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SciCrunch Registry is a curated repository of scientific resources, with a focus on biomedical resources, including tools, databases, and core facilities - visit SciCrunch to register your resource.
http://www.hopkinsmedicine.org/diabetes-research-center/research-cores/healthcare-population.html
THIS RESOURCE IS NO LONGER IN SERVICE. Documented on August 9,2024. Contains description of and contact information for multiple health and social science departments.
Proper citation: Johns Hopkins University - University of Maryland Diabetes Research Center Health and Populations Science Core (RRID:SCR_015093) Copy
https://diabetescenters.org/cores/ucsd-ucla-genomics-and-epigenetics-core
Core which provides Diabetes Research Center investigators access to high-throughput sequencing, data acquisition and analysis. Its main services include Sample QC and Processing, Illumina Platform Library Preparation and Sequencing, and Expression microarrays (RNA, microRNA).
Proper citation: University of California San Diego - University of California Los Angeles Diabetes Research Center Genomics and Epigenetics Core Facility (RRID:SCR_015097) Copy
http://depts.washington.edu/diabetes/viral-vector-and-transgenic-mouse/
Core facility that provides Diabetes Research Center affiliates with vectors necessary to overexpress, knockdown, knockout, or alter expression of RNAs and proteins of interest in cultured cells, isolated tissues, and animals.
Proper citation: University of Washington Diabetes Research Center Vector and Transgenic Mouse Core (RRID:SCR_015130) Copy
Core facility that provides the powerful tools of modern mass spectrometry and complex data set analysis to Diabetes Research Center investigators to permit structural identification and quantitation of proteins involved in diabetes and its complications.
Proper citation: University of Washington Diabetes Research Center Quantitative and Functional Proteomics Core Facility (RRID:SCR_015131) Copy
https://diabetescenters.org/cores/ucsd-ucla-metabolic-and-molecular-physiology-core
Provides DRC investigators with thorough scientific consultation and timely, accurate, and easily accessible mouse, tissue, and cellular phenotyping. Services include whole animal, tissue and cellular metabolism, insulin action, and inflammatory signaling as well as cardiac, vascular and renal phenotyping associated with diabetes complications research. It also administers drugs and other substances to mice by different routes in a well-controlled setting.
Proper citation: University of California San Diego - University of California Los Angeles Diabetes Research Center Metabolic and Molecular Physiology Core Facility (RRID:SCR_015095) Copy
Core facility whose services include histology, immunohistochemistry, RNA in situ hybridization, mRNA probe generation, frozen sections for enzyme histochemistry, immunofluorescent antibody studies, live and fixed cell confocal, deconvolution microscopy and super resolution microscopy (SIM and STORM), and transmission electron microscopy, quantitative morphometric analysis, high throughput microscopy and high content analysis, laser capture microdissection for molecular genetic analyses, and digital images for internet communication and publication.
Proper citation: Texas Medical Center Digestive Diseases Center Cellular and Molecular Morphology Core (RRID:SCR_015219) Copy
Core that provides epidemiological and biostatistical support for design and analysis, and also provides investigators with access to the clinical specimens required for their basic and translational research activities. It offers assistance as well as didactic training in issues involving local and foreign IRB?s, HIPPA regulations, and importing or exporting clinical specimens.
Proper citation: Texas Medical Center Digestive Diseases Center Study Design and Clinical Research Core Services (RRID:SCR_015218) Copy
http://cihd.cores.utah.edu/mgd/
Core facility which provides custom TALEN and Crispr-Cas9 DNA nucleases to induce targeted mutations in a genomic region of interest. It also provides hardware, reagents, and expertise for optimizing and performing HRMA for genes of interest.
Proper citation: Center for Iron and Heme Disorders at the University of Utah Mutation Generation and Detection Core (RRID:SCR_015339) Copy
http://animalcare.umich.edu/business-services/germ-free-mouse-facility
Core that provides services to the University of Michigan community and can also ship germ-free mice to locations worldwide. Its projects include studies investigating inflammatory bowel disease and cancer, host microbiome interactions, infectious disease pathogenesis, and mammalian and bacterial metabolism.
Proper citation: MMPC-University of Michigan Medical School Animal Care and Germ-Free Mouse Core (RRID:SCR_015344) Copy
https://www.bcm.edu/research/centers/digestive-disease/core-facilities/integrative-biology
Core that aims to provide turnkey access to organoids/enteroid technologies to TMC-DDC researchers. These include samples (enteroids, organoids), reagents (specialized growth media, etc.), training, and consultative expertise. The core also provides access to gnotobiotic facilities and animals, training and consultative expertise.
Proper citation: Texas Medical Center Digestive Diseases Center Integrative Biology Core (RRID:SCR_015220) Copy
http://medicine.iupui.edu/ICBM
Core facility which provides access to and training on optical microscopy instruments to Indiana University researchers.
Proper citation: Indiana University Cooperative Center of Excellence in Hematology Optical Microscopy Core (RRID:SCR_015347) Copy
http://www.massgeneral.org/csibd/cores/clinical.aspx
Core whose objective is to provide an infrastructure that facilitates the translation of basic research findings into the clinic. Its services include consultation, training, and education, biospecimen services, and facilitating data collection and analysis.
Proper citation: Center for the Study of Inflammatory Bowel Disease Clinical Core (RRID:SCR_015227) Copy
http://www.cancer.iu.edu/research-trials/facilities/angiobiocore/index.shtml
Core facility which conducts validated and reproducible in vitro and in vivo angiogenesis, endothelial, hematopoietic and multi-parametric flow cytometry assays and their role in normal and patient-related hematologic and cardiovascular disorders.
Proper citation: Indiana University Cooperative Center of Excellence in Hematology Angiogenesis Core (RRID:SCR_015345) Copy
http://www.cancer.iu.edu/research-trials/facilities/flow-cytometry/index.shtml
Core facility which provides flow cytometry consultation, technical advice, flow cytometric analysis and cell sorting services as well as flow cytometric image analysis.
Proper citation: Indiana University School of Medicine Flow Cytometry Core Facility (RRID:SCR_015346) Copy
http://sharedresources.fredhutch.org/core-facilities/scientific-imaging
THIS RESOURCE IS NO LONGER IN SERVICE.Documented on July 27,2022. Scientific imaging service that serves as a centralized facility for imaging and visualization. The core facility provides access to time lapse and 3-D microscopy and quantitative autoradiography.
Proper citation: Fred Hutchinson Cancer Research Center Co-operative Center for Excellence in Hematology Scientific Imaging (RRID:SCR_015340) Copy
http://www.massgeneral.org/csibd/cores/morphology.aspx
Core that provides CSIBD investigators with the technical support, expertise and access to instrumentation necessary for their morphological and cell biological studies related to IBD. These services include routine tissue fixation and processing for light microscopy, imaging flow cytometry, perfusion-fixation of organs, conventional electron microscopy, low temperature embedding in Lowicryl HM20, and immunocytochemistry.
Proper citation: Center for the Study of Inflammatory Bowel Disease Morphology Core (RRID:SCR_015228) Copy
http://medicine.yale.edu/labmed/ycceh/cores/core_d/index.aspx
Core facility which provides expertise, technical assistance, and mice for human-into-mouse xenotransplantation studies. Mouse models include MITRG-SKI (KnockIn) mice that express human cytokines and huSIRPa from the endogenous murine loci in the Rag-/- IL-2Ry -/- background. It also offers training and technical assistance in the study of hematopoiesis and benign hematologic questions in mice.
Proper citation: Yale Cooperative Center of Excellence in Hematology Animal Modeling Core (RRID:SCR_015349) Copy
Core facility which supports faculty research by facilitating access to human biospecimens. Its services include centralized access to participating Mayo Clinic GI biobanks and other institutional biospecimen resources, de-identified, phenotypic and demographic data, and coordination of fresh tissue acquisition from surgical pathology.
Proper citation: Mayo Clinic Center for Cell Signaling in Gastroenterology Clinical Core (RRID:SCR_015229) Copy
https://keck.usc.edu/liver-diseases-research-center/about-the-center/scientific-cores/
Core facility which provides primary hepatocytes cultures of normal and diseased mice and rats and various cell lines to investigators. The cell separation subcore plays a role in translational research in DILI and alcoholic hepatitis, supporting funded studies of the role of innate and adaptive immune systems in elucidating pathophysiology, identifying biomarkers, and predicting response to treatments.
Proper citation: USC Liver Transplant Program and Center for Liver Disease Cell Separation and Culture Core (RRID:SCR_015233) Copy
http://cure.med.ucla.edu/cores/administrative
Management core that develops mission, goals, and strategies relating to the functioning of the CURE:DDRCC.
Proper citation: CURE - Digestive Diseases Research Center Administrative Core (RRID:SCR_015231) Copy
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