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http://hawaii.eagle-i.net/i/0000012b-b257-d364-2f73-b43980000000

The Biostatistics Shared Resource (BSR) provides statistical consultation and support to the research enterprise of the University of Hawai?i Cancer Center. The primary goal of the resource is to improve the quality of the research through sound statistical principles. The resource was established in 1995 and provides access to statistical support to all Center members on all aspects of research. The BSR provides short-term as well as long-term support for research projects. Support is provided to scientists in epidemiology, health behavior and quality of life research, and molecular and clinical oncology. The members of the Shared Resource often serve as co-investigators on epidemiology and cancer prevention and control projects. Consultation is available in the following areas: design, data collection, data analysis, statistical programming, interpretation and dissemination of results, and protocol review. The members of the resource have contributed to the publication of many peer-reviewed manuscripts from Center research projects. In addition, the statisticians work on methodological issues important to the research ongoing at UH Cancer Center. One area of interest is measurement error models that correct for bias in model parameter estimates when the exposure variable is measured with error. The role of dietary intake and sunlight exposure in cancer etiology are of interest at the Center, and these variables are measured with error. Another interest is in how susceptibility genes affect cancer risk, in combination with exposure data. Therefore, statistical techniques for the investigation of genes and lifestyle-gene interactions in cancer models are also studied.

Proper citation: UH Manoa Biostatistics Shared Resources (RRID:SCR_010088) Copy   

•   Source: SciCrunch Registry

http://hawaii.eagle-i.net/i/0000012a-2512-0387-c99c-aef680000000

THIS RESOURCE IS NO LONGER IN SERVICE. Documented on October 30,2023. Core provides access to high speed computer hardware and bioinformatics consultation. Research at the facility includes studying of evolutionary change in emergent dengue viruses associated with increasingly severe epidemics and confirm the impact of these changes in experimental models.

Proper citation: University of Hawaii at Manoa Centers of Biomedical Research Excellence Bioinformatics Core Facility (RRID:SCR_010089) Copy   

•   Source: SciCrunch Registry

http://upr.eagle-i.net/i/0000012a-250a-2ace-43fb-601a80000000

THIS RESOURCE IS NO LONGER IN SERVICE. Documented on January 26,2026. Core facility that provides the following services: Oligonucleotide synthesis service, Automated DNA sequencing, Genotyping analysis service, Analysis of DNA, RNA or proteins, Microarray service. The long-term goal of the Center for Genomics in Health Disparities and Rare Diseases (CGHDRD) is to provide the critical environment that will enable high quality translational and biomedical research in pharmacogenomics, human genetics and genomics, molecular biology. We aim to develop and strengthen a collaborative research environment by providing research infrastructure that supports the focal areas of research at the University of Puerto Rico Medical Sciences Campus (UPR-MSC), which encompass common diseases such as cancer, neurological and cardiovascular disorders as well as rare disorders, by improving the human and physical resources. The Center focuses these initiatives on externally funded, interdisciplinary, collaborative projects which enhance the quality of translational, biomedical and clinical research at the Medical Sciences Campus linked to health disparities and rare disorders in Puerto Rico and nationally. Collaborations with researchers at institutions outside of Puerto Rico or other RCMI institutions, as well as other academic units in the island and in the UPR system are encouraged. The Center provides the necessary expertise to apply high throughput genotyping, expression profiling and sequencing technologies at the UPR-MSC. Specialized technical staff trains researchers at different levels of their scientific careers in supported technologies. Novel DNA and RNA isolation methodologies are applied to a diverse group of organisms and biological samples for nucleic acids sequence analysis in general.

Proper citation: UPR Center for Genomics in Health Disparities and Rare Disorders (RRID:SCR_010122) Copy   

•   Source: SciCrunch Registry

http://uccaribe.eagle-i.net/i/00000135-e488-f75c-a272-8ee780000000

Core facility that provides the following services: Nucleic acid sequencing service, Real-Time PCR services, Cell culture service, Protein quantitation assay, Nucleic acid estimation service, Fusion protein purification and expression service, Transfection service, Site-directed mutagenesis service, Primer design service, Gel electrophoresis service, Polymerase chain reaction service. The Protein and Nucleic Acid Core Facility (PNACF) aids in the transition from classical to molecular analysis of the problems being addressed by faculty members. PNACF focuses on faculty training, seminars, training on specialized molecular biology techniques, protein expression and protein purification and characterization.

Proper citation: UCC Protein and Nucleic Acid Core Facility (RRID:SCR_010080) Copy   

•   Source: SciCrunch Registry

http://hawaii.eagle-i.net/i/0000012b-36a1-152c-2f73-b43980000000

Core facility that provides the following services: Solid state studies service.

Proper citation: UH Manoa NMR Lab (RRID:SCR_010082) Copy   

•   Source: SciCrunch Registry

http://xula.eagle-i.net/i/00000134-ed9a-ccf6-77e4-a45080000000

The Major Instrumentation Core has been established to provide technical services and consumable supplies necessary for the operation and maintenance of a variety of major instruments that support biomedical research at Xavier University. The long term goal of the Major Instrumentation Core is to enhance the overall biomedical research capabilities at Xavier University by making available essential instrument-based platforms for various research projects. To achieve this goal the Major Instrumentation Core has set the following specific aims: 1). support biomedical research projects on campus by providing essential analytical instrumentation, 2). maintain and operate existing instruments, 3). acquire new instruments, and 4). provide technical support for user community of the core.

Proper citation: XULA Major Instrumentation Core (RRID:SCR_010209) Copy   

•   Source: SciCrunch Registry

http://eagle-i.ea.vanderbilt.edu/i/00000139-a1a9-3071-b4bd-8a1180000000

Core facility that provides the following services: Hematology Services, Parasitology Services, Chemistry Analysis Services, Cell Line Testing, Customizable Chemistry Analysis, Phenotyping Services, Infertility evaluation in male mice, Veterinary Pathologist Consultation. Access to consented and de-identified human tissue specimens; Comprehensive, state of the art diagnostic, necropsy and comparative pathology services for animal model systems with specific expertise and focus on mouse models; Research histology including advanced techniques, immunohistochemistry, immunofluorescence, laser capture micro-dissection and tissue micro-array preparation; Access to experts in veterinary and human pathology.

Proper citation: Vanderbilt Translational Pathology Shared Resource (RRID:SCR_010201) Copy   

•   Source: SciCrunch Registry

http://eagle-i.ea.vanderbilt.edu/i/00000139-362c-e975-dacb-da6080000000

The Chemical Synthesis Core was established within the Vanderbilt Institute of Chemical Biology with the goal of supporting the organic and medicinal chemistry needs of investigators. The primary focus of the core is to facilitate biology-orientated projects within the medical center and the university by assisting with the chemistry aspect of the project. The core works independently or in collaboration with the VICB High Throughput Screening Center on the synthesis of literature-cited compounds (including patented ones) as well as full scale lead optimization of a compound.

Proper citation: Vanderbilt Chemical Synthesis Core Laboratory (RRID:SCR_010169) Copy   

•   Source: SciCrunch Registry

http://eagle-i.ea.vanderbilt.edu/i/00000139-1107-96fa-dacb-da6080000000

The current zebrafish facility is composed of approximately 100 research tanks available for short and long-term studies, and a significant expansion project is underway. The facility enables investigator access to the unique advantages of the zebrafish model, which provides hundreds of mutant and transgenic zebrafish with unique properties suited for specific experiments. This core?s essential mission is to provide a reliable mechanism for incorporation and propagation of new and existing zebrafish lines into the core.

Proper citation: Vanderbilt Zebrafish Aquatic Facility (RRID:SCR_010202) Copy   

•   Source: SciCrunch Registry

https://www.wistar.org/resources/genomics-facility/

Core facility that provides the following services: Microarray services, RNA amplification service, ABI 7900 Real-time qPCR service, Capillary DNA sequencing and microsatellite analysis, Illumina HiSeq 2000 sequencing service, Illumina Genome Analyzer services. The Wistar Genomics Facility serves as a hub for consultation and scientific interactions relating to nucleic-acid based methods and provides expertise and support to insure the best possible use of emerging nucleic-acid technologies. In addition to consultation and collaboration with Wistar Cancer Center members, the Facility provides services to the greater scientific community. The establishment of this facility was supported in part by an NCI Cancer Center Support Grant and equipment grants from the Commonwealth of Pennsylvania, The Pew Charitable Trusts and the National Cancer Institute.

Proper citation: Wistar Genomics Core Facility (RRID:SCR_010205) Copy   

•   Source: SciCrunch Registry

https://www.wistar.org/resources/biomedical-research-support-facility/histotechnology/

Core facility that provides the following services: Paraffin sectioning service, Frozen sectioning service, Histology staining services. This facility provides basic histology services. These include fixing, processing and paraffin embedding of all types of tissues for light microscopy (i.e. routine stains, immunohistochemistry or in situ hybridization). Routine hematoxylin and eosin staining as well as special staining is done in the lab. Slides are prepared for immunohistochemistry and in situ and immunohistochemistry. Frozen sectioning is also available. It is advisable to contact the facility about freezing techniques so the best sections can be obtained.

Proper citation: Wistar Histotechnology Core Facility (RRID:SCR_010206) Copy   

•   Source: SciCrunch Registry

https://www.wistar.org/resources/imaging-facility/

Core facility that provides the following services: Live-cell time-lapse microscopy, Low magnification and photomacrography? service, Confocal microscopy service, Two-photon microscopy, Small animal whole body luminescence and fluorescence imaging?, 2, 3, 4, and 5D image analysis, Imaging consultation service, Imaging equipment, image processing, and image analysis training, In-lab microscopy assistance and maintenance service, Imaging Facility instrument access. The Imaging Facility is a shared resource with the primary goal of providing exceptional microscopy and imaging services, as well as individual access to a variety of state-of-the-art imaging resources for members of the Wistar research community. The imaging systems have been designed to be extremely flexible to reflect a broad range of challenging scientific questions and specimens. Each system provides a combination of illumination, optics and image capture options. Diverse subjects ranging from fluorescently tagged live cell cultures and stained tissue sections, to 3D tumor spheroids and low magnification explanted tissues, can be accommodated with available systems. Current equipment includes standard upright and inverted fluorescence microscopes, a customized live-cell time lapse microscope capable of 6D imaging, a laser scanning confocal microscope, a 2-photon microscope designed for in vivo imaging, a small animal, whole body luminescence and fluorescence imager, special low magnification (photomacrography) systems as well as a variety of traditional photographic cameras, lenses and lighting equipment. Users of the facility may be trained for unassisted use of all core assets, or they may elect assisted service with the facility staff performing the imaging. The Imaging staff also provides assistance to researchers with additional aspects of their imaging requirements. Ideal approaches to specimen documentation are often unique to the experiment and the staff can help design the most effective imaging protocols to answer a particular question. On-site assistance is available to help investigators get the most out of their own systems. Image analysis and specialized Photoshop training, creative imaging for journal covers, and guidance on digital imaging ethics help to round out the services available from the facility.

Proper citation: Wistar Imaging Core Facility (RRID:SCR_010207) Copy   

•   Source: SciCrunch Registry

http://eagle-i.ea.vanderbilt.edu/i/00000139-c643-b905-b341-4bb480000000

An Core facility

Proper citation: Vanderbilt Clinical Trials Center (RRID:SCR_010171) Copy   

•   Source: SciCrunch Registry

http://eagle-i.ea.vanderbilt.edu/i/00000139-c637-b593-b341-4bb480000000

The primary mission of the Clinical Trials Shared Resource (CTSR), as identified in the Cancer Center Support Grant (CCSG), is to assist Cancer Center investigators develop, activate and complete scientifically-meritorious clinical trials in an efficient, cost-effective and technically-sound manner.

Proper citation: Vanderbilt Clinical Trials Shared Resource (RRID:SCR_010172) Copy   

•   Source: SciCrunch Registry

http://chgr.mc.vanderbilt.edu/page/computational-genomics-core

THIS RESOURCE IS NO LONGER IN SERVCE, documented January 25, 2019. Core provides software and hardware support for computing activities related to genetics and biology, as well as statistical analysis for human genetics data generated from both microsatellite markers and SNPs. Bioinformatics support, resources, and expertise are available in storing and managing demographic, clinical, genotypic, microarray, proteomic and biospecimen data.

Proper citation: Vanderbilt University Center for Human Genetics Research Computational Genomics Core (RRID:SCR_010173) Copy   

•   Source: SciCrunch Registry

http://eagle-i.ea.vanderbilt.edu/i/00000139-b673-9ac0-b341-4bb480000000

Core facility that provides the following services: Biospecimen acquisition. The Cooperative Human Tissue Network- Western Division at Vanderbilt University Medical Center is one of six institutions throughout the country funded by the National Cancer Institutes to procure and distribute remnant human tissues to biomedical researchers throughout the United States and Canada. CHTN operates through a shared networking system which allows investigators greater access to available research specimens. CHTN offers a variety of preparation and preservation techniques to ensure investigators are receiving the quality specimens needed for research. Remnant tissues are obtained from surgical resections and autopsies and are procured to the specifications of the investigator.

Proper citation: Vanderbilt Cooperative Human Tissue Network (RRID:SCR_010174) Copy   

•   Source: SciCrunch Registry

http://eagle-i.ea.vanderbilt.edu/i/00000139-c646-d984-b341-4bb480000000

BioVU is a research resource providing a View into biology at the level of DNA and other important macromolecules. BioVU has two major components. The first is a repository of DNA samples (extracted from discarded blood samples) that are coded solely by a Research Unique Identifier (RUI) derived from the Medical Record Number (MRN) using a one-way hash function. This is a computer algorithm that creates a transformation of each MRN such that the resulting RUI (which is in this instance is a 512 byte identifier) is unique, and has the property that it is not possible to infer or compute the MRN that generated it. As of early 2009, over 50,000 DNA samples were in the biobank, with new samples being added at the rate of approximately 700 per week.

Proper citation: Vanderbilt DNA Databank (RRID:SCR_010175) Copy   

•   Source: SciCrunch Registry

http://eagle-i.ea.vanderbilt.edu/i/00000139-a249-859f-b4bd-8a1180000000

The Eicosanoid Core Laboratory facility employs mass spectrometry to quantify lipid oxidation products produced in a variety of vascular (and other) disorders including prostaglandins, leukotrienes, isoprostanes, and their urinary metabolites.

Proper citation: Vanderbilt Eicosanoid Core Laboratory (RRID:SCR_010177) Copy   

•   Source: SciCrunch Registry

http://harvard.eagle-i.net/i/0000013e-5708-120e-7db7-114480000000

The Core''s capabilities include six Computer Numerical Control (CNC) milling centers (one of which is a five-axis micro-milling machine), two 3D printers, a waterjet cutter, a laser cutter, and a sinker Electrical Discharge Machining (EDM) tool. The Core has three full time machinists with experience in both industrial and academic machine shops, creating prototypes for varied applications. In addition to fabrication, these experts help researchers during the design phase, enabling development from a simple concept into real prototypes.

Proper citation: Wyss Institute Machine Shop / 3D Prototyping Core (RRID:SCR_010212) Copy   

•   Source: SciCrunch Registry

http://harvard.eagle-i.net/i/00000137-b920-a047-d807-77a880000000

The Wyss Institute Materials Characterization Core is dedicated to promoting leading edge biologically inspired research by providing users with a wide range of state-of-the-art materials characterization equipment and analysis software. These tools help support the characterization of a material?s unique physical, chemical, and mechanical properties. The Materials Characterization Core team provides exceptional hands on training, method development, and technical expertise. We also proactively stride to introduce the latest innovations in materials characterization to the Wyss Institute community and our affiliated partners. Our current techniques include chromatography, mass spectrometry, UV-Vis spectroscopy, particle sizing, quartz crystal microbalance, electrochemical testing, rheology, and nanoindentation.

Proper citation: Wyss Institute Materials Characterization Core (RRID:SCR_010213) Copy   

•   Source: SciCrunch Registry