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SciCrunch Registry is a curated repository of scientific resources, with a focus on biomedical resources, including tools, databases, and core facilities - visit SciCrunch to register your resource.

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Resource Name Proper Citation Abbreviations Resource Type Description Keywords Resource Relationships Related Condition Funding Defining Citation Availability Website Status Alternate IDs Alternate URLs Old URLs Parent Organization Resource ID Synonyms Record Last Update Mentions Count
MAFFT
 
Resource Report
Resource Website
10000+ mentions
MAFFT (RRID:SCR_011811) MAFFT software application, data processing software, software toolkit, image analysis software, software resource, alignment software Software package as multiple alignment program for amino acid or nucleotide sequences. Can align up to 500 sequences or maximum file size of 1 MB. First version of MAFFT used algorithm based on progressive alignment, in which sequences were clustered with help of Fast Fourier Transform. Subsequent versions have added other algorithms and modes of operation, including options for faster alignment of large numbers of sequences, higher accuracy alignments, alignment of non-coding RNA sequences, and addition of new sequences to existing alignments. alignment, amino acid, nucleotide, sequence, DNA, sequence alignment, bio.tools is listed by: OMICtools
is listed by: Debian
is listed by: bio.tools
is listed by: SoftCite
EMBL ;
Ministry of Education ;
Culture ;
Sports ;
Science and Technology of Japan
PMID:12136088
PMID:17118958
PMID:16362903
PMID:15661851
PMID:18439255
PMID:23023983
DOI:10.1093/bib/bbn013
biotools:MAFFT, OMICS_00979 https://www.ebi.ac.uk/Tools/msa/mafft/
https://www.genome.jp/tools-bin/mafft
https://myhits.isb-sib.ch/cgi-bin/mafft
https://bio.tools/MAFFT
https://sources.debian.org/src/mafft/
SCR_011811 Multiple Alignment using Fast Fourier Transform, MAFFT version 5, MAFFT version 7 2026-02-16 09:48:02 22450
AdapterRemoval
 
Resource Report
Resource Website
500+ mentions
AdapterRemoval (RRID:SCR_011834) software application, data processing software, sequence analysis software, data analysis software, software resource Software program to remove residual adapter sequences from next generation sequencing reads. Used for cleaning of next-generation sequencing reads. AdapterRemoval v2 introduces improvements in throughput, through use of single instruction, multiple data (SIMD; SSE1 and SSE2) instructions and multi-threading support; handles datasets containing reads or read-pairs with different adapters or adapter pairs; provides simultaneous demultiplexing and adapter trimming; has ability to reconstruct adapter sequences from paired-end reads for poorly documented data sets; provides native gzip and bzip2 support. cleaning of next-generation sequencing reads, remove residual adapter sequences, adapter, sequence, residual, next generation sequencing reads, is listed by: OMICtools
is listed by: Debian
Danish National Research Foundation ;
Lundbeck Foundation Grant ;
Marie Curie International Outgoing Fellowship within the 7th European Community Framework Programme ;
Danish Council for Independent Research
PMID:22748135
PMID:26868221
DOI:10.1186/s13104-016-1900-2
Free, Available for download, Freely available OMICS_01081 https://sources.debian.org/src/adapterremoval/ http://code.google.com/p/adapterremoval/, https://github.com/slindgreen/AdapterRemoval, https://sources.debian.org/src/adapterremoval/ SCR_011834 AdapterRemoval v2 2026-02-16 09:48:00 675
Axe
 
Resource Report
Resource Website
1+ mentions
Axe (RRID:SCR_015984) software application, data processing software, software toolkit, sequence analysis software, data analysis software, software resource Software for sequencing data analysis and demultiplexing. It can be used in situations where sequence reads contain the barcodes that uniquely distinguish samples. software, tool, sequence, analysis, barcode, demultiplexing is listed by: Debian
is listed by: OMICtools
Free, Freely available, Available for download OMICS_19788 https://readthedocs.org/projects/axe-demultiplexer/
https://sources.debian.org/src/baitfisher/
SCR_015984 Axe-demultiplexer 2026-02-16 09:48:55 1
Bamtools
 
Resource Report
Resource Website
100+ mentions
Bamtools (RRID:SCR_015987) software application, data processing software, software toolkit, data analysis software, data management software, software resource Software that provides both a C++ API and a command-line toolkit for reading, writing, and manipulating genome sequence alignment files in the BAM and SAM formats. It is used for research analysis and management of data produced by sequencing technologies. c++, api, sam, bam genome, sequence, alignment, data, analysis, management, command, manipulation, binary, map, bio.tools is listed by: Debian
is listed by: bio.tools
is listed by: OMICtools
NHGRI R01 HG004719;
NHGRI RC2 HG005552
PMID:21493652
DOI:10.1093/bioinformatics/btr174
biotools:bamtools, OMICS_11315 https://bio.tools/bamtools
https://sources.debian.org/src/bamtools/
SCR_015987 API:Application Programming Interface, BAM:Binary Alignment Map, SAM:Sequence Alignment Map 2026-02-16 09:48:55 324
G-Anchor
 
Resource Report
Resource Website
1+ mentions
G-Anchor (RRID:SCR_016046) G-Anchor software application, data processing software, sequence analysis software, data analysis software, image analysis software, software resource, alignment software Software for comparing large genomes and exploiting highly conserved sequences as evolutionary-stable "anchors". The pipeline maps a newly sequenced genome (assembled in scaffolds) on a reference genome without the need of a supercomputer. anchor, comparison, scaffold, whole genome, alignment, sequence, mapping, anchoring, highly conserved elements, hce, evolution HPC Wales ;
Biotechnology and Biological Sciences Research Council BB/J010170/1
Free, Available for download SCR_016046 G-Anchor: A novel approach for cross-species comparison 2026-02-16 09:48:59 1
Blixem
 
Resource Report
Resource Website
1+ mentions
Blixem (RRID:SCR_015994) software application, data processing software, image analysis software, software resource, alignment software Software for sequence alignments that displays multiple match sequences aligned against a single genomic reference sequence. It can be used for manipulation, display and annotation of genomic data, to check the quality of an alignment, to find missing/misaligned sequence, and to identify splice sites and polyA sites. software, sequence, alignment, annotation, genomic, reference, data, display, manipulation, DNA is related to: SEQtools
has parent organization: Wellcome Trust Sanger Institute; Hinxton; United Kingdom
Wellcome Trust Grant 098051;
NHGRI U54 HG00455
PMID:26801397 Free, Available for download SCR_015994 SEQtools Blixem 2026-02-16 09:48:55 2
HiLive
 
Resource Report
Resource Website
HiLive (RRID:SCR_016134) software application, data processing software, sequence analysis software, data analysis software, software resource Software tool for performing read mapping that maps Illumina HiSeq sequencer read alignments when they are produced. Used in Next Generation Sequencing in time critical, clinical applications. perform, read, mapping, sequence, alignment, analysis, Illumina, time, critical, clinical, application is listed by: Debian
is listed by: OMICtools
the German Federal Ministry of Health IIA5-2512-FSB-725 PMID:27794555 Free, Available for download OMICS_13393 https://sources.debian.org/src/hilive/ https://sourceforge.net/projects/hilive/ SCR_016134 2026-02-16 09:48:57 0
FSA
 
Resource Report
Resource Website
1+ mentions
FSA (RRID:SCR_016114) FSA software application, data processing software, image analysis software, software resource, alignment software Software for a statistical multiple sequence alignment algorithm which uses a "distance-based" approach to align homologous protein, RNA or DNA sequences. The GUI, MAD (Multiple Alignment Display), can display the intermediate alignments produced by FSA, where each character is colored according to the probability that it is correctly aligned. multiple, sequence, alignment, algorithm, distance, approach, homologous, protein, DNA, RNA, acurate, fast is listed by: Debian
is listed by: OMICtools
has parent organization: University of California at Berkeley; Berkeley; USA
PMID:19478997 Free, available for download https://sources.debian.org/src/fsa/ SCR_016114 Fast Statistical Alignment, FSA: Fast Statistical Alignment 2026-02-16 09:48:59 3
GARLI
 
Resource Report
Resource Website
100+ mentions
GARLI (RRID:SCR_016117) GARLI software application, data processing software, data analysis software, software resource Software application for inferring phylogenetic trees and analysis of molecular sequence data using the maximum-likelihood criterion. It implements nucleotide, amino acid and codon-based models of sequence evolution. inference, phylogenetic, tree, analysis, molecular, sequence, data, maximum, likelihood, criterion, nucleotide, amino acid, codon, model, evolution is listed by: Debian
is listed by: OMICtools
Free, Available for download, Freely available OMICS_04234 https://code.google.com/archive/p/garli/
https://sources.debian.org/src/garli/
SCR_016117 Genetic Algorithm for Rapid Likelihood Inference 2026-02-16 09:48:57 279
DIAMOND
 
Resource Report
Resource Website
100+ mentions
DIAMOND (RRID:SCR_016071) software application, data processing software, sequence analysis software, data analysis software, software resource Software that performs sequence alignment for protein and translated DNA searches and functions. Used for high performance analysis of big sequence data, protein-protein search, and DNA-protein search. sequence, aligner, high, performance, analysis, big, data, protein, DNA, bio.tools is listed by: bio.tools
is listed by: Debian
is listed by: OMICtools
has parent organization: University of Tubingen; Tubingen; Germany
PMID:25402007
DOI:10.1038/nmeth.3176
Free, Available for download OMICS_08011, biotools:diamond https://bio.tools/diamond
https://sources.debian.org/src/diamond-aligner/
SCR_016071 2026-02-16 09:48:56 386
Glam2
 
Resource Report
Resource Website
50+ mentions
Glam2 (RRID:SCR_016129) Glam2 software application, data processing software, software toolkit, sequence analysis software, data analysis software, software resource Software package for finding novel, gapped (recurring, variable-length patterns) motifs in related groups of DNA or protein sequences (sample output from sequences). Used to perform motif based sequence discovery for gapped motifs on DNA or protein datasets. motif, analysis, sequence, find, amino acid, nucleotide, set, alignment, gapped, recurring, variable, letnght, pattern, DNA, protein, output, discovery, dataset is related to: MEME Suite - Motif-based sequence analysis tools NIGMS R01 GM103544 PMID:18437229 Free, Freely available for non-commercial use http://meme-suite.org/ SCR_016129 Glam2: Gapped local alignment of motifs 2 2026-02-16 09:48:57 72
E-mem
 
Resource Report
Resource Website
10+ mentions
E-mem (RRID:SCR_016081) E-mem software application, data processing software, image analysis software, software resource, alignment software, standalone software Software for an efficient maximal exact match (MEM) computation program that does not use full text indexes, uses less space and is amenable to parallelization. It can be used as a stand alone application or a drop-in replacement for MUMmer3 system for rapidly aligning entire genomes. efficient, maximal, exact, match, compute, program, algorithm, application, sequence, alignment is listed by: Debian
is listed by: OMICtools
has parent organization: Department of Computer Science; University of Western Ontario; London; Ontario; Canada
Natural Sciences and Engineering Research Council of Canada (NSERC) Discovery Grant R3143A01 (L.I.). PMID:25399029 Free, Available for download OMICS_08451 https://github.com/lucian-ilie/E-MEM
https://sources.debian.org/src/e-mem/
SCR_016081 E-mem: Efficient-maximal exact match 2026-02-16 09:48:57 12
GenomeTools
 
Resource Report
Resource Website
100+ mentions
GenomeTools (RRID:SCR_016120) software application, data processing software, software toolkit, sequence analysis software, data analysis software, software resource Software toolkit for biological sequence analysis and -presentation combined into a single binary. It is used for genome analysis, efficient processing of structured genome annotations and contains binaries for sequence and annotation handling, sequence compression, index structure generation and access, annotation visualization. analysis, genome, annotate, sequence, compress, visualization, single, binary, combine, structure, efficient is listed by: Debian
is listed by: OMICtools
PMID:24091398 Free, Available for download OMICS_16119 https://sources.debian.org/src/genometools/ SCR_016120 GenomeTool, Genome Tools, Genome Tool 2026-02-16 09:48:57 131
Circlator
 
Resource Report
Resource Website
100+ mentions
Circlator (RRID:SCR_016058) software application, data processing software, software toolkit, image analysis software, software resource, alignment software Software that automates assembly circularization and produces accurate linear representations of circular sequences. It is used for assembling of DNA sequence data of complete bacterial and small eukaryotic genomes. assembly, sequence, genome, DNA, circularization, accurate, bacteria, erukaryote, tool is listed by: Debian
is listed by: OMICtools
Wellcome Trust grant 098051 PMID:26714481
DOI:10.1186/s13059-015-0849-0
Free, Available for download OMICS_09488 https://github.com/sanger-pathogens/circlator
https://sources.debian.org/src/circlator/
SCR_016058 2026-02-16 09:48:56 321
Clearcut
 
Resource Report
Resource Website
10+ mentions
Clearcut (RRID:SCR_016059) software application, data processing software, data visualization software, software resource, standalone software THIS RESOURCE IS NO LONGER IN SERVICE. Documented on February 28,2023.Software as a stand-alone reference implementation for the Relaxed Neighbor Joining (RNJ) algorithm. Used in distance-based phylogenetic tree reconstruction method to process large sequence datasets., THIS RESOURCE IS NO LONGER IN SERVICE. Documented on September 16,2025. rnj, phylogenetic, tree, construction, neighbor, joining, distance, method, reference, standalone, implemetation, relaxed, algorithm, phylogenetic, tree, reconstruction, sequence is listed by: Debian
is listed by: OMICtools
is related to: University of Idaho; Idaho; USA
NIH P20 RR16448;
INBRE Program of the National Center for Research Resources ;
NSF EPS 00809035;
NIH P20 RR16454
PMID:16752216
DOI:10.1007/s00239-005-0176-2
THIS RESOURCE IS NO LONGER IN SERVICE OMICS_15083 https://github.com/ibest/clearcut
https://sources.debian.org/src/clearcut/
SCR_016059 2026-02-16 09:48:56 26
MGnify
 
Resource Report
Resource Website
50+ mentions
MGnify (RRID:SCR_016429) data repository, storage service resource, portal, service resource, data or information resource Portal for the analysis and exploration of metagenomic, metatranscriptomic, amplicon and assembly data. Provides functional and taxonomic analyses of user-submitted sequences, as well as analysis of publicly available metagenomic datasets held within the European Nucleotide Archive (ENA).Microbiome analysis resource in 2020. analysis, exploration, metagenomic, metatranscriptomic, amplicon, assembly, data, sequence, ENA, microbial, population, environment, bio.tools is recommended by: NIDDK Information Network (dkNET)
is recommended by: NIDDK - National Institute of Diabetes and Digestive and Kidney Diseases
is listed by: Debian
is listed by: bio.tools
is related to: NIDDK Information Network (dkNET)
the Biotechnology and Biological Sciences Research Council (BBSRC) BBM0117551;
the Biotechnology and Biological Sciences Research Council (BBSRC) BBN0183541;
the European Commission within the Research Infrastructures programme of Horizon 2020 676559;
InnovateUK 102513;
Research Councils UK (RCUK) ;
EMBL ;
the Biotechnology and Biological Sciences Research Council BBI02612X1;
the Biotechnology and Biological Sciences Research Council BBM0117551;
EU Seventh Framework Programme for Research MICROB3
PMID:31696235 Free, Freely available, Training online available r3d100011192, biotools:MGnify https://bio.tools/MGnify
https://doi.org/10.17616/R34W68
SCR_016429 , MGnify, EBI Metagenomics 2026-02-16 09:49:01 51
ASTRA
 
Resource Report
Resource Website
50+ mentions
ASTRA (RRID:SCR_016255) software application, data processing software, software toolkit, data analysis software, software resource Software for the characterization of macromolecules and nanoparticles via multi-angle and dynamic light scattering. It simplifies MALS and DLS analysis for assessment of molar mass, size, conformation, conjugation, and other essential physical parameters. macromolecule, nanoparticle, light, scattering, mals, dls, hplc, sequence, processing SCR_016255 ASTRA6, Wyatt Technologies ASTRA, ASTRA Software 2026-02-16 09:48:59 88
Entrez
 
Resource Report
Resource Website
10+ mentions
Entrez (RRID:SCR_016640) web service, data access protocol, software resource, portal, data or information resource Web portal for global query cross database search and retrieval system that provides access to all databases simultaneously with a single query string and user interface. Retrieves nucleotide and protein sequence data, gene centered and genomic mapping information, 3D structures, and references. Covers databases including protein sequence data from PIR-International, PRF, Swiss-Prot, and PDB and nucleotide sequence data from GenBank that includes information from EMBL and DDBJ. global, query, cross, database, search, retrival, system, database, nucleotide, protein, sequence, data, genomic, mapping, structure, reference is affiliated with: PubChem BioAssay
is related to: National Library of Medicine
has parent organization: NCBI
works with: Batch Entrez
works with: Biotite
Free, Freely available SCR_016640 2026-02-16 09:49:04 15
MOLE-BLAST
 
Resource Report
Resource Website
1+ mentions
MOLE-BLAST (RRID:SCR_016644) moleblast, Mole Blast, MOLE BLAST software application, data processing software, web service, sequence analysis software, data analysis software, data access protocol, software resource Software tool that helps taxonomists find closest database neighbors of submitted query sequences by generating a phylogenetic tree from BLAST results. taxonomist, find, close, database, submitted, query, sequence, generate, phylogenetic, tree, nucleotide works with: NCBI BLAST Free, Freely available SCR_016644 2026-02-16 09:49:04 1
VecScreen
 
Resource Report
Resource Website
10+ mentions
VecScreen (RRID:SCR_016577) software application, data processing software, sequence analysis software, data analysis software, software resource, service resource Software tool to screen a nucleic acid sequence for vector contamination. Detects foreign DNAs such as vector, linker, adapter, and primer regions involved in nucleotide sequences by using blast search against vector sequence database. The main unit of this tool is vecscreen program obtainable from NCBI. screen, sequence, nucleic acid, segment, vector, contamination is listed by: OMICtools Free, Available for download, Freely available https://www.ddbj.nig.ac.jp/vecscreen-help-e.html SCR_016577 2026-02-16 09:49:03 48

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