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http://www.scienceexchange.com/facilities/cardiovascular-physiology-core-facility

The Cardiovascular Physiology Core Facility provides University of Wisconsin (UW) and non-UW researchers with a central resource for creating and studying animal models of disease on a fee-for-service basis. While the central focus of the facility is cardiovascular research, the techniques employed are often useful to investigators in other fields. Currently, the facility is conducting studies into diabetes, bone growth, drug toxicology, and gene therapy in liver and skeletal muscle, as well as cardiovascular disease. One of the most popular services provided by the facility is evaluation of the cardiovascular phenotype of transgenic mice.

Proper citation: UW-Madison Cardiovascular Physiology Core Facility (RRID:SCR_012214) Copy   

•   Source: SciCrunch Registry

http://www.scienceexchange.com/facilities/afm-imaging-group-k-state

We specialize in atomic force microscopy (AFM). We offer: 1. Various AFM imaging assays in air, water, and biological buffers. 2. Single molecule force spectroscopy (FX-AFM and FC-AFM) on proteins and other biomolecules. 3. Hot-tip AFM surface modifications and imaging.

Proper citation: KSU AFM Imaging Group (RRID:SCR_012216) Copy   

•   Source: SciCrunch Registry

http://www.scienceexchange.com/facilities/proteomics-shared-resource-facility-brown

THIS RESOURCE IS NO LONGER IN SERVICE. Documented on April 25,2024. Proteomics Shared Resource Facility's mission is to provide well-maintained, state-of-the-art instrumentation and fundamental proteomics expertise to the Brown University and Rhode Island-EPSCoR scientific communities. It aims to be a focal point of intellectual activity in proteomics by enabling nationally recognized proteomics research within Rhode Island. As an NSF EPSCoR funded laboratory, the Proteomics Facility has a broadly-inclusive philosophy to ensure rapid and equal access to the facility's services for the entire Rhode Island research community. In addition to the acquisition of instrumentation, the Proteomics Core Facility will undertake the training of research in emerging proteomic techniques, a component that is essential to maintaining a productive and professional level of service. The Proteomics Facility has a strong commitment to be at the leading edge of current and developing technologies and provides consultation on their application.

Proper citation: Brown Proteomics Shared Resource Facility (RRID:SCR_012219) Copy   

•   Source: SciCrunch Registry

http://www.scienceexchange.com/facilities/high-throughput-and-high-content-screening-core-facility

The High Throughput and High Content Screening (HTS/HCS) Core Facility specializes in chemical biology as it relates to drug discovery, biological probe discovery, and phenotypic characterization of small-molecule effects on cellular systems. In addition to housing the instrumentation and robotics required for traditional HTS, the Core houses a cutting-edge High Content image-based system for next-generation small-molecule discovery research and analysis in fixed or live cells and cellular systems.

Proper citation: CU Denver High Throughput and High Content Screening Core Facility (RRID:SCR_012218) Copy   

•   Source: SciCrunch Registry

http://www.scienceexchange.com/facilities/dna-analysis-facility-yale

We are an academic Core Facility that supports the applications of DNA Sequencing and Fragment Analysis of Microsatellites and AFLP''''s. Our Facility was founded in 2003 and expanded in 2005 with funds from NSF Instrumentation Development Grant (#0500993). In 2008 a generous gift from the Yale Provost allowed us to upgrade our Applied Biosystems Genetic Analyzer from a 48 to a 96-capillary. In 2010, with funds from NIH Equipment Grant (1S10RR025478-01) we upgraded additional equipment to ensure that we are a an efficient throughput Core. We are housed in the Yale Institute for Biospheric Studies Molecular Systematics and Conservation Genetics Center both under the Direction of Dr. Adalgisa Caccone. The presence of our Core within this setting enhances training within the MSCG Center by allowing students to obtain genetic information from large data sets in a time frame that is appropriate to their academic schedules, and to do so within the budget available for training. Our services are utilized by over 600 users from Yale, other academic institutions and private companies from across the United States and around the world. By promoting access to our equipment we enhance cost effectiveness, reducing idle time and avoid wasting consumables. This in turn allows us to reduce rates and have our services available to users that could otherwise not afford it. While our user base continues to expand our focus remains the same: to offer high quality services at prices affordable to small and medium sized laboratories.

Proper citation: Yale DNA Analysis Facility (RRID:SCR_012187) Copy   

•   Source: SciCrunch Registry

http://www.scienceexchange.com/facilities/electron-microscopy-and-histology-core-facility-cornell

THIS RESOURCE IS NO LONGER IN SERVICE. Documented on August 8,2025. The EM & H Core Facility functions as a merger of the facility at WCMC and the Analytical Microscopy Facility at HSS. The microscopes are located at WCMC in the Department of Cell & Developmental Biology. The HSS facility staff performs the TEM specimen preparation for their clients and then comes to WCMC to use the TEM. SEM sample preps for both client groups may be performed in the facility at WCMC.

Proper citation: WCMC Electron Microscopy and Histology Core Facility (RRID:SCR_012222) Copy   

•   Source: SciCrunch Registry

http://www.scienceexchange.com/facilities/drug-discovery-development-and-delivery-core

The Drug Discovery, Development and Delivery (D4) Core provides investigators with access to technological expertise enabling biochemical (100,000+ compounds) and siRNA library screening. We have expertise in development and screening, in both biochemical and cell-based assays. Our mission is to work with investigators to unlock the potential to discover chemical agents that affect cellular targets involved in human diseases.

Proper citation: Penn State Drug Discovery Development and Delivery Core (RRID:SCR_012221) Copy   

•   Source: SciCrunch Registry

http://www.scienceexchange.com/facilities/center-for-protease-research-ndsu

We specialize in the synthesis of small molecules for biological applications and variety of analytical services. The facility works primarily with investigators from Center for Protease Research (CPR). However, we have always extended our services to neighboring institutions and other places all across US when possible. The facility enjoys a successful track record of achievements through service, collaborations, and interdisciplinary interactions.

Proper citation: NDSU Center for Protease Research (RRID:SCR_012223) Copy   

•   Source: SciCrunch Registry

http://www.scienceexchange.com/facilities/next-generation-sequencing-ngs-core

THIS RESOURCE IS NO LONGER IN SERVICE. Documented on May 15,2024. Laboratory: The Institute for Genomics and Systems Biology''''s Next Generation Sequencing Core (IGSB-NGS) is a state-of-the-art facility for ultra-high throughput sequencing. The core was established in 2007 at Argonne National Laboratory and is housed in Argonne''''s Computing, Environment and Life Sciences (CELS) directorate, providing world class computation power, software, and expertise critical to the acquisition, analysis, and interpretation of the unprecedented volume of genetic information being generated on next generation DNA sequencing platforms. The core provides resources and services to Argonne National Laboratory users, University of Chicago users, and to the broader scientific community. NGS is involved in a broad range of scientific research from the sequencing of metagenomic samples to both 16S and 18S rRNA amplicon sequencing for microbial community analysis using next generation sequencing. The NGS laboratory space at Argonne is approximately 1,200 square feet and is supplemented by 140 square feet of office space for the technical director, Ms. Sarah Owens, as well as two additional 140 square foot spaces for technicians. Equipment: The NGS maintains the following workflows: Illumina HiSeq2000 and MiSeq next generation DNA sequencing. The Illumina HiSeq2000 generates over 6 billion reads at 150 bp in length per read resulting in over 600 Gb worth of data across sixteen lanes available per run. The Illumina MiSeq generates over 24 million reads at 150 bp in length per read resulting in over 4.5 Gb worth of data available per run (over a single lane). Applications on both the Illumina HiSeq2000 and MiSeq include: shotgun metagenome sequencing; rRNA-based amplicon library sequencing; and genome sequencing and resequencing. All major equipment is housed within the main laboratory space including three 96-well PCR machines (Applied Biosystems), water baths, analytical balances, refrigerator/freezers (including a large-capacity -80 degree C freezer), incubators, and high and low speed centrifuges (table-top and floor models). Basic equipment and supplies for all advanced molecular techniques (deionized water (Millipore Milli-Q Advantage A10 system), multiple electrophoresis units and digital photographic documentation system) are housed here including equipment for high precision quantitation of nucleic acids (Agilent Bioanalyzer, NanoDrop, and Invitrogen Qubit). The facility also has a Covaris for sample shearing. Any additional equipment needed is located in or near by the NGS laboratory space including a real-time PCR machine (Roche LightCycler 480 with capabilities for both 96-well and 384-well plates) and a liquid handler, the Eppendorf epMotion 5075 robot. Some equipment (autoclaves, ice machine) is located in a common equipment room. Various instruments and methods have been implemented in the NGS''''s standard procedures to maximize quality. These include the use of the Roche Lightcycler 480 II, Agilent Bioanalyzer 2100, Invitrogen Qubit Fluorometer, and barcoding of libraries destined for sequencing. (The latter allows for a test sequencing run of each library to be performed to optimize sequencing lane loading density prior to each library''''s final sequencing run). Personnel overview. NGS operations are managed by Technical Director Sarah Owens. Ms. Owens has a Masters in Molecular Biology and Genetics, and 2 years experience working in high throughput facilities, with over 6 years of molecular biology experience. Ms. Owens was instrumental in trouble-shooting the application of rRNA-based amplicon sequencing for the Illumina HiSeq2000 and MiSeq, developing reproducible protocols in collaboration with Illumina. Under the guidance of the Technical Director, the NGS team helps users to determine the most efficient and cost effective approach to meet their research needs.

Proper citation: UChicago IGSB Next Generation Sequencing Core (RRID:SCR_011063) Copy   

•   Source: SciCrunch Registry

http://www.scienceexchange.com/facilities/photonics-research-centre

THIS RESOURCE IS NO LONGER IN SERVICE. Documented on May 2,2024. We undertake fundamental and applied research in the general area of lasers and photonics, with particular focus on the following seven frontiers of optical science: astrophotonics; biophotonics; microphotonic optical systems; nano-optics and nanophotonics; photonic sources; optical sensing and imaging; ultrafast laser applications.

Proper citation: Macquarie University Photonics Research Centre (RRID:SCR_011068) Copy   

•   Source: SciCrunch Registry

http://www.med.upenn.edu/genetics/dnaseq/index.shtml

Core facility that provides the following services: Large sequencing project support, Sanger sequencing service, High throughput DNA sequencing, Ion Torrent Personal Genome Machine sequencing, Template preparation and purification, Roche 454 sequencing, Sequence analysis and database search support, Construction of targeting vector for gene targeting, Genotyping and Fragment Analysis service, Molecular biology services, Mouse genotyping, and Ion Personal Genome Machine sequencing data analysis. The DNA Sequencing Facility provides long read, automated Sanger sequencing; microsatellite-based genotyping and fragment analysis; plasmid and BAC DNA preparation and purification; and related molecular biological services including PCR, cloning, sub-cloning, site-directed mutagenesis, and preparation of targeting vectors for gene targeting in mice. Core also provides services and support for analysis and interpretation of sequence data as well as the design of approaches to complex sequencing projects. For the last four years the facility has been providing Roche 454 sequencing service that includes library preparation, emulsion PCR and pyrosequencing for both genomic DNA and amplicons.

Proper citation: University of Pennsylvania Genomics Analysis Core (RRID:SCR_011061) Copy   

•   Source: SciCrunch Registry

https://www.mq.edu.au/research/research-centres-groups-and-facilities/innovative-technologies/centres/mqcqe

Macquarie University has established a new multidisciplinary research centre combining physics, mathematics, computer science, engineering and biochemistry to engage in novel research towards deeping our understanding in quantum science and technology.

Proper citation: Macquarie University MQ Research Centre in Quantum Science and Technology (RRID:SCR_012159) Copy   

•   Source: SciCrunch Registry

http://www.scienceexchange.com/facilities/arc-centre-of-excellence-for-engineered-quantum-systems-equs

The ARC Centre of Excellence for Engineered Quantum Systems seeks to engineer complex, multi-component, quantum systems for new science and new applications. Cross-disciplinary scientific advances will link quantum physics with engineering, chemistry, and biology; and sophisticated technologies will be developed for 21st Century Australian industries. The EQuS collaboration possesses experimental capabilities in all major successful quantum technologies including spins in semiconductors, superconducting circuits, opto- and nano-mechanics, trapped atoms, and quantum photonics.

Proper citation: MQ ARC Centre of Excellence for Engineered Quantum Systems (RRID:SCR_011073) Copy   

•   Source: SciCrunch Registry

http://www.scienceexchange.com/facilities/vcu-nanomaterials-characterization-center-vcu

THIS RESOURCE IS NO LONGER IN SERVICE. Documented on April 15,2024. Nanomaterials Characterization Center at Virginia Commonwealth University is a state of the art 4000 sq. ft. facility located within the new Health and Life Science Engineering Facility. The Center provides an academic structure for students in natural sciences, mathematics, engineering, and medicine to participate in nanoscience and nanotechnology research to acquire the skills necessary to pursue such careers. In the past year, VCU received two National Science Foundation major research instrumentation grants totaling more than $1.6 million to expand its capabilities for research in materials science. Combining these federal awards with state instrumentation grants and private donations, the facility has been able to build a state of the art facility with over $5 million in new equipment. This new equipment will allow faculty and student researchers from both VCU campuses, as well as other universities.

Proper citation: VCU Nanomaterials Characterization Center (RRID:SCR_012162) Copy   

•   Source: SciCrunch Registry

http://www.scienceexchange.com/facilities/fauna-park

Situated on the corner of Culloden Rd and Tallavera Rd, Marsfield and originally farmed as market gardens, the Macquarie University Fauna Park stretches over 11Ha; 3.5Ha of which is protected Sydney Turpentine Ironbark Forest. The area is committed to non-intrusive research, e.g. learning to avoid predation, and other natural animal behaviours. Vertebrates (birds, fish, reptiles) or invertebrates (bees, flies, spiders) are observed in natural settings with minimal disruption to their normal environment. This allows the researchers to verify findings they have documented in the field. Other areas of investigation are water ecology and the competitive abilities of native trees.

Proper citation: Macquarie University Fauna Park (RRID:SCR_011075) Copy   

•   Source: SciCrunch Registry

http://www.scienceexchange.com/facilities/wireless-communications-and-networking-laboratory-wcnl

THIS RESOURCE IS NO LONGER IN SERVICE. Documented on April 15,2024. The Wireless Communications and Networking Laboratory (WCNL) at Macquarie University conducts research into emerging wireless communications and networking technologies.

Proper citation: Macquarie University Wireless Communications and Networking Laboratory (RRID:SCR_011076) Copy   

•   Source: SciCrunch Registry

http://www.scienceexchange.com/facilities/guided-wave-optics-and-photonics-research-group-gwopr

The Guided Wave Optics and Photonics Research group (GWOPR) undertakes teaching, research, and development in the area of guided-wave optics, including integrated optics and optical fibres, specialising in microstructured and nanostructured materials. The group''s research capabilities are broad, but mainly target applications in telecommunications and sensing.

Proper citation: Macquarie University Guided Wave Optics and Photonics Research group (RRID:SCR_011077) Copy   

•   Source: SciCrunch Registry

http://www.scienceexchange.com/facilities/animal-models-core

The UNC Animal Models Core Facility provides the full range of mouse genetic modification services, reagents and related technologies. The Core''s services are available to both UNC and Non-UNC clients. Transgenic (pronuclear injection) animals can be generated in C57BL/6, FVB or C57BL/6 X DBA2 hybrid strains. Services for creating transgenic mice include transgene design, construct generation, isolation of the transgene fragment, pronuclear microinjection, founder genotyping and breeding. The core also offers the full suite of services for BAC (bacterial artificial chromosome) recombineering and microinjection of BAC transgenes. Gene targeting services are available in ES cells from C57BL/6 or 129P2/Ola strains. Other strains available upon request. Gene targeting services include design and cloning of targeting vectors, creating gene-targeted ES cells, blastocyst microinjection of the ES cells to create transmitting chimeras and chimera breeding for germline transmission. The core can also provide Southern blot validation and blastocyst microinjection of ES cells from EUCOMM, KOMP or other consortia. Additional services include Cre- or Flp-mediated excision in ES cells or in vivo, chromosome counting, PCR screening and Southern blotting. Rat model production is also available.

Proper citation: UNC School of Medicine Animal Models Core (RRID:SCR_012167) Copy   

•   Source: SciCrunch Registry

https://www.moffitt.org/research-science/shared-resources/proteomics-and-metabolomics/

Provides instrumentation for proteomics and metabolomics studies, including protein, peptide and metabolite separations, MS instrumentation for protein, peptide and metabolite analysis, and data systems, software, and bioinformatics tools for data archiving and analysis. Proteomics Core performs routine analytical proteomics services, including target discovery, identification and quantitation, and also provides platforms for functional proteomics using variety of strategies for protein separation, sub-proteome enrichment, post-translational modification analysis, and quantitation.

Proper citation: Moffitt Cancer Center Proteomics and Metabolomics Core Facility (RRID:SCR_012168) Copy   

•   Source: SciCrunch Registry

https://www.uclahealth.org/departments/pathology/research-services/translational-pathology-core-laboratory-tpcl

Facility in the UCLA Department of Pathology and Laboratory Medicine and UCLA Jonsson Comprehensive Cancer Center Shared Facility. Provids pathology related services in support of basic, translational and clinical research at UCLA. Provides consultative services to investigators in pathology-related study design, tissue selection, microscopic interpretation, immunohistochemistry, laser capture microdissection, digital image analysis, and IRB-related tissue questions.

Proper citation: University of California at Los Angeles Translational Pathology Core Facility (RRID:SCR_012201) Copy   

•   Source: SciCrunch Registry