cancer Center investigators with database management, software application support, expertise in statistical analyses and computational modeling of biomedical research data.
Proper citation: Wistar Bioinformatics Core Facility (RRID:SCR_010203) Copy
http://eagle-i.itmat.upenn.edu/i/0000013f-8b15-e20f-a468-831a80000000
THIS RESOURCE IS NO LONGER IN SERVICE. Documented on May 22,2024.Core facility that provides the following services: Tissue culture suite access, Biological assay development for screening experiments, High-throughput-screening service, Post-screening studies. The Wistar Molecular Screening Facility is a shared resource facility open to Wistar and non-Wistar scientists. The laboratory operates on a fee-for-service basis, providing expertise in bridging automated technology with the development of innovative, robust biochemical or cell-based assays for high-throughput chemical and functional genomic screens. The laboratory strives to possess the flexibility to accommodate diverse biological systems and a variety of investigator-developed assay types. While service is the primary role of the laboratory, the staff will also develop and implement new technology as needed to fulfill the needs of its users. Education and training is also part of the laboratory''s mission, as trainees apply high-throughput screening experiments to their investigations. The ultimate goal of the laboratory is to enable scientists to apply cutting edge technology and unique resources to discover agents (i.e. small molecules, siRNA) to further study the functions of poorly understood proteins, signaling pathways, and cells in complex biological process relevant to human physiology and disease. The combinations of these activities will provide scientists opportunities to develop new innovative basic and translational research, preliminary data for hypothesis driven research grant applications, and public-private partnerships. The Wistar Molecular Screening Facility was developed with support from the Lankenau Institute for Medical Research, the Commonwealth of Pennsylvania Department of Community and Economic Development Keystone Innovation Zone initiative, The F. M. Kirby Foundation, The CLAWS Foundation, The Florence & Daniel Green Foundation, The McClean Contributionship, From The Heart Foundation, and the Noreen O?Neill Foundation for Melanoma Research.
Proper citation: Wistar Molecular Screening Facility (RRID:SCR_010208) Copy
http://eagle-i.ea.vanderbilt.edu/i/00000138-7bdf-33f8-480b-864680000000
This core has several components. The DNA bank receives specimens from various studies, extracts DNA, and provides storage. Quality control, organization, and efficiency are critical. Genotyping services provide the necessary speed, efficiency, and accuracy to perform genomic screens (with standard markers) in as little time as possible.
Proper citation: Vanderbilt DNA Resources Core (RRID:SCR_010176) Copy
http://eagle-i.itmat.upenn.edu/i/0000013f-8bde-1d59-a468-831a80000000
THIS RESOURCE IS NO LONGER IN SERVICE. Documented on May 22,2024.Core facility that provides the following services: Recombinant plasmid DNA engineering, Recombinant protein production via Baculovirus expression systems (BVES), Recombinant protein production in prokaryotic systems, Recombinant protein purification, Retrovirus production service. The Protein Expression Facility is a shared resource laboratory that provides Wistar Cancer Center Members and non-Wistar scientists technical assistance with viral vector preparation and the expression and purification of recombinant proteins. The Facility has greater than 20 years of experience in recombinant protein expression with special expertise in the use of baculovirus expression systems (BVES). The Facility offers the following services: 1. Recombinant plasmid DNA engineering 2. Viral vector production (i.e. baculovirus and retrovirus) 3. Analytical and preparative scale expression of nascent or epitope-tagged recombinant proteins 4. Protein purification These goals are accomplished by a centralized laboratory with dedicated, experienced staff, which enables high-throughput, economy of scale, virus preparation and protein expression services, including quality assurance and control procedures to ensure efficient, consistent production and purification of recombinant proteins and viral vectors. Many recombinant proteins produced by the facility have been used for crystallization efforts, analytical biochemistry studies designed to investigate enzymatic properties, structure-function relationships between protein-protein, protein-nucleic-acid, and protein-small molecule interactions, custom antibody production, experimental cancer vaccines, and development of miniaturized assays for small molecule screening. The facility is supported in part by an NCI Cancer Center Support Grant and a grant from the NIH National Institute of Aging (PO1 AG031862).
Proper citation: Wistar Protein Expression Facility (RRID:SCR_010210) Copy
https://www.wistar.org/resources/proteomics-metabolomics-facility/
Core facility that provides the following services: In-gel protease digestion service, LC-MS/MS protein identification service, Gel/LC-MS/MS Comprehensive analysis of a subproteome or proteome, MudPIT (LC/LC-MS/MS) analyis?comprehensive analysis of a subproteome or proteome, Reverse phase microbore HPLC peptide mapping service, MALDI mass spectrometry, ESI of intact proteins, Post-translational modification identifications, Custom proteomics database creation, Custom proteomics data analysis, Proteomics methods development. The Wistar Proteomics Facility provides mass spectrometry (MS) and sequence analysis of proteins and peptides at maximum sensitivity using state-of-the-art instruments and methods. The most commonly used services are identifications of either purified proteins or complex protein mixtures, such as sub-proteomes or complete proteomes, using electrospray ionization tandem mass spectrometry (ESI MS/MS). Typically, either individual bands are excised from 1-D SDS gels, or the entire gel lane is analyzed by slicing it into uniform fractions followed by trypsin digestion and nanocapillary HPLC interfaced directly with hybrid ion trap mass spectrometry (Gel/LC-MS/MS). Data is analyzed and filtered to produce low false-positive rates. Several options are available for quantitatively comparing protein changes in related samples, and additional options will be implemented in the future. Complementary services include reverse-phase microbore HPLC peptide mapping with UV detection and mass measurements of intact peptides and proteins using MALDI MS or ESI MS. Posttranslational modification (PTM) analyses including identifications of specific modified residues also are provided, although investigators should recognize that in most cases these studies are quite complex and require substantial effort. These studies, as well as analyses of complex protein mixtures, usually require preparation of custom sequence databases and/or custom data analyses, which can be provided by the facility as needed.
Proper citation: Wistar Proteomics and Metabolomics Core Facility (RRID:SCR_010211) Copy
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