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SciCrunch Registry is a curated repository of scientific resources, with a focus on biomedical resources, including tools, databases, and core facilities - visit SciCrunch to register your resource.
http://www.scienceexchange.com/facilities/australian-microscopy-microanalysis-research-facility
The Australian Microscopy & Microanalysis Research Facility (AMMRF) is Australia''s leading facility for the characterisation of matter on a fine scale. We specialise in instrumentation, methodologies and applications for characterising samples in the physical, biological and environmental sciences using ion and electron beams, scanned probes, X-rays as well as light and laser optics. The six AMMRF nodes are located at the host universities in Adelaide, Brisbane, Canberra, Perth and Sydney. More information is available at www.ammrf.org.au and at http://www.ammrf.org.au/techniquefinder.
Proper citation: Australian Microscopy and Microanalysis Research Facility (RRID:SCR_011035) Copy
https://mann.usc.edu/core-facilities/lentiviral-lab/
USC School of Pharmacy Lentiviral Laboratory, located on the second floor of the Pharmaceutical Sciences Center, provides services for production of small-scale lentiviral stocks containing the gene of interest, lentiviral titrations, concentrations and transductions of cells of interest. We also construct individual lentiviral vectors including sub-cloning of the gene of interest into a pLVX-puro lentiviral vector.
Proper citation: University of Southern California School of Pharmacy Lentiviral Laboratory Core Facility (RRID:SCR_011036) Copy
The Angiogenesis, Endothelial & Pro-Angiogenic Cell Core (AEPCC) is a state-of-the-art facility that has been established through the Indiana University Melvin and Bren Simon Cancer Center, a National Cancer Institute-designated cancer center, to conduct validated and highly reproducible in vitro and in vivo angiogenesis, endothelial, hematopoietic and multi-parametric flow cytometry assays and their role in normal and patient-related hematologic and cardiovascular disorders. In addition to possessing the in vitro and in vivo assays that define the endothelial progenitor outgrowth cells that possess in vivo vessel forming ability, the AEPCC recently stringently defined a population of pro-angiogenic and anti-angiogenic circulating hematopoietic stem and progenitor cells (CHSPCs) that has been shown to regulate angiogenesis. Discovery of these novel CHSPC subsets demonstrates the uniqueness and strength of the approach by the AEPCC that requires both phenotypic and functional data to validate specific circulating cells that participate in new blood vessel formation. The specific assays offered by the AEPCC function as quantitative analytical tools, potential biomarkers of several hematopoietic diseases, and as experimental platforms for understanding the basic mechanisms of angiogenesis and the interplay between the endothelial and hematopoietic systems. For example, not only are CHSPCs critical for normal and abnormal angiogenesis, but we and others have reported that certain endothelial cells are critical for CHSPC expansion ex vivo and that endothelial cells promote CHSPC engraftment post-ablation. The AEPCC serves to directly perform all of the assays required to analyze research samples, and as a consultation, education, and new assay development site for scientists within and outside the IU School of Medicine and Indiana University. Furthermore, the AEPCC is one of only five nationally recognized Core Centers of Excellence in Molecular Hematology by the National Institutes of Health and is a certified core of the Indiana Clinical and Translational Sciences Institute (CTSI).
Proper citation: IUSM Angiogenesis Endothelial and Pro-Angiogenic Cell Core (RRID:SCR_011001) Copy
http://www.scienceexchange.com/facilities/genomics-core-facility-lsu
The Genomics Core Facility seeks to achieve high quality research data production through education of core facility users, optimal use of qPCR and RNA/DNA quality and quantity instrumentation, and quality Sanger sequencing, next-generation sequencing, robotics, and microarray services. Services are provided to internal and external researchers.
Proper citation: LSU Genomics Core Facility (RRID:SCR_011004) Copy
http://www.scienceexchange.com/facilities/magnetic-resonance-research-facility-mrrf-uiowa
The University of Iowa MR Research Facility was established in August of 2004 with the acquisition of a Siemens Trio 3T scanner, shared between research and clinical usage. While the Center is within the Department of Radiology, it is run as a Core University facility. The facility is managed on a daily basis by Vincent Magnotta, PhD, Alan Stolpen, MD, PhD, and Dan Thedens, PhD. Oversight is provided by a Research Advisory committee that reviews new project proposals and equipment acquisitions. Since its inception, the equipment managed by the Research Center has expanded. In 2006, a research dedicated Siemens Avanto 1.5T scanner was loaned to the University by Siemens Medical Solutions to support research studies. Then, in 2007 an NIH/NCRR High End Instrumentation grant supported the acquisition of a research dedicated Siemens TIM Trio 3T scanner. Standard operating hours for the research-dedicated 3T TIM Trio scanner are from 8:00 a.m. to 6:00 p.m., Monday through Friday. During this time, a technologist is provided to run the scanner. The shared research 3T TIM Trio scanner is available all day Tuesdays (8:00 a.m. - 4:30 p.m.), and Thursday afternoons (12:00 p.m. - 4:30 p.m.) for research studies. The shared Avanto 1.5T scanner is available Mondays, Wednesdays and Fridays from 2:00 p.m. to 4:00 p.m. The scanners are also available after-hours if technologist coverage is available, or if the user is certified to conduct MR studies on their own. The current rate for scanner usage is $600 per hour and can be scheduled in half hour increments.
Proper citation: University of Iowa Magnetic Resonance Research Facility (RRID:SCR_011014) Copy
http://www.scienceexchange.com/facilities/next-generation-sequencing-ngs-core
THIS RESOURCE IS NO LONGER IN SERVICE. Documented on May 15,2024. Laboratory: The Institute for Genomics and Systems Biology''''s Next Generation Sequencing Core (IGSB-NGS) is a state-of-the-art facility for ultra-high throughput sequencing. The core was established in 2007 at Argonne National Laboratory and is housed in Argonne''''s Computing, Environment and Life Sciences (CELS) directorate, providing world class computation power, software, and expertise critical to the acquisition, analysis, and interpretation of the unprecedented volume of genetic information being generated on next generation DNA sequencing platforms. The core provides resources and services to Argonne National Laboratory users, University of Chicago users, and to the broader scientific community. NGS is involved in a broad range of scientific research from the sequencing of metagenomic samples to both 16S and 18S rRNA amplicon sequencing for microbial community analysis using next generation sequencing. The NGS laboratory space at Argonne is approximately 1,200 square feet and is supplemented by 140 square feet of office space for the technical director, Ms. Sarah Owens, as well as two additional 140 square foot spaces for technicians. Equipment: The NGS maintains the following workflows: Illumina HiSeq2000 and MiSeq next generation DNA sequencing. The Illumina HiSeq2000 generates over 6 billion reads at 150 bp in length per read resulting in over 600 Gb worth of data across sixteen lanes available per run. The Illumina MiSeq generates over 24 million reads at 150 bp in length per read resulting in over 4.5 Gb worth of data available per run (over a single lane). Applications on both the Illumina HiSeq2000 and MiSeq include: shotgun metagenome sequencing; rRNA-based amplicon library sequencing; and genome sequencing and resequencing. All major equipment is housed within the main laboratory space including three 96-well PCR machines (Applied Biosystems), water baths, analytical balances, refrigerator/freezers (including a large-capacity -80 degree C freezer), incubators, and high and low speed centrifuges (table-top and floor models). Basic equipment and supplies for all advanced molecular techniques (deionized water (Millipore Milli-Q Advantage A10 system), multiple electrophoresis units and digital photographic documentation system) are housed here including equipment for high precision quantitation of nucleic acids (Agilent Bioanalyzer, NanoDrop, and Invitrogen Qubit). The facility also has a Covaris for sample shearing. Any additional equipment needed is located in or near by the NGS laboratory space including a real-time PCR machine (Roche LightCycler 480 with capabilities for both 96-well and 384-well plates) and a liquid handler, the Eppendorf epMotion 5075 robot. Some equipment (autoclaves, ice machine) is located in a common equipment room. Various instruments and methods have been implemented in the NGS''''s standard procedures to maximize quality. These include the use of the Roche Lightcycler 480 II, Agilent Bioanalyzer 2100, Invitrogen Qubit Fluorometer, and barcoding of libraries destined for sequencing. (The latter allows for a test sequencing run of each library to be performed to optimize sequencing lane loading density prior to each library''''s final sequencing run). Personnel overview. NGS operations are managed by Technical Director Sarah Owens. Ms. Owens has a Masters in Molecular Biology and Genetics, and 2 years experience working in high throughput facilities, with over 6 years of molecular biology experience. Ms. Owens was instrumental in trouble-shooting the application of rRNA-based amplicon sequencing for the Illumina HiSeq2000 and MiSeq, developing reproducible protocols in collaboration with Illumina. Under the guidance of the Technical Director, the NGS team helps users to determine the most efficient and cost effective approach to meet their research needs.
Proper citation: UChicago IGSB Next Generation Sequencing Core (RRID:SCR_011063) Copy
http://www.scienceexchange.com/facilities/photonics-research-centre
THIS RESOURCE IS NO LONGER IN SERVICE. Documented on May 2,2024. We undertake fundamental and applied research in the general area of lasers and photonics, with particular focus on the following seven frontiers of optical science: astrophotonics; biophotonics; microphotonic optical systems; nano-optics and nanophotonics; photonic sources; optical sensing and imaging; ultrafast laser applications.
Proper citation: Macquarie University Photonics Research Centre (RRID:SCR_011068) Copy
http://www.med.upenn.edu/genetics/dnaseq/index.shtml
Core facility that provides the following services: Large sequencing project support, Sanger sequencing service, High throughput DNA sequencing, Ion Torrent Personal Genome Machine sequencing, Template preparation and purification, Roche 454 sequencing, Sequence analysis and database search support, Construction of targeting vector for gene targeting, Genotyping and Fragment Analysis service, Molecular biology services, Mouse genotyping, and Ion Personal Genome Machine sequencing data analysis. The DNA Sequencing Facility provides long read, automated Sanger sequencing; microsatellite-based genotyping and fragment analysis; plasmid and BAC DNA preparation and purification; and related molecular biological services including PCR, cloning, sub-cloning, site-directed mutagenesis, and preparation of targeting vectors for gene targeting in mice. Core also provides services and support for analysis and interpretation of sequence data as well as the design of approaches to complex sequencing projects. For the last four years the facility has been providing Roche 454 sequencing service that includes library preparation, emulsion PCR and pyrosequencing for both genomic DNA and amplicons.
Proper citation: University of Pennsylvania Genomics Analysis Core (RRID:SCR_011061) Copy
The ARC Centre of Excellence for Engineered Quantum Systems seeks to engineer complex, multi-component, quantum systems for new science and new applications. Cross-disciplinary scientific advances will link quantum physics with engineering, chemistry, and biology; and sophisticated technologies will be developed for 21st Century Australian industries. The EQuS collaboration possesses experimental capabilities in all major successful quantum technologies including spins in semiconductors, superconducting circuits, opto- and nano-mechanics, trapped atoms, and quantum photonics.
Proper citation: MQ ARC Centre of Excellence for Engineered Quantum Systems (RRID:SCR_011073) Copy
http://www.scienceexchange.com/facilities/fauna-park
Situated on the corner of Culloden Rd and Tallavera Rd, Marsfield and originally farmed as market gardens, the Macquarie University Fauna Park stretches over 11Ha; 3.5Ha of which is protected Sydney Turpentine Ironbark Forest. The area is committed to non-intrusive research, e.g. learning to avoid predation, and other natural animal behaviours. Vertebrates (birds, fish, reptiles) or invertebrates (bees, flies, spiders) are observed in natural settings with minimal disruption to their normal environment. This allows the researchers to verify findings they have documented in the field. Other areas of investigation are water ecology and the competitive abilities of native trees.
Proper citation: Macquarie University Fauna Park (RRID:SCR_011075) Copy
http://www.scienceexchange.com/facilities/wireless-communications-and-networking-laboratory-wcnl
THIS RESOURCE IS NO LONGER IN SERVICE. Documented on April 15,2024. The Wireless Communications and Networking Laboratory (WCNL) at Macquarie University conducts research into emerging wireless communications and networking technologies.
Proper citation: Macquarie University Wireless Communications and Networking Laboratory (RRID:SCR_011076) Copy
http://www.scienceexchange.com/facilities/guided-wave-optics-and-photonics-research-group-gwopr
The Guided Wave Optics and Photonics Research group (GWOPR) undertakes teaching, research, and development in the area of guided-wave optics, including integrated optics and optical fibres, specialising in microstructured and nanostructured materials. The group''s research capabilities are broad, but mainly target applications in telecommunications and sensing.
Proper citation: Macquarie University Guided Wave Optics and Photonics Research group (RRID:SCR_011077) Copy
http://www.scienceexchange.com/facilities/the-ramaciotti-centre-for-gene-function-analysis
THIS RESOURCE IS NO LONGER IN SERVICE. Documented on April 22, 2024. Ramaciotti Centre for Gene Function Analysis was established in August 2000 as a focus for the development and application of Functional Genomics in New South Wales. The Centre is consortium of five universities and five medical research centres in the Sydney-Newcastle region.
Proper citation: MQ Ramaciotti Centre for Gene Function Analysis (RRID:SCR_011071) Copy
http://www.scienceexchange.com/facilities/rodent-behavior-core-nyu
THIS RESOURCE IS NO LONGER IN SERVICE. Documented on April 24,2024. Rodent Behavior Core, located in Berg, is slated to open to the NYULMC research community in September, 2012. The Rodent Behavior Core will provide facilities and equipment for: -Spatial Learning and Memory (Morris Water Maze, Place Preference) -Associative Memory Formation (Fear Conditioning) -Anxiety and Depression (Elevated Plus, Forced Swim, Tail Suspension, Sucrose Preference) -Sensory Motor Gating (Prepulse Inhibition, Acoustic Startle) -Drug Addiction and Withdrawal (Conditioned Place Preference, Locomotor Hyperactivity) -Social Learning (Three Chambered Arena) -Novelty Detection (Objection Recognition) -Motor Learning (Rotating Rod test) -Perseverative Learning (Y-Maze) -Working Memory (Radial Arm Maze) -Real time video tracking to adapt user designed paradigms
Proper citation: NYU Rodent Behavior Core (RRID:SCR_010983) Copy
http://www.scienceexchange.com/facilities/australian-synchrotron
The Australian Synchrotron is a source of highly intense light ranging from infrared to hard x-rays used for a wide variety of research purposes. Officially opened in July 2007, the Australian Synchrotron is one of fewer than 40 similar facilities around the world. It is the largest stand-alone piece of scientific infrastructure in the southern hemisphere.
Proper citation: Australian Synchrotron (RRID:SCR_010984) Copy
http://www.scienceexchange.com/facilities/stem-cell-research-center
THIS RESOURCE IS NO LONGER IN SERVICE. Documented on April 23,2024. Institutional Stem Cell Core has been discontinued, with the functions of the former Core now split into two separate operations. iPSCs: The generation and characterization of induced Pluripotent Stem Cells (iPSCs) is now being performed on a collaborative basis for both internal and external investigators. Shared Laboratory: A well-equipped shared laboratory dedicated to the culture and analysis of stem cells is available to SBP investigators.
Proper citation: Sanford-Burnham Stem Cell Core Facility (RRID:SCR_011039) Copy
http://www.scienceexchange.com/facilities/australian-proteome-analysis-facility
APAF Ltd - Australian Proteome Analysis Facility, was the birthplace of the term proteomics in 1995 and was the world''''s first dedicated high throughput proteomics laboratory. APAF has over 15 years of experience in providing proteomic services, and combined with our leading edge infrastructure and expertise we provide total solutions for all your proteomic research needs. APAF''''s mission is to assist the scientific community address their protein analysis needs.
Proper citation: MQ Australian Proteome Analysis Facility (RRID:SCR_011040) Copy
http://www.scienceexchange.com/facilities/mass-spectrometry-core
The Mass Spectrometry Core is dedicated to providing a wide range of mass spectral analyses. As an integral component of the BRF Proteomics Section, it is a vital proteomics resource, providing high quality data in a timely manner and engaging investigators in the interpretation of the results.
Proper citation: UTMB Mass Spectrometry Core (RRID:SCR_011041) Copy
http://www.waksman.rutgers.edu/genomics/home
Equipped with NextSeq500, MiSeq, and Ion Proton performs de novo genome sequencing, genome resequencing, ChIP-Seq and RNA-seq. Performs library construction, template preparation and sequencing of libraries or provides training in library preparation methods.Performs procedures to enrich or remove polyadenylated RNA, rRNA and/or tRNA as needed. Provides bioinformatics support for projects,data management and analysis plan before selecting samples and initiating data collection.
Proper citation: Rutgers University Waksman Institute of Microbiology Genomics Core Facility (RRID:SCR_011042) Copy
http://www.scienceexchange.com/facilities/deep-sequencing-and-microarray-core
Our aim is to provide cost-effective and time-efficient access to cutting-edge genomic technologies and expert assistance with experimental design and data analysis.
Proper citation: JHU Deep Sequencing and Microarray Core (RRID:SCR_011045) Copy
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