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| Resource Name | Proper Citation | Abbreviations | Resource Type |
Description |
Keywords | Resource Relationships | |||||||||||||
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BWH Research Imaging Core Resource Report Resource Website |
BWH Research Imaging Core (RRID:SCR_002708) | BRIC | service resource, core facility, access service resource | Imaging Core facility that provides a comprehensive research imaging service to meet the needs of investigators and research subjects using imaging facilities at Brigham and Women's Hospital (BWH). A unique feature of BRIC is the complete anonymity of research subjects. Research image scheduling, image acquisition and image storage are all kept completely separate from BWH clinical Radiology systems. The BRIC provides the administrative infrastructure, customer service architecture and institutional support to promote investigative applications of imaging technologies. | consulting, contrast intravenous gad, data storage, functional brain imaging, human, small animal, mri, fmri, image, imaging |
is listed by: ScienceExchange is listed by: Eagle I is listed by: Brigham and Women's Hospital Labs and Facilities |
SciEx_8812 | http://harvard.eagle-i.net/i/0000012f-e501-b068-de5a-673e80000000 http://www.scienceexchange.com/facilities/bwh-research-imaging-core-bric-harvard |
SCR_002708 | Brigham and Women's Hospital Research Imaging Core, BWH Research Imaging Core (BRIC) | 2026-02-16 09:45:51 | 0 | |||||||
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Vietnam Era Twin Registry Resource Report Resource Website 1+ mentions |
Vietnam Era Twin Registry (RRID:SCR_008807) | VET Registry | patient registry, people resource, topical portal, portal, data or information resource | The Vietnam Era Twin (VET) Registry is a closed cohort composed of approximately 7,000 middle-aged male-male twin pairs both of whom served in the military during the time of the Vietnam conflict (1964-1975). The Registry is a United States Department of Veterans Affairs (VA) resource that was originally constructed from military records; the Registry has been in existence for almost 20 years. It is one of the largest national twin registries in the US and currently has members living in all 50 states. Initially formed to address questions about the long-term health effects of service in Vietnam, the Registry has evolved into a resource for genetic epidemiological studies of mental and physical health conditions. Several waves of mail and telephone surveys have collected a wealth of health-related information on Registry twins, referred to as members. In addition to twins, selected adult offspring of twins and the mothers of those offspring are also VET Registry members. More recent data collection efforts have focused on specific sets of twin pairs and have conducted detailed clinical or laboratory testing. Selected Vietnam Era Registry Research Studies: * Veteran Health Study * VETSA 2: A Longitudinal Study of Cognitive Aging * Alcoholism Course thought Midlife: A Twin Family Study and Offspring of Twins: G, E and GxE Risk for Alcoholism * GE: Offspring of Twins with Substance Use Disorder * Mechanisms Linking Depression to Cardiovascular Risk (Twins Heart Study 2) * Post-traumatic Stress Disorder and Cardiovascular Disease * Biological Markers for Post-traumatic Stress Disorder (T3) * Memory and the Hippocampus in Vietnam-era Twins with PTSD (Time 3) | twin, male, adult, gene, genetic, post-traumatic stress disorder, cardiovascular disease, child, mother, human, substance-related disorder, depressive disorder, memory, hippocampus, mental health, physical health, epidemiology |
has parent organization: U.S. Department of Veterans Affairs is parent organization of: Vietnam Era Twin Registry Biospecimen Repository |
Aging | nlx_144388 | SCR_008807 | 2026-02-16 09:47:16 | 2 | ||||||||
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Center for Comparative Medicine and Translational Research Resource Report Resource Website |
Center for Comparative Medicine and Translational Research (RRID:SCR_008299) | CCMTR | data or information resource, department portal, organization portal, portal | The mission of the CCMTR is to promote scientific discovery and facilitate its clinical application to achieve the goal of improving the health of animals and humans. The needs of the patients direct the emphasis of basic research, patient samples provide the critical resource to investigate the basis of disease, and patient participation in clinical studies is required to generate the evidence needed to apply new drugs, vaccines and technology to the broader patient population. Initiatives at the Center are designed to develop the multidisciplinary teams necessary to bring an idea from the lab to the patient. The Center is home to service cores that provide advanced technology, collect and store clinical patient samples, and perform clinical trials to validate new medical interventions. North Carolina State University''s College of Veterinary Medicine (CVM) is a dynamic community whose members are dedicated to preparing veterinarians and veterinarian scientists while advancing animal and human health from the cellular level through entire ecosystems. | drug, ecosystem, clinical, discovery, disease, health, human, patient, research, scientific, technology, vaccine, veterinary | has parent organization: North Carolina State University; North Carolina; USA | nif-0000-24380 | http://cvm.ncsu.edu/ccmtr/index.htm | SCR_008299 | 2026-02-16 09:47:09 | 0 | ||||||||
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Intramural Research Program Resource Report Resource Website 500+ mentions |
Intramural Research Program (RRID:SCR_012734) | NIA IRP | data or information resource, organization portal, portal | A research program of the NIA which focuses on neuroscience, aging biology, and translational gerontology. The central focus of the program's research is understanding age-related changes in physiology and the ability to adapt to environmental stress, and using that understanding to develop insight about the pathophysiology of age-related diseases. The IRP webpage provides access to other NIH resources such as the Biological Biochemical Image Database, the Bioinformatics Portal, and the Baltimore Longitudinal Study of Aging., THIS RESOURCE IS NO LONGER IN SERVICE. Documented on September 16,2025. | endocrinology, epidemiology, genetics, behavioral science, biochemistry, biomedical, cancer, cardiology, cell biology, clinical research, cognition, collaboration, gerontology, healthy, hematology, human, immunology, molecular biology, neurobiology, neurogenetics, neuroscience, oncology, osteoarthritis, pathophysiology, physiology, psychology, psychophysiology, research, rheumatology, age-related disease, healthy aging, alzheimer's disease, parkinson's disease, stroke, atherosclerosis, osteoarthritis, diabetes, cancer |
has parent organization: National Institute on Aging is parent organization of: NIA Mouse cDNA Project Home Page is parent organization of: Biological Biochemical Image Database is parent organization of: GERON is parent organization of: Baltimore Longitudinal Study of Aging (BLSA) |
Aging, Age-related disease, Healthy aging, Alzheimer's disease, Parkinson's disease, Atherosclerosis, Osteoarthritis, Cancer, Diabetes, Stroke | NIA | THIS RESOURCE IS NO LONGER IN SERVICE | nif-0000-09468 | SCR_012734 | National Institute on Aging Intramural Research Program, Intramural Research Program in the NIA, Intramural Research Program in the National Institute on Aging, NIA Intramural Research Program, Intramural Research Program of the National Institute on Aging | 2026-02-16 09:48:21 | 919 | |||||
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Human Genome Epidemiology Network Resource Report Resource Website 10+ mentions |
Human Genome Epidemiology Network (RRID:SCR_013117) | data or information resource, organization portal, portal | Human Genome Epidemiology Network, or HuGENet, is a global collaboration of individuals and organizations committed to the assessment of the impact of human genome variation on population health and how genetic information can be used to improve health and prevent disease. Its goals include: establishing an information exchange that promotes global collaboration in developing peer-reviewed information on the relationship between human genomic variation and health and on the quality of genetic tests for screening and prevention; providing training and technical assistance to researchers and practitioners interested in assessing the role of human genomic variation on population health and how such information can be used in practice; developing an updated and accessible knowledge base on the World Wide Web; and promoting the use of this knowledge base by health care providers, researchers, industry, government, and the public for making decisions involving the use of genetic information for disease prevention and health promotion. HuGENet collaborators come from multiple disciplines such as epidemiology, genetics, clinical medicine, policy, public health, education, and biomedical sciences. Currently, there are 4 HuGENet Coordinating Centers for the implementation of HuGENet activities: CDC''s Office of Public Health Genomics, Atlanta, Georgia; HuGENet UK Coordinating Center, Cambridge, UK; University of Ioannina, Greece; University of Ottawa , Ottawa, Canada. HuGENet includes: HuGE e-Journal Club: The HuGE e-Journal Club is an electronic discussion forum where new human genome epidemiologic (HuGE) findings, published in the scientific literature in the CDC''s Office of Public Health Genomics Weekly Update, will be abstracted, summarized, presented, and discussed via a newly created HuGENet listserv. HuGE Reviews: A HuGE Review identifies human genetic variations at one or more loci, and describes what is known about the frequency of these variants in different populations, identifies diseases that these variants are associated with and summarizes the magnitude of risks and associated risk factors, and evaluates associated genetic tests. Reviews point to gaps in existing epidemiologic and clinical knowledge, thus stimulating further research in these areas. HuGE Fact Sheets: HuGE Fact Sheets summarize information about a particular gene, its variants, and associated diseases. HuGE Case Studies: An on-line presentation designed to sharpen your epidemiological skills and enhance your knowledge on genomic variation and human diseases. Its purpose is to train health professionals in the practical application of human genome epidemiology (HuGE), which translates gene discoveries to disease prevention by integrating population-based data on gene-disease relationships and interventions. Students will acquire conceptual and practical tools for critically evaluating the growing scientific literature in specific disease areas. HUGENet Publications: Articles related to the HuGENet movement written by our HuGENet collaborators. HuGE Navigator: An integrated, searchable knowledge base of genetic associations and human genome epidemiology, including information on population prevalence of genetic variants, gene-disease associations, gene-gene and gene- environment interactions, and evaluation of genetic tests. HuGE Workshops: HuGENet has sponsored meetings and workshops with national and international partners since 2001. Available are detailed summaries, agendas or the ability to download speaker slides. HuGE Book: Human Genome Epidemiology: A Scientific Foundation for Using Genetic Information to Improve Health and Prevent Disease. (The findings and conclusions in this book are those of the author(s) and do not necessarily represent the views of the funding agency.) HuGENet Collaborators: HuGENet is interested in establishing collaborations with individuals and organizations working on population based research involving genetic information. HuGE Funding: Funding opportunities for specific population-based genetic epidemiology research projects are available. Research initiatives whose aims include assessing the prevalence of human genetic variation, the association between genetic variants and human diseases, the measurement of gene-gene or gene-environment interaction, and the evaluation of genetic tests for screening and prevention are compiled to create a posted listing. Additional information and application details can be found by clicking on the respective links. | epidemiology, gene, genetic, genetic variants, genome, articles, collaboration, disease, disease prevention, genomics, health promotion, human, human diseases | has parent organization: Centers for Disease Control and Prevention | nif-0000-00574 | SCR_013117 | HuGENet | 2026-02-16 09:48:17 | 25 | |||||||||
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Human Microbiome Project Resource Report Resource Website 100+ mentions |
Human Microbiome Project (RRID:SCR_012956) | HMP, NIH HMP, HMP1 | data or information resource, project portal, portal | NIH Project to generate resources to characterize the human microbiota and to analyze its role in human health and disease at several different sites on the human body, including nasal passages, oral cavities, skin, gastrointestinal tract, and urogenital tract using metagenomic and traditional approach to genomic DNA sequencing studies.HMP was supported by the Common Fund from 2007 to 2016. | generate, resource, human, body, microbiota, analyze, health, disease, metagenomic, DNA, sequesncing, data |
lists: Pathogen Portal lists: DNACLUST lists: QIIME lists: mothur lists: Greengenes lists: Ribosomal Database Project lists: DeconSeq lists: FragGeneScan lists: MetAMOS lists: MetaPhlAn lists: MetaPhyler lists: METAREP lists: PRINSEQ lists: TagCleaner lists: BioCyc lists: MG-RAST lists: Core Gene Evaluation Script lists: IMG System lists: RAST Server lists: GINGKO lists: inVUE lists: LEfSe lists: Metastats lists: MicrobiomeUtilities lists: Hypothesis Testing and Power Calculations for Comparing Metagenomic Samples from HMP lists: HMPTrees lists: Simrank lists: speciateIT lists: Unifrac lists: Fast-Unifrac lists: SitePainter lists: BMTagger lists: HUMAnN lists: Metapath lists: IMG System is related to: biobakery is related to: Integrative Human Microbiome Project is related to: MicrobiomeDB has parent organization: National Institutes of Health is parent organization of: HMP Data Analysis and Coordination Center |
NIH | nif-0000-25316 | https://www.hmpdacc.org/ihmp/ https://www.hmpdacc.org/hmp |
http://nihroadmap.nih.gov/hmp/ | SCR_012956 | Human Microbiome Project, NIH HMP, HMP1, HMP, NIH Human Microbiome Project | 2026-02-16 09:48:19 | 385 | |||||
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4D Nucleome Resource Report Resource Website 10+ mentions |
4D Nucleome (RRID:SCR_016925) | data or information resource, project portal, portal | Research project to understand the principles underlying nuclear organization in space and time, the role nuclear organization plays in gene expression and cellular function, and how changes in nuclear organization affect normal development and diseases. Portal provides free access to datasets, software packages, and protocols to advance biomedical research of nuclear architecture. Aims to develop and apply approaches to map the structure and dynamics of the human and mouse genomes. | nuclear, organization, gene, expression, cellular, function, normal, development, disease, map, structure, human, mouse, genome |
is listed by: NIDDK Information Network (dkNET) is related to: International Human Epigenome Consortium |
NIH Common Fund | PMID:28905911 | Public | SCR_016925 | 4D Nucleome Network; 4DN Web Portal, The 4D nucleome project, 4DN Portal | 2026-02-16 09:49:07 | 24 | |||||||
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GENCODE Resource Report Resource Website 5000+ mentions Rating or validation data |
GENCODE (RRID:SCR_014966) | data or information resource, dataset, project portal, portal | Human and mouse genome annotation project which aims to identify all gene features in the human genome using computational analysis, manual annotation, and experimental validation. | human, mouse, genome, annotation, sequence, gene features, bio.tools |
is listed by: Debian is listed by: bio.tools is affiliated with: ENCODE |
NHGRI 5U54HG004555; Wellcome Trust WT098051 |
PMID:22955987 | Free | biotools:GENCODE | https://bio.tools/GENCODE | SCR_014966 | ENCODE | 2026-02-16 09:48:40 | 7700 | |||||
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ProteomeTools Resource Report Resource Website 10+ mentions |
ProteomeTools (RRID:SCR_018535) | data or information resource, project portal, portal | Project for building molecular and digital tools from human proteome to facilitate biomedical research, drug discovery, personalized medicine and life science research. | Molecular tool, human proteome, proteome, human, peptide, data |
is related to: ProteomicsDB is related to: ProteomeXchange |
German Federal Ministry of Education and Research ; Alexander von Humboldt Foundation ; American Recovery and Reinvestment Act ; NHGRI RC2 HG005805; NIGMS R01 GM087221; NCRR S10 RR027584; NIGMS P50 GM076547; European Research Council ; Swiss National Science Foundation |
PMID:28135259 | Free, Freely available | http://www.proteometools.org | SCR_018535 | 2026-02-16 09:49:31 | 21 | |||||||
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AcceGen Biotech Resource Report Resource Website 1+ mentions |
AcceGen Biotech (RRID:SCR_017274) | material resource, biomaterial supply resource, cell repository | AcceGen offers most complete human and animal cell products and cell/molecular biology services for life science researchers worldwide. Cell line collections include primary cells, tumor cell lines, transfected stable cell lines, stem cells and immortalized cell lines. miRNA agomir/antagomir, nucleic acid kits, enzymes and custom cell/molecular biology services. | Company, AcceGen, human, animal, cell, cell lines, product, service, cell culture | SCR_017274 | 2026-02-16 09:49:12 | 1 | ||||||||||||
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Human Mouse Disease Connection Resource Report Resource Website 1+ mentions |
Human Mouse Disease Connection (RRID:SCR_017522) | HMDC | service resource, data or information resource, database | Collection of published and potential mouse models of human disease, discovery of candidate genes and investigation of phenotypic similarity between mouse models and human patients. Mouse mutation, and phenotype and disease model data from Mouse Genome Informatics database are integrated with human gene to disease relationships from the National Center for Biotechnology Information and Online Mendelian Inheritance in Man and human disease to phenotype relationships from the Human Phenotype Ontology. | Collection, mouse, model, human, disease, discovery, candidate, gene, phenotypic, similarity, patient |
has parent organization: Mouse Genome Informatics (MGI) works with: Human Phenotype Ontology works with: OMIM works with: NCBI |
Free, Freely available | SCR_017522 | Human - Mouse: Disease Connection | 2026-02-16 09:49:15 | 1 | ||||||||
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RegulomeDB Resource Report Resource Website 100+ mentions |
RegulomeDB (RRID:SCR_017905) | service resource, data or information resource, database | Database that annotates SNPs with known and predicted regulatory elements in intergenic regions of H. sapiens genome. Known and predicted regulatory DNA elements include regions of DNAase hypersensitivity, binding sites of transcription factors, and promoter regions that have been biochemically characterized to regulation transcription. Source of these data include public datasets from GEO, ENCODE project, and published literature. | Annotate, SNP, regulatory, DNA, element, intergenic, region, human, genome, sequence, DNAase, hypersensitivity, binding, site, transcription, factor, promoter, region, data, FASEB list | NHGRI U54 HG 004558; Beta Cell Consortium |
PMID:22955989 | Free, Freely available | SCR_017905 | 2026-02-16 09:49:22 | 123 | |||||||||
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Network for Pancreatic Organ Donors with Diabetes Resource Report Resource Website 100+ mentions Rating or validation data |
Network for Pancreatic Organ Donors with Diabetes (RRID:SCR_014641) | nPOD | tissue bank, material resource, biomaterial supply resource | A collaborative research project that supports nPOD approved diabetes investigators by freely providing rare and difficult-to-obtain tissues from type 1 and type 2 diabetes donors. Interested researchers are encouraged to apply to obtain nPOD tissues, or to request access to analyze cases in the nPOD Online Pathology site. Interested donors can contact nPOD directly for more information. | biosample, diabetes, type 1 diabetes, type 2 diabetes, donor, human, tissue, tissue supplier, pancreas, biomaterial supply resource, organization | is listed by: NIDDK Information Network (dkNET) | Type 1 diabetes, Diabetes | Public, Available to the research community, Must be an approved nPOD investigator to receive samples | SCR_014641 | Network for Pancreatic Organ Donors with Diabetes (nPOD), The Network for Pancreatic Organ Donors with Diabetes | 2026-02-16 09:48:39 | 177 | |||||||
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Geno2MP Resource Report Resource Website 1+ mentions |
Geno2MP (RRID:SCR_016872) | Geno2MP | service resource, data or information resource, database | Collection of phenotypic profiles for affected individuals and, for unaffected individuals, the phenotypic profile of their affected. Collaborative, shared resource for the human genetics community. | data, collection, Mendelian, phenotype, affected, individuals, profile, human, genetics |
is used by: MARRVEL is listed by: OMICtools |
University of Washington Center for Mendelian Genomics ; Seattle ; WA |
Free, Available for download, Freely available | SCR_016872 | Geno2MP, 2 Mendelian Phenotype, The Genotype 2 Mendelian Phenotype database | 2026-02-16 09:49:06 | 2 | |||||||
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NeuroPsyDoctor8 Resource Report Resource Website |
NeuroPsyDoctor8 (RRID:SCR_005471) | NeuroPsyDoctor8 | data or information resource, blog, narrative resource | Called The Marquis de fMRI by Dr. Anon, NeuroPsyDoctor8 is about neurolaw and related moral cognition research, by someone who has a forensic psych type biz in NYC & then decided to pursue a neuropsych PhD. Now she uses fMRI and a side of bourbon to figure it all out. | neurolaw, cognition, neuropsychiatry, fmri, forensic, human, research, neuroscience, psychiatry, neuroethics | nlx_144588 | SCR_005471 | 2026-02-16 09:46:40 | 0 | ||||||||||
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Atlas of the Human Brain Stem Resource Report Resource Website 1+ mentions |
Atlas of the Human Brain Stem (RRID:SCR_007275) | data or information resource, atlas | In this atlas you can view axial sections stained for cell bodies or for nerve fibers, at six rostro-caudal levels of the human brain stem. The creators of the site encourage the use of the data and it is available freely, but ask that they be contacted before any use. This site contains a series of axial sections stained for cell bodies or fibers at six rostro-caudal levels of the human brain stem. Sections are labeled for approximately 50 structures and are searchable through a web interface. For each level, a fiber and cell stain is provided. Labels may be turned on or off. | fiber stain, brain section, brainstem, cell stain, human | has parent organization: Michigan State University; Michigan; USA | nif-0000-00015 | SCR_007275 | Atlas of the Human Brain Stem | 2026-02-16 09:46:56 | 1 | |||||||||
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AIDS.gov Blog Resource Report Resource Website |
AIDS.gov Blog (RRID:SCR_007156) | AIDS.gov Blog | data or information resource, blog, narrative resource | The AIDS.gov blog serves as a forum to foster public discussion on using new media effectively in response to HIV/AIDS, as well as HIV/AIDS research and policies. Along with weekly new media posts, the blog features other AIDS.gov-authored posts, guest posts, cross-posts from the White House Office of National AIDS Policy blog and the CDC Health Protection Perspectives blog, PEPFAR blog, and posts from the National Institute of Allergies and Infectious Diseases'' (NIAID) Division of AIDS. A large number of Federal agencies and programs are engaged in HIV/AIDS prevention, testing, treatment, policy, and research efforts in the United States. AIDS.gov serves as a gateway for information about these Federal efforts, with a focus on domestic programs. Since the launch of AIDS.gov on December 1, 2006 (World AIDS Day), there has been a growing interest in using new media tools to disseminate information about HIV/AIDS and improve prevention, testing, treatment, and research outcomes. AIDS.gov created this blog to address that interest, and has since expanded content areas to include key US Government HIV/AIDS-related research and policy posts, among other topics. | aids, human, human immunodeficiency virus | has parent organization: AIDS.gov | nlx_144417 | SCR_007156 | 2026-02-16 09:46:54 | 0 | |||||||||
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Pennsylvania University Perelman School of Medicine Stem Cell and Xenograft Core Facility Resource Report Resource Website 10+ mentions |
Pennsylvania University Perelman School of Medicine Stem Cell and Xenograft Core Facility (RRID:SCR_010035) | Pennsylvania University Perelman School of Medicine SCXC | tissue bank, training service resource, core facility, access service resource, material resource, organism supplier, service resource, biomaterial supply resource | Offers in vivo services specializing in immunodeficient and xenograft models (PDX, humanized immune system). Facility has dedicated BSL2 barrier space equipped with optical imaging, for applications ranging from immunotherapy, cancer biology, infectious diseases and regenerative medicine. Offers services centered around repository of live and fully annotated cells from adult patients with hematologic malignancies (AML, ALL, MPN, MDS), and hematopoietic stem/progenitor cells from healthy donors (BM, CB, and FL). | xenograft, ABRF, USEDit, healthy donor, umbilical, cord, tissue, bank, human, hematopoietic, malignancy, service, whole, bone, marrow, blood, sorter, leukemia, imaging |
is listed by: Eagle I is listed by: ABRF CoreMarketplace is related to: USEDit has parent organization: University of Pennsylvania; Philadelphia; USA |
nlx_156506, ARBF_1384 | https://coremarketplace.org?citation=1&FacilityID=1384 | http://eagle-i.itmat.upenn.edu/i/0000013b-afd0-cc4c-83a0-df0880000000 | SCR_010035 | Penn Stem Cell and Xenograft Core (SCXC), Penn Stem Cell and Xenograft Core, Penn Stem Cell & Xenograft Core | 2026-02-16 09:47:39 | 38 | ||||||
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NIMH Director's Blog Resource Report Resource Website |
NIMH Director's Blog (RRID:SCR_008841) | data or information resource, blog, narrative resource | Blog by the NIMH Director, Thomas R. Insel, M.D. Users may sort posts by topic and/or subsribe to the RSS Feed, http://www.nimh.nih.gov/site-info/feed-directors-blog.atom | attention deficit-hyperactivity disorder, autism, bipolar disorder, borderline personality disorder, depression, depressive disorder, eating disorder, obsessive-compulsive disorder, post-traumatic stress disorder, schizophrenia, woman, mental health, child, adolescent, research, military, trauma, diversity, ethnicity, genetics, aids, hiv, imaging, medication, suicide, treatment, human, anxiety disorder, prevention | has parent organization: National Institute of Mental Health | NIMH | nlx_146220 | SCR_008841 | National Institute of Mental Health Directors Blog, National Institute of Mental Health Director's Blog, NIMH Directors Blog | 2026-02-16 09:47:17 | 0 | ||||||||
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Tennenbaum Center for the Biology of Creativity Resource Report Resource Website |
Tennenbaum Center for the Biology of Creativity (RRID:SCR_000668) | data or information resource, organization portal, portal | The purpose of this center is to study the molecular, cellular, systems and cognitive mechanisms that result in cognitive enhancements and explain unusual levels of performance in gifted individuals, including extraordinary creativity. Additionally, by understating the mechanisms responsible for enhancements in performance we may be better suited to intervene and reverse disease states that result in cognitive deficits. One of the key topics addressed by the Center is the biological basis of cognitive enhancements, a topic that can be studied in human subjects and animal models. In the past much of the focus in the brain sciences has been on the study of brain mechanisms that degrade cognitive performance (for example, on mutations or other lesions that cause cognitive deficits). The Tennenbaum Center for the Biology of Creativity at UCLA enables an interdisciplinary team of leading scientists to advance knowledge about the biological bases of creativity. Starting with a pilot project program, a series of investigations was launched, spanning disciplines from basic molecular biology to cognitive neuroscience. Because the concept of creativity is multifaceted, initial efforts targeted refinement of the component processes necessary to generate novel, useful cognitive products. The identified core cognitive processes: 1.) Novelty Generation the ability to flexibly and adaptively generate products that are unique; 2.) Working Memory and Declarative Memory the ability to maintain, and then use relevant information to guide goal-directed performance, along with the capacity to store and retrieve this information; and 3.) Response Inhibition the ability to suppress habitual plans and substitute alternate actions in line with changing problem-solving demands. To study the basic mechanisms underlying these complex brain functions we use translational strategies. Starting from foundational studies in basic neuroscience, we forged an interdisciplinary strategy that permits the most advanced techniques for genetic manipulation and basic neurobiological research to be applied in close collaboration with human studies that converge on the same core cognitive processes. Our integrated research program aims to reveal the genetic architecture and fundamental brain mechanisms underlying creative cognition. The work holds enormous promise for both enhancing healthy cognitive performance and designing new treatments for diverse cognitive disorders. Sponsors: The Tennenbaum Center for the Biology of Creativity was inspired by the vision and generosity of Michael Tennenbaum. | generation, genetic, animal, biological, brain, brain science, cellular, cognitive, cognitive deficit, cognitive disorder, cognitive neuroscience, creativity, declarative memory, disease, habitual, human, inhibition, mechanism, memory, model, molecular, molecular biology, neurobiological, performance, response, working memory | THIS RESOURCE IS NO LONGER IN SERVICE | nif-0000-10497 | SCR_000668 | UCLA CBC | 2026-02-16 09:45:19 | 0 |
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