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http://www.massgeneral.org/csibd/cores/genetic.aspx

Core whose services include breeding and maintenance of mutant mouse stocks, characterization of murine models, bone marrow transfers and adoptive T cell transfers, in vivo tracking of fluorescently labeled bacteria and cells, and whole body imaging of bioluminescent and fluorescent signals.

Proper citation: Center for the Study of Inflammatory Bowel Disease Genetic Animal Models Core (RRID:SCR_015238) Copy   

•   Source: SciCrunch Registry

https://cdtr.wustl.edu/our-cores/administrative-core/

Management core whose main functions include organizing and managing membership committees, coordinating communication with the NIH and other research bases, and overseeing the use of funds.

Proper citation: Washington University Center for Diabetes Translation Research Administrative Core in Diabetes Research Core (RRID:SCR_015235) Copy   

•   Source: SciCrunch Registry

https://keck.usc.edu/liver-diseases-research-center/about-the-center/scientific-cores/

Core that provides standard and customized slide preparation, liver histochemistry and immunohistochemistry as well as laser-capture microscopy.

Proper citation: USC Liver Transplant Program and Center for Liver Disease Liver Histology Core (RRID:SCR_015236) Copy   

•   Source: SciCrunch Registry

http://www.kidneycenter.pitt.edu/cores/model_organisms.html

Core that uses the yeast S. cerevisiae and the zebrafish D. rerio to dissect fundamental aspects of kidney development and protein structure and function.

Proper citation: Pittsburgh Center for Kidney Research Model Organisms (RRID:SCR_015288) Copy   

•   Source: SciCrunch Registry

http://www.kidneycenter.pitt.edu/cores/imaging_core.html

Core that provides qualitative and quantitative image analysis of the kidney and lower urinary tract through performing light and electron microscopic analysis of epithelial cells and tissues, quantifying and reconstructing kidney and lower urinary tract-associated tissues and organs in 3D, and visualizing and quantifying molecular and cellular dynamics in living animals.

Proper citation: Pittsburgh Center for Kidney Research Kidney Imaging (RRID:SCR_015289) Copy   

•   Source: SciCrunch Registry

https://www.uab.edu/medicine/obriencenter/cores/clinical-studies-of-aki-core

Core facility which provides investigators access to patients with AKI through an established international network of collaborating investigators. It also provides core resources to support the design and conduct of clinical research in AKI and genomics resources to perform systematic genomic analyses and allow correlation with clinical phenotypic information.

Proper citation: UAB-UCSD Core Center for Acute Kidney Injury Research Clinical Studies of AKI (RRID:SCR_015287) Copy   

•   Source: SciCrunch Registry

http://sharedresources.fredhutch.org/core-facilities/comparative-medicine

THIS RESOURCE IS NO LONGER IN SERVICE.Documented on July 27,2022. Core facility that provides a variety of animal housing, veterinary and research support services.

Proper citation: Fred Hutchinson Cancer Research Center Co-operative Center for Excellence in Hematology Comparative Medicine (RRID:SCR_015326) Copy   

•   Source: SciCrunch Registry

http://medicine.iupui.edu/neph/obrien/biosensor

Core facility which develops, characterizes and validates fluorescence protein biosensors for intravital multiphoton microscopy.

Proper citation: Indiana O'Brien Center for Advanced Microscopic Analysis Biosensor Development Core (RRID:SCR_015281) Copy   

•   Source: SciCrunch Registry

http://www.kidneycenter.pitt.edu/cores/cell_physiology.html

Core that provides investigators with in vitro systems for the study of transport processes at the molecular, cell, and epithelial levels.

Proper citation: Pittsburgh Center for Kidney Research Cellular Physiology (RRID:SCR_015284) Copy   

•   Source: SciCrunch Registry

http://www.kidneycenter.pitt.edu/cores/single_nephron_core.html

Core that offers functional (in vitro microperfusion of isolated segments, measurements of transepithelial ion/solute fluxes, fluorescence functional imaging of single tubular cells), biochemical (microassays of enzyme/transporter activity), molecular (quantitation and analysis of RNA and protein), and analytical (targeted renal metabolomics of interrelated networks of small molecules) strategies applied to microdissected tubules, single cells, and urinary exosomes to address relevant questions proposed by users. It also provides analytical services for determining concentrations of exogenous pharmacological agents and molecular probes achieved within the tissue of interest.

Proper citation: Pittsburgh Center for Kidney Research Single Nephron and Metabolomics (RRID:SCR_015285) Copy   

•   Source: SciCrunch Registry

https://www.uab.edu/medicine/obriencenter/cores/biostatistics-core

Core provides statistical expertise in the conceptualization and design of projects, expertise in data management for the resulting clinical and bioinformatics data, and assistance with the preparation of project reports, presentations and manuscripts.

Proper citation: University of Alabama at Birmingham-University of California San Diego O'Brien Center for Acute Kidney Injury Research Biostatistical Core (RRID:SCR_015283) Copy   

•   Source: SciCrunch Registry

http://sharedresources.fredhutch.org/core-facilities/genomics

THIS RESOURCE IS NO LONGER IN SERVICE.Documented on July 27,2022. Core facility that provides expertise and support for generating genomics-based data. Services for DNA arrays, genetic analysis, and high-throughput screening are provided through three specialized laboratories.

Proper citation: Fred Hutchinson Cancer Research Center Co-operative Center for Excellence in Hematology Genomics Shared Resource (RRID:SCR_015327) Copy   

•   Source: SciCrunch Registry

http://obriencenter.yale.edu/mousecelllines.aspx

Core provides services to generate unique in vivo mouse models and kidney specific cell lines.

Proper citation: George M. O'Brien Kidney Center at Yale Mouse Genetics and Cell Line Core (RRID:SCR_015299) Copy   

•   Source: SciCrunch Registry

http://obriencenter.yale.edu/humangenetics.aspx

Core that provides infrastructure support for several key steps in translational research, including development of HIC protocols, patient recruitment, patient DNA extraction and archiving, tools for high throughput SNP genotyping and DNA sequencing, and analysis of genetic linkage and linkage disequilibrium.

Proper citation: George M. O'Brien Kidney Center at Yale Human Genetics and Clinical Research Core (RRID:SCR_015298) Copy   

•   Source: SciCrunch Registry

http://cihd.cores.utah.edu/ironheme/

Core facility that provides analysis of metals, precursor porphyrins and heme for cell pellets, tissue, whole blood, urine, feces and other complex biological materials. It also provides measurements of activity of the enzymes responsible for heme biosynthesis for cell pellets, tissue and blood.

Proper citation: Center for Iron and Heme Disorders at the University of Utah Iron and Heme Core (RRID:SCR_015336) Copy   

•   Source: SciCrunch Registry

http://www.utsouthwestern.edu/research/core-facilities/obrien-kidney/core-services/clinical-translational-core.html

Core whose aim is to translate basic science research into effective diagnostic and therapeutic strategies that will improve the lives of patients by interrupting the pathogenesis of chronic kidney disease and its attendant high risk of cardiovascular disability and death. It combines comprehensive human genetics with phenotyping of subjects.

Proper citation: George M. O'Brien Kidney Research Core Center - UT Southwestern Medical Center Clinical and Translational Core (RRID:SCR_015295) Copy   

•   Source: SciCrunch Registry

http://obriencenter.yale.edu/renalphyscore.aspx

Core provides specialized services and training for assessing renal function in small animals at the level of single tubules in vitro and in vivo (e.g. micropuncture, microperfusion, and tubule-specific microdissection), the whole kidney (e.g. clearance studies in anesthetized animals, perfusion fixation for histology studies), and the intact organism (e.g. balance studies in metabolic cages, acute and chronic BP measurements).

Proper citation: George M. O'Brien Kidney Center at Yale Renal Physiology Core (RRID:SCR_015296) Copy   

•   Source: SciCrunch Registry

https://www.cincinnatichildrens.org/research/divisions/n/nephrology/biomarker-lab

Core whose goals are to provide high throughput Clinical Biofluid Profiling Services (including initial web-based and in-person consultation, study design, sample preparation and processing, data acquisition, data analysis, protein purification, target identification, and specific assay development and validation) and services pertaining to Biomarker measurement and validation (including design of ELISA and Western Blots, measurement of known and emerging markers of acute and chronic kidney diseases, as well as consultation for biomarker statistics and clinical trials design).

Proper citation: Pediatric Centers of Excellence in Nephrology at Cincinnati Children's Hospital Medical Center Biomarker Core (RRID:SCR_015300) Copy   

•   Source: SciCrunch Registry

http://livercenter.yale.edu/core-facilities/morphology-core-facility.aspx

Core facility that provides instrumentation and technical expertise for the preparation, acquisition and analysis of images of cells and tissues at the light microscopic level. Its services include confocal and super-resolution microscopy, epifluorescent microscopy with quantitative and ratio imaging, timelapse microscopy with image processing and analysis, multiphoton microscopy, and cryosectioning.

Proper citation: Yale Liver Center Morphology Core (RRID:SCR_015264) Copy   

•   Source: SciCrunch Registry

https://digestivediseasescenters.org/content/ddrc-uab-molecular-pathology-and-human-celltissue-core

Core that provides both morphological analysis of mucosal tissues and instructs investigators in the techniques used to prepare tissue sections and analyze the morphology and cellular components of the mucosa and primary human gut (intestinal and rectal) cells, gastric mononuclear cells and genital (cervical and vaginal) cells and instruction on how to construct mucosal tissue explants in a transwell chamber system.

Proper citation: Mucosal HIV and Immunobiology Center Molecular Pathology and Human Cell and Tissue Core (RRID:SCR_015265) Copy   

•   Source: SciCrunch Registry