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SciCrunch Registry is a curated repository of scientific resources, with a focus on biomedical resources, including tools, databases, and core facilities - visit SciCrunch to register your resource.
Core is a fully automated, high-throughput genomic Center equipped with next generation sequencing and microarray platforms. TCGB provides genomics technologies, comprehensive services, specialized expertise and a wide range of trainings, enabling these services to serve basic science and translational/clinical research. In addition, TCGB provides pre-experiment consultation and post-experiment support, including preparation of grant applications, publications, and strategic planning for additional research steps. TCGB also provides educational training to faculty, staff, and students to raise awareness of new directions and major discoveries in the areas of genomics and bioinformatics.
Proper citation: University of California Los Angeles Technology Center for Genomics and Bioinformatics Core Facility (RRID:SCR_012204) Copy
http://www.scienceexchange.com/facilities/keck-biophysics-facility-northwestern
THIS RESOURCE IS NO LONGER IN SERVICE. Documented on January 31,2025. The award-wining Keck Biophysics Facility at Northwestern University has a comprehensive set of state of the art instruments for biophysical and biochemical characterization of macromolecules and their interactions. We provide staff-service, technical expertise and assistance to investigators and companies in the continental US and Canada. The Facility has 15 years of experience with a broad array of biophysical techniques and has generated over 500 publications in top-tier journals.
Proper citation: Northwestern University Keck Biophysics Facility (RRID:SCR_012203) Copy
http://www.scienceexchange.com/facilities/ips-core
The new iPSC Core generates custom-designed iPSCs from mouse and human cells, including disease-specific human iPSCs. iPSCs from other species are currently under development. The Core is currently using both lentiviral- and sendai viral vector systems to deliver reprogramming factors to cells. Both systems are efficient, with the latter system having the advantage to generate iPSCs with a non-DNA-integrating vector system.
Proper citation: CU Denver iPSC Core (RRID:SCR_012176) Copy
http://www.scienceexchange.com/facilities/university-of-colorado-denver
THIS RESOURCE IS NO LONGER IN SERVICE. Documented on October 30,2023. Portal, Core facility
Proper citation: University of Colorado Denver Labs and Facilities (RRID:SCR_012175) Copy
http://www.scienceexchange.com/facilities/transgenic-and-gene-targeting-core
THIS RESOURCE IS NO LONGER IN SERVICE. Documented on April 22,2024. Transgenic and Gene Targeting Core is a full-service facility designed to assist you in generating genetically engineered mouse models for biomedical research. Our services include gene targeting in embryonic stem cells, the generation of ES cell-derived knockout and knockin mice, transgenic mice (conventional and BAC transgenic mice) and the cryo-preservation of mouse lines. The latter service is of particular importance for investigators that have long-term projects with non-commercial mouse lines. Changes in the genetic make-up of your mouse lines that occur spontaneously over time (gene drift) and disease outbreaks can significantly affect the outcome of your research. It is therefore advisable to preserve your mouse lines, providing you with a backup of your valuable research tools. We currently offer both embryo cryopreservation as well as sperm cryopreservation for this purpose.
Proper citation: CU Denver Transgenic and Gene Targeting Core (RRID:SCR_012177) Copy
http://www.mmc.edu/research/centers/research-centers/metrc/core-facilities.html
Core facility that aids investigators and trainees with high performance computation in proteomics, as well as other omics type applications needing efficient analysis of large-scale biological data sets. The ability to incorporate proteomics into translational and clinical biomedical research is critical for the discovery of therapeutic interventions and high fidelity biomarkers of disease and response to therapy. The Core provides state-of-the-art services, training, and bioinformatics-driven data analysis to the Meharry translational research community.
Proper citation: Meharry Proteomics Core (RRID:SCR_012179) Copy
https://www.monash.edu/researchinfrastructure/micromon
Provides complete sequencing and data analysis service based around second generation Illumina Genome Analyzer (GAIIx) and Illumina MiSeq sequencing platform. They also offer Agilent Bioanalyzer RNA and DNA analysis, Covaris focussed acoustic shearing of nucleic acids and tissues, qPCR assay design, execution and analysis, oligonucleotide synthesis and capillary electrophoresis (CE/Sanger) sequencing. Offers expertise in advanced DNA and RNA technologies.
Proper citation: Monash University Micromon Core Facility (RRID:SCR_012170) Copy
https://lsom.uthscsa.edu/dcsa/research/cores-facilities/optical-imaging/
Service resource which makes imaging technology available to investigators on UTHSCSA campus and neighboring scientific community. Core Optical Imaging Facility offers access to technology for imaging of living cells, tissues, and animals, consultation, education and assistance regarding theory and application of optical imaging techniques, technical advice on specimen preparation techniques and probe selection.
Proper citation: Texas University Health Science Center at San Antonio Long School of Medicine Department of Cell Systems and Anatomy Optical Imaging Core Facility (RRID:SCR_012171) Copy
http://www.scienceexchange.com/facilities/cardiovascular-physiology-core-facility
The Cardiovascular Physiology Core Facility provides University of Wisconsin (UW) and non-UW researchers with a central resource for creating and studying animal models of disease on a fee-for-service basis. While the central focus of the facility is cardiovascular research, the techniques employed are often useful to investigators in other fields. Currently, the facility is conducting studies into diabetes, bone growth, drug toxicology, and gene therapy in liver and skeletal muscle, as well as cardiovascular disease. One of the most popular services provided by the facility is evaluation of the cardiovascular phenotype of transgenic mice.
Proper citation: UW-Madison Cardiovascular Physiology Core Facility (RRID:SCR_012214) Copy
http://www.scienceexchange.com/facilities/afm-imaging-group-k-state
We specialize in atomic force microscopy (AFM). We offer: 1. Various AFM imaging assays in air, water, and biological buffers. 2. Single molecule force spectroscopy (FX-AFM and FC-AFM) on proteins and other biomolecules. 3. Hot-tip AFM surface modifications and imaging.
Proper citation: KSU AFM Imaging Group (RRID:SCR_012216) Copy
http://www.scienceexchange.com/facilities/proteomics-shared-resource-facility-brown
THIS RESOURCE IS NO LONGER IN SERVICE. Documented on April 25,2024. Proteomics Shared Resource Facility's mission is to provide well-maintained, state-of-the-art instrumentation and fundamental proteomics expertise to the Brown University and Rhode Island-EPSCoR scientific communities. It aims to be a focal point of intellectual activity in proteomics by enabling nationally recognized proteomics research within Rhode Island. As an NSF EPSCoR funded laboratory, the Proteomics Facility has a broadly-inclusive philosophy to ensure rapid and equal access to the facility's services for the entire Rhode Island research community. In addition to the acquisition of instrumentation, the Proteomics Core Facility will undertake the training of research in emerging proteomic techniques, a component that is essential to maintaining a productive and professional level of service. The Proteomics Facility has a strong commitment to be at the leading edge of current and developing technologies and provides consultation on their application.
Proper citation: Brown Proteomics Shared Resource Facility (RRID:SCR_012219) Copy
http://www.scienceexchange.com/facilities/high-throughput-and-high-content-screening-core-facility
The High Throughput and High Content Screening (HTS/HCS) Core Facility specializes in chemical biology as it relates to drug discovery, biological probe discovery, and phenotypic characterization of small-molecule effects on cellular systems. In addition to housing the instrumentation and robotics required for traditional HTS, the Core houses a cutting-edge High Content image-based system for next-generation small-molecule discovery research and analysis in fixed or live cells and cellular systems.
Proper citation: CU Denver High Throughput and High Content Screening Core Facility (RRID:SCR_012218) Copy
http://www.scienceexchange.com/facilities/dna-analysis-facility-yale
We are an academic Core Facility that supports the applications of DNA Sequencing and Fragment Analysis of Microsatellites and AFLP''''s. Our Facility was founded in 2003 and expanded in 2005 with funds from NSF Instrumentation Development Grant (#0500993). In 2008 a generous gift from the Yale Provost allowed us to upgrade our Applied Biosystems Genetic Analyzer from a 48 to a 96-capillary. In 2010, with funds from NIH Equipment Grant (1S10RR025478-01) we upgraded additional equipment to ensure that we are a an efficient throughput Core. We are housed in the Yale Institute for Biospheric Studies Molecular Systematics and Conservation Genetics Center both under the Direction of Dr. Adalgisa Caccone. The presence of our Core within this setting enhances training within the MSCG Center by allowing students to obtain genetic information from large data sets in a time frame that is appropriate to their academic schedules, and to do so within the budget available for training. Our services are utilized by over 600 users from Yale, other academic institutions and private companies from across the United States and around the world. By promoting access to our equipment we enhance cost effectiveness, reducing idle time and avoid wasting consumables. This in turn allows us to reduce rates and have our services available to users that could otherwise not afford it. While our user base continues to expand our focus remains the same: to offer high quality services at prices affordable to small and medium sized laboratories.
Proper citation: Yale DNA Analysis Facility (RRID:SCR_012187) Copy
http://www.scienceexchange.com/facilities/electron-microscopy-and-histology-core-facility-cornell
THIS RESOURCE IS NO LONGER IN SERVICE. Documented on August 8,2025. The EM & H Core Facility functions as a merger of the facility at WCMC and the Analytical Microscopy Facility at HSS. The microscopes are located at WCMC in the Department of Cell & Developmental Biology. The HSS facility staff performs the TEM specimen preparation for their clients and then comes to WCMC to use the TEM. SEM sample preps for both client groups may be performed in the facility at WCMC.
Proper citation: WCMC Electron Microscopy and Histology Core Facility (RRID:SCR_012222) Copy
http://www.scienceexchange.com/facilities/drug-discovery-development-and-delivery-core
The Drug Discovery, Development and Delivery (D4) Core provides investigators with access to technological expertise enabling biochemical (100,000+ compounds) and siRNA library screening. We have expertise in development and screening, in both biochemical and cell-based assays. Our mission is to work with investigators to unlock the potential to discover chemical agents that affect cellular targets involved in human diseases.
Proper citation: Penn State Drug Discovery Development and Delivery Core (RRID:SCR_012221) Copy
http://www.scienceexchange.com/facilities/center-for-protease-research-ndsu
We specialize in the synthesis of small molecules for biological applications and variety of analytical services. The facility works primarily with investigators from Center for Protease Research (CPR). However, we have always extended our services to neighboring institutions and other places all across US when possible. The facility enjoys a successful track record of achievements through service, collaborations, and interdisciplinary interactions.
Proper citation: NDSU Center for Protease Research (RRID:SCR_012223) Copy
Macquarie University has established a new multidisciplinary research centre combining physics, mathematics, computer science, engineering and biochemistry to engage in novel research towards deeping our understanding in quantum science and technology.
Proper citation: Macquarie University MQ Research Centre in Quantum Science and Technology (RRID:SCR_012159) Copy
http://www.scienceexchange.com/facilities/vcu-nanomaterials-characterization-center-vcu
THIS RESOURCE IS NO LONGER IN SERVICE. Documented on April 15,2024. Nanomaterials Characterization Center at Virginia Commonwealth University is a state of the art 4000 sq. ft. facility located within the new Health and Life Science Engineering Facility. The Center provides an academic structure for students in natural sciences, mathematics, engineering, and medicine to participate in nanoscience and nanotechnology research to acquire the skills necessary to pursue such careers. In the past year, VCU received two National Science Foundation major research instrumentation grants totaling more than $1.6 million to expand its capabilities for research in materials science. Combining these federal awards with state instrumentation grants and private donations, the facility has been able to build a state of the art facility with over $5 million in new equipment. This new equipment will allow faculty and student researchers from both VCU campuses, as well as other universities.
Proper citation: VCU Nanomaterials Characterization Center (RRID:SCR_012162) Copy
http://www.scienceexchange.com/facilities/animal-models-core
The UNC Animal Models Core Facility provides the full range of mouse genetic modification services, reagents and related technologies. The Core''s services are available to both UNC and Non-UNC clients. Transgenic (pronuclear injection) animals can be generated in C57BL/6, FVB or C57BL/6 X DBA2 hybrid strains. Services for creating transgenic mice include transgene design, construct generation, isolation of the transgene fragment, pronuclear microinjection, founder genotyping and breeding. The core also offers the full suite of services for BAC (bacterial artificial chromosome) recombineering and microinjection of BAC transgenes. Gene targeting services are available in ES cells from C57BL/6 or 129P2/Ola strains. Other strains available upon request. Gene targeting services include design and cloning of targeting vectors, creating gene-targeted ES cells, blastocyst microinjection of the ES cells to create transmitting chimeras and chimera breeding for germline transmission. The core can also provide Southern blot validation and blastocyst microinjection of ES cells from EUCOMM, KOMP or other consortia. Additional services include Cre- or Flp-mediated excision in ES cells or in vivo, chromosome counting, PCR screening and Southern blotting. Rat model production is also available.
Proper citation: UNC School of Medicine Animal Models Core (RRID:SCR_012167) Copy
https://www.moffitt.org/research-science/shared-resources/proteomics-and-metabolomics/
Provides instrumentation for proteomics and metabolomics studies, including protein, peptide and metabolite separations, MS instrumentation for protein, peptide and metabolite analysis, and data systems, software, and bioinformatics tools for data archiving and analysis. Proteomics Core performs routine analytical proteomics services, including target discovery, identification and quantitation, and also provides platforms for functional proteomics using variety of strategies for protein separation, sub-proteome enrichment, post-translational modification analysis, and quantitation.
Proper citation: Moffitt Cancer Center Proteomics and Metabolomics Core Facility (RRID:SCR_012168) Copy
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