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http://www.scienceexchange.com/facilities/cell-culture-and-cytogenetics-facility-pitt

The Cell Culture and Cytogenetics Facility carries out classical and molecular cytogenetic analyses. These studies include karyotyping, special staining and banding procedures, and fluorescence in situ hybridization (FISH). This analysis can be performed on cells from blood or tissue specimens from humans or experimental animals, cultured cells, and/or fresh, frozen, or paraffin-embedded tumor biopsies. This approach can be used to characterize the karyotype of cells; map the location of new genes, virus, or transgene insertions; monitor established cell lines to rule out interspecies cell culture contamination or other changes during cell culture; ensure the fidelity of embryonic stem cells prior to production of knockout mice; determine the pattern of chromosomal gains and losses; and enumerate copy numbers of chromosomes or cancer-related genes. The Cell Culture and Cytogenetics Facility provides comprehensive state-of-the-art cytogenetics services ranging from assisting investigators with study design, performing cell culture, preparing probes, carrying out and interpreting classical and molecular cytogenetic analyses, and assisting in manuscript preparation. The laboratory includes equipment for cell culture, cryopreservation, cytogenetic harvests, cytogenetic analysis of human and other mammalian cells, FISH, molecular genetic procedures requisite for FISH, including polymerase chain reaction (PCR) amplification, fluorescence and light microscopy, darkroom for standard photomicrography and printing as well as digital imaging and printing to laser or dye sublimation printers.

Proper citation: University of Pittsburgh Cell Culture and Cytogenetics Facility (RRID:SCR_012651) Copy   

•   Source: SciCrunch Registry

http://www.scienceexchange.com/facilities/neurotransgenic-laboratory-duke

THIS RESOURCE IS NO LONGER IN SERVICE. Documented on May 15,2024. Neurotransgenic Laboratory (NTL) at Duke University conducts technology development research and provides services, tools, and training towards the genetic analysis of the nervous system. Such tools include viruses for the precise stereotactical application of transgenes, plasmids and BACs for the generation of transgenic animals, genetically modified embryonic and induced pluripotent stem cells for differentiation and transplantation studies as well as for the generation of genetically modified animals.

Proper citation: Duke Neurotransgenic Laboratory (RRID:SCR_012496) Copy   

•   Source: SciCrunch Registry

https://systemsbiology.columbia.edu/genome-center

Core sells sequencing data and bioinformatic analytics services to the scientific community. Core aims to permit the development of research on sequencing protocols and encourage collaboration with clinicians to develop the next generation genomic DNA testing.

Proper citation: JP Sulzberger Columbia Genome Center (RRID:SCR_012650) Copy   

•   Source: SciCrunch Registry

https://www.cores.emory.edu/rbc/

One of the Emory Integrated Core Facilities (EICF), is supported by Emory University School of Medicine and the Georgia Clinical and Translational Science Alliance. We plan, execute, and analyze behavioral experiments examining activity, arousal, coordinated movement, learning and memory, anxiety, depression, seizure susceptibility, reward/reinforcement, and aggression in mice and rats.

Proper citation: Emory University Rodent Behavioral Core (RRID:SCR_012499) Copy   

•   Source: SciCrunch Registry

http://www.scienceexchange.com/facilities/baker-mountain-research-corporation

We are a not-for-profit scientific research corporation founded in 2010. The mission of the Baker Mountain Research Corporation has three complementary aspects: to advance scientific knowledge, to develop science-based solutions to local and global challenges, and to foster scientific education. A particular challenge we seek to address is the lack of scientific career and educational opportunities in our region. We work to build an interdisciplinary community that facilitates synthetic and analytic exploration, mentorship, sharing of experiences and which provides fair financial support.

Proper citation: Baker Mountain Research Corporation (RRID:SCR_012531) Copy   

•   Source: SciCrunch Registry

http://bioinformatics.hms.harvard.edu/

Core facility that offers consultations on basic questions in research computing, bioinformatics and computational biology during the initial stages of study design and grant proposals as well as for ongoing, funded studies requiring external expertise. Core has experience in large-scale data management, database design and software development. Staff members can provide assistance in quality assurance and analysis of gene expression arrays, genome-wide SNP arrays, CNV studies and different aspects of second-generation sequencing technologies such as ChIP-seq, RNA-Seq or resequencing efforts. Services also include provision of external information generated from public database, data curation and assistance on choosing the right data format and annotation standard to ensure best practices in data management and submission are being maintained.

Proper citation: Harvard Chan Bioinformatics Core (RRID:SCR_012655) Copy   

•   Source: SciCrunch Registry

http://www.scienceexchange.com/facilities/agcenter-biotechnology-laboratory-lsu

The LSU AgCenter Biotechnology Laboratory (ABL) is a core facility that provides basic and applied research expertise to support researchers in the LSU system as well as those in other academic institutions and industry. The ABL was formed in 1998 to provide support to faculty in performing biomolecular research. In 2010, the ABL was merged with the Protein Facility in LSU''''s College of Basic Sciences. Today, the ABL consists of three units: the Protein Facility, the Plant Transformation Facility and the Animal Cell Culture Facility.

Proper citation: LSU AgCenter Biotechnology Laboratory (RRID:SCR_012536) Copy   

•   Source: SciCrunch Registry

https://www.unmc.edu/vcr/cores/vcr-cores/mspcf/index.html

MSPCF maintains and uses equipment for protein separation and imaging, as well as for sample preparation for mass spectrometry analysis. Offers range of bioinformatics tools for data mining and evaluation. Services include Protein Identification, Protein Interactome Analysis, Protein Post-translational Modifications, Quantitative Mass Spectrometry, Molecular Weight determination.

Proper citation: University of Nebraska Medical Center Mass Spectrometry and Proteomics Core Facility (RRID:SCR_012539) Copy   

•   Source: SciCrunch Registry

http://www.scienceexchange.com/facilities/farooq-laboratory-of-macromolecular-biophysics-miami

Our laboratory applies a diverse array of biophysical techniques to study macromolecular interactions at hydrodynamic, thermodynamic, kinetic and structural level in the context of key signaling circuitry pertinent to cell growth and differentiation, cell survival and motility, cell cycle regulation, apoptosis and cancer. Our laboratory provides services in regards to the study of proteins, protein-protein and protein-ligand interactions using the following tools: - Isothermal Titration Calorimetry - Differential Scanning Calorimetry - Pressure Perturbation Calorimetry - Static Light Scattering - Dynamic Light Scattering - Stop-Flow Spectroscopy - Circular Dichroism - Molecular Modeling - Molecular Dynamics Please contact us for pricing and quotation.

Proper citation: UM Miller School of Medicine Farooq Laboratory of Macromolecular Biophysics (RRID:SCR_012662) Copy   

•   Source: SciCrunch Registry

http://www.scienceexchange.com/facilities/gvk-bio-chemistry-group

GVK Biosciences has expertise in small molecule synthesis from milligrams to kilo gram scale. Our Chemistry team serves diverse customer requirements from custom synthesis to scale-up through discovery chemistry. Customers can avail these services on a stand-alone or integrated services basis. Advantages of working with GVK Biosciences include: * No Conflict model: GVK BIO has no internal programs. * The IP /Confidentiality of Customers is well protected * Proven ability to Scale from mg to kg level at one location * On-line project tracking * E-Note book reporting (Optional) * Chemistry complemented by expert services in Biology and Computational Chemistry * The largest SAR manually curated database with 4 million compounds available * Multiple research sites across India * Comprehensive technical team with relevant Pharmaceutical, Biopharmaceutical, and Academic experiences. Highly qualified and experienced team * State of the art Analytical instrumentation with experienced analytical research scientists

Proper citation: GVK BIO Chemistry Group (RRID:SCR_012542) Copy   

•   Source: SciCrunch Registry

http://www.scienceexchange.com/facilities/cell-and-cell-products-fermentation-facility

Since its inception in 1951, the fermentation facility''s goal has been to provide affordable fermentation services to a highly diverse client base. Completely renovated in 2011 the fermentation facility, which meets BL2-LS containment requirements, is comprised of four contiguous operation units: -Material Preparation Laboratory -Fermentation In-Process -Computer Control -Product Recovery Room Bio-reactor working capacities range from 10 to 800 liters. All systems are computer controlled with algorithm-based cascade-capable PID programming. In the recovery room, downstream processing includes: -Centrifugation -Filtration -Micro and Ultra-filtration -Cell Disruption With the advantage of having the world''s pharmaceutical industry in its backyard, a productive climate of industrial liaison has been the historical legacy of the facility. Many former facility students and graduates hold positions within the industry. www.waksman.rutgers.edu/fermentation/home

Proper citation: Rutgers Cell and Cell Products Fermentation Facility (RRID:SCR_012729) Copy   

•   Source: SciCrunch Registry

http://www.scienceexchange.com/facilities/bio-fabrication

The ANFF provides leading-edge research capability and supports excellence in science. The capability provided by ANFF enables users to process hard materials (metals, composites and ceramics) and soft materials (polymers and polymer-biological moieties) and transform these into structures that have application in sensors, medical devices, nanophotonics and nanoelectronics. It has a strong emphasis on service provision to the research community. ANFF seeks to enhance national and international collaborations and enable world-class-research.

Proper citation: ANFF Bio Fabrication (RRID:SCR_012691) Copy   

•   Source: SciCrunch Registry

http://www.scienceexchange.com/facilities/materials-synthesis-and-macro-fabrication

The ANFF provides leading-edge research capability and supports excellence in science. The capability provided by ANFF enables users to process hard materials (metals, composites and ceramics) and soft materials (polymers and polymer-biological moieties) and transform these into structures that have application in sensors, medical devices, nanophotonics and nanoelectronics. It has a strong emphasis on service provision to the research community. ANFF seeks to enhance national and international collaborations and enable world-class-research.

Proper citation: ANFF Materials Synthesis and Macro Fabrication (RRID:SCR_012690) Copy   

•   Source: SciCrunch Registry

http://www.scienceexchange.com/facilities/photonics

THIS RESOURCE IS NO LONGER IN SERVICE. Documented on May 2,2024. ANFF provides leading-edge research capability and supports excellence in science. The capability provided by ANFF enables users to process hard materials (metals, composites and ceramics) and soft materials (polymers and polymer-biological moieties) and transform these into structures that have application in sensors, medical devices, nanophotonics and nanoelectronics. It has a strong emphasis on service provision to the research community. ANFF seeks to enhance national and international collaborations and enable world-class-research.

Proper citation: ANFF Photonics (RRID:SCR_012693) Copy   

•   Source: SciCrunch Registry

http://www.scienceexchange.com/facilities/cancer-research-informatics-core-cric-usc

Over the last 10 years the CRIC team has developed a set of software tools and applications to support the research activities of USC investigators. CRIC provides tools for data collection, migration, reporting, customized survey creation, and web-based data capture & reporting. CRIC has also developed and supported databases for laboratory data management, multi-center clinical trials coordination, epidemiologic & prevention studies as well as disease specific studies.

Proper citation: USC Cancer Research Informatics Core (RRID:SCR_012697) Copy   

•   Source: SciCrunch Registry

http://flowcytometry.sysbio.med.harvard.edu/

Core facility that provides the following services: Sorting and analysis services. The facility houses two state-of-the-art BD analyzers with high-throughput capability, a Stratedigm benchtop analyzer, a high-speed BD cell sorter, and both Mac and PC workstations for data analysis. Sorting services are offered through the facility, as well as instrument and software training.

Proper citation: HMS Systems Biology Flow Cytometry Facility (RRID:SCR_012696) Copy   

•   Source: SciCrunch Registry

http://www.scienceexchange.com/facilities/circulating-tumor-cells-ctc-core-facility-bcm

The CTC Core is devoted to the biology and enumeration of CTC in metastatic cancers. The Veridex CellSearch?? CTC Test is used to measure Circulating Tumor Cells (CTC) cells in blood samples from cancer patients. The technology can also be used to measure Circulating Endothelial Cells (CEC) in blood, as indicators of other vascular damage-associated diseases such as diabetes.

Proper citation: BCM Circulating Tumor Cells Core Facility (RRID:SCR_012698) Copy   

•   Source: SciCrunch Registry

http://www.scienceexchange.com/facilities/nutrient-and-phytochemical-analytics-shared-resource-npasr

THIS RESOURCE IS NO LONGER IN SERVICE. Documented in May 14,2024. Nutrient and Phytochemical Analytic Shared Resource (NPASR) provides expert bioanalytical method development and quantitative analysis. The NPASR will support development of methods and techniques to quantitatively determine nutrients and phytochemicals in foodstuffs as well as identification of these compounds and respective metabolites in biological samples from both human clinical trials and animal model investigations. The NPASR personnel are specialists in the field of analytical chemistry, concentrating their expertise in examining the bioavailability, metabolism and physiological significance of carotenoids, isothiocyanates, isoflavones and other phytochemicals. NPASR is capable of developing analytical methods for a Good Laboratory Practice (GLP) environment. Primary goals of NPASR are to provide investigators with expert, leading-edge bioanalytical method development and quantitative analysis of nutrients and phytochemicals in foodstuffs and their metabolites in biological samples and an enhanced understanding of the role of dietary compounds in cancer prevention and control.

Proper citation: OSU Nutrient and Phytochemical Analytics Shared Resource (RRID:SCR_012701) Copy   

•   Source: SciCrunch Registry

http://www.scienceexchange.com/facilities/bioprocess-scale-up-facility

The Bioprocess Scale-Up Facility (BSF) is the Biotechnology Research and Education Program''''s modern bioprocessing laboratory dedicated to the development and scale-up of biotechnology products and processes. With over 1000 fermentations conducted since 1998 alone, the BSF has accelerated the R&D of local biotechnology leaders such as Human Genome Sciences, NIH and MedImmune, as well as growing Maryland start-ups such as Martek Biosciences and Digene Corporation. The BSF''''s capabilities include fermentation, purification, product analysis and solving challenging problems such as biopolymers, turbulence and multiphase fluid dynamics, biosensors, process analysis and control, and both metabolic and biochemical engineering. BSF is a unique facility in Maryland not restricted by current good manufacturing practices (cGMP) requirements, and production processes are directly transferable to partners operating under cGMPs (required for FDA-approved clinical trials), such as Cambrex Inc. and the Walter Reed Army Institute of Research. The BSF enables small manufacturing companies to offer extended capabilities to major pharmaceutical (Big Pharma) companies out-of-state. The Biopharmaceutical Advancement Facility (BAF) specializes in the development of cell culture-based biopharmaceutical products. BAF is part of the Biotechnology Research and Education Program and a companion to the Bioprocess Scale-Up Facility in the Maryland Technology Enterprise Institute (Mtech) at the University of Maryland. The facility''''s staff members offer extensive expertise in addressing challenging problems with the advancement of anchorage-dependent or suspension-adapted cell lines. The facility is not restricted by current good manufacturing practices (cGMPs); however, production processes are directly transferable to partners operating under cGMPs.

Proper citation: UMD Bioprocess Scale-Up Facility (RRID:SCR_012703) Copy   

•   Source: SciCrunch Registry

http://www.scienceexchange.com/facilities/advanced-imaging-core-aic-uchicago

The Center''''s Advanced Imaging Core (AIC) features state-of-the-art core technologies available on a fee for service basis.

Proper citation: UChicago Advanced Imaging Core (RRID:SCR_012704) Copy   

•   Source: SciCrunch Registry