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http://eagle-i.ea.vanderbilt.edu/i/00000139-114b-ebaa-dacb-da6080000000

Core facility that provides the following services: Assay Design and Development, High Throughput Screening and automated data analysis. The biology and screening team is responsible for developing, adapting, and automating the HTS assay from the benchtop assay provided by the collaborator. We work closely with the providing researcher to insure that the assay is rapidly moved into high-throughput screening. Once the assay has been validated, the screening of the small molecule library begins. Generally, the screen is expanded to accommodate the full compound library; however, structure-specific searches can be made if the required reagents are limited or costly.

Proper citation: Vanderbilt High Throughput Screening Facility (RRID:SCR_010180) Copy   

•   Source: SciCrunch Registry

http://utsa.eagle-i.net/i/00000135-5f47-d5a9-d7c8-cf3780000000

This laboratory houses an impressive collection of high-end microscopes including one of the most powerful transmission electron microscopes in the world. The microscope is kept in a specially designed space that inhibits intrusive vibrations. Its atomic resolution is propelling world-class research in nanotechnology, biology, chemistry, geology, engineering and medicine. The laboratory''s microscopes are accessible to trained collaborators from other institutions.

Proper citation: UTSA Kleberg Advanced Microscopy Laboratory (RRID:SCR_010146) Copy   

•   Source: SciCrunch Registry

http://utsa.eagle-i.net/i/00000135-2f42-aa68-d7c8-cf3780000000

Core facility that provides the following services: Computational systems biology data analysis assistance, Biological computational software installation service. The objective of the Computational Systems Biology Core facility (CSBC) is to provide computational support for basic and translational health research at UTSA with the following specific aims: - Build the computational infrastructure to support modeling and simulation of biological systems - Live cell imaging - Protein Biomarker research

Proper citation: UTSA RCMI Computational Systems Biology Core (RRID:SCR_010148) Copy   

•   Source: SciCrunch Registry

http://utsa.eagle-i.net/i/00000135-f9ee-8ac6-3c2e-1e5380000000

The mission of The Neurostatistics Core is to promote the use of the most effective and current biostatistical methods among Neuroscience faculty and students, and to make these methods more generally available. It is designed to overcome the communication gap between experimental neuroscientists and statisticians by integrating statistical experts, in the form of Applied Biostatistics PhD students, directly into the laboratories of SNRP Project Investigators.

Proper citation: UTSA SNRP Neurostatistics Core (RRID:SCR_010153) Copy   

•   Source: SciCrunch Registry

http://eagle-i.ea.vanderbilt.edu/i/0000013d-037f-b425-afc0-9aeb80000000

VANTAGE (Vanderbilt Technologies for Advanced Genomics) is a genomics core laboratory consolidation initiated by an $8.6 million ARRA funded NIH grant award to Vanderbilt University Medical Center, with an overall goal of creating a new collaborative shared resource that accelerates discovery in genome sciences and personalized medicine, providing state-of-the art research shared resource facilities and technology.

Proper citation: VANTAGE (RRID:SCR_010155) Copy   

•   Source: SciCrunch Registry

http://eagle-i.ea.vanderbilt.edu/i/00000139-a235-587c-b4bd-8a1180000000

The Informatics Shared Resource catalyzes the research productivity of VICC investigators by providing a flexible physical and electronic infrastructure for acquiring, storing, communicating and analyzing data arising from wet bench, translational, and clinical cancer research as well as senior staff and faculty level assistance in the interpretation of research datasets using state-of-the-art analysis.

Proper citation: VICC Research Informatics (RRID:SCR_010156) Copy   

•   Source: SciCrunch Registry

http://eagle-i.ea.vanderbilt.edu/i/00000139-114e-e025-dacb-da6080000000

Core facility that provides the following services: Custom Polyclonal Antibody Services, Monoclonal antibody isotyping, Hybridoma Services, Antigen production and purification, Peptide Synthesis, Peptide conjugation to protein carriers (ex. KLH, BSA), Recombinant Protein Expression and Purification Services, Kinetic Analyses for Protein:Protein and Protein:Small Molecule Interactions, Sample Lysis and Preparation. The Vanderbilt Antibody and Protein Resource (VAPR) partners both with scientists locally and from across the country to design and develop reagents for research, diagnostics, and large-molecule therapeutics.

Proper citation: Vanderbilt Antibody and Protein Resource (RRID:SCR_010158) Copy   

•   Source: SciCrunch Registry

http://eagle-i.ea.vanderbilt.edu/i/00000139-c62b-0ffa-b341-4bb480000000

Core facility that provides the following services: Biospecimen processing and analysis, DNA/RNA extraction and banking, Genotyping. The Molecular Epidemiology Laboratory provides genotyping and other lab services for large-scale studies to Vanderbilt investigators related to biological specimen collection and storage, as well as biomarker and genetic marker assays.

Proper citation: Vanderbilt Biospecimen Shared Resource (RRID:SCR_010162) Copy   

•   Source: SciCrunch Registry

http://eagle-i.ea.vanderbilt.edu/i/00000139-1124-673f-dacb-da6080000000

The Center for Molecular Neuroscience (CMN) at the Vanderbilt University School of Medicine supports interdisciplinary research and training in cellular and molecular neurobiology. Internationally recognized faculty approach the intricacies of neurogenesis, neural signaling and synaptic plasticity using leading-edge techniques in state-of-the-art research facilities.

Proper citation: Vanderbilt Center for Molecular Neuroscience Cores (RRID:SCR_010166) Copy   

•   Source: SciCrunch Registry

http://upr.eagle-i.net/i/0000012b-547c-89f8-0b67-095480000000

The Pharmaceutical Sciences Research Support Unit responds directly to the Chair of the Pharmaceutical Sciences Department. Its mission is to promote research by making available to offering our investigators instruments such as HPLCs, GC-MSs, NMR, among others and facilitating physical complementary spaces.

Proper citation: UPR Pharmaceutical Science Research Support Unit (RRID:SCR_010131) Copy   

•   Source: SciCrunch Registry

http://upr.eagle-i.net/i/0000012a-250d-df05-43fb-601a80000000

The Translational Proteomics Center provides training, resources, and tools for new and established investigators seeking to use innovative approaches of proteomics to their research, as well as to undergraduate and graduate students in the biomedical field. The Center fosters collaborations and partnerships among researchers aiming to reduce health disparities, including infectious diseases, cancer, and neurological/neurodegenerative diseases. Currently located at the second floor of the Comprehensive Cancer Center, Laboratory # 5.

Proper citation: UPR RCMI Translational Proteomics Center (RRID:SCR_010133) Copy   

•   Source: SciCrunch Registry

http://upr.eagle-i.net/i/0000012c-9dd1-fddf-95a5-371e80000000

Core facility that provides the following services: Necropsy. The Sabana Seca Field Station (SSFS) is the administrative headquarters for the Caribbean Primate Research Center, or CPRC. This area contains offices, a clinic, and laboratories for reproductive biology and bone densitometry, necropsy and maintenance buildings. It houses rhesus monkeys from the CS colony or from the CS genetic line.

Proper citation: UPR Sabana Seca Field Station Caribbean Primate Research Center (RRID:SCR_010134) Copy   

•   Source: SciCrunch Registry

http://upr.eagle-i.net/i/0000012c-2bf2-d33a-5b95-f21080000000

Core facility that provides the following services: RNA extraction, Immunofluoresence assay, Dendritic cell immunophenotyping, ELISA, Polymerase chain reaction service, Florescence activated cell sorting service, Western blot analysis service. Research interests include: immunogenicity and protective efficacy of multi-clade consensus ENV SHIV virus-like particle vaccine, cellular innate activation as a tactic to prevent HIV-1 transmission, molecular changes after serial DV infections in macaques, and immunization of rhesus macaques with a dengue vaccine candidate based on a Venezuelan Equine Encephalitis (VEE) replicon vector.

Proper citation: UPR Virology Laboratory (RRID:SCR_010136) Copy   

•   Source: SciCrunch Registry

http://utep.eagle-i.net/i/00000134-aa21-2db4-bfc0-fe9780000000

Core facility that provides the following services: Confocal microscope access, Flow cytometry analyzer access, FACS Cell Sorting, Cell culture technique training, Cryopreservation of cultured cells, Cell culture analysis assistance, Preparation of high titer viral stock, Flow cytometry for cytotoxicity assay, Viral plaque assay, Real-time imaging of cell cultures, Mycoplasma testing, Treatment of cell lines contaminated with mycoplasma, Provide SF-9 cell suspension, Establishment of seed stocks, AnnexinV-FITC/PI assay. The Cell Culture and High Throughput Screening (HTS) Core Facility is a comprehensive research cell-culturing and cytometry facility established in 2007, as part of the Border Biomedical Research Center (BBRC). This facility was conceived to provide investigators, students and other researchers access to state-of-the-art technology for conducting experiments related to cellular, immune and physiological responses to stress, infectious agents, and toxicants. The laboratory also provides assistance and training related to cell culture techniques and equipment operation . The 1,756 sq ft core facility includes 6 individual cell culture suites that are available 24/7 to any researchers that have completed in-house training. The core also provides customized project support for experimental design and data analysis. The integration of the Cell Culture and HTS Core Laboratories has allowed investigators to screen a large number of compounds for their therapeutic potential against pathogens, cancer, and other diseases.

Proper citation: UTEP Cell Culture and High Throughput Screening Core Facility (RRID:SCR_010140) Copy   

•   Source: SciCrunch Registry

http://utep.eagle-i.net/i/00000134-aa23-3d2b-bfc0-fe9780000000

Core facility that provides the following services: DNA Sequencing Service, DNA/protein microarray printing. The DNA Analysis Core Facility supports researchers in their nucleic acid-based research studies on a 24/7 basis. The facility provides access to a wide range of genomic research tools including: DNA sequencing; microsatellite and fragment length polymorphism analysis; quantitative and real-time PCR; microarray analysis; and sophisticated nucleic acid analysis software. The DNA Analysis Core Facility services are available to external researchers from the RCMI program and other institutions for a nominal fee.

Proper citation: UTEP DNA Analysis Core Facility (RRID:SCR_010141) Copy   

•   Source: SciCrunch Registry

http://utep.eagle-i.net/i/00000134-aa24-006d-bfc0-fe9780000000

The long-term goal of the Statistical Consulting Laboratory (SCL) is to be a regional resource for the statistical support of basic science research, clinical or population based research, and evaluation of interventions designed to address issues of health and health disparities in the region''s population. As a major component of the Border Biomedical Research Center (BBRC), the Statistical Consulting Lab will continue to serve as a focal point from which all BBRC participants may obtain statistical and computing support for both their research and for the education of students in the graduate programs of the Biological Sciences Department. Statistical support is provided by a Ph.D. level staff statistician and five resource statisticians (counting the SCL core director) in the Department of Mathematical Sciences.

Proper citation: UTEP Statistical Consulting Laboratory (RRID:SCR_010142) Copy   

•   Source: SciCrunch Registry

http://utsa.eagle-i.net/i/00000135-783e-3187-d7c8-cf3780000000

The new Biophysics facility is committed towards providing computational biology tools and software designed to study the physical phenomena underlying the behavior of biological systems. Shortly, this facility will be furnished with a 6-quadcore server and 4 workstations with high resolution graphics capabilities and support for many simultaneous remote users. All these computing resources will be linked via 10GB optical wires. On the other hand, the Departmental network provides high speed access to the University Computer Center main-ports and Internet. As an extension of its functionality and performance, this facility will also share resources with the Computational Biology innovative at the Biology Department. A major goal is devoted to establishing the connection between this facility and the supercomputers at the Texas Advanced Computing Center (TACC) at 10GB data rate. This facility is currently used by the computational and theoretical biophysics researchers at the Department of Physics to study the properties of biomolecules that are strongly affected by their surrounding aqueous and ionic environment.

Proper citation: UTSA Biophysics Facility (RRID:SCR_010143) Copy   

•   Source: SciCrunch Registry

http://utsa.eagle-i.net/i/00000135-5d41-3cac-d7c8-cf3780000000

These laboratories are dedicated to ''Cellular and Tissue Engineering'' research activities which focus on in vitro studies of mammalian cell and protein interactions with material substrates, biomaterials (including nanostructured ones), biocompatibility, and the effect of select biochemical and biophysical (specifically, sustained and cyclic pressure and electrical) stimuli on mammalian cell function pertinent to new tissue formation and regeneration.

Proper citation: UTSA Cellular and Tissue Engineering Laboratory (RRID:SCR_010144) Copy   

•   Source: SciCrunch Registry

http://utsa.eagle-i.net/i/00000135-f9b6-93ba-3c2e-1e5380000000

The High Performance Computing Center/Computational Biology Initiative (HPC/CBI) is a new interdisciplinary initiative at the University of Texas Health Science Center at San Antonio (UTHSCSA) and the University of Texas at San Antonio (UTSA) which was launched in January 2005. The overall goal of the initiative is to build infrastructure to significantly advance collaborative interdisciplinary bioscience research in San Antonio.

Proper citation: UTSA Computational Biology Initiative (RRID:SCR_010145) Copy   

•   Source: SciCrunch Registry

http://eagle-i.ea.vanderbilt.edu/i/00000139-2ff7-d10c-dacb-da6080000000

The objectives of the physiology core are to establish average values and normal ranges for physiologic parameters of renal function in mice, and to develop novel assays of mouse kidney structure and function. Our goal is to provide valuable institutional and national shared resources to facilitate better understanding of kidney diseases and treatments.

Proper citation: Vanderbilt Mouse Kidney Physiology Core Lab (RRID:SCR_010193) Copy   

•   Source: SciCrunch Registry