Tools   Select Another Resource Report Type

http://cau.eagle-i.net/i/00000135-abea-80e6-ecf8-187780000000

In CCRTD, we provide excellent support for Cell Biology research and advanced cell visualization applications. We have complete facilities for cell growth, handling, and storage. Cell Culture Facility maintains Cell Storage Cryo Tanks with uninterruptable liquid nitrogen supply and two separate Cell Culture rooms fully equipped with eight temperature and CO2-controlled Cell Growth Incubators, two Biological Safety Cabinets, Fluorescence-Activated Cell Sorter (FACS), two late model Inverted Digitized Microscope (Zeiss), one of which is fluorescence-enabled and possesses Z-stacking and live cell imaging capabilities, automated Cell Counter (Nexcelom Bioscience), and refrigerated storage for media and cell culture reagents.

Proper citation: CAU CCRTD-Cell Biology (RRID:SCR_009691) Copy   

•   Source: SciCrunch Registry

http://eagle-i.itmat.upenn.edu/i/00000139-4506-110d-eb5b-b63c80000000

Core facility that provides the following services: Stem cell differentiation, Stem cell line propagation. The human embryonic stem cell/induced pluripotent Stem Cell (hESC/iPSC) Core generates control and patient-specific iPSC lines by cellular reprogramming using current technologies. The core has a training course in cell maintenance and growth, specialized differentiation protocols for disease modeling and drug screening, and quality-control reagents for the Children?s Hospital and University of Pennsylvania academic communities. The facility maintains five NIH-approved human ESC lines and has generated more than 60 disease-specific iPSC lines.

Proper citation: CHOP Human Embryonic stem cell/induced pluripotent stem cell Core (RRID:SCR_009727) Copy   

•   Source: SciCrunch Registry

http://harvard.eagle-i.net/i/0000012c-60a7-d769-c437-ff0b80000000

The BWH-BRI Antibody Core Facility provides high quality, purified monoclonal antibodies to the BWH research community. Because the antibodies are made in-house and require no shipping, they are available at a cost substantially lower than that of commercial vendors. Antibodies are of standardized quality and are available in two convenient aliquots: 500ugs and 10mgs. The Core maintains an inventory of commonly used antibodies, which allows orders to be filled quickly.

Proper citation: BWH-BRI Antibody Core Facility (RRID:SCR_009689) Copy   

•   Source: SciCrunch Registry

http://eagle-i.itmat.upenn.edu/i/00000138-7cbe-8ce9-fbab-3b8480000000

Core facility that provides the following services: Vascular laboratory services, Vascular laboratory service, Carotid intima medial thickness measurment (IMT), Vascular laboratory service, Brachial Artery Reactivity (BART), Echocardiographic laboratory services, Exercise physiology laboratory services, Vascular laboratory service, Continuous arterial spin-labeling perfusion magnetic resonance imaging. The Cardiovascular Core provides cardiac testing services for children. The Core provides the technical services and expertise to conduct the highest quality research, provides research tests in a cost-effective manner, and provides unparalleled training opportunities in clinical research for investigators, fellows, students and technicians.

Proper citation: CHOP CTRC Cardiovascular Imaging Core (RRID:SCR_009722) Copy   

•   Source: SciCrunch Registry

http://harvard.eagle-i.net/i/0000012a-2511-e97c-5617-794280000000

Core facility that provides the following services: ES cell transfection (electroporation), Thawing/expansion of targeted ES cells, Microinjection of ES cells into blastocysts, Microinjection of DNA constructs into egg pronuclei for generating transgenic mice, Microinjection of BAC DNAs, DNA injection and microdissection, Lentiviral transgenics service, Injection of induced pluripotent stem cells for testing totipotency, Tail biopsy service, Breeding services, Mouse manipulation consultation. The Brigham & Women''s Hospital Transgenic Core Facility provides services for generating transgenic and knockout mice. Established in 1992, the BWH Core Facility has been providing gene targeting and microinjection services using state-of-the-art facilities and equipment. Dr. Lina Du, formerly a plastic surgeon in Beijing and an expert in microvascular surgery, performs both blastocyst and pronuclear injections. She has over 15 years of experience in embryo manipulation and the generation transgenic mice. The Core Facility has all of the equipment necessary for generation of transgenic mice including a Nikon Diaphot microscope equipped with Nomarski Optics and Narishige micromanipulators for microinjections, Nikon surgical microscopes for egg isolation ad transfer, a sutter needle puller and a de Fonbrune microforge. The facility maintains mice necessary for egg donors, egg recipients, and vasectomized males. This is a non-profit facility and charges are based upon anticipated mouse costs, maintenance of mice and equipment, and purchase of necessary surgical supplies and chemicals. The ES cell culture service has been offered for 6 years. Our staff carries out electroporation of targeting vectors into ES cells and provides investigators with DNA to identify ES cells carrying the desired recombination events. Then they expand the appropriate ES Cells for microinjection into blastocysts by the BWH Transgenic Core.

Proper citation: BWH Transgenic Core Facility (RRID:SCR_009688) Copy   

•   Source: SciCrunch Registry

http://eagle-i.itmat.upenn.edu/i/00000139-4fa9-b5b5-eb5b-b63c80000000

Core facility that provides the following services: Development of assessment methods for pediatric psychological, neuropsychological, and psychiatric research, Intervention development and implementation. The Behavioral Neurosciences Core provides consultation and assistance to investigators regarding psychological, neuropsychological, and psychiatric components of research studies involving pediatric subjects. Together, the services provided by the Behavioral Neurosciences Core offer research infrastructure support across the entire process of research, from pre-design consultation to development and analysis of behavioral data, and across multiple domains of functioning and outcomes.

Proper citation: CHOP CTRC Behavioral Neurosciences Core (RRID:SCR_009721) Copy   

•   Source: SciCrunch Registry

http://harvard.eagle-i.net/i/0000012b-00c4-1614-db6e-7a3f80000000

Core facility that provides the following services: Magnetic resonance spectrometer training service, Magnetic Resonance Instrument Access. Welcome to the Magnetic Resonance Facility of the Department of Chemistry and Chemical Biology, Harvard University, in the Laukien-Purcell Instrumentation Center.

Proper citation: Harvard FAS Magnetic Resonance Laboratory (RRID:SCR_008476) Copy   

•   Source: SciCrunch Registry

http://harvard.eagle-i.net/i/0000012a-438e-1d98-3e3e-48fb80000000

Core facility that provides the following services: Sorting or analysis with operator service, Calcium flux measurements service, DNA analysis service, Cell sorting service.

This lab''s mission is to provide high standard cell sorting and analysis services to the research community at the Brigham and Women?s Hospital and the Longwood Medical area.

Proper citation: BWH Flow Cytometry Core Laboratory (RRID:SCR_009683) Copy   

•   Source: SciCrunch Registry

http://harvard.eagle-i.net/i/0000012c-654b-2967-c437-ff0b80000000

Core facility that provides the following services: Fluorescence in situ hybridization.

The CytoGenomics Core provides an invaluable technical resource to the investigators of the BWH, MGH, and affiliated institutions. Services are also available to external academic and commercial laboratories; these should contact us via our website for sample submission and pricing. Cytogenetic studies can provide insight into regions of the genome that are pathogenetic in various neoplasms leading to an understanding of the molecular pathways participating in the biology of cancer. It is appropriate to consider cytogenetics as a fundamental adjunct to a variety of investigations underway, including basic and clinical research. For example, a rather simple cytogenetic analysis of mouse ES cells to determine ploidy prior to injections into blastulas leads to a greater success rate in establishing founders for knock-out and knock-in experiments. The primary chromosomal assignment of a gene by a FISH experiment may lead to correlation of a disease with that gene. Other cytogenetic studies may be important in establishing a diagnosis for correlation with clinical outcome. The advent of molecular probes for FISH analysis has facilitated cytogenetic studies in the mouse, and other model organisms and this Core aggressively implements such technologies. In addition to state-of-the-art analyses for human samples, the BWH CytoGenomics Core also performs routine mouse karyotyping and a variety of other molecular cytogenetic analyses, services not easily obtainable elsewhere.

Proper citation: BWH CytoGenomics (RRID:SCR_009681) Copy   

•   Source: SciCrunch Registry

http://harvard.eagle-i.net/i/0000012c-64ed-0030-c437-ff0b80000000

Biostatistics support is available to investigators in the Brigham and Women''s and Harvard Medical research community for statistical consulting on issues such as study design and data analysis for manuscripts and grant applications. Resources are limited, so planning ahead is essential. The Biostatistics Consulting Service is part of the Biostatistics Core of the BWH Center for Clinical Investigation (CCI).

Proper citation: BWH Biostatistics Center (RRID:SCR_009680) Copy   

•   Source: SciCrunch Registry

http://harvard.eagle-i.net/i/0000012d-b966-5568-4882-b08d80000000

In recognition of the value of small animal imaging to the research community, Children''s Hospital Boston has committed to developing a state-of-the-art Small Animal Imaging Laboratory. The SAIL facility is located within the Department of Radiology''s Kresge Laboratory.

Proper citation: CHB Small Animal Imaging Core Laboratory (RRID:SCR_009719) Copy   

•   Source: SciCrunch Registry

http://harvard.eagle-i.net/i/0000012d-c2f2-d124-4882-b08d80000000

The radiopharmaceutical chemistry research program occupies two research laboratories in the Enders research building at Children''s: a radiopharmaceutical chemistry laboratory and a hot laboratory. A separate cell-culture laboratory is also available. The radiopharmaceutical chemistry laboratory contains four fume hoods, approximately 50 linear feet of bench space, and is set up to accommodate three postdoctoral researchers.

Proper citation: CHB Radiopharmaceutical Chemistry Laboratory (RRID:SCR_009718) Copy   

•   Source: SciCrunch Registry

http://www.med.upenn.edu/idom/drc/cores/cellbio.html

Core that gives support including experimental design, islet isolation, and performance of and training in an expansive range of assays for physiological and morphometric assessment of pancreatic islet function and growth. It contributes to the basic and translational research activities of the Institute of Diabetes, Obesity and Metabolism (IDOM) at the Perelman School of Medicine of the University of Pennsylvania. Its services include perform individual islet and single cell fluorescence imaging, respirometry with islet batches using a Seahorse Extracellular Flux Analyzer, perifusion coupled with respirometry, and closed respirometry experiments for our investigators.

Proper citation: University of Pennsylvania School of Medicine Penn Diabetes Research Center Pancreatic Islet Cell Biology Core Facility (RRID:SCR_008265) Copy   

•   Source: SciCrunch Registry

http://eagle-i.itmat.upenn.edu/i/00000139-4f55-f0f9-eb5b-b63c80000000

Core facility that provides the following services: Laser confocal microscope access. Penn Dental Medicine houses a Radiance 2100 laser confocal microscope available for use by researchers throughout the School as well as others inside and outside the University.

Proper citation: Penn Laser Confocal Microscope Core (RRID:SCR_009533) Copy   

•   Source: SciCrunch Registry

http://harvard.eagle-i.net/i/0000012e-3502-595e-550e-f59280000000

An Core facility

Proper citation: HSPH Organic Chemistry Laboratory (RRID:SCR_008280) Copy   

•   Source: SciCrunch Registry

http://harvard.eagle-i.net/i/00000137-e1a0-4fec-d807-77a880000000

The Weld Hill Growth Facilities consist of 12 individually controlled greenhouses and several types of Conviron growth chambers for precise control of growing conditions.

Proper citation: Arnold Arboretum of Harvard University: Weld Hill Growth Facilities (RRID:SCR_009649) Copy   

•   Source: SciCrunch Registry

http://www.itmat.upenn.edu/ctsa/acard/

A core facility in the Center for Pharmacoepidemiology Research and Training created to foster epidemiologic research into therapeutics, using large population-based automated claims databases (Medicaid/Medicare) and medical records databases (GPRD and THIN), and the FDA''s adverse event reporting system (FAERS) database. Goals: * Encourage investigators with diverse training to conduct studies focused on translational therapeutics and drug safety * Provide access to large databases that allow for rapid and cost-effective research on therapeutics and drug safety * Foster collaboration with CTSA sites outside of Penn who wish to use these databases for clinical research

Proper citation: Penn Automated Claims and Medical Record Databases (RRID:SCR_009643) Copy   

•   Source: SciCrunch Registry

http://harvard.eagle-i.net/i/0000012e-357f-dcfa-550e-f59280000000

Equipment access: All new users must be trained by the facility manager over two orientation sessions and be approved to use the equipment in the facility. All users must obtain the financial approval from their PI and financial manager. Please submit a PO number or the Harvard billing code prior to the first use of the facility.

Proper citation: HSPH Molecular Analysis Facility (RRID:SCR_008273) Copy   

•   Source: SciCrunch Registry

http://core.iddrc.org/molecular-genetics/

THIS RESOURCE IS NO LONGER IN SERVICE. Documented on October 8,2024. Core facility that provides the following services: DNA sequencing (standard) service, Taqman gene expression service, Taqman SNP genotyping, Digital PCR service, Genomic mapping facility standard service, DNA purification from blood and saliva, RNA purification service, Master 96-well plate sample preparation, Gene expression service, SNP genotyping service, Bioanalysis of RNA and DNA, Next-generation sequencing service, Sequenom SNP genotyping, SNP and qPCR 7900HT instrument access. The Molecular Genetics Core Facility (MGCF) is a non-profit core laboratory in the Program in Genomics and Genetics Division of Children''s Hospital Boston offering genomics services for academic research institutions. The majority of MGCF users are investigators from Children''s Hospital Boston and the surrounding Harvard affiliates, but the MGCF also serves laboratories throughout the entire United States. The MGCF is comprised of a compilation of smaller cores partially supported by private and federal funds. Funding is provided in part through The Intellectual and Developmental Disabilities Research Center, The Manton Center for Orphan Disease Research, The Wellstone Center for Muscular Dystrophy, and The Neuromuscular Disease Project of the Program in Genomics at Children''s Hospital Boston. The overall objective of the MGCF is to provide a location where researchers can have access to high quality, low cost genomic technology services and expertise in a timely, affordable manner. The services offered include DNA sequencing, Next-Gen sequencing, Affymetrix and Illumina whole-genome expression and genotyping microarray technology, microsatellite genotyping, high-throughput qPCR and SNP services on the Fluidigm Biomark System, multiplex SNP genotyping on the Sequenom MassARRAY, and sample extraction and banking. The MGCF also assists investigators with project design and collaborates on linkage and association study analysis.

Proper citation: CHB Molecular Genetics Core Facility (RRID:SCR_009715) Copy   

•   Source: SciCrunch Registry

http://harvard.eagle-i.net/i/00000130-0977-e10a-de5a-673e80000000

Core facility that provides the following services: Lipoprotein analysis, Biliary lipid concentrations analysis, Biliary particle analysis, Quantitative real-time PCR, Sequential ultracentrifugation for lipoproteins, Radiolabeling of lipoproteins, Fluorescence labeling of lipoproteins, Purification of biliary lipid aggregatesfrom model biles, Preparation of recombinant proteins, Protein identification from gel bands, Protein Identification from complex mixtures. The Molecular and Cellular Biochemistry Core is dedicated to providing HDDC investigators and their trainees with access to a variety of methods to determine the compositions of tissues, as well as their cellular and subcellular specimens. The Core Scientists offer a broad range of analyses and preparatory services including Proteomics. Importantly, the Core also provides training in the application of state-of-the-art techniques in molecular analysis of proteins, lipids and nucleic acids. The main Core laboratory is located at Brigham and Women?s Hospital (BWH) and the satellite Core laboratory is located at Children?s Hospital Boston (CHB). We perform a broad array of biochemical and analytical assays that are not typically available within laboratories of HDDC members. These have generally been adapted so that they may be performed in large numbers on microplates. These include quantification of lipids, mRNA and protein and a full array of mass spectroscopy services for protein analysis (and soon to be expanded for lipidomics). We also offer both analytical and preparatory separations by a variety of methods.

Proper citation: CHB Molecular and Cellular Biochemistry Core (RRID:SCR_009716) Copy   

•   Source: SciCrunch Registry