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SciCrunch Registry is a curated repository of scientific resources, with a focus on biomedical resources, including tools, databases, and core facilities - visit SciCrunch to register your resource.
https://www.lsuhs.edu/centers/cardiovascular-diseases-and-sciences/cobre/cobre-core-facilities
Facility includes Analytic Redox Biology and Molecular Signaling Sub-Cores. Provided services include measurements of reactive oxygen species, reactive nitrogen species, reactive sulfide species, protein, peptides, metabolites, and lipids in cell culture and tissue samples. High-performance liquid chromatography systems, coupled with UV-vis and fluorescence detectors to quantify cellular and mitochondrial superoxide production, hydrogen sulfide pools (free sulfide, sulfide bound to transitional metals, and sulfane sulfur), and thiols (glutathione, GSH/GSSG, cysteine, cystine, homocysteine, persulfides, and glutathionylation).Instruments include Sievers NO Analyzer (NOA 280i, GE), Agilent 8890 GC and 8335 sulfur chemiluminescence detector ,Thermo Scientific Orbitrap Exploris 480 and SCIEX Triple Quad 7500 mass spectrometer. Molecular Signaling Sub-Core offers services for molecular cloning and site-directed mutagenesis, design and production of vectors for CRISPR/Cas9 modification of vascular cells, services for endothelial, smooth muscle, and cardiac myocyte cell isolation, for generation of vascular cell lines, and for lentivirus production for transient or stable modification of cardiovascular cells, access to equipment and expertise for studying cellular effects of hypoxia/reoxygenation injury (Coy Hypoxic Chamber, CLARIOstar Spectrofluorometer), for automated capillary Western blot analysis (ProteinSimple Jess Simple Western), and for high-resolution fluo-respirometry to study mitochondrial function (Oroboros O2k modular system).
Proper citation: Louisiana State University in Shreveport Redox Molecular Signaling Core Facility (RRID:SCR_024778) Copy
Core supports data analysis, network modeling, and data science research. Provides training and education opportunities.
Proper citation: Louisiana State University in Shreveport CAIPP Bioinformatics and Modeling Core Facility (RRID:SCR_024779) Copy
http://mayoresearch.mayo.edu/center-for-individualized-medicine/medical-genome-facility.cfm
Medical Genome Facility includes Cytogenetics Core, Genome Analysis Core and Proteomics Core. Available services include Sanger DNA sequencing, genotyping, gene expression and cytogenetic analysis, biospecimens accessioning and processing, tissue and cell molecular analysis, RNA interference, and oligonucleotide synthesis. Provides Illumina HiSeq2000 platforms and Pacific Biosciences RS single molecule real-time sequencer.Offers applied research services for development of innovative, personalized tests and treatments, especially with regard to biomarkers.
Proper citation: Mayo Clinic Medical Genome Core Facility (RRID:SCR_024632) Copy
https://snyder.ucalgary.ca/labs/live-cell-imaging/LCIoverview
Offers advanced imaging technology, as well as training and support personalized to their imaging goals and experience. Provides Technology access and training; Assisted imaging and coaching at every step of the imaging workflow, from sample preparation to data analysis; Pilot experiments and feasibility testing; Developing custom image analysis pipelines; Image analysis consultation and training; Developing and testing new instruments and devices; Full scientific and technological collaborations and partnerships; Offsite coaching, assistance and consulting ; Collaborative projects in academic, health and allied industrial sectors;
Proper citation: University of Calgary Live Cell Imaging Laboratory Core Facility (RRID:SCR_024748) Copy
https://www.medschool.umaryland.edu/cibr/core/tgl/
Core provides range of genomics technologies to support basic, translational, and clinical research.Services support basic research. Clinical assays offered are similar to those offered to support basic research, except that these assays are validated under CLIA, enabling them to be used in clinical decision making process in research protocols and for routine patient care.
Proper citation: University of Maryland School of Medicine Translational Genomics Laboratory Core Facility (RRID:SCR_024749) Copy
https://www.innovation.fsu.edu/
Hosts makerspaces, labs, and promotes design based frameworks toward iteration and innovation. Acts as open intersection of university departmental collaboration and provides access to low barrier prototyping tools. Supports FSU student, staff, and faculty research initiatives.
Proper citation: Florida State University Innovation Hub Core Facility (RRID:SCR_024482) Copy
https://azclincore.arizona.edu/
Core is CLIA certified/CAP accredited laboratory specializing in high complexity genetic and serological clinical testing and research. Provides inpatient and outpatient diagnostic testing services as well as support for clinical trial and clinical research activities for physicians, researchers and industry clients. The AZClinCore has aided in development of novel genetic testing and clinical trial protocols as well as providing evaluations for new technology and testing platforms. Supports end-to-end clinical testing as well as reference lab services.
Proper citation: University of Arizona Molecular Clinical Core Facility (RRID:SCR_024479) Copy
https://www.iqm.unicamp.br/en/research/limicro/
Core offers services in advancing scientific research in the field of chemistry. Provides Scanning Electron Microscopy (SEM), Atomic Force Microscopy (AFM), Confocal Laser Scanning Microscopy (CLSM), and Optical Microscopy. Offers sample preparation techniques, including ultramicrotome, ultracryomicrotome, and sputter coating,training and technical support.
Proper citation: State University of Campinas Institute of Chemistry Microscopy Core Facility (RRID:SCR_024633) Copy
https://www.uml.edu/research/crf/ourlabs/therm-mech-prop-lab.aspx
Core houses thermal analysis suite. Researchers are able to investigate behavior of material under stress and temperature change. Service level work and technical expertise are provided.
Proper citation: University of Massachusetts Lowell Thermal and Mechanical Properties Lab Core Facility (RRID:SCR_024980) Copy
https://www.uml.edu/research/crf/ourlabs/next-gen-sequencing-lab.aspx
Core provides Next-Generation DNA and RNA sequencing services and technical expertise including NGS library prep, DNA and RNA quality assessment, Fluorometric quantification of DNA/RNA/Protein, DNA and RNA isolation, PCR/qPCR, Qubit fluorometry, gene expression and drug development studies. Consultative services are available.
Proper citation: University of Massachusetts Lowell Next Generation Sequencing and Genomics Core Facility (RRID:SCR_024981) Copy
https://www.bidmc.org/research/core-facilities/ncrna-core
Delivery Unit offers training and services on the NanoAssemblr Spark, NanoAssemblr Ignite+, and Malvern Zetasizer for the purpose of synthesis and characterisation of Lipid Nanoparticles (LNPs). The Zetasizer is able to read zeta potential and size of particles, including exosomes, liposomes, and LNPs.
Proper citation: Beth Israel Deaconess Medical Center Precision RNA Medicine Delivery Unit Core Facility (RRID:SCR_024862) Copy
https://www.wistar.org/our-science/shared-facilities/molecular-screening-protein-expression-facility
Facility enables to discover molecular, genetic, and small molecule compounds suitable to study functions of poorly understood proteins, signaling pathways, and cells in complex biological processes relevant to human physiology and disease; provides technical assistance with viral vector preparation and expression and purification of recombinant proteins; fosters collaborations. Staff will also develop and implement new technology as needed. Education and training is also available. Provides opportunities to develop new innovative basic and translational research, preliminary data for hypothesis driven research grant applications, and public-private partnerships.
Proper citation: Wistar Institute Molecular Screening and Protein Expression Core Facility (RRID:SCR_024978) Copy
https://www.uml.edu/research/crf/ourlabs/nuc-mag-res-lab.aspx
Core provides JEOL 400 MHz NMR equipped with auto sampling and automatic tuning and matching. Instrument can perform temperature and kinetic studies as well as x-nuclei and 2D experiments.
Proper citation: University of Massachusetts Lowell Nuclear Magnetic Resonance Spectroscopy Lab Core Facility (RRID:SCR_024979) Copy
https://noncodingrna.org/detection-unit/
Detection Unit of ncRNA Core can perform highly sensitive microRNA detection platform for diverse biospecimens.Technology is based on qPCR and uses single plate panel for simultaneous detection of 384 miRNAs using MIRXES technology. Services offered by unit include Detection of miRNA, Analysis of dysregulated miRNA,Consultation and support for non-coding RNA biology and research.
Proper citation: Beth Israel Deaconess Medical Center Precision RNA Medicine Detection Unit Core Facility, (RRID:SCR_024819) Copy
https://research.lsuhs.edu/cores/research-core-facilities/high-throughput-screening-inlet
Facility focused on discovery and development of drugs and genetic targets that affect human diseases including cancer, fungal, bacterial and viral infection, neurological disorders and cardiovascular disorders. Both live and fixed high throughput microscopy is performed using Incucyte S3, Incucyte SX5 and Cellomics ArrayScan VTI HCS Reader. Provides expertise and protocol design for variety of assays including: Cell proliferation, Cell viability, Phagocytosis, Chemotaxis, Cell migration/invasion, 3D spheroid growth. INLET Core provides cutting edge, multiplexed functional imaging platforms to perform multi-well high-throughput live-cell imaging and analysis assays., THIS RESOURCE IS NO LONGER IN SERVICE. Documented on September 16,2025.
Proper citation: Louisiana State University Health Sciences Shreveport INLET High Throughput Screening Core Facility (RRID:SCR_024990) Copy
Core for proteomics technology development and service. Provides mass spectrometry analytical services to academic, industrial, and government laboratories.
Proper citation: University of Victoria Genome BC Proteomics Centre Core Facility (RRID:SCR_024904) Copy
https://www.baderc.org/cores/functional-genomics-and-bioinformatics-core/
Core provides consultative, laboratory, and bioinformatic services for next generation sequencing based applications.Core services include Pre- and post-experimental consultation to determine proper experimental approach, design, and interpretation; Standalone RNA preparation, RNA and DNA Bioanalyzer analyses, chromatin shearing/shear checks; Sample quality assessment of DNA and RNA using the BioAnalyzer and Qubit assays; Library preparation, sequencing, and analysis of transcriptomes (RNA-seq), cistromes (ChIP-seq), chromatin accessibility (ATAC-seq); Standalone sequencing on NextSeq500; Multiplexed 10x Single Cell/Nucleus Library RNA-seq Droplet generation, Library Preparation; Basic data analysis: quality assessment and normalization, genomic alignment, differential expression/enrichment, functional enrichment analysis (overrepresentation and GSEA), sample clustering, and motif enrichment; Bespoke data analysis, including integration of complex ChIP-seq and RNA-seq data sets, single-cell sequencing analyses.Core is located on the 7th floor of the Center for Life Sciences building in the Longwood Medical area (3 Blackfan Circle, CLS-728).
Proper citation: Beth Israel Deaconess Medical Center Functional Genomics and Bioinformatics Core Facility (RRID:SCR_024877) Copy
Core specializes in metabolomic analysis. Provides Orbitrap Exploris 240 mass spectrometer, as well as dedicated staff for consultation and the analysis of biological samples.
Proper citation: University of Rochester Medical Center Metabolomics Resource Core Facility (RRID:SCR_024998) Copy
https://tnprc.tulane.edu/veterinary-medicine-research-resources
Unit is part of Tulane National Primate Research Center. Provides services including routine husbandry care for animal colonies, reporting of animals abnormal clinical signs or activities to veterinary medical staff and faculty. Animal Care Technicians provide support during diagnostic and therapeutic procedures and administration of preventive medicine program. Coordinates its activities with research personnel to provide assistance, equipment and support for their work. After hours care includes administration of treatments, collection of biologic samples for research activities and observation of animals. TNPRC facilities are accredited by Association for Assessment and Accreditation of Laboratory Animal Care International (AAALAC).
Proper citation: Tulane University TNBRC Animal Resources (RRID:SCR_024911) Copy
https://eelliottnew.weebly.com/pitt-isotope-tracers-lab.html
One of several isotope labs in Department of Geology and Environmental Science formerly known as Regional Stable Isotope Lab for Earth and Environmental Science Research, has capacity for wide variety of isotopic measurements in multitude of sample media. Capabilities include: Nitrate (?15N, ?18O, D17O);Greenhouse and trace gases like carbon dioxide (?13C, ?18O), nitrous oxide (?15N, ?18O), methane (?13C); Nitrogen, carbon, and sulfur (?15N, ?13C, ?34S) in organic and other solid materials (e.g., biota, soils);Ammonium (?15N); Dry reactive nitrogen deposition (?15N-NH3, ?15-NO2, and ?15N-HNO3); and Carbonates (?13C, ?18O).
Proper citation: University of Pittsburgh Dietrich School of Arts and Sciences Pitt Isotope Tracer Lab Core Facility (RRID:SCR_025145) Copy
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