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SciCrunch Registry is a curated repository of scientific resources, with a focus on biomedical resources, including tools, databases, and core facilities - visit SciCrunch to register your resource.
https://chemh.stanford.edu/research/knowledge-centers/protein-engineering
MSKC is main gateway for Stanford faculty and students interested to study biological molecules using SLAC X-ray facilities and other major bioimaging facilities.
Proper citation: Stanford Sarafan Protein Engineering Knowledge Center Core Facility (RRID:SCR_023237) Copy
https://chemh.stanford.edu/research/knowledge-centers/metabolomics
Provides scientific expertise and instrumentation for measurement of small molecules such as metabolites and lipids to ChEM-H and Stanford communities. Leverages expertise in mass spectrometry and allied techniques to understand biology of small molecules both metabolites and xenobiotics and to apply that understanding to advances in human health.
Proper citation: Stanford Sarafan Metabolomics Knowledge Center Core Facility (RRID:SCR_023236) Copy
Provides equipment and expertise for analysis of variety of biological and small molecules.Services include protein analysis encompassing protein identification, protein and peptide sequence confirmation, intact protein molecular weight determination, complex protein sample analysis, and protein/antibody drug interactions.Developed metabolomics library to support metabolomic and lipidomics analysis. Can identify range of post-translational modifications, determining their presence or absence, as well as quantitating PTMs.Proteomics and small molecule services include workflows for label free,chemical labeling (iTRAQ/TMT) and metabolic labeling (SILAC).Service for molecular synthesis, with monitoring reaction steps,calculating percentage of product, testing for purity, and molecule characterization with high resolution and high mass accuracy.Provides molecular weight and chemical composition determinations, structure elucidations and compound identification analysis or confirmation and accurate mass measurements of synthetic products, measurement of polymers, nucleic acids (DNA/RNA), peptides, proteins, natural products, and assistance with determination of unknowns.
Proper citation: University of Arizona Analytical and Biological Mass Spectrometry Core Facility (RRID:SCR_023370) Copy
http://www.arpege.cnrs.frCore FacilityArpege
Offers functional and structural analysis of protein complexes.Offers possibility to characterize all types of molecular interactions: ligand-target binding, protein-protein interactions, signal transduction, and signalling complexes. Staff members are skilled specialists in luminescence-based techniques and in receptor biology.Application portfolio includes Analysis of cell signalling, by measuring signal transduction;Ligand-target binding (pharmacological analysis, affinity, selectivity); Protein-protein interactions (oligomerization, effectors...); Activation of signalling pathways (G proteins, GRK, arrestins & internalization); Intracellular production of second messengers (cAMP, IP1, Ca2+); Phosphorylation of signalling proteins (ERK, AKT...); Measurement of global cell functions and of different cell parameters (proliferation, migration, invasion...).
Proper citation: Arpege Core Facility (RRID:SCR_023092) Copy
Offers genomic technologies to academic laboratories and biotechnology companies.Application portfolio includes Whole genome (re)sequencing, including the identification of variants (SNVs, mutations, indels, CNVs);Targeted sequencing, for instance exomes; Transcriptome analyses (RNA-Seq, small RNA-Seq, microarrays), including in single cells (single-cell 3 RNA-seq); Determination of chromatin structure and dynamics (ChIP-Seq, FAIRE-Seq, Hi-C); Epigenetic analyses (ChIP-Seq, RRBS, Bisulphite-Seq);Genotyping (RAD-Seq, GBS, microarrays).
Proper citation: Montpellier GenomiX Core Facility (RRID:SCR_023091) Copy
Provides microscopy expertise and access to high resolution, state-of-the-art imaging technologies to Stanford University and surrounding academic and biotech researchers. Core provides training, design, implementation, and analysis assistance.
Proper citation: Stanford Neuroscience Microscopy Service Core Facility (RRID:SCR_023257) Copy
Provides preclinical Magnetic Resonance Imaging technology and expertise to Stanford community. Offers range of support from full project to independent user operation and training.
Proper citation: Stanford Neuroscience Preclinical Imaging Laboratory Core Facility (RRID:SCR_023254) Copy
https://geochronology.stanford.edu/
Core for comprehensive examination of evolution of Earth's crust using geochronologic approaches. Provides spectrum of analytical facilities that are all housed within School of Earth, Energy and Environmental Sciences.Provides data to many disciplines throughout geosciences, including tectonics, geodynamics, petrology, geochemistry, geomorphology, sedimentology, stratigraphy, paleontology, and paleoclimatology.
Proper citation: Stanford Geochronology Cluster Core Facility (RRID:SCR_023252) Copy
https://www.crg.eu/en/programmes-groups/bioinformatics-unit
Provides services of consultation, planning NGS and other genomic experiments, NGS data processing, analysis and management, software and database development, bioinformatics training, and access to high-performance computing resources at CRG. The Unit works in synergy with the Genomics Unit and the Biomolecular Screening and Protein Technologies Unit to support users using high throughput sequencing technologies from experiment planning to delivery of timely and reliable results.
Proper citation: Centre for Genomic Regulation Bioinformatics Unit Core Facility (RRID:SCR_023373) Copy
https://www.rockefeller.edu/crispr/
Provides gene targeting and mouse embryonic stem cell technology for members of Rockefeller University, Memorial Sloan-Kettering Cancer Center and their collaborators.CRISPR and Genome Editing services include mouse genomic knock-out and knock-in, mouse conditional knock-out, establishing new ES lines for gene targeting services, establishing ES lines from mutant mouse embryos, preparing ES cells introduced from off campus resources for injection or other application, assisting in embryoid body culture and in vitro differentiation of ES cells, and purification and evaluation of DNA for pronuclear injection.
Proper citation: Rockefeller University CRISPR and Genome Editing Resource Center Core Facility (RRID:SCR_023097) Copy
https://www.crg.eu/en/programmes-groups/advanced-light-microscopy-unit
Core provides support with experimental design, sample preparation, acquisition, bioimage analysis and visualization.Consists of microscope systems specifically designed for fluorescence microscopy ranging from confocal, widefield to super resolution systems and helps reveal structures from macro to nanoscale.
Proper citation: Centre for Genomic Regulation Advanced Light Microscopy Unit Core Facility (RRID:SCR_023371) Copy
Laboratory at Wu Tsai Neursciences Institute provides preclinical discovery platform for central nervous system target validation in preclinical in vivo and in vitro models. Neurobehavioral assessment tools in CNS disease models provide platform for screening and profiling of experimental therapeutics and genetic rodent models. Used to support understanding of human CNS disorders and development of therapeutic interventions.
Proper citation: Stanford Behavioral and Functional Neuroscience Laboratory Core Facility (RRID:SCR_023249) Copy
Small animal imaginig service center.Instruments range from systems typically found in clinical setting, but scaled for rodent usage (such as MRI, PET, CT and ultrasound), optical systems for measuring bioluminescence, fluorescence, and Cherenkov light (IVIS, Ami, Lago and Maestro systems), new modalities (MPI and photoacoustic), as well as access to advanced image analysis software, computer workstations, and surgical preparation areas. Scientists are trained to use instruments independently and can schedule studies as needed.
Proper citation: Stanford University School of Medicine Center for Innovation in In vivo Imaging Core Facility (RRID:SCR_023345) Copy
https://med.stanford.edu/lucasmri.html
Houses four whole-body MRI systems (three 3.0T, one 7.0T). 3T2 and 3T3 are part of the Lucas Service Center. Individual researchers are trained in magnet safety and scanner operations by the magnet manager or MR research technologists.
Proper citation: Stanford University School of Medicine Richard M. Lucas Center for Imaging Core Facility (RRID:SCR_023344) Copy
https://med.stanford.edu/invitrobsl3
Center consists of Virology BSL3 lab, separate BSL3 Bacteriology lab, and BSL2 lab. It is operated by School of Medicine as scientific service center and is open to all Stanford researchers after adequate training and subsequent use.
Proper citation: Stanford University School of Medicine In Vitro Biosafety Level3 Service Center Core Facility (RRID:SCR_023342) Copy
https://www.bridge-center.org/
Collaborative MRI facility that is jointly operated by the University of Pittsburgh and Carnegie Mellon University. Research neuroimaging facility, with focus on advanced data analytics and basic science research. Designed to support basic science research and next generation of brain scientists.
Proper citation: Carnegie Mellon University Pitt Brain Imaging Data Generation and Education Center Core Facility (RRID:SCR_023356) Copy
One of four labs that are part of nano@stanford, under NSF National Nanotechnology Coordinated Infrastructure program. SNF includes cleanroom housing tools for device fabrication, satellite labs supporting Metal Organic Chemical Vapor Deposition,Experimental Fabrication methods and electronics shop for Systems Prototyping. SNF supports researchers in applications ranging from medicine and biology to fundamental physics and astronomy.
Proper citation: Stanford Nanofabrication Core Facility (RRID:SCR_023234) Copy
http://microscopy.arizona.edu/facility/imaging-cores-optical
Facility with two locations:Marley and Life Sciences North. Dedicated to acquisition of images for research, industrial and clinical applications.Marley location features inverted point scanning confocal microscope, upright confocal/multiphoton microscope with superresolution capabilities, fluorescence stereo microscope and research quality microwave. Life Sciences North location features superresolution fluoresence microscope:structured illumination, SIM; inverted multifunction widefield microscope:color brightfield, polarized light, fluorescence; image analysis workstation.
Proper citation: University of Arizona Imaging Cores Optical Core Facility (RRID:SCR_023355) Copy
Service center and teaching lab focusing on molecular structural-functional studies. Jointly established by Sarafan ChEM-H, School of Engineering and SLAC National Accelerator Laboratory. Provides Stanford researchers with expertise, training and instruments for techniques in spectroscopy, bioimaging, crystallography, and scattering and diffraction.
Proper citation: Stanford Sarafan Macromolecular Structure Knowledge Center Core Facility (RRID:SCR_023233) Copy
https://www.urmc.rochester.edu/research/cold-storage-core.aspx
Provides controlled environment designed for long term storage of clinical/research materials in -20C or -80C freezers and in liquid nitrogen freezers.
Proper citation: University of Rochester Medical Center Cold Storage Core Facility (RRID:SCR_023197) Copy
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