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http://www.scienceexchange.com/facilities/university-of-colorado-denver

THIS RESOURCE IS NO LONGER IN SERVICE. Documented on October 30,2023. Portal, Core facility

Proper citation: University of Colorado Denver Labs and Facilities (RRID:SCR_012175) Copy   

•   Source: SciCrunch Registry

http://www.scienceexchange.com/facilities/transgenic-and-gene-targeting-core

THIS RESOURCE IS NO LONGER IN SERVICE. Documented on April 22,2024. Transgenic and Gene Targeting Core is a full-service facility designed to assist you in generating genetically engineered mouse models for biomedical research. Our services include gene targeting in embryonic stem cells, the generation of ES cell-derived knockout and knockin mice, transgenic mice (conventional and BAC transgenic mice) and the cryo-preservation of mouse lines. The latter service is of particular importance for investigators that have long-term projects with non-commercial mouse lines. Changes in the genetic make-up of your mouse lines that occur spontaneously over time (gene drift) and disease outbreaks can significantly affect the outcome of your research. It is therefore advisable to preserve your mouse lines, providing you with a backup of your valuable research tools. We currently offer both embryo cryopreservation as well as sperm cryopreservation for this purpose.

Proper citation: CU Denver Transgenic and Gene Targeting Core (RRID:SCR_012177) Copy   

•   Source: SciCrunch Registry

http://www.mmc.edu/research/centers/research-centers/metrc/core-facilities.html

Core facility that aids investigators and trainees with high performance computation in proteomics, as well as other omics type applications needing efficient analysis of large-scale biological data sets. The ability to incorporate proteomics into translational and clinical biomedical research is critical for the discovery of therapeutic interventions and high fidelity biomarkers of disease and response to therapy. The Core provides state-of-the-art services, training, and bioinformatics-driven data analysis to the Meharry translational research community.

Proper citation: Meharry Proteomics Core (RRID:SCR_012179) Copy   

•   Source: SciCrunch Registry

https://www.monash.edu/researchinfrastructure/micromon

Provides complete sequencing and data analysis service based around second generation Illumina Genome Analyzer (GAIIx) and Illumina MiSeq sequencing platform. They also offer Agilent Bioanalyzer RNA and DNA analysis, Covaris focussed acoustic shearing of nucleic acids and tissues, qPCR assay design, execution and analysis, oligonucleotide synthesis and capillary electrophoresis (CE/Sanger) sequencing. Offers expertise in advanced DNA and RNA technologies.

Proper citation: Monash University Micromon Core Facility (RRID:SCR_012170) Copy   

•   Source: SciCrunch Registry

http://www.scienceexchange.com/facilities/yale-pathology-tissue-services

THIS RESOURCE IS NO LONGER IN SERVICE. Documented on April 15,2024. Mission- Developmental Histology The mission of the Developmental Histology unit is to provide 1. Timely high quality histology services to the Yale community 2. Access to tissue services from Yale Pathology archives 3. To maximize the value of the resources in the Yale Pathology Tissue Archive. 4. To provide Tissue Microarrays to assess multiple tissue samples Mission- Yale Pathology Tissue Services To provide the maximum amount and quality of human tissue for research at Yale University without impacting diagnostic quality, accuracy and safety in anatomic pathology.

Proper citation: Yale Pathology Tissue Services (RRID:SCR_012290) Copy   

•   Source: SciCrunch Registry

https://lsom.uthscsa.edu/dcsa/research/cores-facilities/optical-imaging/

Service resource which makes imaging technology available to investigators on UTHSCSA campus and neighboring scientific community. Core Optical Imaging Facility offers access to technology for imaging of living cells, tissues, and animals, consultation, education and assistance regarding theory and application of optical imaging techniques, technical advice on specimen preparation techniques and probe selection.

Proper citation: Texas University Health Science Center at San Antonio Long School of Medicine Department of Cell Systems and Anatomy Optical Imaging Core Facility (RRID:SCR_012171) Copy   

•   Source: SciCrunch Registry

http://www.scienceexchange.com/facilities/cardiovascular-physiology-core-facility

The Cardiovascular Physiology Core Facility provides University of Wisconsin (UW) and non-UW researchers with a central resource for creating and studying animal models of disease on a fee-for-service basis. While the central focus of the facility is cardiovascular research, the techniques employed are often useful to investigators in other fields. Currently, the facility is conducting studies into diabetes, bone growth, drug toxicology, and gene therapy in liver and skeletal muscle, as well as cardiovascular disease. One of the most popular services provided by the facility is evaluation of the cardiovascular phenotype of transgenic mice.

Proper citation: UW-Madison Cardiovascular Physiology Core Facility (RRID:SCR_012214) Copy   

•   Source: SciCrunch Registry

http://www.scienceexchange.com/facilities/afm-imaging-group-k-state

We specialize in atomic force microscopy (AFM). We offer: 1. Various AFM imaging assays in air, water, and biological buffers. 2. Single molecule force spectroscopy (FX-AFM and FC-AFM) on proteins and other biomolecules. 3. Hot-tip AFM surface modifications and imaging.

Proper citation: KSU AFM Imaging Group (RRID:SCR_012216) Copy   

•   Source: SciCrunch Registry

http://www.scienceexchange.com/facilities/proteomics-shared-resource-facility-brown

THIS RESOURCE IS NO LONGER IN SERVICE. Documented on April 25,2024. Proteomics Shared Resource Facility's mission is to provide well-maintained, state-of-the-art instrumentation and fundamental proteomics expertise to the Brown University and Rhode Island-EPSCoR scientific communities. It aims to be a focal point of intellectual activity in proteomics by enabling nationally recognized proteomics research within Rhode Island. As an NSF EPSCoR funded laboratory, the Proteomics Facility has a broadly-inclusive philosophy to ensure rapid and equal access to the facility's services for the entire Rhode Island research community. In addition to the acquisition of instrumentation, the Proteomics Core Facility will undertake the training of research in emerging proteomic techniques, a component that is essential to maintaining a productive and professional level of service. The Proteomics Facility has a strong commitment to be at the leading edge of current and developing technologies and provides consultation on their application.

Proper citation: Brown Proteomics Shared Resource Facility (RRID:SCR_012219) Copy   

•   Source: SciCrunch Registry

http://www.scienceexchange.com/facilities/high-throughput-and-high-content-screening-core-facility

The High Throughput and High Content Screening (HTS/HCS) Core Facility specializes in chemical biology as it relates to drug discovery, biological probe discovery, and phenotypic characterization of small-molecule effects on cellular systems. In addition to housing the instrumentation and robotics required for traditional HTS, the Core houses a cutting-edge High Content image-based system for next-generation small-molecule discovery research and analysis in fixed or live cells and cellular systems.

Proper citation: CU Denver High Throughput and High Content Screening Core Facility (RRID:SCR_012218) Copy   

•   Source: SciCrunch Registry

http://www.scienceexchange.com/facilities/dna-analysis-facility-yale

We are an academic Core Facility that supports the applications of DNA Sequencing and Fragment Analysis of Microsatellites and AFLP''''s. Our Facility was founded in 2003 and expanded in 2005 with funds from NSF Instrumentation Development Grant (#0500993). In 2008 a generous gift from the Yale Provost allowed us to upgrade our Applied Biosystems Genetic Analyzer from a 48 to a 96-capillary. In 2010, with funds from NIH Equipment Grant (1S10RR025478-01) we upgraded additional equipment to ensure that we are a an efficient throughput Core. We are housed in the Yale Institute for Biospheric Studies Molecular Systematics and Conservation Genetics Center both under the Direction of Dr. Adalgisa Caccone. The presence of our Core within this setting enhances training within the MSCG Center by allowing students to obtain genetic information from large data sets in a time frame that is appropriate to their academic schedules, and to do so within the budget available for training. Our services are utilized by over 600 users from Yale, other academic institutions and private companies from across the United States and around the world. By promoting access to our equipment we enhance cost effectiveness, reducing idle time and avoid wasting consumables. This in turn allows us to reduce rates and have our services available to users that could otherwise not afford it. While our user base continues to expand our focus remains the same: to offer high quality services at prices affordable to small and medium sized laboratories.

Proper citation: Yale DNA Analysis Facility (RRID:SCR_012187) Copy   

•   Source: SciCrunch Registry

http://www.scienceexchange.com/facilities/integrated-technology-enterprise-inc

THIS RESOURCE IS NO LONGER IN SERVICE. Documented on October 30,2023. We will design and produce DNA constructs for any purpose: Mutations/Deletions Knockout/Transgenic constructs Epitope tags & Fusion proteins Protein expression constructs Viral gene delivery constructs RNAi & related constructs Cost is generally about $300 per construct Turnaround time usually 5 business days

Proper citation: Integrated Technology Enterprise Inc (RRID:SCR_012186) Copy   

•   Source: SciCrunch Registry

http://www.scienceexchange.com/facilities/electron-microscopy-and-histology-core-facility-cornell

THIS RESOURCE IS NO LONGER IN SERVICE. Documented on August 8,2025. The EM & H Core Facility functions as a merger of the facility at WCMC and the Analytical Microscopy Facility at HSS. The microscopes are located at WCMC in the Department of Cell & Developmental Biology. The HSS facility staff performs the TEM specimen preparation for their clients and then comes to WCMC to use the TEM. SEM sample preps for both client groups may be performed in the facility at WCMC.

Proper citation: WCMC Electron Microscopy and Histology Core Facility (RRID:SCR_012222) Copy   

•   Source: SciCrunch Registry

http://www.scienceexchange.com/facilities/drug-discovery-development-and-delivery-core

The Drug Discovery, Development and Delivery (D4) Core provides investigators with access to technological expertise enabling biochemical (100,000+ compounds) and siRNA library screening. We have expertise in development and screening, in both biochemical and cell-based assays. Our mission is to work with investigators to unlock the potential to discover chemical agents that affect cellular targets involved in human diseases.

Proper citation: Penn State Drug Discovery Development and Delivery Core (RRID:SCR_012221) Copy   

•   Source: SciCrunch Registry

http://www.scienceexchange.com/facilities/center-for-protease-research-ndsu

We specialize in the synthesis of small molecules for biological applications and variety of analytical services. The facility works primarily with investigators from Center for Protease Research (CPR). However, we have always extended our services to neighboring institutions and other places all across US when possible. The facility enjoys a successful track record of achievements through service, collaborations, and interdisciplinary interactions.

Proper citation: NDSU Center for Protease Research (RRID:SCR_012223) Copy   

•   Source: SciCrunch Registry

http://www.scienceexchange.com/facilities/akesogen-inc

THIS RESOURCE IS NO LONGER IN SERVICE. Documented on October 30, 2023. AKESOgen is a biomarker, genomics and pharmacogenomics contract research organization that services the academic, pharmaceutical, biotechnology and agricultural sectors. AKESOgen performs biomarker profiling and genomics services utilizing different types of markers (e.g. DNA, RNA, methylation) for the R&D market. AKESOgen establishes and validates biomarkers in the Clinical Trials arena. AKESOgen provides expertise in biobanking. AKESOgen is CLIA certified.

Proper citation: AKESOgen Inc. (RRID:SCR_012180) Copy   

•   Source: SciCrunch Registry

https://www.richmanchemical.com/custom-synthesis/?gclid=Cj0KCQjwqP2pBhDMARIsAJQ0Czp_deoOcbt7aBksAjDKz7wAtJ05S7UicyoFk9d0pH7Tmz4h21cw1OEaAl3cEALw_wcB

Richman Chemical offers a full range of custom synthesis and manufacturing services to life science and chemical industries. Our technical capabilities include: complex multi-step organic synthesis, emulsion or solution polymerization, inorganic custom synthesis (including organometallics), electronic chemicals, stereochemically pure compounds For our pharmaceutical clients, we also provide drug product formulation, compounding, and packaging.

Proper citation: Richman Chemical (RRID:SCR_012183) Copy   

•   Source: SciCrunch Registry

http://www.scienceexchange.com/facilities/molecule-inc

THIS RESOURCE IS NO LONGER IN SERVICE. Documented on October 30,2023. Molecule serves the needs of your businesses, both large and small. We are based in Silicon Valley with local and international labs. We are a team of experts who have worked for world-class companies over 2 decades and provide service in a wide range of chemistry, formulation and new technology development areas of medical device and drug control release products. We provide both contract work and consulting service in wet chemistries (customer design and synthesis) and formulation development. We have spent so much time to accumulate experience so your work can be developed in the shortest amount of time.

Proper citation: Molecule Inc. (RRID:SCR_012182) Copy   

•   Source: SciCrunch Registry

http://www.scienceexchange.com/facilities/protein-production-analysis-core

THIS RESOURCE IS NO LONGER IN SERVICE. Documented on April 25,2024. Sanford-Burnham''s Protein Production Core offers state-of-the-art resources with advanced biochemical engineering and bioprocessing capabilities. Specialized protein production scale-up services (65L bacterial or 25-50L insect/mammalian cell production) include optimization of production runs. Analytical services include measurement of protein-protein and protein-small molecule interactions using a variety of approaches such as surface plasmon resonance and isothermal titration calorimetry. Assistance in experimental design and technical support are also provided by the Core''s knowledgeable staff.

Proper citation: Sanford-Burnham Protein Production and Analysis Core (RRID:SCR_012272) Copy   

•   Source: SciCrunch Registry

http://www.scienceexchange.com/facilities/meg-mcgill

MEG (Magnetoencephalography) is a neuroimaging technology for cognitive and clinical brain research. In a nutshell, MEG measures non-invasively the tiny magnetic fields generated by neuronal currents. A unique asset of MEG imaging is its unrivaled temporal resolution, reaching the millisecond time scale across the entire brain volume. On the clinical side, MEG has been typically indicated for the pre-surgical work-up of severe, drug-resistant epilepsy and the functional pre-surgical mapping of brain tumors. There is however great potential to use MEG as an instrument of choice to investigate other neurological syndromes and neuropsychiatric disorders (e.g., stroke, dementia, movement disorders, depression, etc.). Overall, MEG has strong value in revealing the dynamics of brain activity involved in subject''''s perception, cognition and responses: it has provided unique insight on the time-resolved processes ruling brain functions (resting-state dynamics, language, motor control, visual and auditory perception, etc.) and dysfunctions (movement disorders, tinnitus, chronic pain, dementia, etc.). MEG(at)McGill provides a full-suite of services related to MEG and MEG/EEG studies. This includes a variety of training programs for use of the MEG and related data acquisition and analysis software, Brainstorm.

Proper citation: MEG(at)McGill (RRID:SCR_012277) Copy   

•   Source: SciCrunch Registry