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SciCrunch Registry is a curated repository of scientific resources, with a focus on biomedical resources, including tools, databases, and core facilities - visit SciCrunch to register your resource.
Core which uses stable isotope flux and metabolite profiling to help formulate and test hypotheses about the metabolic consequences of various changes in gene expression and protein function, in order to guide further integrative systems biology analyses of the underlying mechanisms in diabetes, insulin resistance, obesity, and diabetic complications.
Proper citation: Einstein-Mount Sinai Diabetes Research Center Stable Isotope and Metabolomics Core Facility (RRID:SCR_015071) Copy
https://einsteinmed.edu/centers/diabetes-research/biomedical-cores/animal-physiology/
Core which assists with the in vivo assessment of glucose and fatty acid metabolism, insulin sensitivity and energy homeostasis in mice and rats. It provides tools to understand the behavior and physiology mediating the relationships among diabetes, nutrient sensing, obesity and diabetic cardiovascular complications in rodents.
Proper citation: Einstein-Mount Sinai Diabetes Research Center Animal Physiology Core Facility (RRID:SCR_015076) Copy
http://www.baderc.org/cores/transgenicCore.html
THIS RESOURCE IS NO LONGER IN SERVICE. Documented on July 23,2024.Transgenic core which generates transgenic and gene knockout mouse models relevant to obesity, diabetes and nutrition research. It also provides consultation on all aspects of making transgenic and gene knockout mice.
Proper citation: Boston Area Diabetes Endocrinology Research Center Transgenic (RRID:SCR_015074) Copy
Provides MDRC researchers with expert consultation, training and support for routine and advanced microscopy and image analysis techniques. Services include Consultation and Advice on Microscopy and Immunohistochemistry, Cryosection Service, Confocal Microscopy, Image Analysis, Widefield Light Microscopy,Live Cell Microscopy,Training and Education.
Proper citation: Michigan Diabetes Research Center Microscopy and Image Analysis Core Facility (RRID:SCR_015118) Copy
http://www.hopkinsmedicine.org/diabetes-research-center/research-cores/integrated-physiology.html
THIS RESOURCE IS NO LONGER IN SERVICE. Documented on July 24,2024. Core consisting of several subcores: Ligand Assay and Biomarker Subcore (offers services in Multiplex Assay Detection Systems, Comprehensive Laboratory Animal Monitoring System (CLAMS), and Body Composition), Rodent Physiology and Behavioral Analysis Subcore, and Glucose Metabolism Analysis Subcore (provides services in Dynamic Physiologic Testing).
Proper citation: Johns Hopkins University - University of Maryland Diabetes Research Center Integrated Physiology Core (RRID:SCR_015088) Copy
http://www.med.upenn.edu/idom/drc/cores/metacore.html
Core which aims to develop and validate metabolomic methods and data analysis software and provide high quality routine metabolomic services. Its services include quantitation of selected water-soluble metabolites, fatty acids, and lipids, quantitation of metabolic fluxes using stable isotope tracers, and identification of novel metabolites involved in diabetes pathophysoiology.
Proper citation: Penn Diabetes Research Center Metabolomics Core (RRID:SCR_015122) Copy
https://www.iths.org/resources/directory/listing/drc-human-studies-core-university-of-washington
Core facility that provides specialized technical resources and expertise to enhance the efficiency, productivity and multidisciplinary nature of clinical research performed by Diabetes Research Center (DRC)-affiliated investigators.
Proper citation: University of Washington Diabetes Research Center Human Studies Core Facility (RRID:SCR_015127) Copy
http://depts.washington.edu/diabetes/cell-function-analysis-core/
Core facility that supports the Diabetes Research Center affiliates by offering precise real time functional analysis of intact cells and primary tissue. The Cell Function Analysis Core also provides an islet isolation service, which gives affiliates easy access to primary tissue/cells ex vivo.
Proper citation: University of Washington Diabetes Research Center Cell Function Analysis Core Facility (RRID:SCR_015128) Copy
http://www.hopkinsmedicine.org/diabetes-research-center/research-cores/administrative.html
THIS RESOURCE IS NO LONGER IN SERVICE. Documented on July 24,2024. Core that typically organizes a meeting with the investigator/user and relevant core directors to discuss the different services and tests that the Diabetes Research Center would recommend to the investigator. It also provides support letters for grant proposals submitted by investigators.
Proper citation: Johns Hopkins University - University of Maryland Diabetes Research Center Administrative Core (RRID:SCR_015087) Copy
http://drtc.bsd.uchicago.edu/molecular-biology-and-genetics-core-laboratory-about/
THIS RESOURCE IS NO LONGER IN SERVICE. Documented on November 7,2024. Molecular biology and genetics core which helps independently funded investigators with an interest in diabetes mellitus and other metabolic disorders to clone, sequence and characterize cDNAs and genes of interest. It also provides research tools and expertise to enable investigators to discover how genetic variation in diabetes genes leads to hyperglycemia.
Proper citation: University of Chicago Diabetes Research and Training Center Molecular Biology and Genetics Core Laboratory (RRID:SCR_015129) Copy
https://diabetescenters.org/cores/ucsd-ucla-human-genetics-core
Core provides services such as assistance in the development and successful completion of well-designed genetic studies, establishment and storage of EBV-transformed lymphoblastoid cell lines (LCLs), as well as PAXgene tubes, and specialized (e.g., the exome chip) single nucleotide polymorphism (SNP) testing, candidate gene sequencing, whole exome sequencing (WES), whole genome sequencing (WGS), and large-scale gene methylation analysis.
Proper citation: University of California San Diego - University of California Los Angeles Diabetes Research Center Human Genetics Core Facility (RRID:SCR_015099) Copy
https://joslinresearch.org/drc-cores/Enrichment-Core
THIS RESOURCE IS NO LONGER IN SERVICE. Documented on August 9,2024. Six component core which facilitates the exchange of research information and discussions among investigators, fellows and students within the Joslin Diabetes Center, as well as between Joslin Staff and outside researchers with similar interests.
Proper citation: Joslin Diabetes Center Enrichment Core (RRID:SCR_015094) Copy
http://www.hopkinsmedicine.org/diabetes-research-center/research-cores/gene-editing.html
THIS RESOURCE IS NO LONGER IN SERVICE. Documented on August 9,2024. Core that provides services in Gene Editing Expertise Using CRISPR/CAS9, Conventional Transgenic Mouse Generation, Conventional Knockout, Knock-In Mouse Generation, and Cryopereservation of Sperm, Oocytes and Embryos.
Proper citation: Johns Hopkins University - University of Maryland Diabetes Research Center Gene Editing Core (RRID:SCR_015091) Copy
Core that offers support for data-driven projects related to basic, clinical and translational research, with a particular emphasis on diabetes. The core aims to ensure that researchers take advantage of the most modern and robust methods available in the field of Bioinformatics and Biostatistics.
Proper citation: Joslin Diabetes Center Bioinformatics and Biostatistics Core (RRID:SCR_015092) Copy
THIS RESOURCE IS NO LONGER IN SERVICE. Documented on October 8, 2024. Core with main goal to steer investigators through introductory discovery lipidomics and proteomics experiments toward statistically powered, targeted experiments aimed at measuring biological pathways relevant to diabetes and metabolism.
Proper citation: University of California San Diego - University of California Los Angeles Diabetes Research Center Targeted Pathway Analysis Core Facility (RRID:SCR_015098) Copy
https://diabetescenters.org/cores/ucsd-ucla-transgenic-and-knockout-mouse-core
Core that provides and produces transgenic mice. Services and methodologies include pronuclear microinjection and blastocyst microinjection for creation of new mouse cell lines as well as archival services like embryo and sperm freezing.
Proper citation: University of California San Diego - University of California Los Angeles Diabetes Research Center Transgenic and Knockout Mouse Core Facility (RRID:SCR_015096) Copy
http://www.cure.med.ucla.edu/cores/animal-models
Core that provides in vivo characterization of normal and pathophysiological mechanisms of hormonal and neural regulation of gastrointestinal (GI) function and brain-gut interactions in rodents to members and associate members of the CURE: DDRCC.
Proper citation: CURE - Digestive Diseases Research Center Animal Models Core (RRID:SCR_015217) Copy
http://www.einstein.yu.edu/centers/diabetes-translational-research/latino-network/
Research network dedicated to supporting translation research in diabetes prevention and control. The core has a strong emphasis on sociocultural adaption for Latinos in the U.S and can provide expertise in Latino biopsychosocial research.
Proper citation: New York Regional Center for Diabetes Translation Research Latino Network for Diabetes Translational Research (RRID:SCR_015189) Copy
https://www.bcm.edu/research/centers/digestive-disease/core-facilities/administrative
Core that provides governance, financial and operational management, and strategic planning functions for the DDC. This core is also responsible for coordinating the annual Pilot Feasibility Awards program, as well as the weekly GI Research Forum and the annual Frontiers in Digestive Medicine Symposium.
Proper citation: Texas Medical Center Digestive Diseases Center Administrative Core (RRID:SCR_015222) Copy
https://ww2.mc.vanderbilt.edu/DDRC/6916
Core that aims to further digestive disease research by providing services including identification of oxidized lipids by GC/MS and HR-LC/MS, proteomics for identification and characterization of proteins by MudPIT and LC-MS/MS techniques, quantification of protein expression by LC-MS/MS, interpretation and analysis of mass spectrometry data, and quantification of trace elements in physiologic fluids by ICP-MS.
Proper citation: Vanderbilt Digestive Disease Research Center Bioanalytical Mass Spectrometry and Proteomics Core (RRID:SCR_015223) Copy
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