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SciCrunch Registry is a curated repository of scientific resources, with a focus on biomedical resources, including tools, databases, and core facilities - visit SciCrunch to register your resource.

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Resource Name Proper Citation Abbreviations Resource Type Description Keywords Resource Relationships Related Condition Funding Defining Citation Availability Website Status Alternate IDs Alternate URLs Old URLs Parent Organization Resource ID Synonyms Record Last Update Mentions Count
ContEst
 
Resource Report
Resource Website
1+ mentions
ContEst (RRID:SCR_000595) ContEst software resource THIS RESOURCE IS NO LONGER IN SERVICE. Documented on August 8,2025. A software tool (and method) for estimating the amount of cross-sample contamination in next generation sequencing data. java, contamination, next-generation sequencing, bio.tools is listed by: OMICtools
is listed by: bio.tools
is listed by: Debian
has parent organization: Broad Institute
PMID:21803805 THIS RESOURCE IS NO LONGER IN SERVICE OMICS_01038, biotools:contest https://bio.tools/contest SCR_000595 2026-02-14 01:59:49 6
FlipFlop
 
Resource Report
Resource Website
FlipFlop (RRID:SCR_000625) software resource Software that discovers which isoforms of a gene are expressed in a given sample together with their abundances, based on RNA-Seq read data. standalone software, unix/linux, mac os x, windows, r, rna-seq, bio.tools is listed by: OMICtools
is listed by: bio.tools
is listed by: Debian
has parent organization: Bioconductor
PMID:24813214 THIS RESOURCE IS NO LONGER IN SERVICE OMICS_04028, biotools:flipflop https://bio.tools/flipflop SCR_000625 flipflop - Fast lasso-based isoform prediction as a flow problem 2026-02-14 01:59:50 0
BLASR
 
Resource Report
Resource Website
10+ mentions
Discontinued
BLASR (RRID:SCR_000764) software resource THIS RESOURCE IS NO LONGER IN SERVICE. Documented on February 28,2023. C++ long-read aligner for PacBio reads., THIS RESOURCE IS NO LONGER IN SERVICE. Documented on September 16,2025. standalone software, c++, bio.tools is listed by: OMICtools
is listed by: bio.tools
is listed by: Debian
is related to: Proovread
PMID:22988817
DOI:10.1186/1471-2105-13-23
THIS RESOURCE IS NO LONGER IN SERVICE biotools:blasr, OMICS_05134 https://bio.tools/blasr
https://sources.debian.org/src/blasr/
SCR_000764 Basic Local Alignment with Successive Refinement, BLASR: The PacBio long read aligner 2026-02-14 01:59:49 15
GMcloser
 
Resource Report
Resource Website
1+ mentions
GMcloser (RRID:SCR_000646) GMcloser software resource Software that fills and closes the gaps present in scaffold assemblies, especially those generated by the de novo assembly of whole genomes with next-generation sequencing (NGS) reads. Unlike other gap-closing tools that use only NGS reads, GMcloser uses preassembled contig sets or long read sets as the sequences to close gaps and uses paired-end (PE) reads and a likelihood-based algorithm to improve the accuracy and efficiency of gap closure. The efficiency of gap closure can be increased by successive treatments with different contig sets. scaffolding, bio.tools is listed by: OMICtools
is listed by: bio.tools
is listed by: Debian
has parent organization: SourceForge
PMID:26261222 Free, Available for download, Freely available biotools:gmcloser, OMICS_00042 https://bio.tools/gmcloser SCR_000646 Gmcloser - Closing the gaps in scaffolds with preassembled contigs 2026-02-14 01:59:50 3
clipcrop
 
Resource Report
Resource Website
clipcrop (RRID:SCR_000678) software resource Software tool for detecting structural variations with single-base resolution using soft-clipping information from SAM files. structural variation, detecting structural variations, soft-clipping information, SAM files, bio.tools is listed by: OMICtools
is listed by: Debian
is listed by: bio.tools
PMID:22373054 Free, Available for download, Freely available biotools:clipcrop, OMICS_00310 https://bio.tools/clipcrop SCR_000678 ClipCrop 2026-02-14 01:59:48 0
TriageTools
 
Resource Report
Resource Website
TriageTools (RRID:SCR_000675) TriageTools software resource A collection of tools for partitioning raw data (fastq reads) from high-throughput sequencing projects. The tools are designed for basic data management as well for prioritizing analysis of certain subsets. matlab, java, bio.tools is listed by: OMICtools
is listed by: bio.tools
is listed by: Debian
has parent organization: SourceForge
PMID:23408855 Free, Available for download, Freely available biotools:triagetools, nlx_156740 https://bio.tools/triagetools SCR_000675 2026-02-14 01:59:48 0
Opera
 
Resource Report
Resource Website
1+ mentions
Opera (RRID:SCR_000665) software resource A sequence assembly software program that uses information from paired-end reads to optimally order and orient contigs assembled from shotgun-sequencing reads. sequence assembly, paired-end, orient contigs, shotgun-sequencing, shotgun, software program, bio.tools is listed by: OMICtools
is listed by: bio.tools
is listed by: Debian
has parent organization: SourceForge
PMID:27169502
PMID:21929371
Free, Available for download, Freely available biotools:opera, OMICS_00045 https://bio.tools/opera SCR_000665 OPERA-LG, Optimal Paired-End Read Assembler 2026-02-14 01:59:48 3
bsseq
 
Resource Report
Resource Website
1+ mentions
bsseq (RRID:SCR_001072) sequence analysis software, data processing software, data analysis software, software application, software resource R package with tools for analyzing and visualizing bisulfite sequencing data. bisulfite sequencing, analyze, r, sequence analysis software, data analysis software, bio.tools is listed by: OMICtools
is listed by: Debian
is listed by: bio.tools
has parent organization: Bioconductor
Free, Available for download, Freely available OMICS_01847, biotools:bsseq https://bio.tools/bsseq SCR_001072 bsseq - Analyze manage and store bisulfite sequencing data 2026-02-14 01:59:54 8
SplitSeek
 
Resource Report
Resource Website
1+ mentions
SplitSeek (RRID:SCR_001012) sequence analysis software, data processing software, data analysis software, software application, software resource THIS RESOURCE IS NO LONGER IN SERVICE, documented September 20, 2016. A program for de novo prediction of splice junctions in RNA-seq data. bioinformatics alignment, sequence analysis software, de novo, prediction, rna seq, rna, splice junction, bio.tools is listed by: OMICtools
is listed by: bio.tools
is listed by: Debian
PMID:20236510 THIS RESOURCE IS NO LONGER IN SERVICE biotools:splitseek, OMICS_01253 https://bio.tools/splitseek http://www.uppmax.uu.se/software/splitseek SCR_001012 2026-02-14 01:59:53 1
ASC
 
Resource Report
Resource Website
1+ mentions
ASC (RRID:SCR_001013) ASC software resource Borrows information across sequences to establish prior distribution of sample variation, so that biological variation can be accounted for even when replicates are not available. sample variation, rna, dna, biology, bio.tools is listed by: OMICtools
is listed by: bio.tools
is listed by: Debian
has parent organization: Brown University; Rhode Island; USA
biotools:sqn, OMICS_01298 https://bio.tools/sqn SCR_001013 2026-02-14 01:59:52 1
AutoAssemblyD
 
Resource Report
Resource Website
AutoAssemblyD (RRID:SCR_001087) sequence analysis software, data processing software, data analysis software, software application, software resource Software which performs local and remote genome assembly by several assemblers based on an XML Template which can replace the large command lines required by most assemblers. genome, genome assembly, xml, sequence analysis software, local genome assembly, remote genome assembly, bio.tools is listed by: OMICtools
is listed by: bio.tools
is listed by: Debian
has parent organization: SourceForge
PMID:24143057 Free, Available for download, Freely available biotools:autoassemblyd, OMICS_00874 https://bio.tools/autoassemblyd SCR_001087 2026-02-14 01:59:53 0
jmzML
 
Resource Report
Resource Website
1+ mentions
jmzML (RRID:SCR_001119) software resource A Java application programming interface (API) for the Proteomics Standards Initiative mzML data standard. standalone software, mac os x, unix/linux, windows, java, bio.tools is listed by: OMICtools
is listed by: bio.tools
is listed by: Debian
has parent organization: Google Code
PMID:20127693 Free, Available for download, Freely available biotools:jmzml, OMICS_03340 https://bio.tools/jmzml SCR_001119 2026-02-14 01:59:55 1
massiR
 
Resource Report
Resource Website
massiR (RRID:SCR_001157) software resource Software that predicts the sex of samples in gene expression microarray datasets. standalone software, mac os x, unix/linux, windows, r, classification, clustering, gene expression, microarray, quality control, bio.tools is listed by: OMICtools
is listed by: bio.tools
is listed by: Debian
has parent organization: Bioconductor
PMID:24659105 Free, Available for download, Freely available biotools:massir, OMICS_03638 https://bio.tools/massir SCR_001157 massiR: MicroArray Sample Sex Identifier, MicroArray Sample Sex Identifier 2026-02-14 01:59:56 0
Reaper - Demultiplexing trimming and filtering sequencing data
 
Resource Report
Resource Website
1+ mentions
Reaper - Demultiplexing trimming and filtering sequencing data (RRID:SCR_001144) Reaper software resource THIS RESOURCE IS NO LONGER IN SERVICE. Documented on September 23, 2022. Software program for demultiplexing, trimming and filtering short read sequencing data. c, alignment, sequence, demultiplex, trim, filter, bio.tools is listed by: OMICtools
is listed by: bio.tools
is listed by: Debian
has parent organization: European Bioinformatics Institute
THIS RESOURCE IS NO LONGER IN SERVICE biotools:reaper, OMICS_02157 https://bio.tools/reaper SCR_001144 2026-02-14 01:59:56 1
Skylign
 
Resource Report
Resource Website
10+ mentions
Skylign (RRID:SCR_001176) Skylign data analysis service, analysis service resource, production service resource, service resource, software resource A tool for creating logos representing both sequence alignments and profile hidden Markov models. The interactive logos enable scrolling, zooming, and inspection of underlying values. Skylign can avoid sampling bias in sequence alignments by down-weighting redundant sequences and by combining observed counts with informed priors. It also simplifies the representation of gap parameters, and can optionally scale letter heights based on alternate calculations of the conservation of a position. sequence alignment, profile, logo, bio.tools is listed by: OMICtools
is listed by: bio.tools
is listed by: Debian
has parent organization: Janelia Research
PMID:24410852 Creative Commons Attribution License, v3 Unported biotools:skylign, OMICS_02182 https://bio.tools/skylign SCR_001176 Skylign - Interactive logos for alignments and profile HMMs 2026-02-14 01:59:55 13
yaqcaffy
 
Resource Report
Resource Website
1+ mentions
yaqcaffy (RRID:SCR_001295) yaqcaffy software resource Software package for quality control of Affymetrix GeneChip expression data and reproducibility analysis of human whole genome chips with the MAQC reference datasets. microarray, one channel, quality control, report writing, affymetrix, gene expression, bio.tools is listed by: OMICtools
is listed by: Debian
is listed by: bio.tools
has parent organization: Bioconductor
Free, Available for download, Freely available BioTools:yaqcaffy, biotools:yaqcaffy, OMICS_02040 http://www.bioconductor.org/packages/release/bioc/html/yaqcaffy.html SCR_001295 yaqcaffy - Affymetrix expression data quality control and reproducibility analysis 2026-02-14 01:59:58 2
SplicePlot
 
Resource Report
Resource Website
SplicePlot (RRID:SCR_001172) SplicePlot software resource A software tool for visualizing alternative splicing and the effects of splicing quantitative trait loci (sQTLs) from RNA-seq data. It provides a simple command line interface for drawing sashimi plots, hive plots, and structure plots of alternative splicing events from .bam, .gtf, and .vcf files. visualization, alternative splicing, splicing quantitative trait loci, quantitative trait loci, rna-seq, hive plot, structure plot, sashmi plot, python, linux, mac os, bio.tools is listed by: OMICtools
is listed by: bio.tools
is listed by: Debian
has parent organization: Stanford University School of Medicine; California; USA
PMID:24363378 THIS RESOURCE IS NO LONGER IN SERVICE OMICS_02185, biotools:spliceplot https://bio.tools/spliceplot SCR_001172 SplicePlot: a tool for visualizing alternative splicing 2026-02-14 01:59:55 0
les
 
Resource Report
Resource Website
les (RRID:SCR_001291) les software resource THIS RESOURCE IS NO LONGER IN SERVICE. Documented on September 23,2022. Software package that estimates Loci of Enhanced Significance (LES) in tiling microarray data. These are regions of regulation such as found in differential transcription, CHiP-chip, or DNA modification analysis. The package provides a universal framework suitable for identifying differential effects in tiling microarray data sets, and is independent of the underlying statistics at the level of single probes. loci of enhanced significance, tiling microarray, tiling, microarray, chip-chip, dna modification, probe, dna methylation, differential expression, microarray, transcription, bio.tools is listed by: OMICtools
is listed by: Debian
is listed by: bio.tools
has parent organization: Bioconductor
THIS RESOURCE IS NO LONGER IN SERVICE biotools:les, OMICS_02045 https://bioconductor.org/packages/les/
https://bio.tools/les
SCR_001291 les package: Identifying Differential Effects in Tiling Microarray Data, Loci of Enhanced Significance 2026-02-14 01:59:57 0
sim4cc
 
Resource Report
Resource Website
sim4cc (RRID:SCR_001204) data processing software, alignment software, software application, software resource, image analysis software Software tool as cross species spliced alignment program.Heuristic sequence alignment tool for comparing cDNA sequence with genomic sequence containing homolog of gene in another species. Cross species spliced alignment, unix, sequence alignment, cdna sequence, genomic sequence, homolog, gene, splice, bio.tools is listed by: OMICtools
is listed by: Debian
is listed by: bio.tools
has parent organization: Johns Hopkins University; Maryland; USA
NSF CLS20163A;
Sloan Research Fellowship ;
NLM R01 LM006845
PMID:19429899 Free, Available for download, Freely available biotools:sim4cc, OMICS_02145 https://bio.tools/sim4cc SCR_001204 2026-02-14 01:59:57 0
QualiMap
 
Resource Report
Resource Website
10+ mentions
QualiMap (RRID:SCR_001209) QualiMap software resource Software application written in Java and R that provides both a Graphical User Inteface (GUI) and a command-line interface to facilitate the quality control of alignment sequencing data. It examines sequencing alignment data in SAM / BAM files according to the features of the mapped reads and provides an overall view of the data that helps to the detect biases in the sequencing and/or mapping of the data and eases decision-making for further analysis. next-generation sequencing, alignment, linux, macos, windows, quality control, sam, bam, bio.tools is listed by: OMICtools
is listed by: bio.tools
is listed by: Debian
has parent organization: Principe Felipe Research Centre; Valencia; Spain
Spanish Ministry of Economy and Competitiveness BIO2009-10799;
EU funded program ERA-NET PathoGenoMics BIO2008-05266-E
PMID:22914218
DOI:10.1093/bioinformatics/bts503
Free, Available for download, Freely available OMICS_02133, biotools:qualimap https://bio.tools/qualimap https://sources.debian.org/src/qualimap/ SCR_001209 QualiMap - Evaluating next generation sequencing alignment data 2026-02-14 01:59:58 47

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