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SciCrunch Registry is a curated repository of scientific resources, with a focus on biomedical resources, including tools, databases, and core facilities - visit SciCrunch to register your resource.

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Resource Name Proper Citation Abbreviations Resource Type Description Keywords Resource Relationships Related Condition Funding Defining Citation Availability Website Status Alternate IDs Alternate URLs Old URLs Parent Organization Resource ID Synonyms Record Last Update Mentions Count
MACAT
 
Resource Report
Resource Website
MACAT (RRID:SCR_001350) MACAT software resource Software library that contains functions to investigate links between differential gene expression and the chromosomal localization of the genes. It is motivated by the common observation of phenomena involving large chromosomal regions in tumor cells. MACAT is the implementation of a statistical approach for identifying significantly differentially expressed chromosome regions. differential expression, microarray, visualization, bio.tools is listed by: OMICtools
is listed by: bio.tools
is listed by: Debian
has parent organization: Bioconductor
PMID:15572464 THIS RESOURCE IS NO LONGER IN SERVICE OMICS_01989, biotools:macat https://bio.tools/macat SCR_001350 MicroArray Chromosome Analysis Tool 2026-02-07 02:05:36 0
nnNorm
 
Resource Report
Resource Website
nnNorm (RRID:SCR_001354) nnNorm software resource Software package that allows to detect and correct for spatial and intensity biases with two-channel microarray data. The normalization method implemented in this package is based on robust neural networks fitting. microarray, preprocessing is listed by: OMICtools
has parent organization: Bioconductor
Free, Available for download, Freely available OMICS_01985 SCR_001354 nnNorm - Spatial and intensity based normalization of cDNA microarray data based on robust neural nets 2026-02-07 02:05:30 0
maCorrPlot
 
Resource Report
Resource Website
1+ mentions
maCorrPlot (RRID:SCR_001348) maCorrPlot software resource Software that graphically displays correlation in microarray data that is due to insufficient normalization. microarray, preprocessing, visualization is listed by: OMICtools
has parent organization: Bioconductor
PMID:15799785 Free, Available for download, Freely available OMICS_01991 SCR_001348 maCorrPlot - Visualize artificial correlation in microarray data 2026-02-07 02:05:30 2
lapmix
 
Resource Report
Resource Website
lapmix (RRID:SCR_001347) lapmix software resource Software to identify differentially expressed genes. A hierarchical Bayesian approach is used, and the hyperparameters are estimated using empirical Bayes. differential expression, microarray, bio.tools is listed by: OMICtools
is listed by: Debian
is listed by: bio.tools
has parent organization: Bioconductor
Free, Available for download, Freely available biotools:lapmix, OMICS_01992 https://bio.tools/lapmix SCR_001347 Laplace Mixture Model in Microarray Experiments 2026-02-07 02:05:36 0
FARMS
 
Resource Report
Resource Website
10+ mentions
FARMS (RRID:SCR_001344) FARMS software resource Software using a model-based technique for summarizing high-density oligonucleotide array data at probe level for Affymetrix GeneChips. It is based on a factor analysis model for which a Bayesian maximum a posteriori method optimizes the model parameters under the assumption of Gaussian measurement noise. oligonucleotide array, probe, affymetrix genechip, r, unix, windows, microarray, summarization, bio.tools is listed by: OMICtools
is listed by: bio.tools
is listed by: Debian
has parent organization: Johannes Kepler University of Linz; Linz; Austria
PMID:16473874 Free, Freely Available OMICS_01995, biotools:farms https://bio.tools/farms SCR_001344 Factor Analysis for Robust Microarray Summarization 2026-02-07 02:05:36 28
OCplus
 
Resource Report
Resource Website
1+ mentions
OCplus (RRID:SCR_001342) OCplus software resource Software package that allows to characterize the operating characteristics of a microarray experiment, i.e. the trade-off between false discovery rate and the power to detect truly regulated genes. The package includes tools both for planned experiments (for sample size assessment) and for already collected data (identification of differentially expressed genes). differential expression, microarray, multiple comparison is listed by: OMICtools
has parent organization: Bioconductor
PMID:16368770 Free, Available for download, Freely available OMICS_01999 SCR_001342 Ocplus - Operating characteristics plus sample size and local fdr for microarray experiments 2026-02-07 02:05:30 1
bridge
 
Resource Report
Resource Website
100+ mentions
bridge (RRID:SCR_001343) bridge software resource Software package to test for differentially expressed genes with microarray data. It can be used with both cDNA microarrays or Affymetrix chip. The packge fits a robust Bayesian hierarchical model for testing for differential expression. Outliers are modeled explicitly using a $t$-distribution. The model includes an exchangeable prior for the variances which allow different variances for the genes but still shrink extreme empirical variances. The model can be used for testing for differentially expressed genes among multiple samples, and can distinguish between the different possible patterns of differential expression when there are three or more samples. Parameter estimation is carried out using a novel version of Markov Chain Monte Carlo that is appropriate when the model puts mass on subspaces of the full parameter space. cdna microarray, affymetrix chip, differential expression, microarray, bio.tools is listed by: OMICtools
is listed by: Debian
is listed by: bio.tools
has parent organization: Bioconductor
PMID:16542223 Free, Available for download, Freely available OMICS_01996, biotools:bridge http://www.bioconductor.org/packages/release/bioc/html/bridge.html SCR_001343 Bayesian Robust Inference for Differential Gene Expression 2026-02-07 02:05:31 154
CALIB
 
Resource Report
Resource Website
100+ mentions
CALIB (RRID:SCR_001338) CALIB software resource Software package that contains functions for normalizing spotted microarray data, based on a physically motivated calibration model. The model parameters and error distributions are estimated from external control spikes. microarray, preprocessing is listed by: OMICtools
has parent organization: Bioconductor
PMID:17485432 Free, Available for download, Freely available OMICS_02003 http://www.bioconductor.org/packages/release/bioc/html/CALIB.html SCR_001338 2026-02-07 02:05:36 131
LPE
 
Resource Report
Resource Website
LPE (RRID:SCR_001364) LPE software resource Software library used to do significance analysis of microarray data with small number of replicates. It uses resampling based FDR adjustment, and gives less conservative results than traditional "BH" or "BY" procedures. Data accepted is raw data in txt format from MAS4, MAS5 or dChip. Data can also be supplied after normalization. LPE library is primarily used for analyzing data between two conditions. differential expression, microarray is listed by: OMICtools
has parent organization: Bioconductor
PMID:18450812 Free, Available for download, Freely available OMICS_01978 SCR_001364 Local Pooled Error 2026-02-07 02:05:36 0
aroma.light
 
Resource Report
Resource Website
1+ mentions
aroma.light (RRID:SCR_001312) aroma.light software resource Light-weight software package for normalization and visualization of microarray data using only basic R data types. Software can be used standalone, be utilized in other packages, or be wrapped up in higher-level classes. infrastructure, microarray, preprocessing, visualization, bio.tools is listed by: OMICtools
is listed by: Debian
is listed by: bio.tools
has parent organization: Bioconductor
DOI:10.1186/1471-2105-11-245 Free, Available for download, Freely available OMICS_01998, biotools:aroma.light https://bio.tools/aroma.light
https://sources.debian.org/src/r-bioc-aroma.light/
SCR_001312 2026-02-07 02:05:29 1
BeadDataPackR
 
Resource Report
Resource Website
BeadDataPackR (RRID:SCR_001310) BeadDataPackR software resource Software that provides functionality for the compression and decompression of raw bead-level data from the Illumina BeadArray platform. microarray, bio.tools is listed by: OMICtools
is listed by: bio.tools
is listed by: Debian
has parent organization: Bioconductor
PMID:20981138 Free, Available for download, Freely available biotools:beaddatapackr, OMICS_02023 https://bio.tools/beaddatapackr SCR_001310 BeadDataPackR - Compression of Illumina BeadArray data 2026-02-07 02:05:35 0
OLIN
 
Resource Report
Resource Website
10+ mentions
OLIN (RRID:SCR_001304) OLIN software resource Software functions for normalization of two-color microarrays by optimised local regression and for detection of artifacts in microarray data. r, normalization, visualization, quality control, two-channel, microarray, preprocessing, bio.tools is listed by: OMICtools
is listed by: bio.tools
is listed by: Debian
has parent organization: Humboldt University of Berlin; Berlin; Germany
has parent organization: Bioconductor
PMID:15585527 Free, Available for download, Freely available biotools:olin, OMICS_02029 http://itb.biologie.hu-berlin.de/~futschik/software/R/OLIN/index.html SCR_001304 Optimised Local Intensity-dependent Normalisation 2026-02-07 02:05:35 18
qcmetrics
 
Resource Report
Resource Website
1+ mentions
qcmetrics (RRID:SCR_001303) qcmetrics software resource Software package that provides a framework for generic quality control of data. It permits to create, manage and visualise individual or sets of quality control metrics and generate quality control reports in various formats. mass spectrometry, microarray, proteomics, quality control, visualization, bio.tools is listed by: OMICtools
is listed by: Debian
is listed by: bio.tools
has parent organization: Bioconductor
Free, Available for download, Freely available OMICS_02032, biotools:qcmetrics, BioTools:qcmetrics https://bio.tools/qcmetrics
https://bio.tools/qcmetrics
https://bio.tools/qcmetrics
SCR_001303 qcmetrics - A Framework for Quality Control 2026-02-07 02:05:30 1
DEXUS
 
Resource Report
Resource Website
1+ mentions
DEXUS (RRID:SCR_001309) DEXUS software resource Software package that identifies differentially expressed genes in RNA-Seq data under all possible study designs such as studies without replicates, without sample groups, and with unknown conditions. It works also for known conditions, for example for RNA-Seq data with two or multiple conditions. RNA-Seq read count data can be provided both by the S4 class Count Data Set and by read count matrices. Differentially expressed transcripts can be visualized by heatmaps, in which unknown conditions, replicates, and samples groups are also indicated. This software is fast since the core algorithm is written in C. For very large data sets, a parallel version of DEXUS is provided in this package. DEXUS is a statistical model that is selected in a Bayesian framework by an EM algorithm. It does not need replicates to detect differentially expressed transcripts, since the replicates (or conditions) are estimated by the EM method for each transcript. The method provides an informative/non-informative value to extract differentially expressed transcripts at a desired significance level or power. classification, differential expression, gene expression, hapmap, quality control, rna-seq, sequencing, bio.tools is listed by: OMICtools
is listed by: bio.tools
is listed by: Debian
has parent organization: Bioconductor
PMID:24049071 Free, Available for download, Freely available biotools:dexus, OMICS_02024 http://www.bioconductor.org/packages/release/bioc/html/dexus.html SCR_001309 DEXUS - Identifying Differential Expression in RNA-Seq Studies with Unknown Conditions or without Replicates 2026-02-07 02:05:30 1
CisGenome
 
Resource Report
Resource Website
50+ mentions
CisGenome (RRID:SCR_001558) data analysis tool Integrated software tool for tiling array, ChIP-seq, genome and cis-regulatory element analysis. sequencing software, chip seq, downstream analysis, chip analysis, bio.tools is listed by: OMICtools
is listed by: bio.tools
is listed by: Debian
works with: TileMap
PMID:18978777 Free, Available for download, Freely available OMICS_00423, biotools:cisgenome https://bio.tools/cisgenome http://biogibbs.stanford.edu/~jihk/CisGenome/index.htm SCR_001558 CisGenome v2.0 2026-02-07 02:05:39 81
vsn
 
Resource Report
Resource Website
1+ mentions
vsn (RRID:SCR_001459) vsn software resource Software package that implements a method for normalizing microarray intensities, both between colours within array, and between arrays. The method uses a robust variant of the maximum-likelihood estimator for the stochastic model of microarray data described in the references. The model incorporates data calibration (a.k.a. normalization), a model for the dependence of the variance on the mean intensity, and a variance stabilizing data transformation. Differences between transformed intensities are analogous to normalized log-ratios. However, in contrast to the latter, their variance is independent of the mean, and they are usually more sensitive and specific in detecting differential transcription. microarray, preprocessing, bio.tools is listed by: OMICtools
is listed by: Debian
is listed by: bio.tools
has parent organization: Bioconductor
has parent organization: European Bioinformatics Institute
Free, Available for download, Freely available OMICS_01977, biotools:vsn https://bio.tools/vsn SCR_001459 vsn - Variance stabilization and calibration for microarray data 2026-02-07 02:05:32 5
CytoSPADE
 
Resource Report
Resource Website
1+ mentions
CytoSPADE (RRID:SCR_001457) software resource Cytoscape plugin that provides a high-performance implementation of an interface for the Spanning-tree Progression Analysis of Density-normalized Events (SPADE) algorithm for tree-based analysis and visualization of high-dimensional cytometry data. plugin, mac os x, unix/linux, windows, c++, java, r uses: Cytoscape
is listed by: OMICtools
has parent organization: Stanford University; Stanford; California
is a plug in for: Cytoscape
PMID:22782546 Free, Available for download, Freely available OMICS_05644 http://cytospade.org/ SCR_001457 CytoSPADE: Cytoscape-driven Spanning tree Progression of Density normalized Events, CytoSPADE Cytoscape Plugin for SPADE, Cytoscape-driven Spanning tree Progression of Density normalized Events 2026-02-07 02:05:38 2
BACContigEditor
 
Resource Report
Resource Website
BACContigEditor (RRID:SCR_001617) BACContigEditor software resource A simple sequence alignment editing tool, written in Java. matlab is listed by: OMICtools
has parent organization: SourceForge
Free, Available for download, Freely available OMICS_00875 SCR_001617 2026-02-07 02:05:34 0
Enriched Domain Detector
 
Resource Report
Resource Website
1+ mentions
Enriched Domain Detector (RRID:SCR_001693) EDD software resource A ChIP-seq peak caller for detection of megabase domains of enrichment. standalone software, unix/linux, mac os x is listed by: OMICtools PMID:24782521 Free, Available for download, Freely available OMICS_03964 SCR_001693 EDD - Enriched Domain Detector 2026-02-07 02:05:42 7
CNVrd2
 
Resource Report
Resource Website
1+ mentions
CNVrd2 (RRID:SCR_001723) software resource A software package that uses next-generation sequencing data to measure human gene copy number for multiple samples, indentify SNPs tagging copy number variants and detect copy number polymorphic genomic regions. standalone software, illumina, unix/linux, mac os x, windows, r, clustering., copy number variation, coverage, linkage disequilibrium, snp, sequencing is listed by: OMICtools
has parent organization: Bioconductor
PMID:23646200 Free, Available for download, Freely available OMICS_03924 http://www.bioconductor.org/packages/release/bioc/html/CNVrd2.html
https://github.com/hoangtn/CNVrd2
SCR_001723 CNVrd2: a read depth-based method to detect and genotype complex common copy number variants from next generation sequencing data 2026-02-07 02:05:42 5

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