Tools   Select Another Resource Report Type

http://cgap.nci.nih.gov/

Project to determine the gene expression profiles of normal, precancer, and cancer cells, whose generated resources are available to the cancer community. Interconnected modules provide access to all CGAP data, bioinformatic analysis tools, and biological resources allowing the user to find in silico answers to biological questions in a fraction of the time it once took in the laboratory. * Genes * Tissues * Pathways * RNAi * Chromosomes * SAGE Genie * Tools

Proper citation: Cancer Genome Anatomy Project (RRID:SCR_003072) Copy   

•   Source: SciCrunch Registry

https://github.com/jstjohn/SimSeq

An illumina paired-end and mate-pair short read simulator. This project attempts to model as many of the quirks that exist in Illumina data as possible. Some of these quirks include the potential for chimeric reads, and non-biotinylated fragment pull down in mate-pair libraries .

Proper citation: SimSeq (RRID:SCR_006947) Copy   

•   Source: SciCrunch Registry

https://bioconductor.org/packages/release/bioc/html/oligo.html

Software package to analyze oligonucleotide arrays (expression/SNP/tiling/exon) at probe-level. It currently supports Affymetrix (CEL files) and NimbleGen arrays (XYS files).

Proper citation: oligo (RRID:SCR_015729) Copy   

•   Source: SciCrunch Registry

http://abacus.gene.ucl.ac.uk/software/indelible/

Software that generates nucleotide, amino acid and codon sequence data by simulating insertions and deletions (indels) as well as substitutions. It is used for biological sequence simulation of multi-partitioned nucleotide, amino-acid, or codon data sets through the processes of insertion, deletion, and substitution in continuous time.

Proper citation: Indelible (RRID:SCR_016163) Copy   

•   Source: SciCrunch Registry

https://mia.sourceforge.net/

Software toolkit for gray scale medical image analysis. Provides combination of command line tools, plug-ins, and libraries that make it possible to run image processing tasks interactively in command shell and prototype algorithms as shell scripts. MIA is build around a plug-in structure that makes it easy to add functionality without compromising the original code base, and it makes use of wide variety of external libraries that provide additional functionality.

Proper citation: MIA (RRID:SCR_024081) Copy   

•   Source: SciCrunch Registry

http://libroadrunner.org/

Simulation engine for systems and synthetic biology to be used with other software applications. It retains the original functionality of RoadRunner but has changes in performance, back-end design, event handling, new C++ API, and stochastic simulation support.

Proper citation: libRoadRunner (RRID:SCR_014763) Copy   

•   Source: SciCrunch Registry

http://rast.nmpdr.org

A SEED-quality automated service that annotates complete or nearly complete bacterial and archaeal genomes across the entire phylogenetic tree. RAST can also be used to analyze draft genomes.

Proper citation: RAST Server (RRID:SCR_014606) Copy   

•   Source: SciCrunch Registry

http://code.google.com/p/pbsim/

Software that simulates PacBio reads by using either a model-based or sampling-based simulation.

Proper citation: PBSIM (RRID:SCR_002512) Copy   

•   Source: SciCrunch Registry

https://github.com/bcgsc/NanoSim

Software tool as Nanopore sequence read simulator based on statistical characterization. Oxford Nanopore Technology sequence simulator written in Python and R. Benefits development of scalable next generation sequencing technologies for long nanopore reads, including genome assembly, mutation detection, and metagenomic analysis software.

Proper citation: NanoSim (RRID:SCR_018243) Copy   

•   Source: SciCrunch Registry

https://github.com/dmnfarrell/epitopepredict

Open source software tool as programmatic framework and command line tool designed to aid process of MHC binding prediction. Provides access to multiple binding prediction algorithms under single interface and scales for whole genomes using multiple target MHC alleles.Software should be run on Linux operating system. Ubuntu is recommended but most major distributions will be fine. Windows is not supported.

Proper citation: epitopepredict (RRID:SCR_019221) Copy   

•   Source: SciCrunch Registry

https://bioconductor.org/packages/variancePartition/

Software R package to quantify and interpret divers of variation in multilevel gene expression experiments.Provides statistical and visualization framework for studying drivers of variation in RNA-seq datasets in many types of high throughput genomic assays including RNA-seq gene-, exon- and isoform-level quantification, splicing efficiency, protein quantification, metabolite quantification, metagenomic assays, methylation arrays and epigenomic sequencing assays.

Proper citation: variancePartition (RRID:SCR_019204) Copy   

•   Source: SciCrunch Registry

http://metagenomics.iiserb.ac.in/mp3/

Software tool for prediction of pathogenic proteins in genomic and metagenomic data. Used for identification of partial pathogenic proteins predicted from short (100-150 bp) metagenomic reads and also performs on complete protein sequences., THIS RESOURCE IS NO LONGER IN SERVICE. Documented on September 16,2025.

Proper citation: MP3 tool (RRID:SCR_019282) Copy   

•   Source: SciCrunch Registry

https://github.com/fhcrc/seqmagick/

Software application to expose file format conversion in BioPython in convenient way. Imagemagick like frontend to Biopython SeqIO.

Proper citation: seqmagick (RRID:SCR_024331) Copy   

•   Source: SciCrunch Registry

https://github.com/WorkflowConversion/CTDopts

Software gives your command-line tools a CTD-compatible interface. Module for enabling tools with CTD reading/writing, argument parsing, validating and manipulating capabilities.

Proper citation: CTDopts (RRID:SCR_023997) Copy   

•   Source: SciCrunch Registry

https://github.com/jkbonfield/htscodecs/

Software repository implements the custom CRAM codecs used for "EXTERNAL" block types.Custom compression for CRAM custom algorithm written to compress the BAM file format for DNA sequencing data.

Proper citation: Htscodecs (RRID:SCR_024034) Copy   

•   Source: SciCrunch Registry

https://github.com/conda/conda-package-handling

Software to create and extract conda packages of various formats.

Proper citation: conda-package-handling (RRID:SCR_023991) Copy   

•   Source: SciCrunch Registry

http://www.cbcb.umd.edu/software/ELPH/index.shtml

Software tool as general purpose Gibbs sampler for finding motifs in set of DNA or protein sequences.Takes as input a set containing sequences, and searches through them for the most common motif, assuming that each sequence contains one copy of the motif. Used to find patterns such as ribosome binding sites (RBSs) and exon splicing enhancers (ESEs).

Proper citation: ELPH (RRID:SCR_024011) Copy   

•   Source: SciCrunch Registry

https://github.com/PacificBiosciences/unanimity

Software to generate highly accurate single molecule consensus reads.

Proper citation: CCS (RRID:SCR_024379) Copy   

•   Source: SciCrunch Registry

https://github.com/cancerit/alleleCount

Software package to prevent code duplication. Support code for NGS copy number algorithms. Generates count of coverage of each allele ACGT at that location given any filter settings.

Proper citation: alleleCount (RRID:SCR_023961) Copy   

•   Source: SciCrunch Registry

https://github.com/mateidavid/fast5

Software C++ library for accessing Oxford Nanopore Technologies sequencing data.

Proper citation: Fast5 Library (RRID:SCR_024023) Copy   

•   Source: SciCrunch Registry