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http://eagle-i.itmat.upenn.edu/i/00000139-b6a6-e595-9dbb-bb2180000000

Core facility that provides the following services: NBIC instrumentation training, Scanning probe measurement service. The NBIC serves as an incubator for new probes of nanostructure behavior and associated instrumentation development. It is equipped with a suite of scanning probes, opto-electronic/transport tools, and optical probes that are so recently developed as not to be available on commercial instruments. The environment facilitates the development and refinement of new probe-based techniques.

Proper citation: Penn NBIC Probe Facility (RRID:SCR_010023) Copy   

•   Source: SciCrunch Registry

http://eagle-i.itmat.upenn.edu/i/00000138-baad-3af2-9cd7-d7e280000000

Core facility that provides the following services: Behavioral testing training, Behavioral testing consultation service, Neurobehavior Testing Core access, Evaluation of anxiety behavior, Evaluation of circadian activity and rest/activity patterns, Measurement of sleep/wake patterns, Video image analysis of behavioral assays, Tissue harvest and histology prep service, Customized behavior batteries. The Neurobehavior Testing Core provides core facilities and services to test mice in state of the art assays of simple and complex behaviors, including the assessment of circadian rhythms and sleep, learning and memory, motor and sensory function, as well as behavioral assays relevant to translational studies of neurological, neurodevelopmental and psychiatric disorders. The core offers comprehensive behavior phenotyping of your mice or can train your lab personnel to perform the tests in the facility. In addition, we provide consultation on study design including appropriate tests, mouse line/strain, numbers of animals, control groups and breeding strategies. The core will also provide consultation regarding ULAR, IACUC and other regulatory issues. Assistance with data analysis is also available. The behavior apparatus available in the core includes: running wheels and beam splitters to measure circadian activity and rest/activity patterns as well as EEG/EMG recording chambers to measure sleep/wake states. Motor function is assessed using open field activity monitors and Rotarod. Apparatus to measure anxiety-like behavior including zero maze, light/dark chamber, passive/active avoidance chambers and hole poke arenas are also available. Extensive assessment of cognition, learning and memory is conducted with Morris water maze, radial arm maze, 5 choice serial reaction time test and object recognition tests. Tests of behaviors associated with depression (forced swim), schizophrenia (startle/PPI), social interaction (choice and social memory), and drug addiction (conditioned place preference) are also available. Tests of general health and responsiveness are also performed, as these are critical for the evaluation of complex behavior. Support for the core is provided by the Comprehensive Neuroscience Center, the Institute for Translational Medicine and Therapeutics, the Center for Sleep and Circadian Neurobiology and the Perelman School of Medicine.

Proper citation: Penn Neurobehavior Testing Core (RRID:SCR_010024) Copy   

•   Source: SciCrunch Registry

http://hawaii.eagle-i.net/i/0000012d-4d11-7063-27fd-1f1480000000

The Harold L. Lyon Arboretum is a leader in the fields of conservation biology, Hawaiian ethnobotany and horticulture. On its 194 acres, Lyon Arboretum maintains a world renowned collection of more than 5,000 tropical plant species; supports Hawaii''s horticultural and agriculture industries; and works to preserve and restore Hawaii''s tropical forests. It is an active research facility and academic resource offering a wide range of programs to local and international communities including an innovative and ground-breaking tissue culture program for propagation of endangered native Hawaiian plants. With an abundant average rainfall of 165 inches, this tropical rainforest setting is an ideal location for growing an enormous diversity of plants. The plant collection features heliconias, gingers, aroids, bromeliads, native Hawaiian plants, and one of the largest palm collections found in a botanical garden.

Proper citation: UH Manoa Lyon Arboretum (RRID:SCR_010102) Copy   

•   Source: SciCrunch Registry

http://hawaii.eagle-i.net/i/0000012b-7f26-419c-2f73-b43980000000

Core facility that provides the following services: Tissue embedding service, Tissue sectioning service, Immunohistochemistry service, In situ hybridization service, DNA extraction service, Tissue microarray slides service, Tissue microarrays service, Genotyping service. The Pathology Shared resource capitalizes on the existing infrastructure of the Center''s tissue repository. The Repository currently consists of fixed, paraffin-embedded tissue specimens from hospitals and laboratories statewide. The purpose of the repository is to provide tissue specimens to Center members and other investigators for research purposes. A priority is placed on the provision of specimens for population-based research and peer-reviewed, extramurally funded projects. The repository is a part of the Residual Tissue Repository Program of the NCI SEER program (http://seer.cancer.gov/biospecimen/).

Proper citation: UH Manoa Pathology Shared Resources (RRID:SCR_010106) Copy   

•   Source: SciCrunch Registry

http://hawaii.eagle-i.net/i/0000012a-2510-e7b9-c99c-aef680000000

The Biostatistics and Data Management Facility (BDMF) was established with a primary mission to provide a range of customized statistical and database management services for RCMI researchers. Realizing a need for a consolidated and integrated statistical resources for biomedical researchers and clinicians at the John A. Burns School of Medicine, the BDMF has rapidly extended services to other programs and groups, including the Asia-Pacific Institute of Tropical Medicine and Infectious Diseases (APITMID), Pacific Biosciences Research Center (PBRC), Excellence in Partnerships for Community Outreach, Research on Health Disparities, and Training (EXPORT), Specialized Neuroscience Research Program (SNRP-I/II), Center of Biomedical Research Excellence (COBRE), Centers of Clinical Research Excellence (CCRE), Clinical Research Education and Career Development (CRECD), RCMI clinical Research Infrastructure Initiative (RCRII), and IDeA Networks of Biomedical Research Excellence (INBRE). The overall mission of the BDMF is to provide quantitative resources essential for investigators to conduct methodologically rigorous medical research in a timely, cost-effective manner. (http://www5.pbrc.hawaii.edu/bdmf/index.html)

Proper citation: UH Manoa RCMI Biostatistics and Data Management Facility (RRID:SCR_010107) Copy   

•   Source: SciCrunch Registry

http://hawaii.eagle-i.net/i/0000012a-2512-5807-c99c-aef680000000

Core facility provides the following services: DNA sequencing service, DNA fragment sizing and genotyping service, Real-time PCR analysis, DNA microarray analysis service, Protein sequencing service. The Greenwood Molecular Biology Facility is a primary research infrastructure operated by the Biotechnology Program of the Pacific Biosciences Research Center. Core serves the biomedical and molecular biology research and educational programs of the University and its associated institutions.

Proper citation: University of Hawaii at Manoa Greenwood Molecular Biology Facility (RRID:SCR_010108) Copy   

•   Source: SciCrunch Registry

http://hawaii.eagle-i.net/i/0000012b-1c5f-99ef-06c2-9c7f80000000

Core facility that provides the following services: Training and advice for general imaging techniques, Histology processing service, Hematoxylin and eosin staining service, Training and advice for general histology techniques. This lab provides routine histology processing, specialized histochemical and immunohistological techniques, and access to several microscopic platforms. The core also provides technical assistance, training, and consultation in histological and imaging techniques to investigators throughout the University on a cost-recovery basis.

Proper citation: UH Manoa RCMI Histology and Imaging Core Facility (RRID:SCR_010109) Copy   

•   Source: SciCrunch Registry

http://uccaribe.eagle-i.net/i/00000136-c5d0-1c3d-a53f-a15a80000000

Core facility that provides the following services: Protein separation service, 2D gel production, Analysis of protein distribution of 2D gel, Standardized imaging of 2D gel, Mass spectrometry analysis service, Desalting, Trypsin Digestion. The mission of the UCC Biomedical Proteomic Facility is to accelerate discovery by giving UCC investigators access to cutting edge mass spectrometry are rapidly advancing and requires considerable technical expertise and expensive equipments. To keep UCC scientists competitive, new technologies will be incorporated into the facility as soon as possible to meet the needs. The facility is open to all investigators on collaboration or a fee-for-service basis. User fees will be adjusted depending on demand and to keep costs competitive.

Proper citation: UCC Biomedical Proteomic Facility (RRID:SCR_010073) Copy   

•   Source: SciCrunch Registry

http://uccaribe.eagle-i.net/i/00000135-aaee-9c0e-a272-8ee780000000

Core facility that provides the following services: HIV and HCV viral load extraction, Amplification and detection of HCV and HIV viral load, HIV-1 and HCV drug resistance genotyping, Neurotoxicity and neuroprotection assays, PBMC antiviral assay, MAGI antiviral assay, HIV-1 Tat inhibition assay, HIV p24 measurement service, Cytokine/Chemokine measurement, Hormone measurement, NF-kB expression induction assay, Detection of TH1, TH2, Treg, and TH17 cytokine profiles in T lymphocytes subsets, Immunophenotyping, intracellular cytokines/chemokines and apoptosis assay service, B and T cell immune activation, function, proliferation and differentiation assays, Macrophage function assay, Cell viability, cell proliferation and cytotoxicity, Cell cycle analysis, Inflammation and oxidative stress Calcium mobilization, kinase activation, and signal transduction, Gene expression service, Apoptosis test, In vivo/in vitro cytotoxicity measurement, Plaque and colony formation counting, Inflammation antibody array service, Apoptosis antibody array service, Angiogenesis antibody array, Protein and gene expression study, Standardized imaging of 2D gel. The laboratory supports research in the areas of HIV/AIDS and substances of abuse. Specialized facilities are made available to researchers for scientific studies in fields of immunology, drugs of abuse, HIV/AIDS and related infectious diseases. The core lab provides researchers with assays for nucleic acids detection, virus genotyping, flow cytometric phenotyping, lymphocyte proliferation, cytotoxic and non-cytotoxic activity, cytokine and chemokine determinations, and drugs of abuse quantification.

Proper citation: UCC HIV and Substance of Abuse Laboratory Core (RRID:SCR_010076) Copy   

•   Source: SciCrunch Registry

http://uccaribe.eagle-i.net/i/00000136-cb34-a797-a53f-a15a80000000

Core facility that provides the following services: Immunocytochemistry service. The immunocytochemistry laboratory specializes in the qualitative identification and localization of cells bearing selective markers by employing specific antibodies to these molecules.

Proper citation: UCC Immunocytochemistry Laboratory (RRID:SCR_010077) Copy   

•   Source: SciCrunch Registry

http://uccaribe.eagle-i.net/i/00000136-ca9b-b63c-a53f-a15a80000000

Core facility that provides the following services: Qualitative measure of neuronal death, Computerized image analysis. The goal of the facility is to assist UCC investigators in the use of cultured neurons, glias and organotypic cultures. The cultures are used for patch clamping after in vitro treatments with drugs of addiction or inhibitors and for in vitro models of neurodegenerative diseases. The core facility consists of a coordinator and a technician. Neuronal cultures are prepared from fetal cortex, hippocampus or astrocytes from cerebral cortex.

Proper citation: UCC Neuronal Glia Culture Facility (RRID:SCR_010078) Copy   

•   Source: SciCrunch Registry

http://upr.eagle-i.net/i/0000012c-2c98-3564-5b95-f21080000000

Core facility that provides the following services: Necropsy and tissue collection, Blood chemistries service, Bronchoalveolar lavage service, Cerebro-spinal tap service. The Animal Resources Center (ARC) is a part of the Unit of Comparative Medicine at the Medical Sciences Campus (MSC) of the University of Puerto Rico (UPR), committed to offer quality services to the university community and private entities, which through an accredited and properly regulated facility, and highly qualified personnel, provides care and maintenance of animals to be used in research.

Proper citation: UPR Animal Resources Center (RRID:SCR_010111) Copy   

•   Source: SciCrunch Registry

http://uccaribe.eagle-i.net/i/00000136-d046-71cb-a53f-a15a80000000

THIS RESOURCE IS NO LONGER IN SERVICE. Documented on January 26,2026. The facility offers microscope-based systems that allow the assessment of cellular responses, such as calcium signaling with fast temporal resolution. The facility offers 1) Confocal imaging services; 2) Brightfield, darkfield, phase contrast, Nomarski and epi-fluorescence imaging; 3) High spatial and temporal resolution imaging, 4) Collection of serial sections (Deconvolution capabilities) and 5) Morphometric analysis.

Proper citation: UCC Optical Imaging Facility (RRID:SCR_010079) Copy   

•   Source: SciCrunch Registry

http://hawaii.eagle-i.net/i/0000012b-3599-5885-2f73-b43980000000

Core facility that provides the following services: Construction and validation of random-sheared DNA fragment libraries, DNA sequencing (Sanger) service, 96-well plasmid preparation service, Genotyping/fragment analysis, BAC end sequencing, Plasmid library construction service, Genome sequencing project. The ASGPB genome infrastructure currently consists of several state-of-the-art capillary-based DNA sequencers and accessory equipment to deal with large sample volumes. The facility can process up to 9000 samples per day with a projected sequence output of 6.75 Million bases. Several prokaryotic and one eukaryotic genome project are currently in progress. The facility offers DNA sequencing services for a wide range of templates including plasmid DNA, PCR fragments, cosmid DNA, and Bacterial Artificial Chromosomes (BACs). Sequencing reactions are performed using Applied Biosystems BigDye terminator chemistry and are run on ABI 3730XL capillary-based DNA sequencers.

Proper citation: UH Manoa Sequencing Facility (RRID:SCR_010114) Copy   

•   Source: SciCrunch Registry

http://upr.eagle-i.net/i/0000012b-00bf-6765-9e37-5ded80000000

Core facility that provides the following services: Sequencing service, Genotyping service. We are a low cost, fee-for-service facility designed to provide students and researchers in Puerto Rico with access to state-of-the-art equipment for collecting sequence and genotype data. We offer full service sequencing (reaction set-up, clean up, run and delivery) and fragment analysis data generation and offer personalized support to our users.

Proper citation: UPR AABRE Program: Sequencing and Genotyping Facility (RRID:SCR_010118) Copy   

•   Source: SciCrunch Registry

http://upr.eagle-i.net/i/0000012a-f732-79cc-6bbe-6fcf80000000

THIS RESOURCE IS NO LONGER IN SERVCE, documented January 24, 2019. Core aims to enhance biomedical research in Puerto Rico by providing resources for research, education and training. These resources will work to advance these specific aims: 1. enhance biomedical research in PR by providing researchers with the bioinformatics tools and technical support they require to perform cutting-edge biomedical research; 2. enhance the computational biology research environment in Puerto Rico by establishing research collaborations with biomedical, computational and mathematics researchers; 3. enhance multidisciplinary research by developing new courses and educational materials in computational biology, statistics and bioinformatics in collaboration with research faculty and the Science and Technology Competency Enhancement (STCE) Core; 4. enhance research by promoting advanced networking between PRAABRE member institutions, to enable collaborative research on and off the island; 5. enhance biomedical research by promoting effective access to scientific literature and databases for the biomedical researchers in PRAABRE; and 6. enhance biomedical research by enabling effective management of bibliographic information by fostering the use of bibliographic software and applying it to literature searches, articles and references management and manuscript writing.

Proper citation: University of Puerto Rico Biomedical Informatics Research Core (RRID:SCR_010119) Copy   

•   Source: SciCrunch Registry

http://hawaii.eagle-i.net/i/0000012f-0445-ea9e-1247-b2dc80000000

Core facility that provides the following services: MRI image analysis service, MRI image processing service.

Proper citation: UH Manoa Hawaii Center for AIDS Imaging Analysis Core (RRID:SCR_010083) Copy   

•   Source: SciCrunch Registry

http://hawaii.eagle-i.net/i/0000012a-2510-69a9-c99c-aef680000000

A 2000 square foot BSL-3 facility located at the University of Hawaii, JABSOM.

Proper citation: UH Manoa BSL-3 Containment Facility (RRID:SCR_010086) Copy   

•   Source: SciCrunch Registry

http://hawaii.eagle-i.net/i/0000012b-1c5f-469c-06c2-9c7f80000000

Core facility that provides the following services: Scanning electron microscopy service, Conventional and energy-filtering transmission electron microscopy service, Laser scanning confocal microscopy service, Fluorescence microscopy service, Laser microdissection and laser tweezing service. The Biological Electron Microscope Facility (BEMF) at the University of Hawai''i is a multi-user/service facility, administered by the Pacific Biosciences Research Center (PBRC). The mission of the BEMF is to provide biological-biomedical researchers with state-of-the-art instrumentation, training and services for high-resolution scanning electron microscopy, conventional and energy-filtering transmission electron microscopy, optical, fluorescence, and laser scanning confocal microscopy, and image analysis on a recharge basis. The facility receives partial support from the Pacific Biosciences Research Center and the UH Manoa Chancellor''s Office. Includes the Richard Allen Image Collection, a unique set of images taken with electron microscopes (http://www5.pbrc.hawaii.edu/allen/).

Proper citation: UH Manoa Biological Electron Microscope Facility (RRID:SCR_010087) Copy   

•   Source: SciCrunch Registry

http://upr.eagle-i.net/i/0000012d-1479-c6f4-bc92-16e380000000

Cayo Santiago is one of the world''s most renowned field sites for short term and longitudinal non-human primate studies. Its unique research value consists of:a stable and minimally disrupted long-term population management policy which allows investigators to plan and conduct longitudinal studies, an extensive and detailed computerized demographic database on the colony that provides information on individuals dating back to 1957, and DNA fingerprinting which is applied to confirm maternal and paternal relatedness of individuals.

Proper citation: UPR Cayo Santiago Caribbean Primate Research Center (RRID:SCR_010120) Copy   

•   Source: SciCrunch Registry