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Resource Name Proper Citation Abbreviations Resource Type Description Keywords Resource Relationships Related Condition Funding Defining Citation Availability Website Status Alternate IDs Alternate URLs Old URLs Parent Organization Resource ID Synonyms Record Last Update Mentions Count
Pathbase
 
Resource Report
Resource Website
10+ mentions
Pathbase (RRID:SCR_006141) Pathbase ontology, database, software resource, data access protocol, web service, service resource, storage service resource, data repository, data or information resource, image collection, controlled vocabulary, image repository Database of histopathology photomicrographs and macroscopic images derived from mutant or genetically manipulated mice. The database currently holds more than 1000 images of lesions from mutant mice and their inbred backgrounds and further images are being added continuously. Images can be retrieved by searching for specific lesions or class of lesion, by genetic locus, or by a wide set of parameters shown on the Advanced Search Interface. Its two key aims are: * To provide a searchable database of histopathology images derived from experimental manipulation of the mouse genome or experiments conducted on genetically manipulated mice. * A reference / didactic resource covering all aspects of mouse pathology Lesions are described according to the Pathbase pathology ontology developed by the Pathbase European Consortium, and are available at the site or on the Gene Ontology Consortium site - OBO. As this is a community resource, they encourage everyone to upload their own images, contribute comments to images and send them their feedback. Please feel free to use any of the SOAP/WSDL web services. (under development) histopathology, photomicrograph, macroscopic, mutant, genetically manipulated, pathology, transgenic, rodent, mpath ontology, mouse pathology ontology, skinbase, genotype, skin, gene, tissue, hair, mutant mouse strain, bio.tools is listed by: bio.tools
is listed by: Debian
is related to: Gene Ontology
has parent organization: University of Cambridge; Cambridge; United Kingdom
is parent organization of: Mouse Pathology Ontology
Lesion, Mutant mouse strain, Inbred mouse strain North American Hair Research Society ;
Ellison Medical Foundation ;
European Union QLRI-1999-00320;
European Union LSHG-CT-2006-037188;
NCI CA089713;
NCRR RR17436;
NIH AR49288
PMID:20587689
PMID:15623888
PMID:14681470
Except where otherwise noted, Creative Commons Attribution-NonCommercial-ShareAlike License, v3 Unported, Images on the database remain the property of the persons generously allowing their images to be used and are acknowledged within each record. Images should not be modified, Reproduced or disseminated without the express permission of the submitter. biotools:pathbase, nlx_151637 https://bio.tools/pathbase SCR_006141 Pathbase - European mutant mouse pathology database 2026-02-15 09:19:09 11
MRB - Mouse Resource Browser
 
Resource Report
Resource Website
1+ mentions
MRB - Mouse Resource Browser (RRID:SCR_005961) MRB source code, database, software resource, data access protocol, web service, registry, data or information resource Dynamic and interactive view of 222 world wide available mouse resources, classified in 22 categories. The massive generation of data has led to the propagation of mouse resources and databases and the concomitant need for formalized experimental descriptions, data standardization and database interoperability and integration. In this context and with these goals, information is collected through an online questionnaire and/or manual curation. All mouse resource data in MRB are broken up in four sections and presented in four tabs: * The General section/tab contains information such as URL(s), contact information, database description and categorization and related links. * The Ontologies & Standards tab indicates controlled vocabularies and data representation standards adopted by each resource, such as ontologies and minimum information standards. A hyperlink to an index of OBO and non-OBO ontologies can be found here; an index of minimum information standards can be found here. * The Technical tab holds technical information for each resource such as the server technology used, relational database management system(s) utilized, programming language(s) of implementation, schema descriptive documents or actual database dumps and most importantly information on each resource''s programmatic access, the integration and interoperability services. Additionally and through the integration with Molgenis, MRB is capable of generating a SOAP API for hosted resources. * The final section on Database Description Framework (DDF) Criteria, describes the compliance of each resource to the CASIMIR database criteria, which aim to capture key technical data about a database in a formal framework. All data in MRB are freely available to interested users through downloadable weekly database dumps. Programmatic access to some of MRB''s data is feasible via MRB''s SOAP web service. MRB is the front end of a relational, fully normalized PostgreSQL database. The source code is available under the GNU general public license (GPL) as a binary download and via cvs. registry, experimental description, data standardization, database interoperability, integration, minimum information standard, ontology, standard has parent organization: BSRC Al. Fleming; East Attica; Greece European Union LSHG-CT-2006-037811 Free, Source code is available under the GNU general public license., The community can contribute to this resource nlx_151623 SCR_005961 Mouse Resource Browser (MRB), Mouse Resource Browser 2026-02-15 09:19:06 2
Biobanking and Biomolecular Resources Research Infrastructure (BBMRI)
 
Resource Report
Resource Website
10+ mentions
Biobanking and Biomolecular Resources Research Infrastructure (BBMRI) (RRID:SCR_004226) BBMRI material resource, biomaterial supply resource BBMRI is a pan-European and internationally broadly accessible research infrastructure and a network of existing and de novo biobanks and biomolecular resources. The infrastructure will include samples from patients and healthy persons, representing different European populations (with links to epidemiological and health care information), molecular genomic resources and biocomputational tools to optimally exploit this resource for global biomedical research. During the past 3 years BBMRI has grown into a 53-member consortium with over 280 associated organizations (largely biobanks) from over 30 countries, making it the largest research infrastructure project in Europe. During the preparatory phase the concept of a functional pan-European biobank was formulated and has now been presented to Member States of the European Union and for associated states for approval and funding. BBMRI will form an interface between specimens and data (from patients and European populations) and top-level biological and medical research. This can only be achieved through a distributed research infrastructure with operational units in all participating Member States. BBMRI will be implemented under the ERIC (European Research Infrastructure Consortium) legal entity. BBMRI-ERIC foresees headquarters (central coordination) in Graz, Austria, responsible for coordination of the activities of National Nodes established in participating countries. BBMRI is in the process of submitting its application to the European Commission for a legal status under the ERIC regulation, with an expected start date at the end of 2011. Major synergism, gain of statistical power and economy of scale will be achieved by interlinking, standardizing and harmonizing - sometimes even just cross-referencing - a large variety of well-qualified, up-to date, existing and de novo national resources. The network should cover (1) major European biobanks with blood, serum, tissue or other biological samples, (2) molecular methods resource centers for human and model organisms of biomedical relevance, (3) and biocomputing centers to ensure that databases of samples in the repositories are dynamically linked to existing databases and to scientific literature as well as to statistical expertise. Catalog of European Biobanks www.bbmriportal.eu Username: guest / Password: catalogue The catalogue is intended to be used as a reference for scientists seeking information about biological samples and data suitable for their research. The BBMRI catalogue of European Biobanks provides a high-level description of Europe''s biobanks characteristics using a portal solution managing metadata and aggregate data of biobanks. The catalogue can be queried by country, by biobank, by ICD-groups, by specimen types, by specific strengths, by funding and more. A search function is available for all data. blood, serum, tissue, dna, cdna, rna, plasma, cell line, bodily fluid, urine, blood cell isolate, buffy coat, patient, healthy, normal, cryopreserved, paraffin embedded, clinical data is listed by: One Mind Biospecimen Bank Listing
is related to: BioResource Impact Factor
is related to: German Biobank Registry
is related to: BioMedBridges
is related to: Biological Resource Centre - National Institute for Cancer Research
has parent organization: Medical University of Graz; Graz; Austria
is parent organization of: BBMRI Wiki
All, Patient, Healthy, Normal European Union Public: The catalogue is intended to be used as a reference for scientists seeking information about biological samples and data suitable for their research. nlx_24389 http://www.bbmri.eu/index.php SCR_004226 Biobanking and Biomolecular Resources Research Infrastructure, BBMRI: Biobanking Biomolecular Resources Research Infrastructure, Biobanking Biomolecular Resources Research Infrastructure, BBMRI: Biobanking and Biomolecular Resources Research Infrastructure, Biobanking Biomolecular Resources Research Infrastructure (BBMRI) 2026-02-15 09:18:39 29
GenomEUtwin
 
Resource Report
Resource Website
1+ mentions
GenomEUtwin (RRID:SCR_002843) GenomEUtwin material resource, biomaterial supply resource THIS RESOURCE IS NO LONGER IN SERVICE, documented August 29, 2016. Study of genetic and life-style risk factors associated with common diseases based on analysis of European twins. The population cohorts used in the Genomeutwin study consist of Danish, Finnish, Italian, Dutch, English, Australian and Swedish twins and the MORGAM population cohort. This project will apply and develop new molecular and statistical strategies to analyze unique European twin and other population cohorts to define and characterize the genetic, environmental and life-style components in the background of health problems like obesity, migraine, coronary heart disease and stroke, representing major health care problems worldwide. The participating 8 twin cohorts form a collection of over 0.6 million pairs of twins. Tens of thousands of DNA samples with informed consents for genetic studies of common diseases have already been stored from these population-based twin cohorts. Studies targeted to cardiovascular traits are now being undertaken in MORGAM, a prospective case-cohort study. MORGAM cohorts include approximately 6000 individuals, drawn from population-based cohorts consisting of more than 80 000 participants who have donated DNA samples. genetic, environment, lifestyle, gene, disease is listed by: One Mind Biospecimen Bank Listing
is related to: KI Biobank - TwinGene
has parent organization: University of Helsinki; Helsinki; Finland
Twin European Union PMID:14624719 THIS RESOURCE IS NO LONGER IN SERVICE nif-0000-25218 SCR_002843 Studies of European Volunteer Twins to Identify Genes Underlying Common Diseases, GenomEUtwin Project, GenomeEUtwin 2026-02-15 09:18:25 1
Sanger Mouse Resources Portal
 
Resource Report
Resource Website
50+ mentions
Sanger Mouse Resources Portal (RRID:SCR_006239) Sanger Mouse Portal, WTSI Mouse Resources Portal, WTSI Mouse Resource Portal material resource, biomaterial supply resource Database of mouse research resources at Sanger: BACs, targeting vectors, targeted ES cells, mutant mouse lines, and phenotypic data generated from the Institute''''s primary screen. The Wellcome Trust Sanger Institute generates, characterizes, and uses a variety of reagents for mouse genetics research. It also aims to facilitate the distribution of these resources to the external scientific community. Here, you will find unified access to the different resources available from the Institute or its collaborators. The resources include: 129S7 and C57BL6/J bacterial artificial chromosomes (BACs), MICER gene targeting vectors, knock-out first conditional-ready gene targeting vectors, embryonic stem (ES) cells with gene targeted mutations or with retroviral gene trap insertions, mutant mouse lines, and phenotypic data generated from the Institute''''s primary screen. bacterial artificial chromosome, vector, embryonic stem cell, mutant mouse line, phenotype, gene, knockout, gene expression, genetics, chromosome, mutant, mouse line, mammal, marker symbol is listed by: One Mind Biospecimen Bank Listing
is related to: Ensembl
has parent organization: Wellcome Trust Sanger Institute; Hinxton; United Kingdom
Wellcome Trust 079643;
Wellcome Trust 098051;
NHGRI UO1-HG004080;
NCRR 1-U42RR033192;
European Union LSHG-CT-2006-037188;
European Union 227490;
European Union 312325;
European Union 261492
For the scientific community nlx_151819 SCR_006239 Mouse Resources Portal, Wellcome Trust Sanger Institute Mouse Resources Portal 2026-02-15 09:19:22 51
PRED-TMR2
 
Resource Report
Resource Website
1+ mentions
PRED-TMR2 (RRID:SCR_006205) PRED-TMR2 service resource, analysis service resource, data analysis service, production service resource A web server that classifies proteins into two classes from their sequences alone: the membrane protein class and the non-membrane protein class. This may be important in the functional assignment and analysis of open reading frames (ORF''s) identified in complete genomes and, especially, those ORF''s that correspond to proteins with unknown function. The network has a simple hierarchical feed-forward topology and a limited number of neurons which makes it very fast. By using only information contained in 11 protein sequences, the method was able to identify, with 100% accuracy, all membrane proteins with reliable topologies collected from several papers in the literature. Applied to a test set of 995 globular, water-soluble proteins, the neural network classified falsely 23 of them in the membrane protein class (97.7% of correct assignment). The method was also applied to the complete SWISS-PROT database with considerable success and on ORF''s of several complete genomes. The neural network developed was associated with the PRED-TMR algorithm (Pasquier,C., Promponas,V.J., Palaios,G.A., Hamodrakas,J.S. and Hamodrakas,S.J., 1999) in a new application package called PRED-TMR2. prediction, transmembrane, protein, algorithm, neural network, classification, transmembrane protein, protein classification, membrane protein, protein structure is related to: DAM-Bio
has parent organization: PRED-TMR
European Union ERBFMRXCT960019 PMID:10469822 nlx_151766 SCR_006205 PRED-TMR2: Prediction of Transmembrane regions in proteins 2026-02-15 09:19:11 1
PRED-TMR
 
Resource Report
Resource Website
1+ mentions
PRED-TMR (RRID:SCR_006203) PRED-TMR service resource, analysis service resource, data analysis service, production service resource A web server that predicts transmembrane domains in proteins using solely information contained in the sequence itself. The algorithm refines a standard hydrophobicity analysis with a detection of potential termini (edges, starts and ends) of transmembrane regions. This allows both to discard highly hydrophobic regions not delimited by clear start and end configurations and to confirm putative transmembrane segments not distinguishable by their hydrophobic composition. The accuracy obtained on a test set of 101 non homologous transmembranes proteins with reliable topologies compares well with that of other popular existing methods. Only a slight decrease in prediction accuracy was observed when the algorithm was applied to all transmembrane proteins of the SwissProt database (release 35). predict, transmembrane segment, protein, algorithm, sequence, membrane protein, protein structure, transmembrane region, hydrophobicity analysis is related to: waveTM
is related to: DAM-Bio
has parent organization: University of Athens Biophysics and Bioinformatics Laboratory
is parent organization of: PRED-TMR2
European Union ERBFMRXCT960019 PMID:10360978 nlx_151765 SCR_006203 PRED-TMR: A novel method for predicting transmembrane segment in proteins based on a statistical analysis of the SwissProt database 2026-02-15 09:19:11 7
FIVA - Functional Information Viewer and Analyzer
 
Resource Report
Resource Website
1+ mentions
FIVA - Functional Information Viewer and Analyzer (RRID:SCR_005776) FIVA software application, data processing software, software resource Functional Information Viewer and Analyzer (FIVA) aids researchers in the prokaryotic community to quickly identify relevant biological processes following transcriptome analysis. Our software is able to assist in functional profiling of large sets of genes and generates a comprehensive overview of affected biological processes. Currently, seven different modules containing functional information have been implemented: (i) gene regulatory interactions, (ii) cluster of orthologous groups (COG) of proteins, (iii) gene ontologies (GO), (iv) metabolic pathways (v) Swiss Prot keywords, (vi) InterPro domains - and (vii) generic functional categories. Platform: Windows compatible, Mac OS X compatible, Linux compatible, Unix compatible gene, gene expression, gene expression pattern, functional profile, statistical analysis, metabolic pathway, gene ontology, function, ortholog, gene regulatory interaction, biological process, transcriptome, visualization, analysis is listed by: Gene Ontology Tools
is related to: Gene Ontology
has parent organization: MolGen
Netherlands Organization for Scientific Research ;
industrial partners in the NWO-BMI project number 050.50.206 on Computational Genomics of Prokaryotes ;
Center IOP Genomics ;
European Union QLK3-CT-2001-01473
PMID:17237043 Free for academic use nlx_149245 SCR_005776 FIVA - Functional Information Viewer Analyzer, Functional Information Viewer and Analyzer (FIVA), Functional Information Viewer and Analyzer 2026-02-15 09:19:03 1
OpenAIRE
 
Resource Report
Resource Website
10+ mentions
OpenAIRE (RRID:SCR_013740) project portal, data or information resource, portal A research portal to share and obtain research data and journal articles openly accessible to all disciplines. Established to support the Open Access Policy, as set out by the ERC Scientific Council Guidelines for Open Access and the Open Access pilot launched by the European Commission. open access, Europe, repository networks, project portal, research data, journal articles is related to: ZENODO
is related to: Digital Repository Infrastructure Vision for European Research
European Union Free, Public SCR_013740 Open Access Infrastructure for Research in Europe 2026-02-15 09:20:33 34
Julearn
 
Resource Report
Resource Website
1+ mentions
Julearn (RRID:SCR_024881) software library, software toolkit, software resource Software library of easy testing ML models directly from pandas DataFrames, while keeping the flexibility of using scikit-learn’s models. machine learning open source, leakage free evaluation, inspection of ML models, testing ML models, Helmholtz-AI ZT-I-PF-5-078;
Helmholtz Supercomputing and Modeling for the Human Brain;
Deutsche Forschungsgemeinschaft PA 3634/1-1;
Deutsche Forschungsgemeinschaft 431549029–SFB 1451 project B05;
Helmoltz Imaging Platform NimRLS;
European Union HORIZON-INFRA-2021-TECH-01
DOI:10.48550/arXiv.2310.12568. Free, Available for download, Freely available https://github.com/juaml/julearn SCR_024881 2026-02-15 09:23:52 5
STARNET
 
Resource Report
Resource Website
1+ mentions
STARNET (RRID:SCR_025238) STARNET web service, data access protocol, source code, software resource Web interactive browser to visualize data and perform gene set enrichment analysis along with gene and SNP lookup. Web interface used to query STARNET datasets and downstream analysis which includes RNAseq from 7 tissues: blood, free internal mammary artery (MAM), atherosclerotic aortic root (AOR), subcutaneous fat (SF), visceral abdominal fat (VAF), skeletal muscle (SKLM), and liver (LIV). Paired SNP genotyping data is included and utilized for tissue expression quantitative trait loci (eQTL), CAD heritability (H2), co-expression networks and gene regulatory networks. cross-tissue co-expression analysis, STARNET multitissue gene expression data, cardiovascular disease patients, NHLBI R01HL125863;
American Heart Association ;
Swedish Research Council ;
Heart Lung Foundation ;
AstraZeneca ;
European Union ;
Federal German Ministries ;
ModulMax ;
NHLBI R01HL130423;
NHLBI R01HL135093;
NHLBI R01HL148167;
New South Wales health ;
NHLBI R01 HL144651;
NHLBI R01 HL147883;
NHLBI PO1 HL28481;
NIDDK R01 DK117850;
NHLBI HL138193
PMID:36276926 Free, Freely available https://github.com/skoplev/starnet SCR_025238 Stockholm-Tartu Atherosclerosis Reverse Networks Engineering Task 2026-02-15 09:23:48 5
Pathogens Portal Norway
 
Resource Report
Resource Website
Pathogens Portal Norway (RRID:SCR_025641) data or information resource, topical portal, disease-related portal, portal Portal provides information about available datasets, resources, tools, and services related to pandemic preparedness in Norway. Portal gives researchers, clinicians and policymakers access to collection of biomolecular data about pathogens. Norway, pandemic preparedness in Norway, pandemic data, pandemic, datasets, resources, tools, services, is related to: Pathogens Portal Netherlands European Union ;
ELIXIR Norway
Free, Freely available SCR_025641 2026-02-15 09:23:57 0
BRENDA
 
Resource Report
Resource Website
100+ mentions
BRENDA (RRID:SCR_002997) BRENDA data or information resource, database Database for functional enzyme and ligand-related information maintained as part of the German ELIXIR Node. Provides advanced query systems, evaluation tools, and various visualization options for the detailed assessment of enzyme properties. Enzyme data in BRENDA are classified according to the Enzyme Commission (EC) nomenclature of IUBMB. enzyme, metabolic pathway, protein sequence, protein structure, genome, structure, function, annotation, kinetics, molecular property, occurrence, preparation, application, mutant, variant, pathway, ligand, web service, sequence, substructure, FASEB list is related to: ENZYME
is parent organization of: BRENDA Tissue and Enzyme Source Ontology
European Union SLING 226073;
European Union FELICS 021902 (RII3)
PMID:33211880
PMID:30395242
PMID:28438579
PMID:27924025
PMID:25378310
PMID:23203881
PMID:21062828
PMID:14681450
PMID:12850129
PMID:11796225
PMID:11752250
Free, Freely available, r3d100010616, nif-0000-30222 http://www.brenda-enzymes.info/
https://doi.org/10.17616/R39W42
http://www.brenda.uni-koeln.de/ SCR_002997 Brenda: The Comprehensive Enzyme Information System, BRaunschweig ENzyme Database, Brenda: Enzyme Database, BRENDA: The Comprehensive Enzyme Information System 2026-02-14 02:00:37 402
Ensembl
 
Resource Report
Resource Website
10000+ mentions
Ensembl (RRID:SCR_002344) data or information resource, database Collection of genome databases for vertebrates and other eukaryotic species with DNA and protein sequence search capabilities. Used to automatically annotate genome, integrate this annotation with other available biological data and make data publicly available via web. Ensembl tools include BLAST, BLAT, BioMart and the Variant Effect Predictor (VEP) for all supported species. collection, genome, dataset, database, vertebrate, eukaryotic, DNA, protein, sequence, search, automaticly, annotate, data, bio.tools, FASEB list is used by: NIF Data Federation
is used by: Animal QTLdb
is used by: ChannelPedia
is used by: Blueprint Epigenome
is used by: HmtPhenome
lists: Ensembl Covid-19
is listed by: OMICtools
is listed by: Biositemaps
is listed by: re3data.org
is listed by: LabWorm
is listed by: bio.tools
is listed by: Debian
is listed by: SoftCite
is related to: Ensembl Genomes
is related to: GermOnline
is related to: CandiSNPer
is related to: Human Splicing Finder
is related to: NGS-SNP
is related to: Sanger Mouse Resources Portal
is related to: DECIPHER
is related to: Ensembl Genomes
is related to: PeptideAtlas
is related to: AnimalTFDB
is related to: Bgee: dataBase for Gene Expression Evolution
is related to: FlyMine
is related to: Rat Gene Symbol Tracker
is related to: UniParc at the EBI
is related to: go-db-perl
is related to: UniParc
is related to: g:Profiler
is related to: RIKEN integrated database of mammals
is related to: VBASE2
is related to: p300db
is related to: ShinyGO
has parent organization: European Bioinformatics Institute
has parent organization: Wellcome Trust Sanger Institute; Hinxton; United Kingdom
is parent organization of: Ensembl Metazoa
is parent organization of: Ensembl Variation
is parent organization of: Pre Ensembl
is parent organization of: Variant Effect Predictor
is parent organization of: Ensembl Bacteria
is parent organization of: Ensembl Plants
is parent organization of: Ensembl Fungi
is parent organization of: Ensembl Protists
is parent organization of: Ensembl Genome Browser
works with: Genotate
works with: CellPhoneDB
works with: Open Regulatory Annotation Database
works with: Database of genes related to Repeat Expansion Diseases
works with: TarBase
Wellcome Trust ;
EMBL ;
European Union ;
FP7 ;
FP6 ;
MRC ;
NHGRI ;
BBSRC
PMID:24316576
PMID:23203987
nif-0000-21145, OMICS_01647, biotools:ensembl, r3d100010228 https://bio.tools/ensembl
https://sources.debian.org/src/ensembl/
https://doi.org/10.17616/R39K5B
SCR_002344 ENSEMBL 2026-02-14 02:00:23 11652
Alzheimer Europe
 
Resource Report
Resource Website
1+ mentions
Alzheimer Europe (RRID:SCR_003802) AE nonprofit organization A non-governmental organization aimed at raising awareness of all forms of dementia by creating a common European platform through co-ordination and co-operation between Alzheimer organizations throughout Europe. Alzheimer Europe is also a source of information on all aspects of dementia. is related to: Greek Association of Alzheimers Disease and Related Disorders
is related to: PharmaCog
is related to: EMIF
is parent organization of: PharmaCog
Dementia, Alzheimer's disease European Union ISNI: 0000 0001 0739 010X, Wikidata: Q16827712, nlx_158313, grid.424021.1 https://ror.org/029yy6d70 SCR_003802 2026-02-14 02:00:36 8
Recombinase (cre) Activity
 
Resource Report
Resource Website
10+ mentions
Recombinase (cre) Activity (RRID:SCR_006585) Recombinase Activity data or information resource, database Curated data about all recombinase-containing transgenes and knock-ins developed in mice providing a comprehensive resource delineating known activity patterns and allows users to find relevant mouse resources for their studies. cre, recombinase, transgene, knock-in, allele, expression, activity pattern, mutagenesis, promoter, driver, image, tissue, specificity assay is related to: International Mouse Strain Resource
is related to: CREATE
is related to: JAX Cre Repository
is related to: Allen Institute for Brain Science
is related to: CRE Driver Network
is related to: Pleiades Promoter Project: Genomic Resources Advancing Therapies for Brain Disorders
is related to: EUCOMMTOOLS
has parent organization: Mouse Genome Informatics (MGI)
NCRR RR03 2656;
NICHD HD062499;
European Union HEALTH-F4-2009-223487
SCR_017520, nlx_152803 http://www.creportal.org/ SCR_006585 Cre Portal 2026-02-14 02:06:26 21
Mammalian Degradome Database
 
Resource Report
Resource Website
10+ mentions
Mammalian Degradome Database (RRID:SCR_007624) Degradome Database data or information resource, database A database of human, chimpanzee, mouse, and rat proteases and protease inhibitors, as well as as the growing number of hereditary diseases caused by mutations in protease genes. Analysis of the human and mouse genomes has allowed us to annotate 581 human, 580 chimpanzee, 667 mouse, and 655 rat protease genes. Proteases are classified in five different classes according to their mechanism of catalysis. Proteases are a diverse and important group of enzymes representing >2% of the human, chimpanzee, mouse and rat genomes. This group of enzymes is implicated in numerous physiological processes. The importance of proteases is illustrated by the existence of 99 different hereditary diseases due to mutations in protease genes. Furthermore, proteases have been implicated in multiple human pathologies, including vascular diseases, rheumatoid arthritis, neurodegenerative processes, and cancer. During the last ten years, our laboratory has identified and characterized more than 60 human protease genes. Due to the importance of proteolytic enzymes in human physiology and pathology, we have recently introduced the concept of Degradome, as the complete repertoire of proteases expressed by a tissue or organism. Thanks to the recent completion of the human, chimpanzee, mouse, and rat genome sequencing projects, we were able to analyze and compare for the first time the complete protease repertoire in those mammalian organisms, as well as the complement of protease inhibitor genes. This webpage also contains the Supplementary Material of Human and mouse proteases: a comparative genomic approach Nat Rev Genet (2003) 4: 544-558, Genome sequence of the brown Norway rat yields insights into mammalian evolution Nature (2004) 428: 493-521, A genomic analysis of rat proteases and protease inhibitors Genome Res. (2004) 14: 609-622, and Comparative genomic analysis of human and chimpanzee proteases Genomics (2005) 86: 638-647. degradome, mammalian, protease inhibitor, protease, gene, protease gene, genetic disease, proteolysis, protease structure, ancillary domain, genomic, genome is related to: Ancillary Domains Associated With Human and Mouse Proteases
has parent organization: University of Oviedo; Oviedo; Spain
Disease of proteolysis European Union ;
CancerDegradome-FP6 and FP7 ;
Spanish Ministry of Science and Innovation ;
Fundacion M Botin ;
Fundacion Lilly ;
Obra Social Cajastur
PMID:18776217 nif-0000-02746 SCR_007624 Mammalian Degradome Database 2026-02-14 02:06:37 10
Digital Repository Infrastructure Vision for European Research
 
Resource Report
Resource Website
Digital Repository Infrastructure Vision for European Research (RRID:SCR_002752) DRIVER data or information resource, portal Data infrastructure project that merged with OpenAIRE. Cohesive, robust and flexible, pan-European infrastructure for digital repositories, offering sophisticated services and functionalities for researchers, administrators and the general public. Access the network of freely accessible digital repositories with content across academic disciplines with over 3,500,000 scientific publications, found in journal articles, dissertations, books, lectures, reports, etc., harvested regularly from more than 295 repositories, from 38 countries. DRIVER has established a network of relevant experts and Open Access repositories. DRIVER-II will consolidate these efforts and transform the initial testbed into a fully functional, state-of-the art service, extending the network to a larger confederation of repositories. It aims to optimize the way the e-Infrastructure is used to store knowledge, add value to primary research data and information making secondary research more effective, provide a valuable asset for industry, and help bridging research and education. The objectives of DRIVER-II, the second phase of the project, include efforts to expand, enrich, and strengthen the results of DRIVER, in the following areas: * strategic geographic and community expansion by means of the DRIVER confederation * establish a robust, scalable repository infrastructure accompanied by an open source software package D-Net * broader coverage of content through the use of enhanced publications * advanced end-user functionality to support scientific exploration of complex digital objects * larger outreach and advocacy programs * continued repository support * guidelines for interoperability in the larger European digital library community digital, publication, repository, scholarly information, publication, primary data, educational material, digital repository, infrastructure, interoperability, networking is related to: OpenAIRE
has parent organization: University of Athens; Athens; Greece
European Union contract RI- 212147 Free nif-0000-24122 SCR_002752 2026-02-14 02:05:02 0
Connection-set algebra
 
Resource Report
Resource Website
Connection-set algebra (RRID:SCR_017397) CSA software resource Software tool for description of connectivity in small and large scale neuronal network models. It provides operators to form more complex sets of connections from simpler ones and also provides parameterization of such sets. Can be used as component of neuronal network simulators or other tools. Connectivity, neuronal, network, model, simulator European Union PMID:22437992 Free, Available for download, Freely available SCR_017397 Connection Set Algebra 2026-02-14 02:03:25 0
eVOC
 
Resource Report
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eVOC (RRID:SCR_010704) eVOC data or information resource, ontology, controlled vocabulary THIS RESOURCE IS NO LONGER IN SERVICE, documented May 10, 2017. A pilot effort that has developed a centralized, web-based biospecimen locator that presents biospecimens collected and stored at participating Arizona hospitals and biospecimen banks, which are available for acquisition and use by researchers. Researchers may use this site to browse, search and request biospecimens to use in qualified studies. The development of the ABL was guided by the Arizona Biospecimen Consortium (ABC), a consortium of hospitals and medical centers in the Phoenix area, and is now being piloted by this Consortium under the direction of ABRC. You may browse by type (cells, fluid, molecular, tissue) or disease. Common data elements decided by the ABC Standards Committee, based on data elements on the National Cancer Institute''s (NCI''s) Common Biorepository Model (CBM), are displayed. These describe the minimum set of data elements that the NCI determined were most important for a researcher to see about a biospecimen. The ABL currently does not display information on whether or not clinical data is available to accompany the biospecimens. However, a requester has the ability to solicit clinical data in the request. Once a request is approved, the biospecimen provider will contact the requester to discuss the request (and the requester''s questions) before finalizing the invoice and shipment. The ABL is available to the public to browse. In order to request biospecimens from the ABL, the researcher will be required to submit the requested required information. Upon submission of the information, shipment of the requested biospecimen(s) will be dependent on the scientific and institutional review approval. Account required. Registration is open to everyone., documented September 6, 2016. Set of orthogonal controlled vocabularies that unifies gene expression data by facilitating a link between the genome sequence and expression phenotype information. The system associates labelled target cDNAs for microarray experiments, or cDNA libraries and their associated transcripts with controlled terms in a set of hierarchical vocabularies. eVOC consists of four orthogonal controlled vocabularies suitable for describing the domains of human gene expression data including Anatomical System, Cell Type, Pathology and Developmental Stage. The four core eVOC ontologies provide an appropriate set of detailed human terms that describe the sample source of human experimental material such as cDNA and SAGE libraries. These expression terms are linked to libraries and transcripts allowing the assessment of tissue expression profiles, differential gene expression levels and the physical distribution of expression across the genome. Analysis is currently possible using EST and SAGE data, with microarray data being incorporated. The eVOC data is increasingly being accepted as a standard for describing gene expression and eVOC ontologies are integrated with the Ensembl EnsMart database, the Alternate Transcript Diversity Project and the UniProt Knowledgebase. Several groups are currently working to provide shared development of this resource such that it is of maximum use in unifying transcript expression information. mouse, mapping, cdna, development, microarray, expression, expressed sequence, anatomical system, cell type, developmental stage, experimental technique, microarray platform, pathology, pooling, tissue preparation, treatment, gene expression, genome sequence, expression phenotype, genome, sequence, phenotype, anatomical system, cell type, pathology, anatomy is related to: OBO
is related to: Bgee: dataBase for Gene Expression Evolution
has parent organization: University of the Western Cape; Bellville; South Africa
South African National Research Foundation ;
European Union ;
Wellcome Trust ;
South African Department of Arts Culture Science and Technology 32146
PMID:12799354 THIS RESOURCE IS NO LONGER IN SERVICE nlx_84448 SCR_010704 Expressed Sequence Annotation for Humans, eVOC (Expressed Sequence Annotation for Humans), eVOC Ontologies, eVOContology.org 2026-02-14 02:01:48 4

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