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SciCrunch Registry is a curated repository of scientific resources, with a focus on biomedical resources, including tools, databases, and core facilities - visit SciCrunch to register your resource.
Initiative to enable cancer discovery and treatment based on complete elucidation of molecular networks underlying cancer. CCMI leverages advanced interaction mapping and computational facilities to generate and analyze cancer networks.
Proper citation: Cancer Cell Map Initiative (RRID:SCR_023043) Copy
Medical wiki of interventions, regimens, and general information relevant to fields of hematology and oncology. Knowledge base for hematology and oncology providers, containing details about hematology/oncology drugs and treatment regimens. Any healthcare professional can sign up to contribute. Acuracy and completeness of content is overseen by Editorial Board.
Proper citation: HemOnc Knowledgebase (RRID:SCR_023436) Copy
A research program of the NIA which focuses on neuroscience, aging biology, and translational gerontology. The central focus of the program's research is understanding age-related changes in physiology and the ability to adapt to environmental stress, and using that understanding to develop insight about the pathophysiology of age-related diseases. The IRP webpage provides access to other NIH resources such as the Biological Biochemical Image Database, the Bioinformatics Portal, and the Baltimore Longitudinal Study of Aging., THIS RESOURCE IS NO LONGER IN SERVICE. Documented on September 16,2025.
Proper citation: Intramural Research Program (RRID:SCR_012734) Copy
Precision oncology knowledge base which contains information about the effects and treatment implications of specific cancer gene alterations. OncoKB contains detailed information about specific alterations in 418 cancer genes. Each variant entry contains biological effect, prevalence, prognostic information, and treatment implications. Information is curated from various sources, such as guidelines from the FDA, ClinicalTrials.gov, and scientific literature by a network of clinical fellows, research fellows, and faculty members at Memorial Sloan Kettering Cancer Center.
Proper citation: OncoKB (RRID:SCR_014782) Copy
http://galaxy.cineca.it/fusion/main
Portal provides an easy access to a comprehensive database designed for storing, displaying and annotating gene fusion events detected from NGS data. It can query a database of somatic fusion genes events predicted and annotated starting from paired-end RNA-seq data.
Proper citation: LiGeA (RRID:SCR_015940) Copy
https://www.mitochondriasci.com/mitochondria-related-diseases.html
Creative Biogene provides comprehensive range of services and products to assist researchers in mitochondrial assays and studies. Service to validate and explore pathogenesis of mitochondria associated diseases and possible interventions.
Proper citation: Creative Biogene Mitochondria Related Diseases (RRID:SCR_022080) Copy
Portal to make cancer related proteomic datasets easily accessible to public. Facilitates multiomic integration in support of precision medicine through interoperability with other resources. Developed to advance our understanding of how proteins help to shape risk, diagnosis, development, progression, and treatment of cancer. One of several repositories within NCI Cancer Research Data Commons which enables researchers to link proteomic data with other data sets (e.g., genomic and imaging data) and to submit, collect, analyze, store, and share data throughout cancer data ecosystem. PDC provides access to highly curated and standardized biospecimen, clinical, and proteomic data, intuitive interface to filter, query, search, visualize and download data and metadata. Provides common data harmonization pipeline to uniformly analyze all PDC data and provides advanced visualization of quantitative information. Cloud based (Amazon Web Services) infrastructure facilitates interoperability with AWS based data analysis tools and platforms natively. Application programming interface (API) provides cloud-agnostic data access and allows third parties to extend functionality beyond PDC. Structured workspace that serves as private user data store and also data submission portal. Distributes controlled access data, such as patient-specific protein fasta sequence databases, with dbGaP authorization and eRA Commons authentication.
Proper citation: Proteomic Data Commons (RRID:SCR_018273) Copy
Core facility that provides the following services: Microarray and other genomic data analysis, MiSeq. The Center provides broad-based support for the generation, analysis, and interpretation of genomic and other large-scale data in the context of basic, clinical and translational research. The CCCB has three primary elements. * The CCCB sequencing facility offers a wide range of services to assist in the design and execution of next-generation sequencing projects. Utilizing the Illumina (Solexa) sequencing technology, they currently support a number of applications inlcuding ChIP-Seq, RNA-Seq, whole genome, whole exome, and targeted re-sequencing. * The analytical services and support platform aims to provide state-of-the-art assistance in the collection, management, analysis, and interpretation of large-scale data with a focus on data generated using ''''omic technologies. In addition, they offer software, services, and training designed to assist investigators in advancing their research. * The CCCB research program is focused on development of new methods for improving analysis and interpretation of genomic data through integration of diverse data types with the goal of creating open-source software tools to be made freely-available to the research community.
Proper citation: DFCI Center for Cancer Computational Biology (RRID:SCR_012688) Copy
Biobank provides data collected at Assessment Center and via online questionnaires on participants aged 40-69 years recruited throughout United Kingdom and provides summary information to improve prevention, diagnosis and treatment of serious and life threatening illnesses.
Proper citation: UK Biobank (RRID:SCR_012815) Copy
http://sharedresources.fredhutch.org/core-facilities/antibody-technology
THIS RESOURCE IS NO LONGER IN SERVICE.Documented on July 27,2022. Core facility that provides custom designed monoclonal antibodies made in mice, rats and rabbits. Services include design of antigens, immunization and screening strategies; hybridoma cell line production and optimization; and custom designed antibodies for biomarker discovery.
Proper citation: Fred Hutchinson Cancer Research Center Co-operative Center for Excellence in Hematology Antibody Technology (RRID:SCR_015322) Copy
http://sharedresources.fredhutch.org/core-facilities/experimental-histopathology
THIS RESOURCE IS NO LONGER IN SERVICE. Documented on July 27,2022. Core facility which provides various histology, histochemistry, immunochemistry, and pathology services. They also provide technical training for histopathological methods and tools.
Proper citation: Fred Hutchinson Cancer Research Center Co-operative Center for Excellence in Hematology Experimental Histopathology Shared Resource (RRID:SCR_015329) Copy
http://sharedresources.fredhutch.org/core-facilities/library
THIS RESOURCE IS NO LONGER IN SERVICE. Documented on July 27, 2022. Library that provides physical and digital research resources for Fred Hutchinson's Center in Cancer Research. Physical resources include a library with high-speed internet and computer lab resources as well as access to digital research journals, databases and web services.
Proper citation: Fred Hutchinson Cancer Research Center Co-operative Center for Excellence in Hematology Arnold Library (RRID:SCR_015328) Copy
http://sharedresources.fredhutch.org/core-facilities/specimen-processingresearch-cell-bank
THIS RESOURCE IS NO LONGER IN SERVICE.Documented on July 27,2022. A specimen processing/research cell bank that provides a broad range of services including processing of blood, urine, buccal, peripheral blood mononuclear cells (PBMC); DNA extractions; mycoplasma testing; and DNA fingerprinting for cell line verification. The facility also offers specimen storage options and tissue culture of B cells.
Proper citation: Fred Hutchinson Cancer Research Center Co-operative Center for Excellence in Hematology Specimen Processing/Research Cell Bank (RRID:SCR_015332) Copy
http://sharedresources.fredhutch.org/core-facilities/flow-cytometry
THIS RESOURCE IS NO LONGER IN SERVICE.Documented on July 27,2022. Core facility which offers various options for instrumentation, from single-laser benchtop analyzers to complex multi-laser cell sorts for cell analysis and sorting. Technical assistance is available for the evaluation and interpretation of data as well as assistance in experimental design.
Proper citation: Fred Hutchinson Cancer Research Center Co-operative Center for Excellence in Hematology Flow Cytometry (RRID:SCR_015333) Copy
http://sharedresources.fredhutch.org/core-facilities/electron-microscopy
THIS RESOURCE IS NO LONGER IN SERVICE. Documented on July 27,2022. Core facility that provides transmission electron microscopy and scanning electron microscopy for Fred Hutch, Cancer Consortium and Seattle area researchers. Services include immunogold labeling, negative staining, and a variety of sample preparations including cryo techniques, high pressure freezing (HPF) and automatic freeze substitution (AFS).
Proper citation: Fred Hutchinson Cancer Research Center Co-operative Center for Excellence in Hematology Electron Microscopy (RRID:SCR_015330) Copy
http://sharedresources.fredhutch.org/core-facilities/glassware-services
THIS RESOURCE IS NO LONGER IN SERVICE.Documented on July 27,2022. Core facility that provides cleaning and sterilization of reusable laboratory glassware. Services include washing, drying and sterilization of glassware, pipette plugging and autoclaving of laboratory liquids. The core also provides support for operation of media services and biohazardous waste processing.
Proper citation: Fred Hutchinson Cancer Research Center Co-operative Center for Excellence in Hematology Glassware Services (RRID:SCR_015331) Copy
http://sharedresources.fredhutch.org/core-facilities/research-freezers-and-sample-storage
THIS RESOURCE IS NO LONGER IN SERVICE. Documented on July 27,2022. Core facility that provides space for freezers used to store research samples, offers assistance with evaluating the space and power needs for new freezers, provides information on best practices, and provides access and allocates space in the shared freezer facility.
Proper citation: Fred Hutchinson Cancer Research Center Co-operative Center for Excellence in Hematology Research Freezers and Sample Storage Resource (RRID:SCR_015334) Copy
http://sharedresources.fredhutch.org/core-facilities/proteomics
THIS RESOURCE IS NO LONGER IN SERVICE.Documented on July 27,2022. Core facility that provides support for characterizing proteins and peptides by mass spectrometry and high-performance liquid chromatography.
Proper citation: Fred Hutchinson Cancer Research Center Co-operative Center for Excellence in Hematology Proteomics Resource (RRID:SCR_015335) Copy
http://www.umassmed.edu/cancercenter/tissuebank/index.aspx
The UMass Cancer Center Tissue and Tumor Bank is a dynamic tissue procurement service: Collection, Storage, Annotation, and Distribution of Human Biologic Specimens. Our goal is to facilitate basic science, clinical research and translational studies by providing researchers with the ability to obtain and study human tissues using a dynamic collection, storage, annotation, and distribution service. * Fresh, diseased tissue is collected and processed immediately after surgery. ** When possible, surrounding healthy tissue is collected as a matched normal control. ** Anonymous, de-identified clinical and pathologic data are linked to the specimens in a secure database. * Bone marrow and blood specimens are collected and available as fresh cell isolates, frozen cell isolates or unprocessed. * A variety of services are available including routine histology, fresh tissue for cell culture, frozen sections, as well as DNA and RNA extraction. * Specific study needs can be met. * Consultation during study design is available and recommended. Contact Us * Assistance in the IRB approval process is offered. ** New: IRB approval is required only if you need identifiable private clinical information and/or patient follow-up for your study. The UMass Cancer Center Tissue and Tumor Bank is an open access biorepository. Specimens are available to investigators both internal and external to UMass. The Tumor Bank ships specimens to researchers worldwide. Please contact us to determine if we have specimens that meet your research needs.
Proper citation: UMass Cancer Center Tissue and Tumor Bank (RRID:SCR_004447) Copy
THIS RESOURCE IS NO LONGER IN SERVICE. Documented on January 9, 2023. In this web site you will find the central European database of OECI-TuBaFrost collecting the information of biobanks or in the project support environment on human material; i.e., frozen tumor tissue specimens, pathology blocks, blood samples in different forms, cell lines, Tissue Micro Arrays, etc. Our goal is by centralizing the tumor tissues information to facilitate the search of doctors / researchers for tumor materials, which they need for their cancer research there with facilitating cancer research. OECI members only can participate in the OECI-TuBaFrost exchange platform, or those introduced by an OECI member. We are a group of pathology and research departments as well as bio-bankers in clinical based biobanking based in comprehensive cancer centers or hospitals with a competence in comprehensive cancer care across Europe. Each participating institute is involved in cancer research resulting in innovative procedures, new drugs, improved diagnosis and new insights in disease development. The overall result is better care and treatment for cancer patients. To maximize the scientific value of the human tissue samples, information about the clinical status of the patient in combination with the quality and type of samples is very important. A TuBaFrost electronic database will securely store all this information. Within the closed project supporting environments, the data collected will include: * Diagnosis - identification of the type of cancer * Type of tissue collected - the origin, i.e. breast, skin, colorectal * Quality of tissue collected - collection and storage details The tissue is stored in the hospital where the donor was diagnosed/treated. It stays there until it is used or sent to another hospital or research center within the TuBaFrost group. The electronic database will track samples throughout the network. The tissue is not sold. The exchange of tissue to other hospitals is regulated by a contract, which uses the national regulations of the country supplying the tissue. Tissue samples within the TuBaFrost collection will only be used for research, which has been approved by ethics committees. This ensures that the tissue is only used for the best quality research and only for the specific reasons given to the ethics committee.
Proper citation: OECI - Tubafrost: The European Human Frozen Tissue Bank (RRID:SCR_004280) Copy
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