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https://hddc.hms.harvard.edu/gnotobiotics-microbiology-and-metagenomics

Core facility that assists investigators evaluating host microbiota and its role in normal physiology and disease. It includes a number of resources for groups studying the role of the microbiota in human health and disease.

Proper citation: Harvard Digestive Diseases Center Biomedical CORE D: Gnotobiotic Mice, Microbiology and Metagenomics (RRID:SCR_012319) Copy   

•   Source: SciCrunch Registry

http://www.scienceexchange.com/facilities/molecular-biology-core-mmc

Multi-functional facility that provides primary service of DNA sequencing, access to shared equipment housed in a centralized location, access to frequently used molecular biological reagents. The Core also maintains an Invitrogen Supply Center that stocks many routinely used reagents for molecular biological research. Core staff facilitate through the Meharry-Vanderbilt Alliance the ordering of reagents and supplies.

Proper citation: Meharry Medical College Molecular Biology Core Facility (RRID:SCR_012283) Copy   

•   Source: SciCrunch Registry

http://www.scienceexchange.com/facilities/advanced-histology-services

The objective of the Morphology and Phenotyping Core - Advanced Histology Services, is to provide Investigators/clients with the tools and expertise to process and analyze tissue samples. The Core is able to process any type of animal and/or human tissue for research purposes. Our technicians are also highly trained in dermatology and delicate specimen handling. We consistently maintain the highest-quality results by utilizing state-of-the-art equipment and employing nationally-certified technicians. Our aim is to always provide excellent customer service by fulfilling each Investigators/clients'''' specific needs and wants. Core services include recommendations for tissue harvesting and storage, preparation of paraffin blocks, sectioning of paraffin and frozen blocks, standard H&E histology, special staining procedures, and control slide preparation.

Proper citation: CU Denver Advanced Histology Services (RRID:SCR_012286) Copy   

•   Source: SciCrunch Registry

https://crl.berkeley.edu/molecular-imaging-center/

Core microscopy facility managed by Cancer Research Laboratory. Provides campus community with training and access to state-of-the-art light microscopy equipment. Now in two locations: Life Sciences Addition Building (LSA) and the new Li Ka-Shing Center for Biomedical and Health Sciences (LKS). The MIC specializes in live cell imaging, confocal, multi-photon, fluorescent lifetime imaging (FLIM), and equipment for optogenetic research.

Proper citation: UC Berkeley Molecular Imaging Center Core Facility (RRID:SCR_012285) Copy   

•   Source: SciCrunch Registry

https://ragon.partners.org/musiebiostats/

Biostatistics core serves the needs of the HIV/AIDS researchers within the Ragon Institute and its affiliates at Harvard, MGH, MIT and University of Kwazulu Natal, South Africa. Provides expertise in planning, conduct and analysis of research with goal of enhancing scientific quality of HIV-related research at the institute. Primary objective is to ensure that studies are well designed, correctly analyzed, clearly presented, and correctly interpreted.

Proper citation: Massachusetts General Hospital Ragon Institute Biostatistics Core Facility (RRID:SCR_012323) Copy   

•   Source: SciCrunch Registry

http://www.scienceexchange.com/facilities/histopathology-core

Both animal model and clinical research require the production of high quality tissue samples for morphological and molecular analyses. The NYU Histopathology Core, one component of the Experimental Pathology Shared Resources provides?_services, instrumentation and training to facilitate the generation of these critical materials. Services offered by the Histopathology Core include: tissue preparation, processing, embedding, sectioning, histochemical staining, digital whole slide scanning, and laser capture microdissection of both animal and fixed human tissues. The Histopathology Core also makes available several instruments for investigator use on a self-serve basis. This option is valuable for researchers who wish to direct certain stages of specimen preparation and is more cost-effective in some cases. Available instrumentation includes a state-of the-art Laser Dissection Microscope, a microtome, a cryostat and a microscope fitted with a digital camera. Training is provided by Core staff. The components of pricing for each service include the cost of consumables, the cost for technician time for each service, and a small percentage of any associated service contracts. As with many of our services, the incremental cost of each procedure is affected by overall volume; as volume increases, we pass the resulting savings on to users in the form of reduced prices.

Proper citation: NYU Histopathology Core (RRID:SCR_012409) Copy   

•   Source: SciCrunch Registry

https://www.moffitt.org/research-science/shared-resources/small-animal-imaging-lab/

Core provides advanced and affordable multi-modality imaging services including consultation, imaging and image analysis for both basic and translational research. Offers instrumentation including 7T MRI, multimodal PET/SPECT/CT, ultrasound and optical modalities. Used to evaluate tumor development, progression, metastasis and therapy response in rodent models of cancer including development of imaging biomarkers, contrast agents and tumor targeting agents, evaluating tumor metabolism and microenvironment, and high-resolution anatomical imaging of human specimens.

Proper citation: Moffitt Cancer Center Small Animal Imaging Laboratory Core Facility (RRID:SCR_012401) Copy   

•   Source: SciCrunch Registry

http://www.scienceexchange.com/facilities/laboratory-of-ion-beam-nanotechnologies-skobeltsyn-institute-of-nuclear-physics-msu

An Core facility

Proper citation: MSU Skobeltsyn Institute of Nuclear Physics Laboratory of Ion Beam Nanotechnologies (RRID:SCR_012372) Copy   

•   Source: SciCrunch Registry

https://pharmacycorefacilities.usc.edu/translational-lab/

Core is equipped with a wide variety of technologically advanced instruments essential for cutting edge biomedical discovery and therapeutic development research. TRLab is composed of two major units. The Computational Bioinformatics Unit houses graphic workstations and modeling programs that enable in silico virtual screening and rational drug design applications. The Therapeutic Screening Unit houses a number of specialized instruments that enable a broad range of automated and multiplexed biological analyses in a throughput manner. The core mission of the TRLab has been to provide investigators with a state-of-the-art technological platform and technical expertise to advance translational research endeavors in the School of Pharmacy and at USC.

Proper citation: University of Southern California School of Pharmacy Translational Research Laboratory (RRID:SCR_012253) Copy   

•   Source: SciCrunch Registry

http://www.scienceexchange.com/facilities/proteomics-and-metabolomics-facility-welcome

THIS RESOURCE IS NO LONGER IN SERVICE. Documented on April 25,2024. The mission of the Proteomics and Metabolomics Facility is to serve as an enabling resource for research and development programs at Colorado State University. We strive to build instrumental capabilities that exceed the normal resources of individual research programs, and make those technologies available as a shared resource. We also aim to provide an environment rich in expertise and educational resources, and to foster collaboration across the CSU community and beyond.

Proper citation: CSU Proteomics and Metabolomics Facility (RRID:SCR_012255) Copy   

•   Source: SciCrunch Registry

http://www.scienceexchange.com/facilities/the-laboratory-for-developmental-biology

THIS RESOURCE IS NO LONGER IN SERVICE. Documented on April 22, 2024. Laboratory for Developmental Biology was established to help scientists at the Institute of Molecular Medicine and the University of Texas conduct research that requires the production of transgenic and knock-out animal models of human diseases.

Proper citation: UTHealth Laboratory for Developmental Biology (RRID:SCR_012259) Copy   

•   Source: SciCrunch Registry

https://ophthalmology.pitt.edu/research/core-research-facilities/tissue-culture-histology-module

Core offers Tissue Culture Services including Basic Cell Culture, Specialized Culture Services, Virus Services; Histology Services including Paraffin Histology, Frozen Histology, Monolayers,Personnel Training and more.

Proper citation: University of Pittsburgh Department of Ophthalmology Tissue Culture and Histology Module Core Facility (RRID:SCR_012412) Copy   

•   Source: SciCrunch Registry

http://www.scienceexchange.com/facilities/chemodiversity-laboratory-cddi

The chemodiversity core facility offers a library of natural product-derived crude extracts, fractions and pure compounds for screening. Gas chromatography high-resolution mass spectrometry (MS) analysis, liquid chromatography MS targeted separation and high throughput screening (targeting solid tumor cell lines, anti-microbial activity, permeability and drug solubility determination) are provided. The services also include general chromatography (MPLC, HPLC) and spectrometric characterization (UV, IR) as well as microbiology workspace (biosafety cabinets), synthesis activities and training. Our facility offers advanced instrumentation (GC/MS Q-TOF, IR, UV, MPLCs, HPLCs, liquid handling robots, biosafety cabinets, and other essential lab equipment), consultation and services for sample isolation and analysis, derivatization and scale-up. Sample preparation and safety training are also available for commercial and USF clients using our chromatographic and analytical instrumentation.

Proper citation: USF Chemodiversity Laboratory (RRID:SCR_012262) Copy   

•   Source: SciCrunch Registry

http://www.scienceexchange.com/facilities/mass-spectrometry-biological-applications-and-high-throughput-proteomics-facility-cddi

The Mass Spectrometry, Biological Applications and High-Throughput Proteomics Facility is dedicated to the identification and quantification of components associated with complex biological matrices. The main goal of our lab is to produce high quality data related to any biological or environmental sample, i.e. cancer, Alzheimer_������_s, diabetes, cardiovascular disease, and parasitology, to name a few. To see a full list of facility activity, please visit our listed website.

Proper citation: USF Mass Spectrometry Biological Applications and High-Throughput Proteomics Facility (RRID:SCR_012261) Copy   

•   Source: SciCrunch Registry

http://www.scienceexchange.com/facilities/mcgill-spr-facility

For applications including proteomics, drug discovery, immunogenicity, and food analysis, state-of-the-art Surface Plasmon Resonance (SPR) technology allows for label-free, real-time biomolecular interaction analysis. Using purified preparations or complex mixtures, binding interactions between proteins, lipids, carbohydrates, nucleic acids, small molecules, and cells/viruses can be examined quantitatively in their native state with low sample consumption. In a typical experiment, the ligand (_������������bait_������_) is immobilized to a gold-plated sensor chip and repeated injections of analyte (binding partner _������������target_������_) are then flowed overtop.

Proper citation: McGill SPR Facility (RRID:SCR_012265) Copy   

•   Source: SciCrunch Registry

http://www.massgeneral.org/psychiatry/research/pngu_home.aspx

Core facility that provides the following services: SNP genotyping, qPCR for CNV detection / confirmation, Genetic analysis services, DNA extraction, quantification, sample preparation, tracking, and storage. This resource provides custom genotyping (SNP, other), qPCR for CNV detection/confirmation, DNA extraction, quantification, sample preparation, tracking, and storage, and related services to further the PNGU mission of identifying and characterizing the genetic basis of psychiatric, behavioral, and neurodevelopmental disorders and to translate these discoveries to improvements in clinical care and public health.

Proper citation: MGH Psychiatric and Neurodevelopmental Genetics Unit Core Lab (RRID:SCR_012301) Copy   

•   Source: SciCrunch Registry

http://www.scienceexchange.com/facilities/genomics-core-facility--8

The facility aims to provide scientists at Stony Brook with the tools required to maximize their research. In the longer term, it is hoped that this facility will pave the way for Stony Brook to become a center of excellence in translational medicine, with particular emphasis on human genetics.

Proper citation: Stony Brook Medicine Genomics Core Facility (RRID:SCR_012389) Copy   

•   Source: SciCrunch Registry

http://www.scienceexchange.com/facilities/center-for-health-informatics-and-bioinformatics-nyu

THIS RESOURCE IS NO LONGER IN SERVICE. Documented on August 4th, 2023. Handles both low-level (instrument-specific, or upstream) informatics as well as higher-level (hypothesis testing and generation oriented, or downstream informatics). CHIBI also has the scientific responsibility for the high-end computing needed to process the genomic data.

Proper citation: New York University Center for Health Informatics and Bioinformatics (RRID:SCR_012300) Copy   

•   Source: SciCrunch Registry

http://www.scienceexchange.com/facilities/pathology-resource-network

THIS RESOURCE IS NO LONGER IN SERVICE. Documented on May 2,2024. New York State Department of Health Provisional License for Tissue Bank Operation issued in accordance with and pursuant to section 4364 Public Health Law of New York State. Tissue Bank ID No.: NA002 Approved for the following categories of Service: Cancer tissue and associated non-cancer tissue for use in medical research and/or education

Proper citation: RPCI Pathology Resource Network (RRID:SCR_012388) Copy   

•   Source: SciCrunch Registry

https://www.usf.edu/arts-sciences/departments/chemistry/research/core-facilities/nmr.aspx

NMR facility provides state-of-the-art ultra-high field (14 and 18 Tesla) instruments that enable researchers to characterize protein structure at atomic resolution (along with the characterization of small molecules). Technical support and training are available for all aspects of project development. Experiments include structure elucidation of small molecules (e.g. synthetic molecules, natural products, and small peptides etc.) to studying advanced protein-ligand interactions.

Proper citation: USF NMR Laboratory (RRID:SCR_012260) Copy   

•   Source: SciCrunch Registry