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SciCrunch Registry is a curated repository of scientific resources, with a focus on biomedical resources, including tools, databases, and core facilities - visit SciCrunch to register your resource.

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Resource Name Proper Citation Abbreviations Resource Type Description Keywords Resource Relationships Related Condition Funding Defining Citation Availability Website Status Alternate IDs Alternate URLs Old URLs Parent Organization Resource ID Synonyms Record Last Update Mentions Count
Slingshot
 
Resource Report
Resource Website
50+ mentions
Slingshot (RRID:SCR_017012) software application, data processing software, software resource Software R package for identifying and characterizing continuous developmental trajectories in single cell data. Cell lineage and pseudotime inference for single-cell transcriptomics. identify, characterize, continuous, developmental, trajectory, single, cell, data, lineage, pseudotime, inference, transcriptomic is used by: Totem NIMH U01 MH105979;
NIDCD R01 DC007235;
NCRR S10 RR029668;
Siebel Foundation ;
NIA K01 AG045344;
NHGRI T32 HG000047;
California Institute of Regenerative Medicine
PMID:29914354 Free, Available for download, Freely available SCR_017012 2026-02-17 10:02:47 84
Human Reference Protein Interactome Project
 
Resource Report
Resource Website
10+ mentions
Human Reference Protein Interactome Project (RRID:SCR_015670) HuRI web application, data or information resource, project portal, database, software resource, portal Project portal for the Human Reference Protein Interactome Project, which aims generate a first reference map of the human protein-protein interactome network by identifying binary protein-protein interactions (PPIs). It achieves this by systematically interrogating all pairwise combinations of predicted human protein-coding genes using proteome-scale technologies. protein interactome, protein-protein interaction, ppi, pairwise combination, proteome, human reference NHGRI R01/U01HG001715;
NHGRI P50HG004233;
NHLBI U01HL098166;
NHLBI U01HL108630;
NCI U54CA112962;
NCI R33CA132073;
NIH RC4HG006066;
NICHD ARRA R01HD065288;
NICHD ARRA R21MH104766;
NICHD ARRA R01MH105524;
NIMH R01MH091350;
NSF CCF-1219007;
NSERC RGPIN-2014-03892
PMID:25416956 Freely Available, Free, Available for download SCR_015670 HuRI: The Human Reference Protein Interactome Mapping Project 2026-02-17 10:03:18 20
Computational Analysis of gene Family Evolution
 
Resource Report
Resource Website
10+ mentions
Computational Analysis of gene Family Evolution (RRID:SCR_018924) CAFE data analysis software, software application, data processing software, software resource Software tool for computational analysis of gene family evolution. Used for statistical analysis of evolution gene family sizes. Models evolution of gene family sizes over phylogeny. Computational analysis, gene family evolution, evolution statistical analysis, gene family size, gene evolution, phylogeny has parent organization: Indiana University; Indiana; USA NHGRI R33 HG003070;
NSF MCB 0528465;
METACyt Initiative of Indiana University ;
Lilly Endowment ;
Inc
PMID:16543274 SCR_018924 CAFE v2.0, CAFE v4.0, CAFE v3.0, CAFE v5.0, Computational Analysis of gene Family Evolution 2026-02-17 10:03:10 16
Drop-seq tools
 
Resource Report
Resource Website
50+ mentions
Drop-seq tools (RRID:SCR_018142) data analysis software, software application, data processing software, software resource Software Java tools for analyzing Drop-seq data. Used to analyze gene expression from thousands of individual cells simultaneously. Analyzes mRNA transcripts while remembering origin cell transcript. Simultaneous analysis, Drop-seq data, gene expression, thousands individual cells is listed by: Debian
has parent organization: Broad Institute
Stanley Center for Psychiatric Research ;
MGH Psychiatry Residency Research Program ;
Stanley-MGH Fellowship in Psychiatric Neuroscience ;
Stewart Trust Fellows Award ;
Simons Foundation ;
NHGRI P50 HG006193;
Klarman Cell Observatory ;
NIMH U01 MH105960;
NIMH R25 MH094612;
NICHD F32 HD075541;
NSF ECS 0335765;
NSF DMR 1310266;
NSF DMR 1420570
PMID:26000488 https://sources.debian.org/src/drop-seq-tools/ SCR_018142 Droplet sequencing tools, Droplet sequencing data analysis software tools 2026-02-17 10:03:42 94
Shannon
 
Resource Report
Resource Website
1+ mentions
Shannon (RRID:SCR_017037) data analysis software, software application, data processing software, software resource Software tool for de novo transcriptome assembly from RNA-Seq data. de novo, transcriptome, assembly, RNAseq, data has parent organization: University of Washington; Seattle; USA
has parent organization: University of California at Berkeley; Berkeley; USA
has parent organization: Stanford University; Stanford; California
NSF Center for Science of Information ;
NHGRI ;
University of Washington
Free, Available for download, Freely available http://sreeramkannan.github.io/Shannon/ SCR_017037 2026-02-17 10:03:08 1
SNPRelate
 
Resource Report
Resource Website
10+ mentions
SNPRelate (RRID:SCR_022719) data analysis software, software application, data processing software, software resource Software R package as parallel computing toolset for relatedness and principal component analysis of SNP data. parallel computing, relatedness and principal component analysis, SNP data analysis NHGRI U01 HG 004446 PMID:23060615 Free, Available for download, Freely available https://github.com/zhengxwen/SNPRelate SCR_022719 2026-02-17 10:03:43 12
hifiasm-meta
 
Resource Report
Resource Website
1+ mentions
hifiasm-meta (RRID:SCR_022771) data analysis software, software application, data processing software, software resource Software tool as metagenome assembler that exploits high accuracy of recent data. De novo metagenome assembler, based on haplotype resolved de novo assembler for PacBio Hifi reads. Workflow consists of optional read selection, sequencing error correction, read overlapping, string graph construction and graph cleaning. Error correction, read overlapping, hifiasm, haplotype resolved de novo assembler, PacBio Hifi reads NHGRI R01HG010040;
NHGRI U01HG010971
PMID:35534630 Free, Available for download, Freely available SCR_022771 hifiasm_meta 2026-02-17 10:04:25 2
ComplexUpset
 
Resource Report
Resource Website
10+ mentions
ComplexUpset (RRID:SCR_022752) data analysis software, software application, data processing software, software resource Software R package for visualization of intersecting sets. Used for quantitative analysis of sets, their intersections, and aggregates of intersections. Visualizes set intersections in matrix layout and introduces aggregates based on groupings and queries. visualization of intersecting sets, set intSections in matrix layout, aggregates based on groupings and queries, quantitative analysis of sets uses: ggplot2
is listed by: CRAN
Austrian Science Fund ;
Air Force Research Laboratory and DARPA ;
NHGRI K99 HG007583
PMID:26356912 Free, Available for download, Freely available SCR_022752 2026-02-17 10:04:17 18
sei
 
Resource Report
Resource Website
1+ mentions
sei (RRID:SCR_022571) data access protocol, web service, software resource Web server for systematically predicting sequence regulatory activities and applying sequence information to human genetics data. Provides global map from any sequence to regulatory activities, as represented by sequence classes, and each sequence class integrates predictions for chromatin profiles like transcription factor, histone marks, and chromatin accessibility profiles across wide range of cell types. systematically predicting sequence regulatory activities, applying sequence information, human genetics data, sequence class predictions National Science Foundation Graduate Research Fellowship Program ;
NHGRI R01HG005998;
NHLBI U54HL117798;
NIGMS R01GM071966
PMID:35817977 Free, Available for download, Freely available https://hb.flatironinstitute.org/sei SCR_022571 2026-02-17 10:04:22 6
UpSet
 
Resource Report
Resource Website
10+ mentions
UpSet (RRID:SCR_022731) software application, data processing software, data analysis software, software resource, data visualization software Software tool to visualize set intersections in matrix layout. Interactive, web based visualization technique designed to analyze set based data. Visualizes both, set intersections and their properties, and elements in dataset. Used for quantitative analysis of data with more than three sets. visualize set intersections, matrix layout, intersecting sets, more than three sets quantitative data analysis Austrian Science Fund ;
Air Force Research Laboratory ;
DARPA ;
NHGRI K99 HG007583
PMID:26356912 Free, Available for download, Freely available https://github.com/VCG/upset SCR_022731 UpSet Plot 2026-02-17 10:04:17 16
SvABA
 
Resource Report
Resource Website
10+ mentions
SvABA (RRID:SCR_022998) software application, data processing software, data analysis software, software resource, sequence analysis software Software tool for detecting structural variants in sequencing data using genome wide local assembly. Genome wide detection of structural variants and indels by local assembly. Used for detecting SVs from short read sequencing data using genome wide local assembly with low memory and computing requirements. genome wide detection, structural variants, indels, local assembly NHGRI T32 HG002295;
NCI U54CA143798;
NCI R01CA188228;
DFCI-Novartis Drug Discovery Program ;
Voices Against Brain Cancer ;
Pediatric Low-Grade Astrocytoma Foundation ;
Broad Institute ;
Wellcome Fund Career Award for Medical Scientists
PMID:29535149 Free, Available for download, Freely available SCR_022998 2026-02-17 10:04:15 14
HetMatPy
 
Resource Report
Resource Website
1+ mentions
HetMatPy (RRID:SCR_023409) software application, data processing software, data analysis software, software resource, network analysis software Software Python package for matrix storage and operations on hetnets. Enables identifying relevant network connections between set of query nodes. Hetionet, matrix storage, operations on hetnets, hetnets, heterogeneous networks, Gordon and Betty Moore Foundation ;
NHGRI R01 HG010067;
NCI R01 CA237170
PMID:36711546 Free, Available for download, Freely available SCR_023409 hetmatpy 2026-02-17 10:04:22 1
Alfred
 
Resource Report
Resource Website
10+ mentions
Alfred (RRID:SCR_023354) algorithm resource, web application, software resource Web application as interactive multi-sample BAM alignment statistics, feature counting and feature annotation for long- and short-read sequencingas. alignment, BAM, quality control, cell barcode splitting, annotation directed improvement, BAM alignment statistics, feature counting, feature annotation. NHGRI U41HG007497 PMID:30520945 Free, Available for download, Freely available https://bio.tools/alfred SCR_023354 2026-02-17 10:04:20 15
UpSetPlot
 
Resource Report
Resource Website
1+ mentions
UpSetPlot (RRID:SCR_023225) data visualization software, data processing software, software application, software resource Software Python implementation of UpSet plots to visualize set overlaps. UpSet plots, Python, visualize set overlaps, Austrian Science Fund ;
Air Force Research Laboratory ;
DARPA ;
NHGRI K99 HG007583
PMID:26356912 Free, Available for download, Freely available SCR_023225 2026-02-17 10:03:50 6
UCSC Cell Browser
 
Resource Report
Resource Website
100+ mentions
UCSC Cell Browser (RRID:SCR_023293) data access protocol, web service, software resource Web based tool to visualize gene expression and metadata annotation distribution throughout single cell dataset or multiple datasets. Interactive viewer for single cell expression. You can click on and hover over cells to get meta information, search for genes to color on and click clusters to show cluster specific marker genes. visualize gene expression, metadata annotation distribution, single cell data viewer, cluster specific marker genes, single cell expression, is related to: Allen Institute for Brain Science
is related to: BRAIN Initiative Cell Atlas Network
has parent organization: University of California at Santa Cruz; California; USA
NHGRI 5U41HG002371;
NHGRI 1U41HG010972;
NHGRI 5R01HG010329;
NIMH U01MH114825;
NINDS K99 NS111731;
NIMH RF1MH121268;
NIMH DP2MH122400;
Silicon Valley Community Foundation ;
California Institute for Regenerative Medicine ;
University of California Office of the President Emergency COVID-19 Research Seed Funding ;
Chan Zuckerberg Initiative Foundation ;
Simons Foundation ;
Brain and Behavior Research Foundation
PMID:34244710 Free, Freely available https://cellbrowser.readthedocs.io/en/master/
https://github.com/maximilianh/cellBrowser
SCR_023293 2026-02-17 10:04:24 123
Kourami
 
Resource Report
Resource Website
1+ mentions
Kourami (RRID:SCR_022280) software application, data processing software, software resource Software graph guided assembly for novel human leukocyte antigen allele discovery. Graph guided assembly for HLA haplotypes covering typing exons using high coverage whole genome sequencing data.Implemented in Java and supported on Linux and Mac OS X. graph guided assembly, novel human leukocyte antigen allele discovery, HLA alleles, HLA alleles assembly Gordon and Betty Moore Foundation ;
NSF CCF1256087;
NSF CCF1319998;
NHGRI R01HG007104
PMID:29415772 Free, Available for download, Freely available SCR_022280 2026-02-17 10:04:01 4
bioPIXIE
 
Resource Report
Resource Website
1+ mentions
bioPIXIE (RRID:SCR_004182) bioPIXIE data analysis service, production service resource, analysis service resource, service resource bioPIXIE is a general system for discovery of biological networks through integration of diverse genome-wide functional data. This novel system for biological data integration and visualization, allows you to discover interaction networks and pathways in which your gene(s) (e.g. BNI1, YFL039C) of interest participate. The system is based on a Bayesian algorithm for identification of biological networks based on integrated diverse genomic data. To start using bioPIXIE, enter your genes of interest into the search box. You can use ORF names or aliases. If you enter multiple genes, they can be separated by commas or returns. Press ''submit''. bioPIXIE uses a probabilistic Bayesian algorithm to identify genes that are most likely to be in the same pathway/functional neighborhood as your genes of interest. It then displays biological network for the resulting genes as a graph. The nodes in the graph are genes (clicking on each node will bring up SGD page for that gene) and edges are interactions (clicking on each edge will show evidence used to predict this interaction). Most likely, the first results to load on the results page will be a list of significant Gene Ontology terms. This list is calculated for the genes in the biological network created by the bioPIXIE algorithm. If a gene ontology term appears on this list with a low p-value, it is statistically significantly overrepresented in this biological network. As you move the mouse over genes in the network, interactions involving these genes are highlighted. If you click on any of the highlighted interactions graph, evidence pop-up window will appear. The Evidence pop-up lists all evidence for this interaction, with links to the papers that produced this evidence - clicking these links will bring up the relevant source citation(s) in PubMed. You may need to download the Adobe Scalable Vector Graphic (SVG) plugin to utilize the visualization tool (you will be prompted if you need it). prediction, bayesian network, probabilistic, interaction, network has parent organization: Princeton University; New Jersey; USA NHGRI T32 HG003284;
NIGMS R01 GM071966;
NHGRI R01 HG003471;
NIGMS P50 GM071508;
NSF DGE-9972930;
NSF IIS-0513552
PMID:16420673 nlx_20893 SCR_004182 biological Process Inference from eXperimental Interaction Evidence 2026-02-17 10:00:33 1
T-profiler
 
Resource Report
Resource Website
10+ mentions
T-profiler (RRID:SCR_003452) T-profiler data analysis service, production service resource, analysis service resource, service resource One of the key challenges in the analysis of gene expression data is how to relate the expression level of individual genes to the underlying transcriptional programs and cellular state. The T-profiler tool hosted on this website uses the t-test to score changes in the average activity of pre-defined groups of genes. The gene groups are defined based on Gene Ontology categorization, ChIP-chip experiments, upstream matches to a consensus transcription factor binding motif, and location on the same chromosome, respectively. If desired, an iterative procedure can be used to select a single, optimal representative from sets of overlapping gene groups. A jack-knife procedure is used to make calculations more robust against outliers. T-profiler makes it possible to interpret microarray data in a way that is both intuitive and statistically rigorous, without the need to combine experiments or choose parameters. Currently, gene expression data from Saccharomyces cerevisiae and Candida albicans are supported. Users can submit their microarray data for analysis by clicking on one of the two organism-specific tabs above. Platform: Online tool expression, gene, binding, cellular, transcriptional, gene expression, microarray, gene ontology, transcription factor, binding motif, chip-chip, chip, motif, t-test, statistical analysis, transcriptome, bio.tools is listed by: Biositemaps
is listed by: Gene Ontology Tools
is listed by: Debian
is listed by: bio.tools
is related to: Gene Ontology
has parent organization: Columbia University; New York; USA
has parent organization: University of Amsterdam; Amsterdam; Netherlands
Netherlands Foundation for Technical Research APB.5504;
NHGRI R01HG003008
PMID:15980543 Free for academic use nif-0000-33354, biotools:t-profiler https://bio.tools/t-profiler SCR_003452 T-profiler: Scoring the Activity of Pre-defined Groups of Genes Using Gene Expression Data 2026-02-17 10:00:11 11
Belvu
 
Resource Report
Resource Website
10+ mentions
Belvu (RRID:SCR_015989) software application, data processing software, software resource, image analysis software, alignment software Software for multiple sequence alignment viewing, editing and phylogeny. It includes a set of user-configurable modes to color residues used to create high-quality reference alignments. editing, phylogeny, sequence, alignment, phylogenetic, viewer, multiple, editor, color, residue, reference is related to: SEQtools
has parent organization: Wellcome Trust Sanger Institute; Hinxton; United Kingdom
Wellcome Trust Grant 098051;
NHGRI U54 HG00455
PMID:26801397 Free, Available for download SCR_015989 2026-02-17 10:02:56 18
Dotter
 
Resource Report
Resource Website
50+ mentions
Dotter (RRID:SCR_016080) alignment software, data visualization software, software application, data processing software, data analysis software, software resource, sequence analysis software, image analysis software Software for sequence alignment that is a graphical dot-matrix program for detailed comparison of two sequences. sequence, alignment, graphical, dot-matrix, program, comparison, two, detail is related to: SEQtools
has parent organization: Wellcome Trust Sanger Institute; Hinxton; United Kingdom
Wellcome Trust Grant 098051;
NHGRI U54 HG00455
PMID:26801397 Free, Available for download SCR_016080 Seqtools Dotter 2026-02-17 10:03:17 84

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