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SciCrunch Registry is a curated repository of scientific resources, with a focus on biomedical resources, including tools, databases, and core facilities - visit SciCrunch to register your resource.

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Resource Name Proper Citation Abbreviations Resource Type Description Keywords Resource Relationships Related Condition Funding Defining Citation Availability Website Status Alternate IDs Alternate URLs Old URLs Parent Organization Resource ID Synonyms Record Last Update Mentions Count
Influenza Ontology
 
Resource Report
Resource Website
Influenza Ontology (RRID:SCR_003346) FLU data or information resource, ontology, controlled vocabulary An application ontology established by a collaborative group of influenza researchers that includes consolidated influenza sequence and surveillance terms from resources such as the BioHealthBase (BHB), a Bioinformatics Resource Center (BRC) for Biodefense and Emerging and Re-emerging Infectious Diseases, the Centers for Excellence in Influenza Research and Surveillance (CEIRS) owl, health, pathological, organismal, cellular, sequence, surveillance is listed by: BioPortal
is listed by: OBO
is related to: Information Artifact Ontology
has parent organization: University of Maryland; Maryland; USA
Influenza Free, Freely available nlx_157440 http://purl.obolibrary.org/obo/flu.owl
http://influenzaontologywiki.igs.umaryland.edu/
http://purl.bioontology.org/ontology/FLU SCR_003346 2026-02-17 09:59:59 0
COnsensus-DEgenerate Hybride Oligonucleotide Primers
 
Resource Report
Resource Website
1+ mentions
COnsensus-DEgenerate Hybride Oligonucleotide Primers (RRID:SCR_002875) software application, production service resource, data processing software, data analysis software, analysis service resource, service resource, software resource, data analysis service This COnsensus-DEgenerate Hybrid Oligonucleotide Primer (CODEHOP) strategy has been implemented as a computer program that is accessible over the World-Wide Web and is directly linked from the BlockMaker multiple sequence alignment site for hybrid primer prediction beginning with a set of related protein sequences. This is a new primer design strategy for PCR amplification of unknown targets that are related to multiply-aligned protein sequences. Each primer consists of a short 3' degenerate core region and a longer 5' consensus clamp region. Only 3-4 highly conserved amino acid residues are necessary for design of the core, which is stabilized by the clamp during annealing to template molecules. During later rounds of amplification, the non-degenerate clamp permits stable annealing to product molecules. The researchers demonstrate the practical utility of this hybrid primer method by detection of diverse reverse transcriptase-like genes in a human genome, and by detection of C5 DNA methyltransferase homologs in various plant DNAs. In each case, amplified products were sufficiently pure to be cloned without gel fractionation. Sponsors: This work was supported in part by a grant from the M. J. Murdock Charitable Trust and by a grant from NIH. S. P. is a Howard Hughes Medical Institute Fellow of the Life Sciences Research Foundation., THIS RESOURCE IS NO LONGER IN SERVICE. Documented on January 15,2026. fractionation, gel, 3', amplification, clone, dna, genome, homolog, human, hybrid, molecule, oligonucleotide, pcr, plant, primer, protein, sequence, transcriptase-methyltransferase is related to: OMICtools
has parent organization: University of Washington; Seattle; USA
THIS RESOURCE IS NO LONGER IN SERVICE nif-0000-25557 SCR_002875 CODEHOP 2026-02-17 10:00:00 8
LAST
 
Resource Report
Resource Website
100+ mentions
LAST (RRID:SCR_006119) LAST software application, production service resource, data processing software, analysis service resource, service resource, software resource, data analysis service THIS RESOURCE IS NO LONGER IN SERVICE. Documented on February 28,2023. Software tool for aligning sequences, similar to BLAST 2 sequences that colour-codes the alignments by reliability. Another useful feature of LAST is that it can compare huge (vertebrate-genome-sized) datasets. Unfortunately, this only applies to the downloadable version of LAST, not the web service. The web service can just about handle bacterial genomes, but it will take a few minutes and the output will be large. LAST can: * Handle big sequence data, e.g: ** Compare two vertebrate genomes ** Align billions of DNA reads to a genome * Indicate the reliability of each aligned column. * Use sequence quality data properly. * Compare DNA to proteins, with frameshifts. * Compare PSSMs to sequences * Calculate the likelihood of chance similarities between random sequences. LAST cannot (yet): * Do spliced alignment., THIS RESOURCE IS NO LONGER IN SERVICE. Documented on September 16,2025. sequence alignment, align, vertebrate, genome, sequence, alignment, bio.tools is listed by: OMICtools
is listed by: bio.tools
is listed by: Debian
is related to: RecountDB
has parent organization: National Institute of Advanced Industrial Science and Technology
National Genome Research Network ;
INTEuropean Union Systems Institute ;
Japanese Ministry of Education Culture Sports Science and Technology MEXT
PMID:21209072
PMID:20144198
PMID:20110255
DOI:10.1093/nar/gkq010
THIS RESOURCE IS NO LONGER IN SERVICE nlx_151594, biotools:last, OMICS_15813 https://bio.tools/last
https://sources.debian.org/src/last-align/
SCR_006119 2026-02-17 10:00:45 397
FASTA
 
Resource Report
Resource Website
500+ mentions
FASTA (RRID:SCR_011819) FASTA software application, data processing software, data analysis software, software resource, sequence analysis software Software package for DNA and protein sequence alignment to find regions of local or global similarity between Protein or DNA sequences, either by searching Protein or DNA databases, or by identifying local duplications within a sequence. sequence, alignment, DNA, protein, similarity, searching is listed by: OMICtools
is listed by: SoftCite
has parent organization: European Bioinformatics Institute
Free, Freely available OMICS_00994 SCR_011819 Federal Acquisition STreamlining Act 2026-02-17 10:01:58 845
Vmatch
 
Resource Report
Resource Website
10+ mentions
Vmatch (RRID:SCR_018968) software application, data processing software, data analysis software, software resource, sequence analysis software Software tool for efficiently solving large scale sequence matching tasks. Sequence analysis, large scale, sequence matching, sequence, matching, bio.tools is listed by: bio.tools
is listed by: Debian
is listed by: OMICtools
is listed by: SoftCite
has parent organization: University of Hamburg; Hamburg; Germany
Free, Available for download, Freely available OMICS_19963, biotools:vmatch https://bio.tools/vmatch
https://sources.debian.org/src/vmatch/
SCR_018968 2026-02-17 10:03:53 35
StringTie
 
Resource Report
Resource Website
1000+ mentions
StringTie (RRID:SCR_016323) software application, data processing software, data analysis software, software resource, sequence analysis software Software application for assembling of RNA-Seq alignments into potential transcripts. It enables improved reconstruction of a transcriptome from RNA-seq reads. This transcript assembling and quantification program is implemented in C++ . assembling, RNA, sequence, transcript, gene, alignment, reconstruction, read, analysis, process, bio.tools is listed by: bio.tools
is listed by: Debian
is listed by: OMICtools
the Cancer Prevention and Research Institute of Texas ;
NHGRI R01 HG006677;
NIGMS R01 GM105705;
NHGRI R01 HG006102;
NCI R01 CA120185;
NCI R01 CA134292
PMID:25690850
DOI:10.1038/nbt.3122
Open source, Free, Freely available, Available for download biotools:stringtie, OMICS_07226 https://github.com/gpertea/stringtie
https://bio.tools/stringtie
https://sources.debian.org/src/stringtie/
SCR_016323 2026-02-17 10:03:23 4072
Hinge
 
Resource Report
Resource Website
1+ mentions
Hinge (RRID:SCR_016135) software application, data processing software, data analysis software, software resource, sequence analysis software Software application for long read genome assembly based on hinging. Used in long-read sequencing technologies in genome assemblies to achieve optimal repeat resolution. long, read, genome, assembly, hinging, sequence, optimal, repeat, resolution is listed by: Debian
is listed by: OMICtools
PMID:28320918 Free, Available for download OMICS_12339 https://sources.debian.org/src/hinge/ SCR_016135 2026-02-17 10:02:58 9
FreeContact
 
Resource Report
Resource Website
10+ mentions
FreeContact (RRID:SCR_016113) software application, data processing software, software resource, image analysis software, alignment software Alignment software for large-scale protein contact or protein-protein interaction prediction optimized for speed through shorter runtimes. FreeContact provides the opportunity to compute contact predictions in any environment (desktop or cloud). protein, structure, prediction, sequence, analysis, fast, contact, alignment, multiple is listed by: OMICtools
is related to: Debian
Alexander von Humboldt Foundation ;
German Ministry for Research and Education (BMBF: Bundesministerium fuer Bildung und Forschung) ;
Research Council of Norway 208481
PMID:24669753
DOI:10.1186/1471-2105-15-85
Open source, Free, Available for download OMICS_03520 https://rostlab.org/owiki/index.php/FreeContact
https://sources.debian.org/src/libfreecontact-perl/
SCR_016113 2026-02-17 10:03:18 21
ClonalOrigin
 
Resource Report
Resource Website
1+ mentions
ClonalOrigin (RRID:SCR_016061) software application, data processing software, data analysis software, software resource, sequence analysis software Software package for comparative analysis of the sequences of a sample of bacterial genomes in order to reconstruct the recombination events that have taken place in their ancestry. comparative, analysis, sequence, bacteria, genome, reconstruct, recombination, events, ancestry, bayesian is listed by: Debian
is listed by: OMICtools
is related to: Imperial College London; London; United Kingdom
is related to: Wellcome Trust Sanger Institute; Hinxton; United Kingdom
Wellcome Trust WT082930MA;
National Science Foundation DBI-0630765;
Science Foundation of Ireland 05/FE1/B882
PMID:20923983
DOI:10.1534/genetics.110.120121
Free, Available for download OMICS_18881 https://sources.debian.org/src/clonalorigin/ SCR_016061 2026-02-17 10:02:57 8
PseudoFuN
 
Resource Report
Resource Website
1+ mentions
PseudoFuN (RRID:SCR_017095) data or information resource, production service resource, analysis service resource, database, service resource, data analysis service Software as database and query tool for homologous pseudogene and coding gene families. Collection of human pseudogenes and gene associations. Supports search, graphical visualization and functional analysis of pseudogenes and coding genes based on PGG families. gene, pseudogene, sequence, homology, regulatory, network, miRNA, coexpression, noncoding, RNA, TCGA, cancer has parent organization: Ohio State University; Ohio; USA
has parent organization: Indiana University School of Medicine; Indiana; USA
NLM T15 LM011270 Free, Freely available https://github.com/yanzhanglab/PseudoFuN_app SCR_017095 Pseudogene Functional Networks 2026-02-17 10:02:48 2
SMARTdenovo
 
Resource Report
Resource Website
100+ mentions
SMARTdenovo (RRID:SCR_017622) software application, data processing software, software resource, image analysis software, alignment software Software tool as de novo assembler for PacBio and Oxford Nanopore data. It produces assembly from all-vs-all raw read alignments without error correction stage. Allows to read overlapping, rescue missing overlaps, identify low-quality regions and chimaera and produce better consensus. De novo, assembler, PacBio, Oxford Nanopore, data, sequence, raw, read, alignment, error, bio.tools is listed by: Debian
is listed by: bio.tools
Free, Available for download, Freely available BioTools:SMARTdenovo, biotools:SMARtdenovo https://bio.tools/SMARTdenovo
https://bio.tools/SMARTdenovo
https://bio.tools/SMARTdenovo
SCR_017622 2026-02-17 10:03:37 159
duphold
 
Resource Report
Resource Website
1+ mentions
duphold (RRID:SCR_016938) data analysis software, software application, data processing software, software resource Software tool to annotate structural variant calls with sequence depth information that can add or remove confidence to SV predicted to affect copy number. Indicates the presence of a rapid change in depth relative to the regions surrounding the breakpoints. Allows the run time to be nearly independent of the number of variants important for large, jointly called projects with many samples. Annotates structural variant predictions made from both short read and long read data. annotate, structural, variation, call, sequence, depth, confidence, predict, copy, number, short, long, read, data is listed by: OMICtools Free, Available for download, Freely available SCR_016938 2026-02-17 10:03:30 2
QModeling
 
Resource Report
Resource Website
1+ mentions
QModeling (RRID:SCR_016358) software application, data processing software, data analysis software, software resource, software toolkit, image analysis software Software toolbox for Statistical Parametric Mapping (SPM) to fit reference-region kinetic models (SRTM, SRTM2, Patlak Reference and Logan Reference Plot) are currently available in QModeling to dynamic PET studies. Used for the analysis of brain imaging data sequences. statistical, parametric, mapping, reference, region, kinetic, model, dynamic, analysis, brain, data, imaging, sequence is related to: University of Malaga; Andalusia; Spain
is related to: MATLAB
DOI:10.1007/s12021-018-9384-y Free, Available for download, Available after registration SCR_016358 2026-02-17 10:03:24 1
OGDraw
 
Resource Report
Resource Website
100+ mentions
OGDraw (RRID:SCR_017337) OGDRAW software application, data processing software, software resource, service resource, software toolkit, data visualization software Software package for graphical visualization of organellar genomes. Converts annotations in GenBank format into graphical maps. Used to create visual representations of circular and linear annotated genome sequences provided as GenBank files or accession numbers. graphical, visualization, organellar, genome, convert, annotation, GenBank, format, map, DNA, sequence works with: GenBank Max Planck Society PMID:30949694 Free, Freely available SCR_017337 Draw Organelle Genome Maps, OrganellarGenomeDRAW 2026-02-17 10:03:34 214
NanoPipe
 
Resource Report
Resource Website
1+ mentions
NanoPipe (RRID:SCR_016852) NanoPipe data access protocol, production service resource, analysis service resource, service resource, software resource, web service, data analysis service Web tool for analysis of MinION (ONT) long sequencing reads. Used for analysis of reads generated by the Oxford Nanopore sequencing devices. Provides alignments to any target of interest, alignment statistics and information about polymorphisms. analysis, MinION, long, sequence, read, Oxford Nanopore, alignment, target, statistics, polymorphism, bio.tools is listed by: Debian
is listed by: bio.tools
has parent organization: University of Muenster; Muenster; Germany
Institute of Bioinformatics Muenster ;
Germany
PMID:30689855 Free, Available for download, Freely Available biotools:NanoPipe https://github.com/IOB-Muenster/nanopipe2
https://bio.tools/NanoPipe
SCR_016852 NanoPipe, nanopipe2 2026-02-17 10:03:30 5
DETONATE
 
Resource Report
Resource Website
1+ mentions
DETONATE (RRID:SCR_017035) DETONATE software application, data processing software, data analysis software, software resource, sequence analysis software Software tool to evaluate de novo transcriptome assemblies from RNA-Seq data. Consists of RSEM-EVAL and REF-EVAL packages. RSEM-EVAL is reference-free evaluation method. REF-EVAL is reference based and can be used to compare sets of any kinds of genomic sequences. evaluate, de novo, transcriptome, assembly, RNAseq, data, RSEM-EVAL, REF-EVAL, dataset, genomic, sequence, bio.tools is listed by: bio.tools
is listed by: Debian
has parent organization: University of Wisconsin-Madison; Wisconsin; USA
NHGRI R01 HG005232;
NLM T15 LM007359
PMID:25608678 Free, Available for download, Freely available biotools:detonate https://bio.tools/detonate SCR_017035 DE novo TranscriptOme rNa-seq Assembly with or without the Truth Evaluation, DETONATE 2026-02-17 10:02:47 2
Washington University Basic Local Alignment Search Tool
 
Resource Report
Resource Website
1000+ mentions
Washington University Basic Local Alignment Search Tool (RRID:SCR_008285) software application, data processing software, software resource It is used to compare a novel sequence with those contained in nucleotide and protein databases by aligning the novel sequence with previously characterized genes. evolutionary, fragment, function, functional, gene, genetic code, algorithm, align, alignment, blast, local, novel, nucleotide, pair, protein, region, segment, sensitivity, sequence, similarity, structure, tool has parent organization: European Molecular Biology Laboratory nif-0000-23905 SCR_008285 WU-BLAST2 2026-02-17 10:01:12 3631
CESG
 
Resource Report
Resource Website
1+ mentions
CESG (RRID:SCR_008451) CESG data or information resource, portal, organization portal It is a specialized research center supported by the Protein Structure Initiative (PSI) of the National Institute of General Medical Sciences (NIGMS), one of the National Institutes of Health (NIH). PSI is a federal, university, and industry effort aimed at dramatically reducing the costs and lessening the time it takes to determine a three-dimensional protein structure. The long-range goal of PSI is to solve 10,000 protein structures in 10 years and to make the three-dimensional atomic-level structures of most proteins easily obtainable from knowledge of their corresponding DNA sequences. CESG is located within the Department of Biochemistry at the University of Wisconsin-Madison (Madison, WI) and the Department of Biochemistry at the Medical College of Wisconsin (Milwaukee, WI). CESG develops new methods and technologies to address unique eukaryotic bottlenecks and disseminates its methodologies and experimental results to the scientific community worldwide through: :- Cell-Free Protein Production Workshops :- Plasmids at PSI Materials Repository :- Posters Presented at Scientific Meetings :- Publications in PubMed / PubMed Central :- Sesame (LIMS) Available for Researchers :- Solved Structures in the Protein Data Bank :- Technology Dissemination Reports They have welcomed requests by researchers to solve eukaryotic protein structures, particularly medically relevant proteins, through our Online Structure Request System for Researchers. They have solved many community-nominated targets and deposited information about these targets in public databases and published on our investigations and findings. Sponsors: CESG is supported by NIH / NIGMS Protein Structure Initiative grant numbers U54 GM074901 and P50 GM064598. eukaryotic, structural, genomics, research, center, protein, structure, medical, science, health, atom, dna, sequence, knowledge, biochemistry, technology, cell, plasmid has parent organization: University of Wisconsin-Madison; Wisconsin; USA nif-0000-30322 SCR_008451 Center for Eukaryotic Structural Genomics, The Center for Eukaryotic Structural Genomics 2026-02-17 10:01:21 9
Center for Computational Biology at JHU
 
Resource Report
Resource Website
1+ mentions
Center for Computational Biology at JHU (RRID:SCR_016680) CCB at JHU data or information resource, portal, organization portal Center for Computational Biology as a joint research center in the McKusick-Nathans Institute of Genetic Medicine, spanning the School of Medicine, the Whiting School of Engineering, the Bloomberg School of Public Health, and the Krieger School of Arts & Sciences. Multidisciplinary center dedicated to research on genomics, genetics, DNA sequencing technology, and computational methods for DNA and RNA sequence analysis. center, computational, biology, genomics, genetics, DNA, RNA, sequence, technology, analysis has parent organization: Johns Hopkins University; Maryland; USA
is parent organization of: Centrifuge Classifier
SCR_016680 CCB at Johns Hopkins University, CCB at JHU, Center for Computational Biology at JHU, Center for Computational Biology at Johns Hopkins University 2026-02-17 10:03:27 1
GENCODE
 
Resource Report
Resource Website
5000+ mentions
Rating or validation data
GENCODE (RRID:SCR_014966) data or information resource, project portal, portal, dataset Human and mouse genome annotation project which aims to identify all gene features in the human genome using computational analysis, manual annotation, and experimental validation. human, mouse, genome, annotation, sequence, gene features, bio.tools is listed by: Debian
is listed by: bio.tools
is affiliated with: ENCODE
NHGRI 5U54HG004555;
Wellcome Trust WT098051
PMID:22955987 Free biotools:GENCODE https://bio.tools/GENCODE SCR_014966 ENCODE 2026-02-17 10:02:45 7700

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