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SciCrunch Registry is a curated repository of scientific resources, with a focus on biomedical resources, including tools, databases, and core facilities - visit SciCrunch to register your resource.
http://www.sph.umich.edu/csg/yli/whait/
THIS RESOURCE IS NO LONGER IN SERVICE. Documented on September 23,2022. Software application (entry from Genetic Analysis Software).
Proper citation: WHAIT (RRID:SCR_009425) Copy
http://www.molecular-haplotype.org/zaplo/zaplo_index.html
THIS RESOURCE IS NO LONGER IN SERVCE, documented September 6, 2016.
Proper citation: ZAPLO (RRID:SCR_009426) Copy
https://github.com/gaow/genetic-analysis-software/blob/master/pages/UNKNOWN.md
Software application (entry from Genetic Analysis Software)
Proper citation: UNKNOWN (RRID:SCR_009423) Copy
http://faculty.washington.edu/browning/presto/presto.html
THIS RESOURCE IS NO LONGER IN SERVICE. Documented on June 1, 2023. Software application that calculates individual inbreeding (F) and average relatedness (AR) coefficients. Additionally, users can compute useful parameters in population genetics such as: the number of ancestors explaining genetic variability; the genetic importance of the herds; F statistics from genealogical information. (entry from Genetic Analysis Software)
Proper citation: ENDOG (RRID:SCR_013289) Copy
http://wpicr.wpic.pitt.edu/WPICCompGen/fdr/
Software application (entry from Genetic Analysis Software)
Proper citation: WEIGHTED FDR (RRID:SCR_013442) Copy
http://faculty.washington.edu/browning/beaglecall/beaglecall.html
Software package for simultaneous genotype calling and haplotype phasing for unrelated individuals. BEAGLECALL produces output posterior genotype probabilities and output phased haplotypes. BEAGLECALL generates extremely accurate genotype calls because it uses both allele signal intensity data and inter-marker correlation to call genotypes. BEAGLECALL is designed for use with high-density SNP arrays, and it uses the BEAGLE haplotype frequency model to model inter-marker correlation. (entry from Genetic Analysis Software)
Proper citation: BEAGLECALL (RRID:SCR_013301) Copy
Software application for performing genome scan meta-analysis, a quantitative method to identify genetic regions (bins) with consistently increased linkage score across multiple genome scans, and for testing the heterogeneity of the results of each bin across scans. The program provides as an output the average of ranks and three heterogeneity statistics, as well as corresponding significance levels. (entry from Genetic Analysis Software)
Proper citation: HEGESMA (RRID:SCR_013304) Copy
Software application (entry from Genetic Analysis Software)
Proper citation: PYPOP (RRID:SCR_013425) Copy
http://www.multifactordimensionalityreduction.org/
Software application that is a data mining strategy for detecting and characterizing nonlinear interactions among discrete attributes (e.g. SNPs, smoking, gender, etc.) that are predictive of a discrete outcome (e.g. case-control status). The MDR software combines attribute selection, attribute construction and classification with cross-validation to provide a powerful approach to modeling interactions. (entry from Genetic Analysis Software)
Proper citation: MDR (RRID:SCR_013427) Copy
http://lbm.ab.a.u-tokyo.ac.jp/~iwata/antmap/
Software application based on the Ant Colony Optimization to solve the special case of the traveling salesman problem of ordering markers when the number of loci is large. ANYMAP performs segregation test, linkage grouping and locus ordering, and constructs a linkage map rapidly. (entry from Genetic Analysis Software)
Proper citation: ANTMAP (RRID:SCR_013426) Copy
Publicly available Web-based application that can perform QTL mapping on a variety of population types. GridQTL will extend the functionality of QTLExpress by adding new and advanced approaches for modelling QTL analysis in simple and complex populations. These new methods will be available on a Grid system that will offer flexible workflow management, resource allocation, data persistence, detached execution of simulations and the scalability required for the increase in data volume, data sources and complexity required by the new models. (entry from Genetic Analysis Software)
Proper citation: GRIDQTL (RRID:SCR_013397) Copy
http://vipbg.vcu.edu/vipbg/trimhap//
Software application for linkage disequilibrium mapping based on ancestral founder haplotypes. Method uses haplotype data from general pedigrees. (entry from Genetic Analysis Software)
Proper citation: TRIMHAP (RRID:SCR_013512) Copy
http://www.bio.unc.edu/faculty/vision/lab/mappop/
Software application that selects high resolution mapping subsamples and performs bin mapping (entry from Genetic Analysis Software)
Proper citation: MAPPOP (RRID:SCR_013490) Copy
http://dlin.web.unc.edu/software/SNPMStat/
A command-line program for the statistical analysis of SNP-disease association in case-control/cohort/cross-sectional studies with potentially missing genotype data. SNPMStat allows the user to estimate or test SNP effects and SNP-environment interactions by maximizing the (observed-data) likelihood that properly accounts for phase uncertainty, study design and gene-environment dependence. For SNPs without missing data, the program performs the standard association analysis. For typed SNPs with missing data or untyped SNPs, the program performs the maximum-likelihood analysis. (entry from Genetic Analysis Software)
Proper citation: SNPMSTAT (RRID:SCR_013339) Copy
http://www.cbil.ece.vt.edu/ResearchOngoingSNP.htm
Software application (entry from Genetic Analysis Software)
Proper citation: MECPM (RRID:SCR_013341) Copy
http://www.bios.unc.edu/~lin/software/MAOS/
Software application that implements valid and efficient statistical methods for meta-analysis of genomewide association studies with overlapping subjects. The current release performs logistic regression analysis of individual level data under the additive mode of inheritance. Data from genome-wide association studies are often analyzed jointly for the purposes of combining information from multiple studies of the same disease or comparing results across different disorders. In many instances, the same subjects appear in multiple studies. Failure to account for overlapping subjects can greatly inflate type I error when combining results from multiple studies of the same disease and can drastically reduce power when comparing results across different disorders. (entry from Genetic Analysis Software)
Proper citation: MAOS (RRID:SCR_013351) Copy
Center that imports, archives, maintains, and distributes mutant mouse alleles as live mice, frozen germplasm, stem cells, and molecular vectors for use in biomedical research. The MMRRC Davis receives transgenics, knockouts, and other kinds of mutant mouse lines at no cost to the donor, and after re-derivation and cryopreservation, distributes breeding stock, germplasm, cells, or tissues of genetically-defined and pathogen-free mice for a small fee to requesting investigators.
Proper citation: University of California at Davis Mutant Mouse Resource and Research Center (RRID:SCR_016448) Copy
http://www.mmrrc.missouri.edu/
Center that supplies mice and conducts research projects focused on the role of mice as animal models. Some of these projects include refinement of models to ensure study reproducibility, as well as development and improvement of economical methods for cryopreservation of mouse strains.
Proper citation: Mutant Mouse Resource and Research Center - University of Missouri (RRID:SCR_016447) Copy
https://github.com/EpistasisLab/ReBATE
Open source software Python package to compare relief based feature selection algorithms used in data mining. Used for feature selection in any bioinformatics problem with potentially predictive features and target outcome variable, to detect feature interactions without examination of all feature combinations, to detect features involved in heterogeneous patterns of association such as genetic heterogeneity .
Proper citation: ReBATE (RRID:SCR_017139) Copy
http://www.vet.upenn.edu/research/core-resources-facilities/referral-center-for-animal-models
Center that aims to discover, characterize, maintain breeding colonies, and make available dog and cat models with hereditary diseases homologous to those found in human patients that can be used to translate preclinical trials from kennel to clinic. The animal models represent true orthologs of their respective human disease, involving defects in homologous genes resulting in similar molecular, biochemical, pathological, and clinical phenotype as in human patients.
Proper citation: Referral Center for Animal Models of Human Genetic Diseases (RRID:SCR_016453) Copy
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