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SciCrunch Registry is a curated repository of scientific resources, with a focus on biomedical resources, including tools, databases, and core facilities - visit SciCrunch to register your resource.
https://github.com/bedops/bedops
A suite of tools to address common questions raised in genomic studies - mostly with regard to overlap and proximity relationships between data sets.
Proper citation: BEDOPS (RRID:SCR_012865) Copy
http://bioinf.wehi.edu.au/featureCounts/
A read summarization program, which counts mapped reads for the genomic features such as genes and exons.
Proper citation: featureCounts (RRID:SCR_012919) Copy
http://www.bioconductor.org/packages/release/bioc/html/BicARE.html
Biclustering Analysis and Results Exploration.
Proper citation: BicARE (RRID:SCR_012881) Copy
http://www.bioconductor.org/packages/release/bioc/html/charm.html
Function for differentially methylated regions (DMR) detection that is a part of the charm package in R/Bioconductor.
Proper citation: dmrFinder (RRID:SCR_012853) Copy
http://www.bioconductor.org/packages/release/bioc/html/ChIPpeakAnno.html
Software package that includes functions to retrieve the sequences around the peak, obtain enriched Gene Ontology terms, find the nearest gene, exon, miRNA or custom features such as most conserved elements.
Proper citation: ChIPpeakAnno (RRID:SCR_012828) Copy
http://www.bioconductor.org/packages/release/bioc/html/inSilicoMerging.html
Collection of techniques to remove inter-study bias when combining gene expression data originating from different studies.
Proper citation: inSilicoMerging (RRID:SCR_012829) Copy
http://bioconductor.org/packages/release/bioc/html/DEXSeq.html
Software package focused on finding differential exon usage using RNA-seq exon counts between samples with different experimental designs. It provides functions that allows the user to make the necessary statistical tests based on a model that uses the negative binomial distribution to estimate the variance between biological replicates and generalized linear models for testing. The package also provides functions for the visualization and exploration of the results.
Proper citation: DEXSeq (RRID:SCR_012823) Copy
http://www.bioconductor.org/packages/2.12/bioc/html/snapCGH.html
Software providing methods for segmenting, normalising and processing aCGH data; including plotting functions for visualising raw and segmented data for individual and multiple arrays.
Proper citation: snapCGH (RRID:SCR_012947) Copy
http://www.fda.gov/ScienceResearch/BioinformaticsTools/Arraytrack/default.htm
THIS RESOURCE IS NO LONGER IN SERVICE. Documented on May 23,2023. Provides an integrated solution for managing, analyzing, and interpreting microarray gene expression data.
Proper citation: ArrayTrack (RRID:SCR_012839) Copy
http://www.bioconductor.org/packages/release/bioc/html/miRNApath.html
Software package that provides pathway enrichment techniques for miRNA expression data.
Proper citation: miRNApath (RRID:SCR_012833) Copy
Software tool that screens DNA sequences for interspersed repeats and low complexity DNA sequences. The output of the program is a detailed annotation of the repeats that are present in the query sequence as well as a modified version of the query sequence in which all the annotated repeats have been masked (default: replaced by Ns). Currently over 56% of human genomic sequence is identified and masked by the program. Sequence comparisons in RepeatMasker are performed by one of several popular search engines including nhmmer, cross_match, ABBlast/WUBlast, RMBlast and Decypher. RepeatMasker makes use of curated libraries of repeats and currently supports Dfam ( profile HMM library ) and RepBase ( consensus sequence library ).
Proper citation: RepeatMasker (RRID:SCR_012954) Copy
http://www.bioconductor.org/packages/release/bioc/html/sva.html
Contains functions for removing batch effects and other unwanted variation in high-throughput experiment.
Proper citation: sva package (RRID:SCR_012836) Copy
http://bioconductor.org/packages/release/bioc/html/DNaseR.html
A R package that enables the identification of protein binding footprints in DNase I hypersensitive sites sequencing (DNase-seq) data.
Proper citation: DNaseR (RRID:SCR_012819) Copy
http://sourceforge.net/projects/acaciaerrorcorr/?source=navbar
Accurate error-correction of amplicon pyrosequences.
Proper citation: Acacia (RRID:SCR_012896) Copy
http://www.bioconductor.org/packages/devel/bioc/html/TargetScore.html
Software to infer the posterior distributions of microRNA targets by probabilistically modelling the likelihood microRNA-overexpression fold-changes and sequence-based scores.
Proper citation: TargetScore (RRID:SCR_012933) Copy
https://sites.google.com/site/oncosnp/
An analytical software tool for characterizing copy number alterations and loss-of-heterozygosity (LOH) events in cancer samples from SNP genotyping data.
Proper citation: OncoSNP (RRID:SCR_012985) Copy
http://www.bioconductor.org/packages/2.12/bioc/html/RLMM.html
A Genotype Calling Algorithm for Affymetrix SNP Arrays.
Proper citation: RLMM (RRID:SCR_012984) Copy
http://sourceforge.net/projects/ibdld/
A C++ software program for multipoint IBD estimation based on high density SNP genotype data.
Proper citation: IBDLD (RRID:SCR_013043) Copy
http://sourceforge.net/projects/solsnp/
A Java-based DNA variant calling tool for Next-Generation Sequencing alignment data.
Proper citation: SolSNP (RRID:SCR_013045) Copy
http://sourceforge.net/projects/tumorhats/
A software tool that calls the amplified alleles, and thus amplified haplotype, in copy number aberration regions in next generation sequencing tumor data.
Proper citation: HATS (RRID:SCR_013044) Copy
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