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http://www.scienceexchange.com/facilities/gnarus-systems

Gnarus Systems is pleased to offer cat-SAR; a peer-reviewed in silico toxicity prediction expert system. The cat-SAR system associates 2-dimensional chemical fragments with active or inactive compounds in a learning set. Unlike many other approaches, cat-SAR is transparent and model parameter selection is controlled by the user. As such, the approach is sharable and allows unrestricted user scrutiny, intervention and model optimization throughout the SAR modeling process. This rationale negates any a priori requirements that a given set of data must fit the attributes of a predefined and often proprietary modeling process. The cat-SAR system essentially ??????????????????learns???????????? about the biological activity of chemicals by analyzing ??????????????????learning sets???????????? of data. These are endpoint specific databases of toxicological or pharmacological chemical activity (e.g., carcinogens and developmental toxicants) that are assembled by us or others. Currently, we have validated and usable learning sets for a variety of health endpoints including cancer, anticancer, genotoxicity, developmental toxicity, and chemical allergy. Currently, cat????????????SAR models are available for: Rats, mice, and rodents carcinogenesis including gender-specific submodels Mammary Cancer in Rodents Tissue/organ specific carcinogenesis for 12 tumor types Salmonella mutagenicity (i.e. the Ames Assay) Developmental Toxicity Allergic Contact Dermatitis Respiratory Hypersensitivity Mouse Local Lymph Node Assay Ocular toxicity Estrogen mimics based on the E-SCREEN assay Anticancer activity to several different breast cancer cell lines

Proper citation: Gnarus Systems (RRID:SCR_012681) Copy   

•   Source: SciCrunch Registry

http://www.scienceexchange.com/facilities/3scan

3Scan uses the cutting edge technology of the KESM (Knife Edge Scanning Microscope) to automatically section and image samples. Knife-edge scanning, introduced in the KESM instrument, not only preserves image registration throughout the depth of the specimen block but also isolates the tissue above the knife from that below to eliminate undesirable events (back-scattering of light and bleaching of fluorescent-stained tissue below the knife). Using the KESM, 3Scan is able to scan a one cc^3 block of tissue (for example, a whole mouse brain) at submicron resolution in under 100 hours. With this resolution (a voxel size of 0.6 um x 0.7 um x 1.0 um) 3Scan is able to show cell scale phenomena in the context of a compete organ. In the example of a whole mouse brain this means that 3Scan is able to accurately model every neuron in the mouse brain sample.

Proper citation: 3Scan (RRID:SCR_012685) Copy   

•   Source: SciCrunch Registry

http://www.scienceexchange.com/facilities/editorians-international

Provide editing of scientific-, technical, and other scholarly papers. Non-native-speakers of English are welcome.

Proper citation: Editorians International (RRID:SCR_012612) Copy   

•   Source: SciCrunch Registry

http://www.scienceexchange.com/facilities/waisman-biomanufacturing

THIS RESOURCE IS NO LONGER IN SERVICE. Documented on April 15,2024. With broad and comprehensive capabilities, Waisman Biomanufacturing is uniquely situated and highly qualified to lead clients through the complex process of bringing a novel therapeutic into the clinic. Integral to any product campaign is a well thought-out product development plan. You can rely on our business manager and team of project leaders to work closely with you to maintain an on-going flow of communication and develop a time and cost effective plan that meets your needs. Utilizing our expertise in both Quality Assurance/Control and Process Development/Manufacture we can translate your bench top process to a large scale manufacturing process. Using this strategy Waisman routinely produces cGMP grade material qualified for clinical trials for a wide variety of applications.

Proper citation: Waisman Biomanufacturing (RRID:SCR_012583) Copy   

•   Source: SciCrunch Registry

http://www.scienceexchange.com/facilities/neuroimage

THIS RESOURCE IS NO LONGER IN SERVICE. Documented on May 15, 2024. Commercial neuroimaging organization that provides services for compound profiling, biostatistics, computed tomography, and data modeling.

Proper citation: NeuroImage (RRID:SCR_012707) Copy   

•   Source: SciCrunch Registry

http://www.scienceexchange.com/facilities/flow-paradigm

THIS RESOURCE IS NO LONGER IN SERVICE. Documented on October 30,2023. ICCE certified instructors with 20 years experience in flow cytometry and assay development can deliver basic, intermediate, and advanced training tailored to your needs. We can ensure rapid assay development and implementation, using theoretical and hands-on training conducted at your site, using your assays and your instruments.

Proper citation: Flow Paradigm (RRID:SCR_012165) Copy   

•   Source: SciCrunch Registry

https://www.lonza.com/cell-and-gene/viral-vectors

Contract research organization for gene therapy product development. Services include adenoviral vectors, AAV vectors and lentiviral vectors and range from cell line optimization and vector development to process development and cGMP manufacturing through product release testing.

Proper citation: Lonza Viral Based Therapeutics (RRID:SCR_012164) Copy   

•   Source: SciCrunch Registry

http://www.scienceexchange.com/facilities/affina-biotechnologies-inc

THIS RESOURCE IS NO LONGER IN SERVICE. Documented on October 30,2023. Affina Biotechnologies is dedicated to excellence in helping our customers develop measurements of activities, kinetics and affinities of interactions and concentrations of biomolecules. We offer a unique mix of label-free and label-dependent assay technologies supported by scientific and technical expertise and a wide range of instrumentation.

Proper citation: Affina Biotechnologies (RRID:SCR_012207) Copy   

•   Source: SciCrunch Registry

http://www.scienceexchange.com/facilities/integrated-technology-enterprise-inc

THIS RESOURCE IS NO LONGER IN SERVICE. Documented on October 30,2023. We will design and produce DNA constructs for any purpose: Mutations/Deletions Knockout/Transgenic constructs Epitope tags & Fusion proteins Protein expression constructs Viral gene delivery constructs RNAi & related constructs Cost is generally about $300 per construct Turnaround time usually 5 business days

Proper citation: Integrated Technology Enterprise Inc (RRID:SCR_012186) Copy   

•   Source: SciCrunch Registry

http://www.scienceexchange.com/facilities/akesogen-inc

THIS RESOURCE IS NO LONGER IN SERVICE. Documented on October 30, 2023. AKESOgen is a biomarker, genomics and pharmacogenomics contract research organization that services the academic, pharmaceutical, biotechnology and agricultural sectors. AKESOgen performs biomarker profiling and genomics services utilizing different types of markers (e.g. DNA, RNA, methylation) for the R&D market. AKESOgen establishes and validates biomarkers in the Clinical Trials arena. AKESOgen provides expertise in biobanking. AKESOgen is CLIA certified.

Proper citation: AKESOgen Inc. (RRID:SCR_012180) Copy   

•   Source: SciCrunch Registry

https://www.richmanchemical.com/custom-synthesis/?gclid=Cj0KCQjwqP2pBhDMARIsAJQ0Czp_deoOcbt7aBksAjDKz7wAtJ05S7UicyoFk9d0pH7Tmz4h21cw1OEaAl3cEALw_wcB

Richman Chemical offers a full range of custom synthesis and manufacturing services to life science and chemical industries. Our technical capabilities include: complex multi-step organic synthesis, emulsion or solution polymerization, inorganic custom synthesis (including organometallics), electronic chemicals, stereochemically pure compounds For our pharmaceutical clients, we also provide drug product formulation, compounding, and packaging.

Proper citation: Richman Chemical (RRID:SCR_012183) Copy   

•   Source: SciCrunch Registry

http://www.scienceexchange.com/facilities/molecule-inc

THIS RESOURCE IS NO LONGER IN SERVICE. Documented on October 30,2023. Molecule serves the needs of your businesses, both large and small. We are based in Silicon Valley with local and international labs. We are a team of experts who have worked for world-class companies over 2 decades and provide service in a wide range of chemistry, formulation and new technology development areas of medical device and drug control release products. We provide both contract work and consulting service in wet chemistries (customer design and synthesis) and formulation development. We have spent so much time to accumulate experience so your work can be developed in the shortest amount of time.

Proper citation: Molecule Inc. (RRID:SCR_012182) Copy   

•   Source: SciCrunch Registry

https://www.acellera.com/

Acellera is company focused on developing high-throughput molecular dynamics techniques that deliver solutions for estimating common physico-chemical properties such as binding affinities, kinetics, poses and pathways with validated accuracy.Company mission is to accelerate transition to rational, computerized drug discovery via simulations and machine learning.

Proper citation: Acellera (RRID:SCR_012200) Copy   

•   Source: SciCrunch Registry

http://www.scienceexchange.com/facilities/university-of-colorado-at-boulder

A portal for the core labs and facilities at the University of Colorado at Boulder.

Proper citation: University of Colorado at Boulder Labs and Facilities (RRID:SCR_001054) Copy   

•   Source: SciCrunch Registry

http://www.ezbioresearch.com

A biotechnology company that develops, manufactures and distributes molecular biology tool kits and laboratory consumable products. Services include DNA and RNA microarrays, PCR and transgenic genotyping, and DNA/RNA analysis and quality control.

Proper citation: EZ BioResearch (RRID:SCR_001050) Copy   

•   Source: SciCrunch Registry

https://gtac.wustl.edu

Genome Access Technology Center at the McDonnell Genome Institute offers comprehensive next generation sequencing, microarray, PCR and Bioinformatic services. In addition to generating high quality genomic, transcriptomic, and proteomic data, performs data analysis and provides technological support to users. Full service facility, from hypothesis to publication. Offers advanced analysis of microarray data. Provides free initial consultation to discuss project and offers several tiers of analysis packages to best suit your needs. NGS equipment includes NovaSeqs, Seqwell II, Oxford. Microarray expression and genotyping - all platforms.

Proper citation: Washington University School of Medicine Genome Technology Access Center Core Facility (RRID:SCR_001030) Copy   

•   Source: SciCrunch Registry

http://www.phalanxbiotech.com/

Group service that provides expression profiling products and services. They manufacture DNA microarrays for gene expression and microRNA profiling.

Proper citation: Phalanx Biotech Group (RRID:SCR_002717) Copy   

•   Source: SciCrunch Registry

http://www.umc.edu/Administration/Centers_and_Institutes/Center_for_Psychiatric_Neuroscience/Core_Research_Resources.aspx

Core facility that provides access to psychiatrically characterized post-mortem brain specimens, state-of-the-art equipment, cutting-edge technologies and the technical advice of highly trained faculty members who serve as Core Directors. The sophisticated imaging systems and biotechnologically advanced molecular core resources are provided on a shared-use basis to CPN and UMMC researchers. The CPN Research Resources Cores include the Human Brain Collection Core, Animal Core, Imaging Core, Molecular Biology Core, and Information Technologies Core.

Proper citation: UMMC Center for Psychiatric Neuroscience Labs and Facilities (RRID:SCR_002688) Copy   

•   Source: SciCrunch Registry

http://www.scienceexchange.com/facilities/igentbio

A commercial facility handling induced pluripotent stem cell (iPSC) generation, cellular characterization, teratoma formation, karyotyping, and KO-mouse generation.

Proper citation: iGentBio (RRID:SCR_002722) Copy   

•   Source: SciCrunch Registry

https://www.isu.edu/hp/facilities/

ISU has many facilities that are available for educational and research use. These include Idaho Accelerator Center in Physics Department and Nuclear Science research laboratory in Nuclear Engineering and Health Physics Department.

Proper citation: Idaho State University Labs and Facilities (RRID:SCR_011065) Copy   

•   Source: SciCrunch Registry