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https://www.niddk.nih.gov/research-funding/research-programs/digestive-disease-centers

Center of collaborating research centers working on the research of digestive and liver-related diseases. Each center focuses on etiology, treatment, and prevention of digestive and/or liver diseases.

Proper citation: Digestive Disease Centers (RRID:SCR_015212) Copy   

•   Source: SciCrunch Registry

https://case.edu/medicine/cddrcc/

Center that is focused on what produces the digestive diseases that affect millions of people in the U.S., such as inflammatory bowel disease, hepatitis, metabolic syndromes and obesity.

Proper citation: Cleveland Digestive Diseases Research Core Center (RRID:SCR_015210) Copy   

•   Source: SciCrunch Registry

https://ddrcc.wustl.edu/

Research center whose purpose is to advance research in digestive disease with a focus on interactions between host and environment. It provides research resources to basic and translational investigators through various core facilities.

Proper citation: Washington University Digestive Diseases Research Core Center (RRID:SCR_015252) Copy   

•   Source: SciCrunch Registry

http://www.med.unc.edu/cgibd/cores/gnotobiotic

Core facility that supports animal model and basic research projects of CGIBD investigators. Investigators use this resource to examine physiologic and pathophysiologic differences in germ-free, gnotobiotic, and specific pathogen free colonized mice of various genetic backgrounds.

Proper citation: University of North Carolina Center for Gastrointestinal Biology and Disease Gnotobiotic Core (RRID:SCR_015615) Copy   

•   Source: SciCrunch Registry

http://www.med.upenn.edu/molecular/

Center that aims to unite investigators with interests in digestive, liver and pancreatic physiology and disease in the exploration of creative experimental approaches. The scientific focus of the Center revolves around the molecular controls of cellular growth and differentiation in the digestive tract, liver and pancreas with the goal of achieving a new level of integration in biology, pathobiology, and therapy.

Proper citation: University of Pennsylvania Center for Molecular Studies in Digestive and Liver Diseases (RRID:SCR_015617) Copy   

•   Source: SciCrunch Registry

http://www.jhugicc.org

Center that aims to advance basic science and translational digestive diseases research at the Johns Hopkins University School of Medicine. Its goal is to improve the health of patients with the broad spectrum of gastrointestinal and hepatic disorders.

Proper citation: Hopkins Conte Digestive Diseases Basic and Translational Research Core Center (RRID:SCR_015589) Copy   

•   Source: SciCrunch Registry

http://www.med.upenn.edu/genetics/tcmf/

Core facility that provides a centralized service to efficiently produce genetically altered mice for basic research, resulting in reduction in effort and cost to participating investigators.

Proper citation: University of Pennsylvania Center for Molecular Studies in Digestive and Liver Diseases Genetically-Modified Mouse Core (RRID:SCR_015622) Copy   

•   Source: SciCrunch Registry

http://www.jhugicc.org/GIConteCenter/pages/cores/translationalResearchEnhancementCore.html

Core facility whose services include establishing Best Practices (BP) and uniform Standard Operating Procedures (SOPs) for the collection, annotation, processing, storage, management, distribution, and ethical use of human specimens, and to provide access to specimens by investigators as well as patient identification, patient recruitment, facilitation of patient trials, translational research and basic research through creation of a patient registry and database.

Proper citation: Hopkins Conte Digestive Diseases Basic and Translational Research Core Center Translational Research Enhancement Core (RRID:SCR_015594) Copy   

•   Source: SciCrunch Registry

http://www.med.unc.edu/cgibd

Center at UNC Chapel Hill and North Carolina State University for collaborative GI research. Its mission is to promote and enhance multidisciplinary digestive disease research.

Proper citation: University of North Carolina Center for Gastrointestinal Biology and Disease (RRID:SCR_015612) Copy   

•   Source: SciCrunch Registry

http://www.med.upenn.edu/molecular/core_culture.shtml

Core facility that maintains a centralized repository of cells and reagents pertinent to digestive, liver and pancreatic disease research. It also provides training for labs in new cell culture (2D and 3D) techniques.

Proper citation: University of Pennsylvania Center for Molecular Studies in Digestive and Liver Diseases Cell Culture Core (RRID:SCR_015621) Copy   

•   Source: SciCrunch Registry

http://www.uchicagoddrcc.org/research-cores/integrated-translational-research-core

Core that serves as both a central repository for all the samples and data shared by the other cores and a catalyst for interdisciplinary research.

Proper citation: University of Chicago Digestive Diseases Research Core Center Integrated Translational Research Core (RRID:SCR_015606) Copy   

•   Source: SciCrunch Registry

http://www.med.unc.edu/microbiome

Core facility that provides the research community with the facilities and the expertise to characterize complex microbial communities from different environments.Services offered by the Core include metagenomics methods to determine the composition and function of microbial communities using amplicon, Whole Genome Shotgun (WGS) and RNA sequencing, and traditional and high-throughput quantitative (q)PCR.

Proper citation: University of North Carolina Center for Gastrointestinal Biology and Disease Microbiome Core (RRID:SCR_012644) Copy   

•   Source: SciCrunch Registry

http://www.cure.med.ucla.edu/cores/animal-models

Core that provides in vivo characterization of normal and pathophysiological mechanisms of hormonal and neural regulation of gastrointestinal (GI) function and brain-gut interactions in rodents to members and associate members of the CURE: DDRCC.

Proper citation: CURE - Digestive Diseases Research Center Animal Models Core (RRID:SCR_015217) Copy   

•   Source: SciCrunch Registry

https://www.bcm.edu/research/centers/digestive-disease/core-facilities/administrative

Core that provides governance, financial and operational management, and strategic planning functions for the DDC. This core is also responsible for coordinating the annual Pilot Feasibility Awards program, as well as the weekly GI Research Forum and the annual Frontiers in Digestive Medicine Symposium.

Proper citation: Texas Medical Center Digestive Diseases Center Administrative Core (RRID:SCR_015222) Copy   

•   Source: SciCrunch Registry

https://ww2.mc.vanderbilt.edu/DDRC/6916

Core that aims to further digestive disease research by providing services including identification of oxidized lipids by GC/MS and HR-LC/MS, proteomics for identification and characterization of proteins by MudPIT and LC-MS/MS techniques, quantification of protein expression by LC-MS/MS, interpretation and analysis of mass spectrometry data, and quantification of trace elements in physiologic fluids by ICP-MS.

Proper citation: Vanderbilt Digestive Disease Research Center Bioanalytical Mass Spectrometry and Proteomics Core (RRID:SCR_015223) Copy   

•   Source: SciCrunch Registry

https://www.cincinnatichildrens.org/research/divisions/d/dhc/cores/clinical

Core that is meant to provide members with biostatistical support and the infrastructure to execute disease-based clinical research. Its services include advising on research designs, including project implementation and data collection methods, guidance on appropriate statistical methods based on study design, training and access to REDCap (Research Electronic Data Capture) for research studies, and reviewing REDCap Data Base Structure.

Proper citation: Cincinnati Digestive Health Center Clinical Component-Data Analysis and Management (RRID:SCR_015200) Copy   

•   Source: SciCrunch Registry

http://www.cure.med.ucla.edu/cores/molecular-vector-peptidomics

Core whose aim is to promote and facilitate basic and translational GI research. Its services include consultation and troubleshooting in techniques for efficient gene delivery, as well as cloning and functional protein expression in mammalian cells in vitro and in vivo and consultation and to perform customized gene expression profiling, cytological phenotype profiling, and high-throughput molecular screening studies by utilizing high-throughput and highly automated robotic systems.

Proper citation: CURE - Digestive Diseases Research Center Molecular Biology and Peptidomics Core (RRID:SCR_015213) Copy   

•   Source: SciCrunch Registry

https://ddrcc.wustl.edu/scientific-cores/biobank-core/

Core facility that collects and provides specimens and longitudinal clinical data from patients with digestive diseases. Specimens collected and processed by the core currently include blood, surgical resections, endoscopic biopsies, and stool. Clinical information is stored in a database and linked to specimens and data obtained from these specimens.

Proper citation: Washington University Digestive Diseases Research Core Center Biobank Core (RRID:SCR_015256) Copy   

•   Source: SciCrunch Registry

https://ddrcc.wustl.edu/scientific-cores/administrative-resource-access-core/

Core facility which provides DDRCC members facilitated access to technology and assistance for genetic profiling of clinical and experimental samples.

Proper citation: Washington University Digestive Diseases Research Core Center Administrative and Resource Access Core (RRID:SCR_015253) Copy   

•   Source: SciCrunch Registry

https://ddrcc.wustl.edu/scientific-cores/advanced-imaging-tissue-analysis-core/

Core facility which provides comprehensive histologic and immunohistochemical support, advanced microscopic imaging and image analysis services to digestive disease researchers. The Tissue Analysis Component performs animal and human tissue embedding, sectioning, routine and special staining, and immunohistochemical analyses, and provides training in all services while the Advanced Image Analysis Component provides access to and training in routine light, fluorescent and inverted fluorescent microscopy and quantitative image analysis.

Proper citation: Washington University Digestive Diseases Research Core Center Advanced Imaging and Tissue Analysis Core (RRID:SCR_015254) Copy   

•   Source: SciCrunch Registry