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SciCrunch Registry is a curated repository of scientific resources, with a focus on biomedical resources, including tools, databases, and core facilities - visit SciCrunch to register your resource.

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Resource Name Proper Citation Abbreviations Resource Type Description Keywords Resource Relationships Related Condition Funding Defining Citation Availability Website Status Alternate IDs Alternate URLs Old URLs Parent Organization Resource ID Synonyms Record Last Update Mentions Count
GEN3VA
 
Resource Report
Resource Website
1+ mentions
GEN3VA (RRID:SCR_015682) software resource, software application, data analysis software, data processing software Software tool for aggregation and analysis of gene expression signatures from related studies.Used to aggregate and analyze gene expression signatures extracted from GEO by crowd using GEO2Enrichr. Used to view aggregated report that provides global, interactive views, including enrichment analyses, for collections of signatures from multiple studies sharing biological theme. GEO2Enrichr, gene expression signatures, enrichment analyses, multiple studies, biological theme, bio.tools is listed by: bio.tools
is listed by: Debian
works with: Gene Expression Omnibus (GEO)
NHLBI U54 HL127624;
NCI U54 CA189201;
NIGMS R01 GM098316
PMID:27846806 Free, Freely available biotools:gen3va https://github.com/MaayanLab/gen3va
https://bio.tools/gen3va
SCR_015682 GENE Expression and Enrichment Vector Analyzer 2026-02-12 09:46:19 5
CRowd Extracted Expression of Differential Signatures
 
Resource Report
Resource Website
1+ mentions
CRowd Extracted Expression of Differential Signatures (RRID:SCR_015680) CREEDS software resource, web application, database, software application, data processing software, data or information resource, data visualization software Software resource that allows students or the general public find variants that may be significantly associated with some disease. CREEDS also visualizes and analyzes gene expression signatures. variant, disease expression, disease marker NIGMS R01GM098316;
NHLBI U54HL127624;
NCI U54CA189201
PMID:27667448 Freely available, Free, Available for download SCR_015680 CREEDS: CRowd Extracted Expression of Differential Signatures 2026-02-12 09:46:36 3
L1000 Characteristic Direction Signature Search Engine
 
Resource Report
Resource Website
1+ mentions
L1000 Characteristic Direction Signature Search Engine (RRID:SCR_016177) L1000CDS2 data access protocol, software resource, service resource, web service, database, data or information resource, data set LINCS L1000 characteristic direction signatures search engine. Software tool to find consensus signatures that match user’s input gene lists or input signatures. Underlying dataset is LINCS L1000 small molecule expression profiles generated at Broad Institute by Connectivity Map team. Differentially expressed genes of these profiles were calculated using multivariate method called Characteristic Direction. signature, gene, dataset, ligand, characteristic, expression, benchmark is related to: LINCS Joint Project - Breast Cancer Network Browser
has parent organization: Icahn School of Medicine at Mount Sinai; New York; USA
NHLBI U54 HL127624;
NCI U54 CA189201
PMID:28413689 Free, Freely available SCR_016177 2026-02-12 09:46:44 8
Harmonizome
 
Resource Report
Resource Website
100+ mentions
Harmonizome (RRID:SCR_016176) software resource, web application, database, software application, data processing software, data or information resource, data visualization software Web application that allows for searching, visualization, and prediction about genes and proteins. It contains a collection of processed datasets gathered to serve and mine knowledge about genes and proteins from major online resources. gene, protein, visualization, search, prediction, functional BD2K-LINCS Data Coordination and Integration Center ;
Illuminating the Druggable Genome ;
Knowledge Management Center ;
NIGMS R01 GM098316;
NHLBI U54 HL127624;
NCI U54 CA189201
PMID:27374120 Freely available, Free, Available for download SCR_016176 2026-02-12 09:46:26 127
BioJS
 
Resource Report
Resource Website
10+ mentions
BioJS (RRID:SCR_003119) BioJS software toolkit, software resource, software application, data processing software, software library, data visualization software An open source JavaScript library of components for visualisation of biological data on the web. javascript, bio.tools is listed by: bio.tools
is listed by: Debian
has parent organization: The Genome Analysis Centre; Norwich; United Kingdom
has parent organization: European Bioinformatics Institute
BBSRC ;
NHLBI HHSN268201000035C;
European Union PSIMEx FP7-HEALTH-2007-223411
PMID:23435069 Free, Freely available biotools:biojs, nlx_156742 http://www.ebi.ac.uk/Tools/biojs/registry/
https://bio.tools/biojs
http://www.tgac.ac.uk/tools-resources/biojs/ SCR_003119 2026-02-12 09:43:31 22
MAPPFinder
 
Resource Report
Resource Website
10+ mentions
MAPPFinder (RRID:SCR_005791) MAPPFinder software resource, software application, data analysis software, data processing software MAPPFinder is an accessory program for GenMAPP. This program allows users to query any existing GenMAPP Expression Dataset Criterion against GO gene associations and GenMAPP MAPPs (microarray pathway profiles). The resulting analysis provides the user with results that can be viewed directly upon the Gene Ontology hierarchy and within GenMAPP, by selecting terms or MAPPs of interest. Platform: Windows compatible gene, gene ontology, gene association, gene expression, profile, microarray, pathway, statistical analysis is listed by: Gene Ontology Tools
is related to: Gene Ontology
has parent organization: University of California at San Francisco; California; USA
has parent organization: Gene Map Annotator and Pathway Profiler
University of California at San Francisco; California; USA ;
San Francisco General Hospital; California; USA ;
NHLBI ;
NCRR MO1RR00083
PMID:12540299 Free for academic use nlx_149270 SCR_005791 2026-02-12 09:44:10 26
Phenotypes and eXposures Toolkit
 
Resource Report
Resource Website
50+ mentions
Phenotypes and eXposures Toolkit (RRID:SCR_006532) PhenX Toolkit data set, standard specification, service resource, database, narrative resource, data or information resource, catalog Set of measures intended for use in large-scale genomic studies. Facilitate replication and validation across studies. Includes links to standards and resources in effort to facilitate data harmonization to legacy data. Measurement protocols that address wide range of research domains. Information about each protocol to ensure consistent data collection.Collections of protocols that add depth to Toolkit in specific areas.Tools to help investigators implement measurement protocols. PhenX project, genome, phenotype, genome-wide association study, genetic variation, genomic study, substance abuse, addiction, substance use, environmental exposure, disease susceptibility, outcome, bio.tools is listed by: bio.tools
is listed by: Debian
has parent organization: RTI International
has parent organization: Consensus Measures for Phenotype and Exposure
has parent organization: Trans-Omics for Precision Medicine (TOPMed) Program
has organization facet: PhenX Phenotypic Terms
is organization facet of: Consensus Measures for Phenotype and Exposure
NHGRI U01 HG004597;
NHGRI U41HG007050;
NIDA ;
OBSSR ;
NIMH ;
NHLBI ;
NIMHD ;
TRSP ;
NHGRI U24 HG012556;
ODP ;
NINDS ;
NCI
PMID:21749974 Restricted SCR_017475, biotools:PhenX_toolkit, nlx_144102 https://bio.tools/PhenX_Toolkit SCR_006532 Phenotypes and eXposures Toolkit 2026-02-12 09:44:25 61
Rat Genome Database (RGD)
 
Resource Report
Resource Website
100+ mentions
Rat Genome Database (RGD) (RRID:SCR_006444) RGD data repository, service resource, storage service resource, database, data or information resource Database for genetic, genomic, phenotype, and disease data generated from rat research. Centralized database that collects, manages, and distributes data generated from rat genetic and genomic research and makes these data available to scientific community. Curation of mapped positions for quantitative trait loci, known mutations and other phenotypic data is provided. Facilitates investigators research efforts by providing tools to search, mine, and analyze this data. Strain reports include description of strain origin, disease, phenotype, genetics, immunology, behavior with links to related genes, QTLs, sub-strains, and strain sources. RIN, Resource Information Network, mouse, rat, human, gene, qtl, marker, map, strain, sequence, est, genome, ontology, pathway, comparative genomics, physiology, phenotype, disease, model organism, proteomics, function, genetic, genomic, variation, immunology, behavior, knockout, inbred rat strain, mutant, congenic rat, recombinant inbred rat, data analysis service, organism supplier, genotype, gold standard, FASEB list, RRID Community Authority uses: InterMOD
is used by: ChannelPedia
is used by: Resource Identification Portal
is used by: DisGeNET
is used by: Integrated Animals
is used by: NIH Heal Project
is recommended by: Resource Identification Portal
is listed by: re3data.org
is listed by: InterMOD
is listed by: Resource Information Network
is affiliated with: InterMOD
is related to: Rat Gene Symbol Tracker
is related to: MPO
is related to: NIF Data Federation
is related to: MONARCH Initiative
is related to: Vertebrate Trait Ontology
is related to: Biositemaps
is related to: One Mind Biospecimen Bank Listing
is related to: AmiGO
is related to: OMICtools
is related to: re3data.org
is related to: Integrated Manually Extracted Annotation
is related to: OntoMate
has parent organization: Medical College of Wisconsin; Wisconsin; USA
is parent organization of: Diabetes Disease Portal
is parent organization of: Rat Strain Ontology
is parent organization of: Rat Strain Ontology
is parent organization of: Renal Disease Portal
NHLBI PMID:23434633
PMID:18996890
PMID:17151068
Free, Freely available nif-0000-00134, r3d100010417, OMICS_01660 https://doi.org/10.17616/R3WK60 SCR_006444 , Rat Genome Database, RGD 2026-02-12 09:44:21 272
VISTA Browser
 
Resource Report
Resource Website
50+ mentions
VISTA Browser (RRID:SCR_011808) software toolkit, software resource Software tools for comparative genomics.Comprehensive suite of programs and databases for comparative analysis of genomic sequences. There are two ways of using VISTA - you can submit your own sequences and alignments for analysis (VISTA servers) or examine pre-computed whole-genome alignments of different species. Comparative genomics tools, genomic sequences, comparative analysis, bio.tools, FASEB list is listed by: OMICtools
is listed by: Debian
is listed by: bio.tools
has parent organization: Lawrence Berkeley National Laboratory
Office of Biological and Environmental Research ;
Office of Science ;
US Department of Energy ;
NHLBI
PMID:15215394 Free, Freely available OMICS_00948, biotools:vista http://genome.lbl.gov/vista/index.shtml
https://bio.tools/vista
SCR_011808 VISTA, vista 2026-02-12 09:45:20 87
Eagle
 
Resource Report
Resource Website
50+ mentions
Eagle (RRID:SCR_015991) software toolkit, software resource Software package for statistical estimation of haplotype phase either within a genotyped cohort or using a phased reference panel in large scale sequencing. The package includes Eagle1 (to harness identity-by-descent among distant relatives to rapidly call phase using a fast scoring approach) and Eagle2 (to analyze a full probabilistic model similar to the diploid Li-Stephens model used by previous HMM-based methods. hmm, hidden markov model, statistic, estimation, haplotype, phase, reference, panel, sequencing, algorithm, analysis, probability is listed by: Debian
is listed by: OMICtools
has parent organization: Broad Institute
NHGRI R01 HG006399;
NIMH R01 MH101244;
NHGRI F32HG007805;
Wellcome Trust WT098051;
Austrian Science Fund J-3401;
NHGRI HG007022;
NHLBI HL117626;
Fannie and John Hertz Foundation ;
NCRR S10 RR028832;
NWO 480-05-003;
Dutch Brain Foundation
PMID:27694958
PMID:27270109
Free, Available for download, Freely available OMICS_14099, SCR_017262 https://sources.debian.org/src/bio-eagle/
https://github.com/poruloh/Eagle
https://data.broadinstitute.org/alkesgroup/Eagle/downloads/
SCR_015991 Bio-eagle, Eagle1, Eagle2 2026-02-12 09:46:15 51
SingleR
 
Resource Report
Resource Website
100+ mentions
SingleR (RRID:SCR_023120) software toolkit, software resource Software R package for unbiased cell type recognition of scRNA-seq data. Performs unbiased cell type recognition from single-cell RNA sequencing data, by leveraging reference transcriptomic datasets of pure cell types to infer cell of origin of each single cell independently. unbiased cell type recognition, scRNA-seq data, reference transcriptomic datasets, pure cell types, infer cell of origin UCSF Marcus Award ;
NHLBI HL131560;
UCSF Nina Ireland Program award ;
NHLBI HL139897;
NIAID
PMID:30643263 Free, Available for download, Freely available https://github.com/dviraran/SingleR
https://github.com/LTLA/SingleR
SCR_023120 Single-cell RNA-seq cell types Recognition 2026-02-12 09:47:34 321
MR-PRESSO
 
Resource Report
Resource Website
50+ mentions
MR-PRESSO (RRID:SCR_023697) software toolkit, software resource Software R package for performing Mendelian randomization pleiotropy residual sum and outlier method.Used to identify horizontal pleiotropic outliers in multi instrument summary level MR testing. Mendelian randomization, identify horizontal pleiotropic outliers, multi instrument summary level MR testing, NIGMS R35 GM124836;
NHLBI R01 HL139865;
AstraZeneca ;
Goldfinch Bio ;
American Heart Association Cardiovascular Genome Phenome Discovery ;
NIMH 1R01 MH094469;
NIMH 1R01 MH107649;
NHGRI 5U01 HG009088
PMID:29686387 Free, Available for download, Freely available SCR_023697 Mendelian Randomization Pleiotropy RESidual Sum and Outlier 2026-02-12 09:47:59 64
FuncAssociate: The Gene Set Functionator
 
Resource Report
Resource Website
10+ mentions
FuncAssociate: The Gene Set Functionator (RRID:SCR_005768) FuncAssociate service resource, analysis service resource, production service resource, data analysis service A web-based tool that accepts as input a list of genes, and returns a list of GO attributes that are over- (or under-) represented among the genes in the input list. Only those over- (or under-) representations that are statistically significant, after correcting for multiple hypotheses testing, are reported. Currently 37 organisms are supported. In addition to the input list of genes, users may specify a) whether this list should be regarded as ordered or unordered; b) the universe of genes to be considered by FuncAssociate; c) whether to report over-, or under-represented attributes, or both; and d) the p-value cutoff. A new version of FuncAssociate supports a wider range of naming schemes for input genes, and uses more frequently updated GO associations. However, some features of the original version, such as sorting by LOD or the option to see the gene-attribute table, are not yet implemented. Platform: Online tool gene, gene ontology, statistical analysis, web service, bio.tools is listed by: Gene Ontology Tools
is listed by: OMICtools
is listed by: bio.tools
is listed by: Debian
is related to: Gene Ontology
has parent organization: Roth Laboratory
NIH ;
Canadian Institute for Advanced Research ;
NINDS NS054052;
NINDS NS035611;
NHLBI HL081341;
NHGRI HG0017115;
NHGRI HG004233;
NHGRI HG003224
PMID:19717575
PMID:14668247
Free for academic use, Acknowledgement requested biotools:funcassociate, OMICS_02264, nlx_149233 http://llama.mshri.on.ca/cgi/func/funcassociate
https://bio.tools/funcassociate
SCR_005768 2026-02-12 09:44:16 36
CRAPome
 
Resource Report
Resource Website
10+ mentions
CRAPome (RRID:SCR_025008) data access protocol, software resource, web service, database, data or information resource Database of Mass Spectrometry contaminants and pipeline for Affinity Purification coupled with Mass Spectrometry analysis. Contaminant repository for affinity purification mass spectrometry data. Database of standardized negative controls. Used to identify protein-protein interactions. Mass Spectrometry contaminants, standardized negative controls, contaminant repository, AP-MS analysis, affinity purification, mass spectrometry data, NIGMS 5R01GM94231;
NIDA DP1DA026192;
NHLBI HL112618-01;
Canadian Institutes of Health Research ;
government of Ontario ;
Austrian Academy of Sciences ;
Austrian Federal Ministry for Science and Research ;
European Research Council ;
Austrian Science Fund ;
European Molecular Biology Organisation ;
Netherlands Proteomics Center ;
European Union 7th Framework Program ;
Stowers Institute for Medical Research ;
Human Frontier Science Program ;
NCI R21 CA16006001A1
PMID:23921808 Free, Freely available, https://reprint-apms.org/ SCR_025008 CRAPome:Contaminant Repository for Affinity Purification 2026-02-12 09:48:10 16
drug perturbation Gene Set Enrichment Analysis
 
Resource Report
Resource Website
1+ mentions
drug perturbation Gene Set Enrichment Analysis (RRID:SCR_025351) dpGSEA source code, software resource Software tool to detect phenotypically relevant drug targets through unique transcriptomic enrichment that emphasizes biological directionality of drug-derived gene sets. Exploratory tool to screen for possible drug targeting molecules. detect phenotypically relevant drug targets, drug-derived gene sets, transcriptomic enrichment, NHLBI T32HL007567;
NIAID P30AI036219
DOI:10.1186/s12859-020-03929-0 Free, Available for download, Freely available SCR_025351 2026-02-12 09:48:23 1
TooManyCells
 
Resource Report
Resource Website
1+ mentions
TooManyCells (RRID:SCR_025328) source code, software resource, software toolkit Software suite of tools, algorithms, and visualizations focusing on relationships between cell clades. This includes new ways of clustering, plotting, choosing differential expression comparisons. Identifies and visualizes relationships of single-cell clades. Spectral clustering, radial tree, visualization, cell clades, is related to: too-many-cells-python
is related to: TooManyCellsInteractive
NCI T32 CA009140;
NCI R01 CA215518;
NHLBI R01 HL145754;
Sloan Foundation ;
NCI R01 CA230800
PMID:32123397 Free, Available for download, Freely available https://gregoryschwartz.github.io/too-many-cells/ SCR_025328 2026-02-12 09:48:25 4
Borzoi
 
Resource Report
Resource Website
1+ mentions
Borzoi (RRID:SCR_026619) software toolkit, software resource, source code Software package to access the Borzoi models, which are convolutional neural networks trained to predict RNA-seq coverage at 32bp resolution given 524kb input sequences. Borzoi models access, convolutional neural networks, predict RNA-seq coverage, Common Fund of the Office of the Director ;
NCI ;
NHGRI ;
NHLBI ;
NIDA ;
NIMH ;
NINDS
PMID:39779956 Free, Available for download, Freely available SCR_026619 2026-02-12 09:48:38 1
NetworkDataCompanion
 
Resource Report
Resource Website
1+ mentions
NetworkDataCompanion (RRID:SCR_026532) source code, software library, software resource, software toolkit Software R library of utilities for performing analyses on TCGA and GTEx data using the Network Zoo. Streamlines routine steps in TCGA data processing, including filtering and mapping gene and sample identifiers between modalities and allows modality-specific data transformation, such as normalization and cleaning. TCGA and GTEx data analysis, TCGA data processing, filtering and mapping gene, normalization and cleaning, NCI R35CA220523;
NCI U24CA231846;
NCI P50CA127003;
NHGRI R01HG011393;
NHGRI R01HG125975;
NHLBI P01HL114501;
NHLBI T32HL007427;
NHLBI K01HL166376;
American Lung Association
PMID:39574772 Free, Available for download, Freely available SCR_026532 2026-02-12 09:49:06 1
ped-sim
 
Resource Report
Resource Website
1+ mentions
ped-sim (RRID:SCR_026957) simulation software, source code, software application, software resource Software tool to simulate pedigree structures. Used for simulating relatives that can utilize either sex-specific or sex averaged genetic maps and also either model of crossover interference or traditional Poisson model for inter-crossover distances. Pedigree simulator, simulate pedigree structures, simulating relatives, sex-specific, sex averaged, genetic maps, NIGMS R35 GM133805;
Alfred P. Sloan Research Fellowship ;
United States-Israel Binational Science Foundation ;
NHLBI R01 HL0113323;
NHLBI P01 HL045222;
NIDDK R01 DK047482;
NIDDK R01 DK053889;
NIGMS T32 GM007617;
NIGMS T32 GM083937;
Wellcome Trust
PMID:31860654 Free, Available for download, Freely available SCR_026957 Ped-sim 2026-02-12 09:48:43 2
BEERS2
 
Resource Report
Resource Website
BEERS2 (RRID:SCR_027287) simulation software, source code, software application, software resource Software for simulation of RNA-seq reads. Combines flexible and highly configurable design with detailed simulation of entire library preparation and sequencing pipeline and is designed to include effects of polyA selection and RiboZero for ribosomal depletion, hexamer priming sequence biases, GC-content biases in polymerase chain reaction (PCR) amplification, barcode read errors and errors during PCR amplification. RNA-seq reads, simulation of RNA-seq reads, NCATS 5UL1TR000003;
NHLBI R01HL155934;
NHLBI R01HL147472;
NIGMS DP2GM146251
PMID:38605641 Free, Available for download, Freely available SCR_027287 2026-02-12 09:49:11 0

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