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| Resource Name | Proper Citation | Abbreviations | Resource Type |
Description |
Keywords | Resource Relationships | |||||||||||||
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ABS: A Database of Annotated Regulatory Binding Sites From Orthologous Promoters Resource Report Resource Website 1+ mentions |
ABS: A Database of Annotated Regulatory Binding Sites From Orthologous Promoters (RRID:SCR_002276) | ABS | data or information resource, database | Public database of known binding sites identified in promoters of orthologous vertebrate genes that have been manually curated from bibliography. We have annotated 650 experimental binding sites from 68 transcription factors and 100 orthologous target genes in human, mouse, rat or chicken genome sequences. Computational predictions and promoter alignment information are also provided for each entry. For each gene, TFBSs conserved in orthologous sequences from at least two different species must be available. Promoter sequences as well as the original GenBank or RefSeq entries are additionally supplied in case of future identification conflicts. The final TSS annotation has been refined using the database dbTSS. Up to this release, 500 bps upstream the annotated transcription start site (TSS) according to REFSEQ annotations have been always extracted to form the collection of promoter sequences from human, mouse, rat and chicken. For each regulatory site, the position, the motif and the sequence in which the site is present are available in a simple format. Cross-references to EntrezGene, PubMed and RefSeq are also provided for each annotation. Apart from the experimental promoter annotations, predictions by popular collections of weight matrices are also provided for each promoter sequence. In addition, global and local alignments and graphical dotplots are also available. | gene, alignment, annotation, binding, computational, genome, nucleotide, ortholog, prediction, promoter, sequence, target, transcription, transcriptional factor, binding site, promoter sequence, protein motif, benchmark, transcription factor binding site, bio.tools |
is listed by: bio.tools is listed by: Debian is related to: IntegromeDB has parent organization: Center for Genomic Regulation; Barcelona; Spain |
European Union FP6 contract LSHG-CT-2003-503265 | PMID:16381947 | Acknowledgement requested, GNU General Public License, v2 | biotools:alggen, nif-0000-21006 | https://bio.tools/alggen | SCR_002276 | A database of Annotated regulatory Binding Sites from orthologous promoters | 2026-02-14 02:06:09 | 1 | ||||
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DrugBank Resource Report Resource Website 5000+ mentions |
DrugBank (RRID:SCR_002700) | DrugBank | data or information resource, database | Bioinformatics and cheminformatics database that combines detailed drug (i.e. chemical, pharmacological and pharmaceutical) data with comprehensive drug target (i.e. sequence, structure, and pathway) information. | drug, target, pathway, structure, pharmacology, drug class, chemical, pharmaceutical, drug target, sequence, reaction, interaction, protein, proteome, blast, data analysis service, small molecule-protein, small molecule, clinical medicine, pharmacy, medicine, pharmaceutical biotechnology, cheminformatics, FASEB list |
is used by: NIF Data Federation is used by: Open PHACTS is used by: In vivo - In silico Metabolite Database is used by: GEROprotectors is listed by: OMICtools is listed by: re3data.org is related to: ConsensusPathDB is related to: PharmGKB Ontology is related to: Allen Institute Neurowiki is related to: Coremine Medical is related to: MalaCards is related to: PSICQUIC Registry is related to: DrugPort is related to: Integrated Manually Extracted Annotation has parent organization: University of Alberta; Alberta; Canada |
Genome Alberta ; Genome Canada ; GenomeQuest Inc. ; Canadian Institutes of Health Research |
PMID:16381955 PMID:21059682 PMID:18048412 |
Free, Freely available | nif-0000-00417, OMICS_01580, r3d100010544 | https://doi.org/10.17616/R3V60M | SCR_002700 | 2026-02-14 02:06:11 | 5122 | |||||
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Evolutionary Lineage Inferred from Structural Analysis Resource Report Resource Website 1+ mentions |
Evolutionary Lineage Inferred from Structural Analysis (RRID:SCR_002343) | data or information resource, database | THIS RESOURCE IS NO LONGER IN SERVICE, documented August 23, 2016. ELISA is an online database that combines functional annotation with structure and sequence homology modeling to place proteins into sequence-structure-function neighborhoods. The atomic unit of the database is a set of sequences and structural templates that those sequences encode. A graph that is built from the structural comparison of these templates is called PDUG (protein domain universe graph). It introduces a method of functional inference through a probabilistic calculation done on an arbitrary set of PDUG nodes. Further, all PDUG structures are mapped onto all fully sequenced proteomes allowing an easy interface for evolutionary analysis and research into comparative proteomics. ELISA is the first database with applicability to evolutionary structural genomics explicitly in mind. | evolutionary, function, functional, analysis, annotation, atomic unit, calculation, comparative, domain, genomic, homology, modeling, place, probabilistic, protein, protein domain and protein classification databases, proteome, proteomic, sequence, structural, structure, template | has parent organization: Boston University; Massachusetts; USA | PMID:12952559 | THIS RESOURCE IS NO LONGER IN SERVICE | nif-0000-21141 | SCR_002343 | ELISA | 2026-02-14 02:06:09 | 1 | |||||||
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Database of Transcribed Sequences Resource Report Resource Website 10+ mentions |
Database of Transcribed Sequences (RRID:SCR_002334) | data or information resource, database | DoTS (Database Of Transcribed Sequences) is a human and mouse transcript index created from all publicly available transcript sequences. The input sequences are clustered and assembled to form the DoTS Consensus Transcripts that comprise the index. These transcripts are assigned stable identifiers of the form DT.123456 (and are often referred to as dots). The transcripts are in turn clustered to form putative DoTS Genes. These are assigned stable identifiers of the form DG.1234356. As of September 1, 2004, the DoTS annotation team has manually annotated 43,164 human and 78,054 mouse DoTS Transcripts (DTs), corresponding to 3,939 human and 7,752 mouse DoTS Genes (DGs). Use the manually annotated gene query to see the DoTS Transcripts that have been manually annotated. The focus of the DoTS project is integrating the various types of data (e.g., EST sequences, genomic sequence, expression data, functional annotation) in a structured manner which facilitates sophisticated queries that are otherwise not easy to perform. DoTS is built on the GUS Platform which includes a relational database that uses controlled vocabularies and ontologies to ensure that biologically meaningful queries can be posed in a uniform fashion. An easy way to start using the site is to search for DoTS Transcripts using an existing cDNA or mRNA sequence. Click on the BLAST tab at the top of the page and enter your sequence in the form provided. All the transcripts with significant sequence similarity to your query sequence will be displayed. Or use one of the provided queries to retrieve transcripts using a number of criteria. These queries are listed on the query page, which can also be reached by clicking on the tab marked query at the top of the page. Finally, the boolean query page allows these queries to be combined in a variety of ways. Sponsors: Funding provided by -NIH grant RO1-HG-01539-03 -DOE grant DE-FG02-00ER62893 | expression, functional, gene, annotation, biological, cdna, genomic, human, index, model organisms and comparative genomics databases, mouse, mrna, sequence, structure, transcribed, transcript | has parent organization: University of Pennsylvania; Philadelphia; USA | nif-0000-21125 | SCR_002334 | DoTs | 2026-02-14 02:05:47 | 15 | |||||||||
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MachiBase Resource Report Resource Website 1+ mentions |
MachiBase (RRID:SCR_003078) | MachiBase | data or information resource, database | Database for Drosophila melanogaster transcription profiling that allows users to search the Drosophilia genome, see sequence overviews, and look at various transcripts. The data were generated in conjunction with the recently developed high-throughput genome sequencer Illumina / Solexa using a newly developed 5'-end mRNA collection method. Approximately 25 million 25-27 nucleotide (nt) 5'-end mRNA tags from the embryos, larvae, young males, young females, old males, old females, and S2 (culture cell line) of D. melanogaster were collected. By arranging this vast amount of expression tag with other annotated data, they have built a one-stop service for Drosophila melanogaster transcription profiling. | transcription profiling, genome, sequence, transcript, mrna, promoter, gene expression, development, embryo, larvae, young, male, female, old, s2, culture, cell line, expressed sequence tag, solexa |
is listed by: OMICtools has parent organization: University of Tokyo; Tokyo; Japan |
PMID:18842623 | Free, Available for download, Freely available | OMICS_01878, nif-0000-03092 | SCR_003078 | 2026-02-14 02:06:10 | 1 | |||||||
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NCBI Protein Database Resource Report Resource Website 500+ mentions |
NCBI Protein Database (RRID:SCR_003257) | NCBI_GP, NCBI Protein, NCBI GP | data or information resource, database | Databases of protein sequences and 3D structures of proteins. Collection of sequences from several sources, including translations from annotated coding regions in GenBank, RefSeq and TPA, as well as records from SwissProt, PIR, PRF, and PDB. | amino acid sequence, nucleotide, dna sequence, protein, sequence, sequence data, structure, function, dna, nucleotide sequence, genomics, protein binding, gold standard |
is used by: NIF Data Federation is listed by: re3data.org is related to: AmiGO is related to: GenBank is related to: RefSeq is related to: TPA is related to: UniProtKB is related to: Protein Information Resource is related to: Protein Research Foundation is related to: Research Collaboratory for Structural Bioinformatics Protein Data Bank (RCSB PDB) is related to: BioExtract is related to: DIG IT - Database of Immunoglobulins and Integrated Tools has parent organization: NCBI |
Free, Freely available | SCR_017486, r3d100011331, nif-0000-03178 | http://www.ncbi.nlm.nih.gov/sites/entrez?db=protein https://doi.org/10.17616/R3JH0X |
SCR_003257 | Entrez Protein, Protein Database, NCBI Protein Database, Protein sequence database, Entrez Protein Database | 2026-02-14 02:05:43 | 963 | ||||||
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Mammalian Mitochondrial Genomics Database Resource Report Resource Website |
Mammalian Mitochondrial Genomics Database (RRID:SCR_003084) | MamMiBase | data or information resource, database | Database developed to assist the phylogeneticist user in retrieving individual gene sequence alignments for genes in complete mammalian mitochondrial genomes. Data retrieval in MamMiBase requires three stages. At the first stage, the user must select the mammalian species or group that (s)he wishes to study. In the second stage, the user will select the outgroup from a list that included all species selected in the first stage plus Xenopus laevis and Gallus gallus. Finally, at the third stage, the user will select individual mitochondrial gene alignments or a phylogenetic tree that (s)he wishes to download. | phylogeny, mitochondrial, genome, gene, sequence | has parent organization: National Laboratory for Scientific Computing; Rio de Janeiro; Brazil | Brazilian Ministry of Science Technology and Innovation ; National Research Council ; Rio de Janeiro Science Foundation ; FAPERJ |
PMID:15713730 | Free, Freely available | nif-0000-03099 | SCR_003084 | 2026-02-14 02:06:13 | 0 | ||||||
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TPA Resource Report Resource Website 1+ mentions |
TPA (RRID:SCR_003593) | TPA | data or information resource, database | Database designed to capture experimental or inferential results that support submitter-provided annotation for sequence data that the submitter did not directly determine but derived from GenBank primary data. Records are divided into two categories: * TPA:experimental: Annotation of sequence data is supported by peer-reviewed wet-lab experimental evidence. * TPA:inferential: Annotation of sequence data by inference (where the source molecule or its product(s) have not been the subject of direct experimentation) TPA records are retrieved through the Nucleotide Database and feature information on the sequence, how it was cataloged, and proper way to cite the sequence information. | gene, gene expression, nucleotide sequence, annotation, sequence |
is listed by: re3data.org is related to: GenBank is related to: NCBI Protein Database is related to: NCBI Nucleotide has parent organization: NCBI |
PMID:16901214 | nlx_157738, r3d100010506 | https://doi.org/10.17616/R3KS4H | SCR_003593 | Third Party Annotation, NCBI TPA, NCBI Third Party Annotation | 2026-02-14 02:05:44 | 4 | ||||||
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SYFPEITHI: A Database for MHC Ligands and Peptide Motifs Resource Report Resource Website 100+ mentions |
SYFPEITHI: A Database for MHC Ligands and Peptide Motifs (RRID:SCR_013182) | SYFPEITHI | data or information resource, database | SYFPEITHI is a database comprising more than 7000 peptide sequences known to bind class I and class II MHC molecules. The entries are compiled from published reports only. It contains a collection of MHC class I and class II ligands and peptide motifs of humans and other species, such as apes, cattle, chicken, and mouse, for example, and is continuously updated. Searches for MHC alleles, MHC motifs, natural ligands, T-cell epitopes, source proteins/organisms and references are possible. Hyperlinks to the EMBL and PubMed databases are included. In addition, ligand predictions are available for a number of MHC allelic products. The database is based on previous publications on T-cell epitopes and MHC ligands. It contains information on: -Peptide sequences -anchor positions -MHC specificity -source proteins, source organisms -publication references Since the number of motifs continuously increases, it was necessary to set up a database which facilitates the search for peptides and allows the prediction of T-cell epitopes. The prediction is based on published motifs (pool sequencing, natural ligands) and takes into consideration the amino acids in the anchor and auxiliary anchor positions, as well as other frequent amino acids. The score is calculated according to the following rules: The amino acids of a certain peptide are given a specific value depending on whether they are anchor, auxiliary anchor or preferred residue. Ideal anchors will be given 10 points, unusual anchors 6-8 points, auxiliary anchors 4-6 and preferred residues 1-4 points. Amino acids that are regarded as having a negative effect on the binding ability are given values between -1 and -3. Sponsors: SYFPEITHI is supported by DFG-Sonderforschungsbereich 685 and theEuropean Union: EU BIOMED CT95-1627, BIOTECH CT95-0263, and EU QLQ-CT-1999-00713. | epitope, allele, allelic, amino acid, ape, bind, cattle, chicken, class i, class ii, human, immunological database, ligand, mhc, molecule, motif, mouse, natural, organism, peptide, product, protein, sequence, specie, t-cell, bio.tools, FASEB list |
is listed by: bio.tools is listed by: Debian has parent organization: University of Tubingen; Tubingen; Germany |
nif-0000-21383, biotools:syfpeithi | https://bio.tools/syfpeithi | SCR_013182 | SYFPEITHI | 2026-02-14 02:06:48 | 258 | |||||||
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Therapeutically Relevant Multiple Pathways Database Resource Report Resource Website 1+ mentions |
Therapeutically Relevant Multiple Pathways Database (RRID:SCR_013471) | data or information resource, database | The Therapeutically Relevant Multiple Pathways Database is designed to provide information about such multiple pathways and related therapeutic targets described in the literatures, the targeted disease conditions, and the corresponding drugs/ligands directed at each of these targets. This database currently contains 11 entries of multiple pathways, 97 entries of individual pathways, 120 targets covering 72 disease conditions along with 120 sets of drugs directed at each of these targets. Each entry can be retrieved through multiple methods including multiple pathway name, individual pathway name and disease name. Additional information provided include protein name, synonyms, Swissprot AC number, species, gene name and location, protein sequence (AASEQ) and gene sequence (NTSEQ) as well as potential therapeutic implications while applicable. Cross-links to other databases are provided which include Genecard, GDB, Locuslink, NCBI, KEGG, OMIM, SwissProt to facilitate the access of more detailed information about various aspects of the particular target or non-target protein. Queries can be submitted by entering or selecting the required information in any one or combination of the fields in the form. User can specify full name or any part of the name in a text field, or choose one item from an selection field. Sponsors: TRMP is supported by the National University of Singapore. | drug, gene, condition, disease, intermolecular interactions and signaling pathways databases, ligand, literature, location, pathway, protein, sequence, specie, target, therapeutic, therapy | nif-0000-21402 | SCR_013471 | TRMP | 2026-02-14 02:06:50 | 2 | ||||||||||
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Codon and Codon-Pair Usage Tables Resource Report Resource Website 1+ mentions |
Codon and Codon-Pair Usage Tables (RRID:SCR_018504) | CoCoPUTs | data or information resource, database | Database includes genomic codon-pair and dinucleotide statistics of all organisms with sequenced genome. Facilitates genetic variation analyses and recombinant gene design. Derived from all available GenBank and RefSeq data. | Codon-pair, codon, nucleotide, gene, genomic codon pair, dinucleotide statistic, sequence, genetic variation, recombinant gene design, data |
is related to: GenBank is related to: RefSeq |
PMID:31029701 | Free, Freely available | SCR_018504 | 2026-02-14 02:06:33 | 5 | ||||||||
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Database of Antimicrobial Activity and Structure of Peptides Resource Report Resource Website 10+ mentions |
Database of Antimicrobial Activity and Structure of Peptides (RRID:SCR_016600) | DBAASP | data or information resource, database | Collection of manually curated data regarding structure and antimicrobial activity of natural and synthetic peptides. Provides the information and analytical resources to develop antimicrobial compounds with the high therapeutic index. | data, collection, structure, antimicrobial, activity, natural, synthetic, peptide, sequence | NIAID G2102; Shota Rustaveli National Science Foundation FR397718014; International Science and Technology Center |
PMID:26578581 PMID:27060142 |
Free, Freely available | SCR_016600 | DataBase of Antimicrobial Activity and Structure of Peptides, Database of Antimicrobial Activity and Structure of Peptides | 2026-02-14 02:06:31 | 42 | |||||||
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MACH 1.0 Resource Report Resource Website 50+ mentions |
MACH 1.0 (RRID:SCR_001759) | software application, data processing software, data analysis software, software resource | A Markov Chain based software tool for haplotyping, genotype imputation and disease association analysis that can resolve long haplotypes or infer missing genotypes in samples of unrelated individuals. | gene, genetic, genomic, haplotype, genotype, genomic analysis, imaging genomics, imputation, snp, gene, haplotyping, sequence |
is listed by: OMICtools is listed by: Genetic Analysis Software is listed by: NeuroImaging Tools and Resources Collaboratory (NITRC) is related to: Mach2dat has parent organization: University of Michigan; Ann Arbor; USA |
PMID:21058334 PMID:19715440 |
Free | nlx_154202, OMICS_00064 | SCR_001759 | MArkov Chain Haplotyper MINIMAC, MArkov Chain Haplotyping | 2026-02-15 09:18:10 | 58 | |||||||
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Protein Databank Fun Resource Report Resource Website 1+ mentions |
Protein Databank Fun (RRID:SCR_008226) | software application, data processing software, data analysis software, software resource | THIS RESOURCE IS NO LONGER IN SERVICE, documented August 23, 2016. PDBfun is a web server for structural and functional analysis of proteins at the residue level. pdbFun gives fast access to the whole Protein Data Bank (PDB) organized as a database of annotated residues. The available data (features) range from solvent exposure to ligand binding ability, location in a protein cavity, secondary structure, residue type, sequence functional pattern, protein domain and catalytic activity. PDBfun is an integrated web tool for querying the PDB at the residue level and for local structural comparison. It integrates knowledge on single residues in protein structures coming from other databases or calculated with available or in-house developed instruments for structural analysis. Each set of different annotations represents a feature. Features are listed in PDBfun main page in orange. Features can be used for building residues selections. | functional, 2d, ability, activity, analysis, binding, catalytic, cavity, chain, cleft, domain, ligand, location, motif, protein, protein structure databases, residue, secondary, sequence, size, solvent, structural, structure, surface | THIS RESOURCE IS NO LONGER IN SERVICE | nif-0000-21315 | SCR_008226 | PDBfun | 2026-02-15 09:19:45 | 2 | |||||||||
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duphold Resource Report Resource Website 1+ mentions |
duphold (RRID:SCR_016938) | software application, data processing software, data analysis software, software resource | Software tool to annotate structural variant calls with sequence depth information that can add or remove confidence to SV predicted to affect copy number. Indicates the presence of a rapid change in depth relative to the regions surrounding the breakpoints. Allows the run time to be nearly independent of the number of variants important for large, jointly called projects with many samples. Annotates structural variant predictions made from both short read and long read data. | annotate, structural, variation, call, sequence, depth, confidence, predict, copy, number, short, long, read, data | is listed by: OMICtools | Free, Available for download, Freely available | SCR_016938 | 2026-02-15 09:21:12 | 2 | ||||||||||
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TMHMM Server Resource Report Resource Website 1000+ mentions |
TMHMM Server (RRID:SCR_014935) | web application, software resource | Web application for the prediction of transmembrane helices in proteins using Hidden Markov Models. FASTA formatted sequences can be uploaded via file or copy-paste, and output can be formatted as extensive with graphics, extensive without graphics, or one line per protein. Submissions are limited to 10,000 sequences and 4,000,000 amino acids - each sequence is limited to no more than 8,000 amino acids. | sequence, amino acid, web application, transmembrane helices, hidden markov model, fasta | Open source | SCR_014935 | TMHMM Server v 2.0 | 2026-02-15 09:21:03 | 1872 | ||||||||||
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ProP Server Resource Report Resource Website 50+ mentions |
ProP Server (RRID:SCR_014936) | web application, software resource | Web application which predicts arginine and lysine propeptide cleavage sites in eukaryotic protein sequences using an ensemble of neural networks. Furin-specific prediction is the default. It is also possible to perform a general proprotein convertase prediction. | web application, prediction, arginine, lysine, cleavage, propeptide, eukaryotic, protein, sequence, bio.tools |
is listed by: Debian is listed by: bio.tools |
DOI:10.1093/protein/gzh013 | Open source | biotools:prop, BioTools:prop | https://bio.tools/prop https://bio.tools/prop https://bio.tools/prop |
SCR_014936 | ProP, ProP 1.0 Server, ProP 1.0 | 2026-02-15 09:21:13 | 75 | ||||||
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Composition Profiler Resource Report Resource Website 10+ mentions |
Composition Profiler (RRID:SCR_014630) | web application, software resource | Web tool for discovery and visualization of differences in amino acid composition. Two samples of amino acid sequences serve as input and a bar chart composed of twenty data points is output. | web tool, web application, amino acid, amino acid composition, sequence, bar chart, bio.tools |
is listed by: Debian is listed by: bio.tools |
PMID:17578581 | Source code available, Acknowledgement requested | biotools:composition_profiler | https://bio.tools/composition_profiler | SCR_014630 | 2026-02-15 09:20:57 | 32 | |||||||
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trimAl Resource Report Resource Website 500+ mentions |
trimAl (RRID:SCR_017334) | software application, data processing software, data analysis software, software resource | Software tool for automated removal of spurious sequences or poorly aligned regions from multiple sequence alignment. Software package for automated alignment trimming in large scale phylogenetic analyses. | removal, spurious, sequence, poorly, aligned, region, multiple, alignment, trimming, large, scale, phylogenetic, analysis, bio.tools |
is listed by: OMICtools is listed by: Debian is listed by: bio.tools |
FIS ; MEC |
PMID:19505945 | Free, Available for download, Freely available | biotools:trimal | https://vicfero.github.io/trimal/ https://bio.tools/trimal |
SCR_017334 | 2026-02-15 09:21:19 | 582 | ||||||
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PIRATE Resource Report Resource Website 10+ mentions |
PIRATE (RRID:SCR_017265) | software application, data processing software, data analysis software, software resource | Software pangenomics toolbox for clustering diverged orthologues in bacteria. Used to identify and classify orthologous gene families in bacterial pangenomes over wide range of sequence similarity thresholds. | Pangenome, clustering, genomics, bacteria, orthologue, gene, sequence, amino acid, nucleotide, dataset, bio.tools |
is listed by: Debian is listed by: bio.tools |
DOI:10.1101/598391 | Free, Available for download, Freely available | biotools:PIRAtE | https://bio.tools/PIRATE | SCR_017265 | Pangenome Iterative Refinement And Threshold Evaluation | 2026-02-15 09:22:01 | 18 |
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