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SciCrunch Registry is a curated repository of scientific resources, with a focus on biomedical resources, including tools, databases, and core facilities - visit SciCrunch to register your resource.
Genes to Cognition (G2C) Online is about modern neuroscience. It focuses on cognitive disorders, cognitive processes, and research approaches. Use the dynamic network maps to explore our library of 750+ unique items. Or, use the linear Selected Items menu on top of each map to tour selected content. Read the G2C blog, use simple mapper, or the 3-D brain, an interactive model of the brain. Disorders included in this site: ADHD, Alzheimer's Disease, Autism, Bipolar Disorder, Depression, Schizophrenia Cognitive Processes include: Attention, Language, Learning and Memory, Perception, and Thinking Research Approaches include: Bioinformatics, Ethics, Gene Finding, Model systems, Neuroimaging, Psychology. Navigation: Interact with the dynamic Networks Maps to explore the full catalog of content. Roll-over a node on the map for a preview and click to open the content. Move on to other content by returning to the network map. Each node you visit on the map gets flagged. Follow the Selected Items Subway Line for an overview of a topic. Roll-over a subway node for a preview and click to open the content. Other Features: Most content items include links to Related Items, which allow you to explore further. The Glossary includes over 300 neuroscience keywords. Search for content using keywords or id number. Select a preferred network map to view the content in context. Open/close the History at the lower left to view visited content. Your history is stored until you clear it. Simple Mapper - We developed Simple Mapper to power this web site on the brain. Now, you can use it to organize what comes out of yours! With Simple Mapper create and save concept maps, network diagrams, or flowcharts for personal use or to share with others. 3-D Brain - The G2C Brain is an interactive 3-D model of the brain, with 29 structures that can be rotated in three-dimensional space. Each structure has information on brain disorders, brain damage, case studies, and links to modern neuroscience research. Ideal for students, researchers, and educators in psychology and biology. Also available for download: 3D Brain App for iPhone and iPod Touch!
Proper citation: Genes to Cognition Online (RRID:SCR_002746) Copy
http://www.cephalopod.org/DBMR.cfm
THIS RESOURCE IS NO LONGER IN SERVICE, documented on July 17, 2013. The center serves the biomedical research community's increased needs for alternative invertebrate models by maintaining a consistent year-round supply of live cephalopod mollusks. These animals are suitable for a wide range of physiological and molecular biological investigations. Investigations are being conducted in the area of life history related to improved animal husbandry. Further studies focus on improving culture system design through development of computer automation and innovative water filtration technology. Current biomedical research on cephalopods includes neurophysiology of the giant axon; anatomy and neurophysiology of the equilibrium receptor organ as a comparative model of the vestibular system of invertebrates; chemoreception, basic nutrition, and protein metabolism; cellular receptor function; and brain, behavior, and learning. Services Provided: The center has built a computer-automated, environmentally controlled, recirculating seawater laboratory for the purpose of culturing cephalopods. The tank systems can be used to conduct a variety of experiments never before possible with cephalopods. Visiting researchers have access to dedicated facilities, including wet and dry laboratory space, office space, computer support and accommodations, as well as priority access to all available live animal resources. Off-site investigators can have live animals, dissected animal tissues/body fluids from all life stages, and a variety of molecular reagents (gene libraries and clones) delivered year-round. Staff expertise and an extensive literature library are available. All life stages of the squid (Sepioteuthis lessoniana) and the common cuttlefish (Sepia officinalis) are available year-round from laboratory culture populations. The sepiolid squid (Euprymna scolopes) can also be cultured on request. The squid Lolliguncula brevis is available year-round from local waters; the squids Loligo opalescens, L. pealeii, and L. plei can be obtained seasonally on request. The chambered nautilus, Nautilus pompilius, and Octopus bimaculoides are available on request. Animal costs vary by species and size. Any tissue or body fluid from these animals can also be provided. Fees for special services are negotiated on a case-by-case basis.
Proper citation: National Resource Center for Cephalopods (RRID:SCR_002864) Copy
http://www.ualberta.ca/~aprochaz/Index.html
The lab of Arthur Prochazka, whose research focuses on routing electrical current from surface electrodes to deep-lying nerves using implanted conductors. His research mostly focuses on muscle physiology. Current fields of research: * Stimulus Router System: A new family of implanted neuroprostheses. It comprises an implanted lead that picks up some of the current delivered through the skin by a surface stimulator and delivers it to a target nerve via a nerve cuff. The SRS has the advantages of an implanted stimulator: selectivity, reproducibility and convenience, at a fraction of the cost * Bionic Glove: Hand opening and closing stimulator for C5-C6 tetraplegic people. It is based on Functional Electrical Stimulation (FES). * In-home Telerehabilitation: Providing exercise sessions over the internet. * Interactive Receptor Model: An online model explaining muscle spindles and tendon organs. * Spinal Motoneuron Activity During Gait * Robocats: Mathematical models for locomotion. * Rigidity Analyzer: A better means of assessing rigidity. * General Research: Fundamental questions in our field of neurophysiology. * Spinal Cord Microstimulation: Restoring bladder function after spinal cord injury.
Proper citation: Arthur Prochazka Laboratory, University of Alberta (RRID:SCR_002747) Copy
http://rana.lbl.gov/drosophila
A single source for sequences, assemblies, annotations and analyses of the genomes of members of the fruitfly genus Drosophlia. It is meant as resource for Drosophilists and other researchers interested in comparative analysis of these species and their genomes. There are pages for each species, as well as pages for different types of multi-species resources (e.g. alignments). If you have a public resource that will help this project, please consider making it available through this page by emailing multiple_at_fruitfly.org.
Proper citation: Assembly/Alignment/Annotation of 12 Related Drosophila Species (RRID:SCR_002921) Copy
http://celeganskoconsortium.omrf.org
THIS RESOURCE IS NO LONGER IN SERVCE, documented September 2, 2016. The mission of the C. elegans Gene Knockout Consortium is to facilitate genetic research of this important model system through the production of deletion alleles at specified gene targets. We choose targets based on investigator requests. Strains produced by the consortium are freely available with no restrictions to any investigator. At one time, our capacity dictated that we restrict requests to five per lab. This restriction no longer holds. Investigators are encouraged especially to register requests for functionally related groups of genes. Consortium strains are distributed by the C. elegans Genetic Center (CGC). In most cases, when you use the Consortium web site to request an existing allele, your request is forwarded automatically to the CGC. However, if you indicate that an existing allele is not satisfactory for your research, (for whatever reason), you may request that we generate another allele for the same target. Any information generated by the Consortium is entered into the official C. elegans data repository, WormBase.
Proper citation: C. elegans Gene Knockout Consortium (RRID:SCR_003000) Copy
Portal to support researchers and practitioners searching for information related to alcohol research including links to a number of databases, journals, and Web sites focused on alcohol research and related topics. Also included is a link to the archived ETOH database, the premier Alcohol and Alcohol Problems Science Database, which contains over 130,000 records and covers the period from 1972 through 2003. Included in ETOH are abstracts and bibliographic references to journal articles, books, dissertation abstracts, conference papers and proceedings, reports and studies, and chapters in edited works. ETOH's scope reflects the multidisciplinary nature of the alcohol research field. The range of subject areas contained in ETOH includes: medicine, biochemistry, psychology, psychiatry, epidemiology, sociology, anthropology, treatment, prevention, education, accidents and safety, legislation, criminal justice, public policy, and health services research. The ETOH database is indexed with vocabulary from the Alcohol and Other Drug Thesaurus: A Guide to Concepts and Terminology in Substance Abuse and Addiction (AOD Thesaurus), Third Edition. More than 5,000 terms in the AOD Thesaurus are used as ETOH descriptors. The Databases/Resources section includes databases and resources for alcohol researchers and practitioners. It includes an introduction to the National Library of Medicine's PubMed and some sample searches on alcohol to run in the PubMed database; descriptions of and links to the various databases of the National Clearinghouse for Alcohol and Drug Information (NCADI); a selection of alcohol and other drug databases with their descriptions and links; links to peer-reviewed journals most often used by alcohol researchers; and links to a selection of Web sites pertinent to the substance abuse field.
Proper citation: Alcohol and Alcohol Problems Science Database (RRID:SCR_003768) Copy
A web portal that aggregates information and educational materials about the brain and brain diseases. Resources such as videos, key brain concepts, and hands-on activities may be used and shared with the public.
Proper citation: brainfacts.org (RRID:SCR_003514) Copy
http://clinicalinformatics.stanford.edu/projects/cdw.html
Research and development project at Stanford University to create a standards-based informatics platform supporting clinical and translational research. STRIDE consists of three integrated components: a clinical data warehouse, based on the HL7 Reference Information Model (RIM), containing clinical information on over 1.6 million pediatric and adult patients cared for at Stanford University Medical Center since 1995; an application development framework for building research data management applications on the STRIDE platform and a biospecimen data management system. STRIDE's semantic model uses standardized terminologies, such as SNOMED, RxNorm, ICD and CPT, to represent important biomedical concepts and their relationships. STRIDE receives clinical data for research use via HL7 feeds from both SUMC hospitals: Lucile Packard Children's Hospital and Stanford Hospital and Clinics. This clinical data is used to support a wide variety of translational research services including: * Anonymized Patient Research Cohort Discovery * Electronic Chart Review for Research * IRB-Approved Clinical Data Extraction * Biospecimen Data Management * Multimedia Research * Data Management and Research Registries STRIDE is a highly secure environment utilizing encryption, fine-grained access control, robust auditing and detailed data segregation. Additionally, STRIDE has a robust access control framework with well-defined access granting authorities and access control groups. Consequently STRIDE meets or exceeds the requirements of the HIPAA Privacy and Security regulations. Privacy protection is further enhanced by requiring IRB approval for all research projects using STRIDE clinical data. From a technology and standards perspective, STRIDE is hosted on the Oracle 11g database platform. STRIDE application software provides access to the web services of a three-tier infrastructures using SSL encryption with strong authentication. These programs are cross-platform, self-updating thick-client applications that provides a rich user interface for data entry, retrieval and review as well as image manipulation and annotation. STRIDE makes extensive use of XML technologies for representation of structured meta data, distributed systems technologies using JSON for secure remote communication between client and server, and Swing graphical interface components providing a rich widget-set as well as advanced imaging and graphing capabilities. Users of the STRIDE Research Desktop Client can perform rapid data entry into structured fields, compose complex queries, and interact securely with clinical, research and imaging data.
Proper citation: Stanford Translational Research Integrated Database Environment and Clinical Data Warehouse (RRID:SCR_003453) Copy
http://www.asia-spinalinjury.org
This website provides information about the American Spinal Injury Association. The mission of ASIA is to: (a) to promote and establish standards of excellence for all aspects of health care of individuals with spinal cord injury from onset throughout life. (b) to educate members, other healthcare professionals, patients and their families as well as the public on all aspects of spinal cord injury and its consequences in order to prevent injury, improve care, increase availability of services and maximize the injured individual''s potential for full participation in all areas of community life. (c) to foster research which aims at preventing spinal cord injury, improving care, reducing consequent disability, and finding a cure for both acute and chronic SCI. (d) to facilitate communication between members and other physicians, allied health care professionals, researchers and consumers.
Proper citation: American Spinal Injury Association (RRID:SCR_012977) Copy
http://cirrie.buffalo.edu/search/index.php
The CIRRIE Database of International Rehabilitation Research currently contains almost 90,000 citations of international rehabilitation research published between 1990 and the present. The CIRRIE Database collects citations from all areas of rehabilitation and compiles them into one central source. In addition to indexing from mainstream journals and internet sites, CIRRIE also includes citations to resources not readily available to U.S. researchers. Over 5000 journals are represented in the Database and abstracts are available for most citations. A list of journals is now available. There are almost 90,000 citations currently indexed with citations added monthly. The database includes citations from 1990 to the present. It was created to facilitate the sharing of information and expertise in rehabilitation and disability research between the U.S. and other countries.
Proper citation: Database of International Rehabilitation Research (RRID:SCR_013008) Copy
http://www.brain.northwestern.edu/research/for-researchers/index.html
Tissue bank for collecting, cataloging and storing postmortem brain tissue samples from subjects with and without neurological disorders. Specimens are available for research on cognitive impairment, Alzheimer's, dementia and other disorders along with clinical data such as demographic information, health and family history and neuropsychological test scores. The bank provides services to distribute postmortem brain tissue and other samples to investigators for use in research that will provide qualitative and quantitative diagnostic information to physicians, families, and researchers.
Proper citation: Northwestern CNADC Tissue Bank / Neuropathology Core (RRID:SCR_013178) Copy
http://www.siumed.edu/alz/index.html
Resource center that provides assistance for patients and families affected by Alzheimer's disease and related conditions. The Center provides patient care through the Memory and Aging Clinic as well as through research, education and service to the community. Additionally the Center provides training in dementia care, maintains centralized data collection, and sponsors programs of research that qualify for federal financial participation.
Proper citation: SIU Center for Alzheimer's Disease and Related Disorders (RRID:SCR_013199) Copy
A research forum portal for ALS-related resources targeted specifically towards academic and industry-based researchers. The aim of the ALS Forum is to identify existing research resources and build new tools to help veteran researchers accelerate their work and to help those new to the ALS field quickly get up to speed. It currently consists of content developed through a partnership with the Alzforum and filtered for its relevance to ALS, as well as links to ALS review articles, and a dynamic listing of current drug development efforts relevant to ALS.
Proper citation: ALS Forum (RRID:SCR_007160) Copy
http://hearingimpairment.jax.org/screening.html
The fairly common occurrence of hearing-loss or deafness in both humans and mice, and the anatomical and functional similarities of their inner ears, attest to the potential of mice as models to study hereditary hearing loss. Hundreds of standard inbred, recombinant inbred, and congenic strains are maintained at The Jackson Laboratory, as well as hundreds of inbred strains with spontaneous or induced mutations. To assess hearing impairment in inbred and mutant strains of mice we measure auditory-evoked brainstem response (ABR) thresholds.
Proper citation: The Jackson Laboratory Hearing Research Program (RRID:SCR_007196) Copy
http://www.nia.nih.gov/research/dn
A funding resource that supports the research and training for understanding the structure and function of the aging nervous system, with an emphasis on studies involving Alzheimer's disease and age-related dementia. There is an emphasis on brain-behavior relationships. This program is composed of three branches: Neurobiology, Neuropsychology, and Dementias of Aging. The overall aim of this program is to understand the aging nervous system to minimize mental decline and improve the lives of older patients. This resource also includes links to sites for Alzheimer's disease (AD) studies that include: specimen repositories, genetic materials, bio-markers, data, policies on NIA and AD genetics sharing plans, and additional aging or other AD related links.
Proper citation: National Institute on Aging, Division of Neuroscience (RRID:SCR_008257) Copy
http://dpcpsi.nih.gov/orip/cm/chimpanzee_management_program.aspx
Center that supports long-term, cost-effective housing and maintenance at NCRR-supported facilities for chimpanzees. NCRR provides programmatic oversight of the facilities and ensures they comply with the Animal Welfare Act, and policies concerning laboratory animal care and use.
Proper citation: Chimpanzee Management Program (RRID:SCR_008377) Copy
A portal to educate, engage and create an online community. The Fisher Center for Alzheimer''s Research Foundation, founded in 1995, was created in answer to the recommendations of three U.S. Senate commissioned symposia held in the 1990s by the National Institutes of Health (NIH) to gather information on the cause, care and cure of Alzheimer''s disease. The Fisher Center was created following this design. The funding initiatives of the Foundation are appropriated accordingly to the three areas cited by the NIH task force cause, care and cure. The primary resources of the Foundation are directed toward scientific research into the cause and hopefully the cure of Alzheimer''s disease. To this end, the Foundation under the direction of its founder, Zachary Fisher, and in collaboration with David Rockefeller, constructed the Fisher Center for Alzheimer''s Disease Research at The Rockefeller University, headed by 2000 Nobel Prize winner, Paul Greengard, Ph.D. The 10,000 square foot laboratory is the most advanced facility of its kind in the country equipped with the latest in equipment necessary to undertake an interdisciplinary assault on this disease. The Fisher Center also has collaborative programs at the University of Genoa and supports the work of well over 60 scientists and researchers across the United States and in 17 foreign countries. The Foundation also funds projects for the care of people with Alzheimer''s disease and their caregivers. The Fisher Alzheimer''s Disease Education and Resources Program at the New York University School of Medicine was established under the direction of Barry Reisberg, M.D., internationally known expert in the care of Alzheimer''s patients. The Foundations Alzheimer''s Information Program was created in 2001 to answer the primary need of caregivers for comprehensive, easily accessible information. Our goals are to: Understand the Cause of Alzheimer''s To find a Cure for this devastating disease Improve the Care of people living with the disease to enhance their quality of life and that of their caregivers and families About Our Research Beating Back Beta Amyloid Improving the Quality of Life for Alzheimers Patients Reversing Nerve Cell Damage Using Hormones to Slow the Progress of Disease Curing Early-Onset Alzheimers The Science of Caregiving Scientific Studies
Proper citation: Fisher Center For Alzheimers Research Foundation: ALZinfo.org (RRID:SCR_008255) Copy
http://www.ncrr.nih.gov/comparative_medicine/resource_directory/primates.asp#alamo
THIS RESOURCE IS NO LONGER IN SERVICE, documented on July 17, 2013. It houses chimpanzees that have been used in biomedical research, but no active, invasive research is conducted on the site. The APF provides for the long-term care and husbandry of chimpanzees that have been used in biomedical research. Charles River Laboratories Inc. operates the facility under contract with the National Institutes of Health. To be used in continuing virological research, the animals must be transferred to active chimpanzee research settings. All chimpanzees at the APF have been exposed to various microorganisms, such as hepatitis C virus and HIV. For this reason, they may be candidates for studies related to these diseases. The National Center for Research Resources (NCRR) may remove infected animals from the APF to other accredited chimpanzee facilities for research purposes. Investigators interested in the chimpanzees at the APF should contact Dr. Harold Watson in NCRR''s Division of Comparative Medicine to discuss research requirements.
Proper citation: Alamogordo Primate Facility (RRID:SCR_008376) Copy
THIS RESOURCE IS NO LONGER IN SERVICE, documented August 23, 2016. Vision Science is a large discipline at the ANU that is found in several teaching and research faculties and several large research institutes. About 85 research staff participate in all forms of vision science from machine vision, to neurophysiology, behaviour and cognition. The scale of analysis ranges from molecular to systems approaches and covers insect, vertebrate and human visual systems. Topics such as disease and development of the human visual system are also covered. CVS works to connect and sustain the component parts of the ANU vision science community.
Proper citation: Centre for Visual Sciences (RRID:SCR_008324) Copy
http://depts.washington.edu/adai/
The Alcohol and Drug Abuse Institute is a multidisciplinary research center at the University of Washington. Its mission is to support and facilitate research and research dissemination in the field of alcohol and drug abuse. Recognizing the need to address the enormous problems caused by alcohol and drug abuse, the University of Washington established the Alcohol and Drug Abuse Institute in October of 1973 as an interdisciplinary research center in the Warren G. Magnuson Health Sciences Center. From its beginning, the mission of the Institute has been to conduct and support substance abuse research at the University of Washington, and disseminate research findings in substance abuse. The activities of the Institute may be described under three general headings: Intramural research by ADAI Research Scientists supported through federal, state, and other grants and contracts; Stimulation and support of research by ADAI Research Affiliates and faculty in departments throughout the University through a Small Grants Program. Since 1973, ADAI has awarded almost three million dollars to researchers in 40 University departments, for approximately 300 projects. Many of those funded projects led to outside funding for expanded research. Dissemination of research findings through its Library and Information Service, publications and presentations by ADAI scientists, web page, listservs, newsletters, and symposia. The Institute receives financial support from the State of Washington under state Initiative 171, which mandates that a portion of fees collected for state liquor licenses be allocated to the two state research universities for research on alcohol and drug abuse, and dissemination of research information. The University of Washington provides additional funding. Research studies are funded primarily through grants and contracts awarded by federal and state agencies and private foundations. The Alcohol and Drug Abuse Institute serves as a focal point for alcohol and drug abuse research at the University of Washington and in the region, benefiting the citizens of Washington State by expanding our knowledge and making information available to health and social service professionals and policy makers. The Institute''s multidisciplinary staff of clinical and social psychologists, sociologists, epidemiologists, public health experts, educators, and librarians plays a key role in working to understand and reduce the harm caused by alcohol and drug abuse. Dennis M. Donovan, Ph.D. has been the Director of the Alcohol and Drug Abuse Institute since 1993. Dr. Donovan is a Professor in the Department of Psychiatry and Behavioral Sciences and an Adjunct Professor in the Department of Psychology.
Proper citation: Alcohol and Drug Abuse Institute, University of Washington (RRID:SCR_008283) Copy
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