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SciCrunch Registry is a curated repository of scientific resources, with a focus on biomedical resources, including tools, databases, and core facilities - visit SciCrunch to register your resource.

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Resource Name Proper Citation Abbreviations Resource Type Description Keywords Resource Relationships Related Condition Funding Defining Citation Availability Website Status Alternate IDs Alternate URLs Old URLs Parent Organization Resource ID Synonyms Record Last Update Mentions Count
SCAN.UPC
 
Resource Report
Resource Website
10+ mentions
SCAN.UPC (RRID:SCR_001334) SCAN.UPC software resource A microarray normalization software (SCAN) to facilitate personalized-medicine workflows with an extension (UPC) that estimates whether a given gene/transcript is active above background levels in a given sample. Rather than processing microarray samples as groups, which can introduce biases and present logistical challenges, SCAN normalizes each sample individually by modeling and removing probe- and array-specific background noise using only data from within each array. SCAN can be applied to one-channel (e.g., Affymetrix) or two-channel (e.g., Agilent) microarrays. The UPC method can be applied to one-channel or two-channel microarrays as well as to RNA-Seq read counts. Because UPC values are represented on the same scale and have an identical interpretation for each platform, they can be used for cross-platform data integration. A microarray, one channel, preprocessing, rna-seq, two channel is listed by: OMICtools
has parent organization: Bioconductor
Free, Available for download, Freely available OMICS_02006 SCR_001334 Single-channel array normalization (SCAN) and Universal exPression Codes (UPC), Single-channel array normalization and Universal exPression Codes 2026-02-07 02:05:30 11
SNM
 
Resource Report
Resource Website
1+ mentions
SNM (RRID:SCR_001299) SNM software resource Software package that uses a modeling strategy especially designed for normalizing high-throughput genomic data. The premise is that your data is a function of study-specific variables which are either biological variables that represent the target of the statistical analysis, or adjustment variables that represent factors arising from the experimental or biological setting the data is drawn from. The SNM approach aims to simultaneously model all study-specific variables in order to more accurately characterize the biological or clinical variables of interest. differential expression, exon array, gene expression, microarray, multi channel, multiple comparison, one channel, preprocessing, quality control, transcription, two channel is listed by: OMICtools
has parent organization: Bioconductor
Free, Available for download, Freely available OMICS_02036 SCR_001299 Supervised Normalization of Microarrays 2026-02-07 02:05:30 1
betr
 
Resource Report
Resource Website
10+ mentions
betr (RRID:SCR_001332) betr software resource Software package that implements the Bayesian Estimation of Temporal Regulation algorithm to identify differentially expressed genes in microarray time-course data. differentially expression, gene, microarray, time-course is listed by: OMICtools
has parent organization: Bioconductor
PMID:20003283 Free, Available for download, Freely available OMICS_01997 http://www.bioconductor.org/packages/release/bioc/html/betr.html SCR_001332 Bayesian Estimation of Temporal Regulation 2026-02-07 02:05:31 17
gprege
 
Resource Report
Resource Website
1+ mentions
gprege (RRID:SCR_001324) gprege software resource Software R package for Gaussian Process Ranking and Estimation of Gene Expression time-series. The software fits two Gaussian processes (GPs) with an radial basis function (RBF) (+ noise diagonal) kernel on each profile. One GP kernel is initialized wih a short lengthscale hyperparameter, signal variance as the observed variance and a zero noise variance. It is optimized via scaled conjugate gradients (netlab). A second GP has fixed hyperparameters: zero inverse-width, zero signal variance and noise variance as the observed variance. The log-ratio of marginal likelihoods of the two hypotheses acts as a score of differential expression for the profile. Comparison via receiver operating characteristic curves (ROC curves) is performed against Bayesian hierarchical model for the analysis of time-series (BATS) (Angelini et.al, 2007). differential expression, microarray, preprocessing, time course, bio.tools is listed by: OMICtools
is listed by: Debian
is listed by: bio.tools
has parent organization: Bioconductor
PMID:21599902 Free, Available for download, Freely available OMICS_02011, biotools:gprege http://www.bioconductor.org/packages/release/bioc/html/gprege.html SCR_001324 Gaussian Process Ranking and Estimation of Gene Expression time-series 2026-02-07 02:05:35 1
waveTiling
 
Resource Report
Resource Website
waveTiling (RRID:SCR_001322) waveTiling software resource Software package to conduct transcriptome analysis for tiling arrays based on fast wavelet-based functional models. differential expression, microarray, gene expression, time course is listed by: OMICtools
has parent organization: Bioconductor
PMID:22974078 Free, Available for download, Freely available OMICS_02014 http://www.bioconductor.org/packages/release/bioc/html/waveTiling.html SCR_001322 waveTiling - Wavelet-Based Models for Tiling Array Transcriptome Analysis 2026-02-07 02:05:29 0
AffyExpress
 
Resource Report
Resource Website
1+ mentions
AffyExpress (RRID:SCR_001321) AffyExpress software resource THIS RESOURCE IS NO LONGER IN SERVICE. Documented on September 23,2022. Software package for quality assessment and to identify differentially expressed genes in the Affymetrix gene expression data. differential expression, microarray, annotation, one channel, preprocessing, quality control, report writing, visualization, gene expression is listed by: OMICtools
has parent organization: Bioconductor
THIS RESOURCE IS NO LONGER IN SERVICE OMICS_02015 SCR_001321 AffyExpress - Affymetrix Quality Assessment and Analysis Tool 2026-02-07 02:05:35 2
beadarray
 
Resource Report
Resource Website
100+ mentions
beadarray (RRID:SCR_001314) beadarray software resource Software package to read bead-level data (raw TIFFs and text files) output by BeadScan as well as bead-summary data from BeadStudio. Methods for quality assessment and low-level analysis are provided. microarray, quality control, one channel, preprocessing, bio.tools is listed by: OMICtools
is listed by: Debian
is listed by: bio.tools
is listed by: SoftCite
has parent organization: Bioconductor
PMID:17586828 GNU General Public License, v2 OMICS_02021, biotools:beadarray https://bio.tools/beadarray SCR_001314 beadarray - Quality assessment and low-level analysis for Illumina BeadArray data 2026-02-07 02:05:35 119
arrayMvout
 
Resource Report
Resource Website
1+ mentions
arrayMvout (RRID:SCR_001317) arrayMvout software resource Software package that supports the application of diverse quality metrics to AffyBatch instances, summarizing these metrics via PCA, and then performing parametric outlier detection on the PCs to identify aberrant arrays with a fixed Type I error rate. infrastructure, microarray, quality control is listed by: OMICtools
has parent organization: Bioconductor
Free, Available for download, Freely available OMICS_02019 SCR_001317 arrayMvout - Multivariate outlier detection for expression array QA 2026-02-07 02:05:30 1
affyQCReport
 
Resource Report
Resource Website
10+ mentions
affyQCReport (RRID:SCR_001318) affyQCReport software resource Software package to create a QC report for an AffyBatch object. The report is intended to allow the user to quickly assess the quality of a set of arrays in an AffyBatch object. microarray, one channel, quality control is listed by: OMICtools
has parent organization: Bioconductor
Free, Available for download, Freely available OMICS_02018 http://www.bioconductor.org/packages/release/bioc/html/affyQCReport.html SCR_001318 affyQCReport - QC Report Generation for affyBatch objects 2026-02-07 02:05:35 44
maigesPack
 
Resource Report
Resource Website
maigesPack (RRID:SCR_001351) maigesPack software resource Software package that uses functions to handle and analyze cDNA microarray data. classification, clustering, differential expression, graph, network, microarray, preprocessing is listed by: OMICtools
has parent organization: Bioconductor
Free, Available for download, Freely available OMICS_01988 http://www.bioconductor.org/packages/release/bioc/html/maigesPack.html SCR_001351 2026-02-07 02:05:30 0
MDQC
 
Resource Report
Resource Website
MDQC (RRID:SCR_001352) MDQC software resource A multivariate quality assessment software for microarrays based on quality control (QC) reports. The Mahalanobis distance of an array's quality attributes is used to measure the similarity of the quality of that array against the quality of the other arrays. Then, arrays with unusually high distances can be flagged as potentially low-quality. microarray, quality control is listed by: OMICtools
has parent organization: Bioconductor
PMID:17933854 Free, Available for download, Freely available OMICS_01987 SCR_001352 Mahalanobis Distance Quality Control for microarrays 2026-02-07 02:05:31 0
MACAT
 
Resource Report
Resource Website
MACAT (RRID:SCR_001350) MACAT software resource Software library that contains functions to investigate links between differential gene expression and the chromosomal localization of the genes. It is motivated by the common observation of phenomena involving large chromosomal regions in tumor cells. MACAT is the implementation of a statistical approach for identifying significantly differentially expressed chromosome regions. differential expression, microarray, visualization, bio.tools is listed by: OMICtools
is listed by: bio.tools
is listed by: Debian
has parent organization: Bioconductor
PMID:15572464 THIS RESOURCE IS NO LONGER IN SERVICE OMICS_01989, biotools:macat https://bio.tools/macat SCR_001350 MicroArray Chromosome Analysis Tool 2026-02-07 02:05:36 0
nnNorm
 
Resource Report
Resource Website
nnNorm (RRID:SCR_001354) nnNorm software resource Software package that allows to detect and correct for spatial and intensity biases with two-channel microarray data. The normalization method implemented in this package is based on robust neural networks fitting. microarray, preprocessing is listed by: OMICtools
has parent organization: Bioconductor
Free, Available for download, Freely available OMICS_01985 SCR_001354 nnNorm - Spatial and intensity based normalization of cDNA microarray data based on robust neural nets 2026-02-07 02:05:30 0
maCorrPlot
 
Resource Report
Resource Website
1+ mentions
maCorrPlot (RRID:SCR_001348) maCorrPlot software resource Software that graphically displays correlation in microarray data that is due to insufficient normalization. microarray, preprocessing, visualization is listed by: OMICtools
has parent organization: Bioconductor
PMID:15799785 Free, Available for download, Freely available OMICS_01991 SCR_001348 maCorrPlot - Visualize artificial correlation in microarray data 2026-02-07 02:05:30 2
lapmix
 
Resource Report
Resource Website
lapmix (RRID:SCR_001347) lapmix software resource Software to identify differentially expressed genes. A hierarchical Bayesian approach is used, and the hyperparameters are estimated using empirical Bayes. differential expression, microarray, bio.tools is listed by: OMICtools
is listed by: Debian
is listed by: bio.tools
has parent organization: Bioconductor
Free, Available for download, Freely available biotools:lapmix, OMICS_01992 https://bio.tools/lapmix SCR_001347 Laplace Mixture Model in Microarray Experiments 2026-02-07 02:05:36 0
OCplus
 
Resource Report
Resource Website
1+ mentions
OCplus (RRID:SCR_001342) OCplus software resource Software package that allows to characterize the operating characteristics of a microarray experiment, i.e. the trade-off between false discovery rate and the power to detect truly regulated genes. The package includes tools both for planned experiments (for sample size assessment) and for already collected data (identification of differentially expressed genes). differential expression, microarray, multiple comparison is listed by: OMICtools
has parent organization: Bioconductor
PMID:16368770 Free, Available for download, Freely available OMICS_01999 SCR_001342 Ocplus - Operating characteristics plus sample size and local fdr for microarray experiments 2026-02-07 02:05:30 1
bridge
 
Resource Report
Resource Website
100+ mentions
bridge (RRID:SCR_001343) bridge software resource Software package to test for differentially expressed genes with microarray data. It can be used with both cDNA microarrays or Affymetrix chip. The packge fits a robust Bayesian hierarchical model for testing for differential expression. Outliers are modeled explicitly using a $t$-distribution. The model includes an exchangeable prior for the variances which allow different variances for the genes but still shrink extreme empirical variances. The model can be used for testing for differentially expressed genes among multiple samples, and can distinguish between the different possible patterns of differential expression when there are three or more samples. Parameter estimation is carried out using a novel version of Markov Chain Monte Carlo that is appropriate when the model puts mass on subspaces of the full parameter space. cdna microarray, affymetrix chip, differential expression, microarray, bio.tools is listed by: OMICtools
is listed by: Debian
is listed by: bio.tools
has parent organization: Bioconductor
PMID:16542223 Free, Available for download, Freely available OMICS_01996, biotools:bridge http://www.bioconductor.org/packages/release/bioc/html/bridge.html SCR_001343 Bayesian Robust Inference for Differential Gene Expression 2026-02-07 02:05:31 154
CALIB
 
Resource Report
Resource Website
100+ mentions
CALIB (RRID:SCR_001338) CALIB software resource Software package that contains functions for normalizing spotted microarray data, based on a physically motivated calibration model. The model parameters and error distributions are estimated from external control spikes. microarray, preprocessing is listed by: OMICtools
has parent organization: Bioconductor
PMID:17485432 Free, Available for download, Freely available OMICS_02003 http://www.bioconductor.org/packages/release/bioc/html/CALIB.html SCR_001338 2026-02-07 02:05:36 131
LPE
 
Resource Report
Resource Website
LPE (RRID:SCR_001364) LPE software resource Software library used to do significance analysis of microarray data with small number of replicates. It uses resampling based FDR adjustment, and gives less conservative results than traditional "BH" or "BY" procedures. Data accepted is raw data in txt format from MAS4, MAS5 or dChip. Data can also be supplied after normalization. LPE library is primarily used for analyzing data between two conditions. differential expression, microarray is listed by: OMICtools
has parent organization: Bioconductor
PMID:18450812 Free, Available for download, Freely available OMICS_01978 SCR_001364 Local Pooled Error 2026-02-07 02:05:36 0
aroma.light
 
Resource Report
Resource Website
1+ mentions
aroma.light (RRID:SCR_001312) aroma.light software resource Light-weight software package for normalization and visualization of microarray data using only basic R data types. Software can be used standalone, be utilized in other packages, or be wrapped up in higher-level classes. infrastructure, microarray, preprocessing, visualization, bio.tools is listed by: OMICtools
is listed by: Debian
is listed by: bio.tools
has parent organization: Bioconductor
DOI:10.1186/1471-2105-11-245 Free, Available for download, Freely available OMICS_01998, biotools:aroma.light https://bio.tools/aroma.light
https://sources.debian.org/src/r-bioc-aroma.light/
SCR_001312 2026-02-07 02:05:29 1

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