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SciCrunch Registry is a curated repository of scientific resources, with a focus on biomedical resources, including tools, databases, and core facilities - visit SciCrunch to register your resource.

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Resource Name Proper Citation Abbreviations Resource Type Description Keywords Resource Relationships Related Condition Funding Defining Citation Availability Website Status Alternate IDs Alternate URLs Old URLs Parent Organization Resource ID Synonyms Record Last Update Mentions Count
Harvard PCMM Flow and Imaging Cytometry Resource
 
Resource Report
Resource Website
1+ mentions
Harvard PCMM Flow and Imaging Cytometry Resource (RRID:SCR_009839) core facility, access service resource, service resource The Flow and Imaging Cytometry Resource provides research flow and imaging cytometry services to all investigators in the PCIMM at Children''s Hospital, Boston and Immune Disease Institute, HMS and the local scientific community on a case-by-case basis. With state of the art instrumentation, such as the standard configuration 3-lasers FACSAria located in BL2+-facility, 20-parameters 4-lasers FACSAria SORP and DIVA FACSVantage SE TurboSort?, the facility offers high speed cell sorting and complex analytical services, development of collaborative projects as well as consulting on design and development of new protocols and methods. is listed by: Eagle I
has parent organization: Harvard University; Cambridge; United States
nlx_156322 http://www.idi.harvard.edu/about_us/core_facilities/flow_and_imaging_cytometry
http://www.flowimagingcytometry.org/
SCR_009839 2026-02-13 10:56:30 1
DartMouse - Speed Congenics
 
Resource Report
Resource Website
1+ mentions
DartMouse - Speed Congenics (RRID:SCR_009757) core facility, access service resource, service resource Core facility that provides the following services: Medium-density speed congenic backcross service, Medium-density genetic background check service, DNA extraction. DartMouse is a not-for-profit core facility funded by the National Institutes of Health''s National Center for Research Resources. The mission of DartMouse is to facilitate the development of congenic mice in support of pre-clinical projects across the United States. Use of DartMouse allows the generation of congenic mice in 5 generations (~1.5 years), versus the 10 generations (~3 years) required by conventional back-crossing. Facility staff provides expert advice on mouse speed congenic development, mouse genetic background analysis, and mouse genetic mapping. Investigators provide us with mouse tail clippings. From these, DartMouse isolates genomic DNA and performs and analyzes complete genome-wide scans. We return data in graphical and spreadsheet formats, and make specific recommendations on breeder selection. We operate an Illumina BeadStation 500. Chips use a 1449 SNP array covering the mouse genome with an average density of <5 cM. congenic backcrossing, dna extraction is listed by: Eagle I
has parent organization: Dartmouth College; New Hampshire; USA
nlx_156218 http://cancer.dartmouth.edu/res/speed_congenics.html
http://dartmouth.eagle-i.net/i/0000012a-24fd-26a9-d8a1-249280000000
SCR_009757 Dartmouth DartMouse - Speed Congenics 2026-02-13 10:56:29 3
DFCI RNA Interference Screening Facility
 
Resource Report
Resource Website
DFCI RNA Interference Screening Facility (RRID:SCR_009755) core facility, access service resource, service resource Core facility that provides the following services: Genome-scale screening of lentiviral human and mouse shRNA libraries.

The RNAi Screening Facility provides investigators with access to RNAi reagents and high-throughput screening technology. Lentiviral-based RNAi constructs against the human and mouse genomes are provided by the RNAi Consortium of the Broad Institute, and can be used to transduce a wide range of target cells, including primary and non-dividing cells. The Facility provides reagents, equipment, and technical expertise to design, optimize, and perform cell-based, arrayed lentiviral RNAi screens. Additionally, lentiviral RNAi constructs against individual genes can be requested.
viral infection is listed by: Eagle I
has parent organization: Dana-Farber Cancer Institute
nlx_156215 SCR_009755 2026-02-13 10:56:30 0
DFCI Shannon McCormack Advanced Molecular Diagnostics Laboratory
 
Resource Report
Resource Website
DFCI Shannon McCormack Advanced Molecular Diagnostics Laboratory (RRID:SCR_009756) core facility, access service resource, service resource The Molecular Diagnostics Laboratory provides such research services as microRNA expression profiling, human cell line identity verification, mutation detection for clinical research studies, and specimen processing for clinical research studies to investigators at the Dana Farber Cancer Institute, as well as to investigators at other institutions. Consultation on experimental design and assistance with data analysis are also available. is listed by: Eagle I
has parent organization: Dana-Farber Cancer Institute
nlx_156216 SCR_009756 2026-02-13 10:56:29 0
Dana-Farber Cancer Institute Molecular Biology Core Facility
 
Resource Report
Resource Website
1+ mentions
Dana-Farber Cancer Institute Molecular Biology Core Facility (RRID:SCR_009754) MBCF at DFCI core facility, access service resource, service resource Core offers services for genomic next-generation sequencing library preparation, sequencing and analysis applications including RNAseq, ChIPseq, ATACseq, CRISPR screening, whole genome methylation profiling, targeted resequencing, single-cell RNAseq, exome sequencing, and more. Performs bioinformatics analysis such as integration of multi-omics datasets or specialized analyses. Genomics core technology platforms include Illumina NovaSeq6000, NextSeq500s, MiSeqs, MiniSeq. High throughput sample preparation is performed on Beckman Coulter Biomek FX and i7 systems. Low throughput samples are prepared by technical staff. Next generation sequencing, RNAseq, ChIPseq, ATACseq, CRISPR, analysis, dataset, genomics, ABRF is listed by: Eagle I
is listed by: ABRF CoreMarketplace
has parent organization: Dana-Farber Cancer Institute
Open nlx_156214, SCR_018264, ABRF_57 https://coremarketplace.org/?FacilityID=57 http://harvard.eagle-i.net/i/0000012a-2512-3484-5617-794280000000 SCR_009754 , Dana-Farber Cancer Institute Molecular Biology Core Facilities, DFCI Molecular Biology Core Facilities 2026-02-13 10:56:29 1
DFCI Flow Cytometry Core Facility
 
Resource Report
Resource Website
1+ mentions
DFCI Flow Cytometry Core Facility (RRID:SCR_009751) core facility, access service resource, service resource Core facility that provides the following services: Cell Sorting.

The Flow Cytometry Core Facility provides sterile sorting and analysis of samples in support of research at DFCI. The core has 2 high-speed cell sorters, the BD FACSAria II SORP and BD FACSAria IIu with up to 12-color simultaneous detection utilizing multi-laser platforms. Sample populations can be sterile sorted into a variety of tubes or plates. The BD FACSAria II SORP and BD FACSAria IIu are both equipped with the Automated Cell Deposition Unit (ACDU) for sterile sinlge cell sorting into 96, 384 micro titer plates. The core presently has 2 analyzers, the BD LSRFortessa SORP and BD LSRII with up to 12-color simultaneous detection utilizing multi-laser platforms. The BD LSR II is also equipped with an HTS(high throughput sampler) for analyzing samples directly from 96 well micro titer plates as well as being able to run 5ml tubes. The Facility staff is available to assist researchers with their sorting and analysis needs. Researchers who would like to utilize the analyzers are trained so that they can analyze their experiments independently. The staff will assist with data acquisition and analysis as well as interpretation. They will also assist in experiment design and implementation as well as troubleshooting. Training sessions are available for researchers who would like to run their sorting experiments independently.
cellular assay is listed by: Eagle I
has parent organization: Dana-Farber Cancer Institute
nlx_156211 http://flowcytometry.dfci.harvard.edu/ SCR_009751 2026-02-13 10:56:30 1
DFCI Medical Arts Core Facility
 
Resource Report
Resource Website
DFCI Medical Arts Core Facility (RRID:SCR_009752) core facility, access service resource, service resource Core facility that provides the following services: Graphics services, All Research Related Photography.

Medical Arts Core DFCI offers complete services for Publications, Presentations and Advertising as follows: Custom/Computer Graphics illustrations, Design and Consulting full productions services, Photoshop training. Posters Productions/Brochure Printing on best selection of paper, canvas material and Backlit poster films. Lamination, LCD announcements creation and posting. Research Related Photography Equipment: * iMAC and PC computers * Posters printer * LCD electronic announcements TV units * Backlit Display units * Laminator * Scanner * Digital camera
photography is listed by: Eagle I
has parent organization: Dana-Farber Cancer Institute
nlx_156212 http://www.dana-farber.org/Research/Core-Facilities.aspx#medical SCR_009752 2026-02-13 10:56:29 0
DFCI Survey and Data Management Core
 
Resource Report
Resource Website
DFCI Survey and Data Management Core (RRID:SCR_009750) core facility, access service resource, service resource Core facility that provides the following services: Data collection, data entry and analysis, Database design, data management and process tracking, Qualitative data collection, management and analysis.

The Survey and Data Management Core (SDMC) provides efficient, high-quality survey data collection and management services and consultation to support the research needs of investigators and staff throughout the Harvard Medical research community. The Core, housed within the Center for Population Sciences at the Dana-Farber Cancer Institute, is dedicated to rigorous quantitative and qualitative survey data collection and management.
research subject private information management, data entry, data analysis, data acquisition, database development, data management is listed by: Eagle I
has parent organization: Dana-Farber Cancer Institute
nlx_156217 http://surveycore.org/
http://www.dana-farber.org/Research/Core-Facilities.aspx#data
SCR_009750 2026-02-13 10:56:29 0
DF/HCC Tumor Imaging Metrics Core Facility
 
Resource Report
Resource Website
DF/HCC Tumor Imaging Metrics Core Facility (RRID:SCR_009744) core facility, access service resource, service resource Core facility that provides the following services: Reporting and database management service of radiological data for clinical trials, Radiologic exam quality control service.

The mission of the Tumor Imaging Metrics Core (TIMC) is to provide standardized, consistent, longitudinal radiological measurements to evaluate therapeutic response for DF/HCC clinical trials. The TIMC - * Makes reliable, quantitative, longitudinal measurements (such as RECIST, WHO, SWOG, standardized uptake value (SUV) etc.) of lesions from serial MRI, CT, PET, and PET/CT scan images * Presents results of analyses on a password-protected secure web-based report * Provides an independent service, with verifiable measurement of treatment response for patients enrolled in cancer center trials * Serves as a centralized, computerized resource to facilitate efficient internal or external auditing Reliable tracking of changes in lesion size or metabolism is essential for clinical trials that use radiological measurements as surrogate endpoints. The Tumor Imaging Metrics Core provides a service for managing these images, making measurements in a routine, reliable, and centralized way, and making results available to investigators efficiently.
database maintenance, data management, quality control is listed by: Eagle I
has parent organization: Harvard University; Cambridge; United States
nlx_156205 http://www.dfhcc.harvard.edu/core-facilities/tumor-imaging-metrics/
http://harvard.eagle-i.net/i/0000012c-ae0f-b032-02c0-2b6880000000
SCR_009744 DF/HCC Tumor Imaging Metrics Core 2026-02-13 10:56:29 0
DF/HCC Rodent Histopathology Core Facility
 
Resource Report
Resource Website
DF/HCC Rodent Histopathology Core Facility (RRID:SCR_009742) core facility, access service resource, service resource Core facility that provides the following services: Histopathology analysis service, Histopathologic diagnosis training service, Cryosectioning service, Rodent necropsy service, Paraffin sectioning service, Bacteria, fungi, and inclusion bodies histological staining service, Rodent tissue processing, Carbohydrate and mucoproteins histological staining service, Connective tissue and muscle histological staining service, Cytoplasmic granules histological staining service, Fats and lipids histological staining service, Hematologic and nuclear elements histological staining service, Nerve cells and fibers histological staining service, Equipment training service, Equipment access service.

The Rodent Histopathology Core was founded in 1999 as one of the pathology cores within the Dana-Farber/Harvard Cancer Center. The Core was established to provide high quality professional, technical, and educational pathology services. The ultimate goal of the facility has been to support investigator research that leads to the identification of pathologic processes in mice and can be directly translatable to human disease. The core provides an essential and unique service to the many Center members and labs invested in mouse research. While many commercial and academic histology services are available, no other service is available that offers comparable high quality service with rapid turn around time and highly experienced professional supervision. The educational mission of the Core also adds an important dimension.
histology, histological sample preparation, cryosectioning, tissue procurement, tissue sectioning, biological sample processing, tissue embedding is listed by: Eagle I
has parent organization: Harvard University; Cambridge; United States
nlx_156202 http://www.dfhcc.harvard.edu/core-facilities/rodent-histopathology-pathology/services/
http://genepath.med.harvard.edu/pathcore/
SCR_009742 2026-02-13 10:56:29 0
DF/HCC Pathology Specimen Locator
 
Resource Report
Resource Website
DF/HCC Pathology Specimen Locator (RRID:SCR_009741) core facility, access service resource, service resource PSL is a consultative Core with components in each of the five DF/HCC hospitals. We have established a web-based network of autonomous, distributed, searchable databases, which contain de-identified, coded, pathologic information on post-diagnostic, excess human materials (including frozen or paraffin-embedded tissues and bodily fluids). Standardized specimen core dataset includes age, gender, anatomic location, tissue type, and diagnoses. Access to the PSL is through the password-protected Harvard eCommons. Two types of generic PSL uses are envisioned: (1) Center members with eCommons accounts can quickly retrieve aggregated tissue availability information to determine the feasibility of a proposed study. (2) Approved investigators can discover and review materials from suitable, de-identified and coded cases online and then request the samples they want. is listed by: Eagle I
has parent organization: Harvard University; Cambridge; United States
nlx_156201 http://www.dfhcc.harvard.edu/core-facilities/pathology-specimen-locator-pathology/
http://genepath.med.harvard.edu/pathcore/
SCR_009741 2026-02-13 10:56:29 0
HMS West Quad Computing Group
 
Resource Report
Resource Website
HMS West Quad Computing Group (RRID:SCR_009814) core facility, access service resource, service resource The West Quad Computing Group (WQCG) serves the research community of the BCMP and Cell Biology departments at Harvard Medical School. We provide support for your advanced computing needs, including design and maintenance of computational clusters, large data-set management, web and database backed applications, and workstation support, including workstations connected to research equipment. Please see Resources for more information, including a sample of some of our recent projects. We work in collaboration with the HMS Information Technology department. Please contact us using our support form for all of your computer support needs. is listed by: Eagle I
has parent organization: Harvard Medical School; Massachusetts; USA
nlx_156281 http://wqcg.med.harvard.edu/ SCR_009814 2026-02-13 10:56:32 0
FAMU Animal care facility
 
Resource Report
Resource Website
FAMU Animal care facility (RRID:SCR_009779) core facility, access service resource, service resource Core facility that provides the following services: Animal handling training service, Animal surgery. animal handling, small animal surgery is listed by: Eagle I
has parent organization: Florida Agricultural and Mechanical University; Florida; USA
nlx_156246 SCR_009779 2026-02-13 10:56:29 0
Dartmouth Trace Element Analysis Core Facility
 
Resource Report
Resource Website
Dartmouth Trace Element Analysis Core Facility (RRID:SCR_009777) core facility, access service resource, service resource Analysis of elemental composition of biological tissues and fluids by Inductively Coupled Plasma Mass spectrometry. Analysis of Arsenic species in urine and blood by chromatography-ICP-MS. Laser ablation analysis of tissue sections for imaging of elemental distributions. USEDit, ABRF, elemental composition analysis, biological tissues and fluids, Inductively Coupled Plasma Mass spectrometry, Arsenic species in urine and blood, chromatography-ICP-MS, imaging of elemental distributions, is listed by: Eagle I
has parent organization: Dartmouth College; New Hampshire; USA
NIEHS P42ES007373 nlx_156244 https://coremarketplace.org/?FacilityID=276&citation=1
http://www.dartmouth.edu/~toxmetal/program-resources/trace-element-analysis/index.html
http://dartmouth.eagle-i.net/i/0000012a-24fd-a220-d8a1-249280000000 SCR_009777 , Dartmouth Trace Element Analysis Core Laboratory, Dartmouth Trace Element Analysis Laboratory, Trace Element Analysis Laboratory 2026-02-13 10:56:29 0
Dartmouth Translational Research Animal Core
 
Resource Report
Resource Website
Dartmouth Translational Research Animal Core (RRID:SCR_009778) core facility, access service resource, service resource TRAC is affiliated with the the Irradiation and Small Animal Imaging Shared Resource, which together provides irradiation services for basic and translational researchers and state-of-the-art non-invasive in vivo imaging of cultured cells and small animals. Services are used by Dartmouth investigators to irradiate cells in culture and small experimental animals. A separate set of irradiation devices is available through Norris Cotton Cancer Center for clinical and experimental irradiation of human patients. is listed by: Eagle I
has parent organization: Dartmouth College; New Hampshire; USA
nlx_156245 http://geiselmed.dartmouth.edu/hvrc/trac/ SCR_009778 2026-02-13 10:56:29 0
HMS SBGrid Core
 
Resource Report
Resource Website
HMS SBGrid Core (RRID:SCR_009811) core facility, access service resource, service resource The SBGrid Core team provides research computing sysadmin support to structural biology laboratories in the Boston area. is listed by: Eagle I
has parent organization: Harvard Medical School; Massachusetts; USA
nlx_156278 http://core.sbgrid.org/ SCR_009811 2026-02-13 10:56:30 0
Dartmouth SYNERGY: Biomedical Informatics Core
 
Resource Report
Resource Website
Dartmouth SYNERGY: Biomedical Informatics Core (RRID:SCR_009771) Dartmouth BIC core facility, access service resource, service resource Core facility that provides the following services: Research Consulation: Informatics Research.

The Biomedical Informatics Core (BIC) offers clinical and translational investigators support on informatics tools for cohort discovery, data integration, data management, text mining and visual analytics. In addition, the BIC provides consultative services on integration of data systems and on procedures for research data security.
data management, computational modeling technique, image visualization and analysis, secure data storage is listed by: Eagle I
has parent organization: Dartmouth College; New Hampshire; USA
nlx_156235 http://synergy.dartmouth.edu/research_core_bic.html SCR_009771 2026-02-13 10:56:31 0
Dartmouth SYNERGY: Bioregistry
 
Resource Report
Resource Website
Dartmouth SYNERGY: Bioregistry (RRID:SCR_009772) core facility, access service resource, service resource Currently under development, the SYNERGY Bioregistry is a centralized virtual biorepository that will integrate information about samples from existing and future biorepositories. The Bioregistry will comprise: A standardized data warehouse of information on existing research biorepositories at Dartmouth eSample, a research tool to allow tracking of specimens and integration with the Bioregistry Access to the Dartmouth freezer farm of large freezer storage units to support archived materials The Bioregistry will enhance access to a diverse array of biologic samples, allowing investigators to manage sample collection and storage based on individual project needs and enabling researchers to learn about existing samples that can be used to pursue new clinical and translational studies. Bioregistry Director: Margaret Karagas, PhD is listed by: Eagle I
has parent organization: Dartmouth College; New Hampshire; USA
nlx_156236 http://synergy.dartmouth.edu/research_core_bioregistry.html SCR_009772 2026-02-13 10:56:29 0
Dartmouth Pathology Translational Research
 
Resource Report
Resource Website
Dartmouth Pathology Translational Research (RRID:SCR_009770) core facility, access service resource, service resource Core facility that provides the following services: Tissue collection, Histology services, Molecular pathology services, Pathologist consultation.

The Pathology Shared Resource (PSR) provides four primary services for NCCC investigators: # it partners researchers with appropriate pathologists to provide specific expertise matched to the needs of the research project; # it coordinates the procurement, preservation, and distribution of human tissues and cells for funded and developmental NCCC basic and clinical research; # it performs histologic, immunohistologic, and molecular diagnostic procedures including DNA sequencing SNP genotyping and quantitative gene expression analysis for NCCC researchers; and # it provides a GMP cell processing laboratory for the isolation/purification, manipulation, expansion and/or storage of cells derived from a patient''s/subject''s peripheral blood intended for autologous reinfusion. The Pathology Shared Resource is closely integrated with the anatomic pathology laboratory of Mary Hitchcock Memorial Hospital and provides a cost-effective mechanism for NCCC investigators to take advantage of the economic efficiencies provided by that high-volume facility. The Core is managed by the Norris Cotton Cancer Center as a shared resource on behalf of the university and is available to all investigators within the greater Dartmouth research community. This Shared Resource is supported by funds from the Norris Cotton Cancer Center Core Grant and is overseen by the EMTG, an oversight and advisory committee of the Cancer Center.
tissue procurement, immunohistochemistry assay, biological sample processing, histological sample preparation, histology, gene expression analysis assay, laser capture microdissection, dna sequencing, dna extraction, snp interrogation genotyping, rna extraction is listed by: Eagle I
has parent organization: Dartmouth College; New Hampshire; USA
nlx_156233 http://cancer.dartmouth.edu/res/pathology.html SCR_009770 2026-02-13 10:56:29 0
HMS NERCE Microbiology and Animal Resources Core
 
Resource Report
Resource Website
HMS NERCE Microbiology and Animal Resources Core (RRID:SCR_009807) core facility, access service resource, service resource Core facility that provides the following services: Enzyme-linked immunosorbent spot assay service, Fluorescence microscopy service, Real-time PCR Service.

The NERCE Microbiology and Animal Resources Core maintains two laboratories, a BSL-2 and a BSL-3 laboratory, to support the research efforts of all New England investigators conducting research on NIAID priority pathogens. Each laboratory provides the physical environment, equipment, and support personnel required for scientists to work with these agents. The BSL-3 laboratory is an isolated suite that includes individual laboratory rooms and rooms for housing experimental animals, all within a single containment facility. The BSL-3 lab provides the extensive security and administrative support structure required for possession of CDC select agents. The laboratory acquires strains of viruses and bacteria, prepares seed stocks, and characterizes these seed stocks using phenotypic and molecular methods to ensure a well-characterized, pure biological reagent. Laboratory staff members assist investigators with experiments involving pathogen culture, fractionation of biological material, animal challenge, and vaccine and drug administration. The laboratory is equipped for commonly used analytical methods, including fluorescence microscopy, PCR, EIA, and ELISPOT. A single suite with both laboratory and experimental animal capability eliminates the need to transport infectious material between laboratories. The BSL-2 laboratory provides support required by the BLS-3 facility, access to attenuated strains exempt from select agent registration, and laboratory space for visiting investigators. Investigators interested in working with the Microbiology and Animal Resources core laboratory should complete the Core A Request Form and send it to Christine Anderson. See lab website for details. There are no charges for projects focused on NIAID priority pathogens and agents of emerging infectious disease.
elispot assay, microscopy, real-time pcr is listed by: Eagle I
is related to: HMS East Quad NMR Core Facility
has parent organization: Harvard Medical School; Massachusetts; USA
nlx_156275 http://nerce.med.harvard.edu/microanimal.html SCR_009807 2026-02-13 10:56:30 0

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