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http://www.stritch.luc.edu/depts/path/residency/anatomic_pathology.htm#Neuropathology

THIS RESOURCE IS NO LONGER IN SERVICE, documented August 31, 2016. A medical center with a neuropathology research program focused on the normal and abnormal aging process of the central nervous system and a funding source for research. The center serves as a collection site for brains in order to study normal aging and neurodegenerative diseases like Alzheimer's.

Proper citation: Loyola University Medical Center / Hines VA Brain Bank (RRID:SCR_013277) Copy   


http://ohsu.eagle-i.net/i/0000012e-5e3a-7084-4106-535b80000000

In cooperation with the Data and Clinical Cores at the Layton Center, the Biomarkers and Genetics Core generates and maintains biomarker data for select biomarkers which have established roles in the characterization of subjects with or at risk of dementia. Biological markers of brain aging, dementia risk, and neurodegeneration have the potential to accelerate the identification of disease mechanisms and treatment strategies. Biomarkers may include genes, proteins, or other metabolites, and may be identified in DNA, cerebrospinal fluid (CSF), or plasma. Apolipoprotein E (APOE) genotype is generated for all research subjects. Sub-groups of subjects have other types of biomarker data. Many subjects have had genome-wide SNP data generated. In order to foster collaborative research as well as expand resources and expertise, samples (DNA, CSF, and plasma) and data are distributed to qualified investigators worldwide. Most of these researchers are pursuing the causes and modifiers of dementia. Data and samples are collected from well characterized research subjects including the healthy elderly and dementia patients.

Proper citation: Layton Alzheimers Disease Center Biomarkers and Genetics Core Lab (RRID:SCR_009911) Copy   


http://ohsu.eagle-i.net/i/0000012e-5e56-c3be-4106-535b80000000

THIS RESOURCE IS NO LONGER IN SERVICE.Documented on December 6th,2022. The Oregon Alzheimer?s Disease Center?s (OADC) Clinical Core program, directed by Dr. Jeffrey Kaye, performs longitudinal studies of the natural history of brain aging and Alzheimer''s disease in patients and healthy control volunteers. These studies which are performed through standardized neurological, neuro-psychological, and brain-imaging assessments are carried out in the Alzheimer''s Disease and Memory Assessment Clinics as well as through community-based assessments conducted in the homes of study volunteers. The Layton Center Neuroimaging Lab conducts brain-imaging MRI brain scans to assist in diagnosis of brain disease. Typically, MRI images are taken from three different planes. These planes are known as the coronal plane, sagittal plane and the axial plane. Each series of MRI images is named after the plane from which they were obtained. The Clinical Core?s research is focused on preclinical and early Alzheimer?s disease (AD) yet is also poised to participate in other relevant new research as it arises. The OADC Clinical Core recruits, assesses and follows individuals from population groups at high risk for dementia such as: the healthy ?oldest old?, subjects with family history of AD, and subjects with Mild Cognitive Impairment (MCI). Research with underserved populations The Oregon Alzheimer?s Disease Center also maintains two Satellite programs to enhance understanding of underserved populations: The Klamath Exceptional Aging Project (KEAP) is a community-based study of brain aging being conducted in Klamath Falls. The African American Dementia and Aging Project (AADAPt) s a Portland-based cohort of 100 African American seniors.

Proper citation: Layton Alzheimers Disease Center Clinical Core (RRID:SCR_009912) Copy   


http://ohsu.eagle-i.net/i/0000012e-5dd8-5be1-4106-535b80000000

THIS RESOURCE IS NO LONGER IN SERVICE. Documented on December 5th,2022. The Education and Information Core of the Layton Aging & Alzheimer?s Disease Center develops and carries out a wide range of educational programs to: * Increase public awareness and understanding of Alzheimer''s Disease research, * Aid in the recruitment of subjects for research studies, and * Improve care and quality of life for persons with dementia and support their family caregivers. Our educational activities include: * Training for health care professionals which include seminars and lectures and we also provide ?hands-on? experiences for medical students, * Community education on Alzheimer''s disease and related dementia disorders, * Workshops on doctor ? patient communication for families and caregivers, * Collaboration with community organizations and groups to promote awareness of the disease and publicize research activities, a particular focus is underserved populations including rural communities and minority groups, * Collaboration with other organizations that serve patients and families, e.g., the Alzheimer?s Association and other state and local agencies that serve the elderly and the loved ones who care for them, and * Distribution of printed material that provides topical information on a variety of subjects related to Alzheimer?s disease and dementia and how best to provide quality of life to those with the disease. * A newsletter, Aging & Alzheimer''s Update, which is published twice per year. The Education Core administers the Oregon Income Tax Check-off Alzheimer''s Research Fund in collaboration with The Oregon Partnership for Alzheimer''s Research, a community advisory committee.

Proper citation: Layton Aging and Alzheimers Disease Center Education Core (RRID:SCR_009909) Copy   



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