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SciCrunch Registry is a curated repository of scientific resources, with a focus on biomedical resources, including tools, databases, and core facilities - visit SciCrunch to register your resource.
https://nyonrc.cumc.columbia.edu/content/molecular-biologymolecular-genetics-core
Core whose goal is to assist investigators in applying the tools and technologies of molecular genetics and genomics to elucidate the molecular-genetic bases of obesity and its comorbidities. Its services include consultation on study design, analysis, and applicable molecular biological techniques and developing and making research tools and reagents.
Proper citation: New York Obesity Nutrition Research Center Molecular Biology and Molecular Genetics Core (RRID:SCR_015436) Copy
http://depts.washington.edu/cfrtc/microbiology/
Core facility which provides tools, reagents, and training for microbiological researchers investigating cystic fibrosis. They specifically provide resources for research in anti-bacterial therapies,
Proper citation: Cystic Fibrosis Center - University of Washington Microbiology Core (RRID:SCR_015403) Copy
http://depts.washington.edu/uwnorc/core-facilities/adipose-tissue-and-obesity-core/
Core that provides affiliated investigators with assistance for in vivo and in vitro studies in both subcutaneous and visceral human adipose tissue. Body and liver fat measurement by DXA and MRI are also provided, as is support for translational studies that assist investigators in the design conduct of clinical obesity research.
Proper citation: University of Washington Nutrition and Obesity Research Center Adipose Tissue and Obesity Core (RRID:SCR_015481) Copy
http://depts.washington.edu/cfrtc/genomics/
Core provides genomics-based tools, data management and analysis tools, and creates platforms that integrate data from the Clinical and Immunology Cores for human samples and bacterial isolates. Services include consultation and experimental design assistance for using new-generation sequencing technology, data analysis, bioinformatic support, data access and storage, high throughput and new-generation whole-genome sequencing, and RNA-seq analysis of transcriptomes.
Proper citation: University of Washington Genomics Core Cystic Fibrosis Research Translation Center and Research Development Program (RRID:SCR_015404) Copy
http://www.med.upenn.edu/gtp/immunology.shtml
Core facility which provides a variety of assay services to evaluate cell-mediated and humoral responses to in animal models of gene therapies.
Proper citation: University of Pennsylvania Center for Molecular Therapy for Cystic Fibrosis Immunology Core (RRID:SCR_015409) Copy
http://www.mmpc.org/shared/showCenterCore.aspx?id=48
Core which provides a complete range of microvascular phenotyping of murine models of diabetes, obesity and metabolic disease, including validated, reproducible and standardized phenotyping of the three major microvascular complications: diabetic polyneuropathy, nephropathy and retinopathy.
Proper citation: MMPC-University of Michigan Medical School Microvascular Complications Core (RRID:SCR_015376) Copy
https://labnodes.vanderbilt.edu/resource/view/id/10810/community_id/1418
Core whose services include determining the components of energy balance with high precision and time resolution, providing robust imaging technology to monitor the dynamics of cellular process, and providing innovative mouse bariatric surgery models with application to basic and translational research.
Proper citation: MMPC-Vanderbilt University School of Medicine Metabolic Regulation Core (RRID:SCR_015377) Copy
https://medicine.uiowa.edu/genetherapy/research-cores/cells-and-tissue-core
Core that provides centralized access to non-cystic fibrosis and cystic fibrosis tissue specimens and airway cells used for model systems to assess gene transfer to the airway and pathophysiology in cystic fibrosis.
Proper citation: University of Iowa Center for Gene Therapy Cell Tissue Core (RRID:SCR_015410) Copy
https://nyonrc.cumc.columbia.edu/content/animal-phenotyping-core
Core that allows investigators to efficiently and cost effectively define the phenotypes of small rodents in ways that are relevant to the study of obesity, nutrition, and metabolism. Its services range from whole animal measurements of body composition and energy utilization, to ex vivo measurements of substrate fluxes, to histological analyses of adipose tissue.
Proper citation: New York Obesity Nutrition Research Center Animal Phenotyping Core (RRID:SCR_015414) Copy
http://umassmed.edu/umpc/animal/humanized-mouse-core/
Core which provides humanized mice that enable clinically relevant in vivo studies of human cells, tissues, and immune system without putting patients at risk and expert in vivo functional analysis of transplanted human islets and stem cell-derived b-cells in immunodeficient mice that are highly valuable to the mouse research community.
Proper citation: MMPC-University of Massachusetts Medical School Humanized Mouse Cell Transplantation and Assessment Core (RRID:SCR_015372) Copy
http://www.med.unc.edu/cgibd/cores/biostatistics
Core facility that provides comprehensive statistical and data management services. Its statistical analysis services include study design, power and sample size analysis, randomization, statistical programming, consultation and the development of analysis plans, graphs, figures and reports.
Proper citation: University of North Carolina Center for Gastrointestinal Biology and Disease Biostatistics and Data Management Core (RRID:SCR_015616) Copy
http://www.med.unc.edu/cgibd/cores/histology
Core facility that provides a full range of histology services, encompassing routine and specialized grossing, tissue processing, paraffin embedding, microtomy, H&E and special staining, and immunohistochemistry. It also offers image analysis and consultations to CGIBD members and non-members.
Proper citation: University of North Carolina Center for Gastrointestinal Biology and Disease Histology Core (RRID:SCR_015614) Copy
http://www.med.upenn.edu/molecular/core_morphology.shtml
Core facility that provides histological services, equipment usage, and technical expertise to digestive and liver research projects.
Proper citation: University of Pennsylvania Center for Molecular Studies in Digestive and Liver Diseases Molecular Pathology and Imaging Core (RRID:SCR_015618) Copy
http://www.med.upenn.edu/molecular/core_molecular.shtml
Core facility that provides services that will enhance the analysis of both host and microbial biological processes as well as facilitate translation into the clinical arena via human subject research.
Proper citation: University of Pennsylvania Center for Molecular Studies in Digestive and Liver Diseases Host-Microbial Analytic and Repository Core (RRID:SCR_015620) Copy
http://vmmpc.org/body-weight-regulation-core/
Core facility for MMPC Vanderbilt University School of Medicine for studying impact of genetic, surgical, dietary and pharmacologic manipulations on body weight regulation. Core provides measurement of food intake, energy expenditure, and behavioral factors. Energy balance studies are performed in mouse home cage to minimize stress. Mitochondrial function is assessed on permeabilized tissues, isolated cells, or isolated mitochondria. Mouse models of bariatric surgery have been developed and studied extensively.
Proper citation: MMPC Vanderbilt University School of Medicine Body Weight Regulation Core (RRID:SCR_015905) Copy
https://sdrc.stanford.edu/sdrc-research-cores/dctc/home/
With the following services from the Diabetes Clinical and Translational Core (DCTC), members will receive training in biospecimen preservation, study design, data analysis, data management, use of statistical software and clinical trial conduct.
Proper citation: Stanford Diabetes Research Center Diabetes Clinical and Translational Core (RRID:SCR_016212) Copy
https://sdrc.stanford.edu/sdrc-research-cores/dimc/home/
Core facility that provides immune monitoring assays at the RNA, protein, and cellular level, as well as archiving, reporting, and data mining support for clinical and translational studies related to Diabetes. The DIMC is a specialized subcore of the Human Immune Monitoring Center (HIMC) at Stanford.
Proper citation: Stanford Diabetes Research Center Diabetes Immune Monitoring Core (RRID:SCR_016210) Copy
https://sdrc.stanford.edu/sdrc-research-cores/sirc/home/
Core facility whose services include: Islet Isolation, Islet transplantation, Islet Culture, Islet Perifusion & Islet Hormone Assays. The SIRC is supported by the Stanford Diabetes Research Center (SDRC).
Proper citation: Stanford Diabetes Research Center Stanford Islet Research Core (RRID:SCR_016211) Copy
https://ncdiabetesresearch.org/acsmc
Core to leverage data, patient populations and investigators at each NCDRC institution, including accessing expertise and resources of regional Clinical and Translational Science Institute hubs (Duke, UNC, and Wake Forest). Research navigators in ACSMC provides input and navigation of clinical research resources available to diabetes investigators based on extensive experience in diabetes specific studies and methodology and deep knowledge of NCDRC resources available at each institution.
Proper citation: North Carolina Diabetes Research Center Advanced Clinical Study Methods Core Facility (RRID:SCR_022908) Copy
Provides diabetes researchers at University of Colorado with access to microscopy and mass cytometry systems. Provides expertise and training to use equipment effectively for diabetes related tissues; expertise and validated diabetes related resources to prepare samples appropriately; guidance to design experiments; resources to analyze data; assistance with data interpretation.
Proper citation: University of Colorado Anschutz Medical Campus Diabetes Research Center Cell and Tissue Analysis Core Facility (RRID:SCR_022906) Copy
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