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http://harvard.eagle-i.net/i/0000012a-2517-32d8-5617-794280000000

Core facility that provides the following services: DNA injection service, Embryonic stem cell injection service, Transgenic mouse line rescue service, Transgenic mouse embryo handling services, Mouse assisted reproductive services.

The Beth Israel Deaconess Transgenic Core Facility opened in October of 1991.The Transgenic Core is a state-of-art facility that produces genetically altered animals.

Proper citation: BIDMC Transgenic Core Facility (RRID:SCR_009677) Copy   

•   Source: SciCrunch Registry

http://harvard.eagle-i.net/i/0000012b-00c4-d136-db6e-7a3f80000000

Core facility that provides the following services: In Vivo Magnetic Resonance Imaging (MRI), Quantitative Image Analysis: Standard Uptake Value (SUV), 3D Volume Measurements, Animal Handling Techniques: Blood Collection, Injections (IV, IP), Oral Gavage, Tumor Inoculation, Transcardiac Perfusion, etc., Whole-body and Tissue Cryosectioning, Ex Vivo Tissue Radioactivity Measurement.

Our goal is to provide state-of-the-art small animal imaging services to researchers in the Longwood Medical Area of Harvard Medical School. These services include multi-modality imaging, advanced data analysis, image fusion resources, and a satellite animal facility for longitudinal studies. A detailed description of our instruments and services are provided on our website, and we welcome questions and comments.

Proper citation: BIDMC Longwood Small Animal Imaging Core Facility (RRID:SCR_009670) Copy   

•   Source: SciCrunch Registry

http://harvard.eagle-i.net/i/0000012a-2513-da28-5617-794280000000

Core facility that provides the following services: Imaging consultation service, Image analysis service. The CRL was formed with the mission of improving our understanding of the structure and function of the brain and other organs of the human body, in order to improve our capacity to diagnose and treat disease. Members of the CRL achieve this by developing novel technologies and computational modeling strategies for understanding and interpreting radiological images.

Proper citation: CHB Computational Radiology Laboratory (RRID:SCR_009709) Copy   

•   Source: SciCrunch Registry

http://cdrewu.eagle-i.net/i/00000135-ca50-bd65-1a88-e81c80000000

The Vivarium is a facility dedicated to the humane care and use of laboratory animals.

Proper citation: CDU Vivarium (RRID:SCR_009704) Copy   

•   Source: SciCrunch Registry

http://harvard.eagle-i.net/i/0000012e-5db0-d3b1-55da-381e80000000

Core facility that provides the following services: Advanced ultrasound imaging. The mission of the Advanced Fetal Care Center (AFCC) is to provide the finest diagnosis and care for a mother carrying a baby with a congenital anomaly. For these families, our center offers entry to a continuum of care and support that extends throughout childhood--from prenatal diagnosis and counseling, through treatment and long-term follow-up. On rare occasions, our team will recommend and perform intervention during fetal life. Our physicians, who represent all pediatric subspecialty areas, work with a wide range of babies with anomalies. Together, they have developed ground-breaking procedures in fetal medicine and surgery.

Proper citation: CHB Advanced Fetal Care Center (RRID:SCR_009705) Copy   

•   Source: SciCrunch Registry

http://cdrewu.eagle-i.net/i/00000135-20b7-3e29-f836-7d1b80000000

Core facility that provides the following services: Morphometric study design, Tissue embedding and sectioning service, Tissue embedding, sectioning and microscopy training. The Morphometry and Stereology Laboratory is a service and training laboratory for the faculty, students, and staff of CDU and other interested researchers. The mission of the laboratory is to: 1) teach up-to-date stereology theory and practical morphometric techniques; 2) help design unbiased efficient morphometric studies; 3) train researchers to use the equipment and software available in the laboratory; 4) develop an outreach program for community students to visit a microscopy research laboratory; 5) organize stereology workshops for CDU personnel and other interested researchers.

Proper citation: CDU Morphometry and Stereology Laboratory (RRID:SCR_009703) Copy   

•   Source: SciCrunch Registry

http://harvard.eagle-i.net/i/0000012a-2518-fb6c-5617-794280000000

THIS RESOURCE IS NO LONGER IN SERVICE. Documented on October 27, 2023. Core provides services: RT PCR service, Gene expression profiling service, Proteomics analysis service, Bioinformatics and Systems Biology analyses, Next Generation Sequencing Service, Affymetrix Human and Mouse Gene 2.0 ST Arrays and 2.1 ST Arrayplates. Core proteomics facility for the Dana-Farber/Harvard Cancer Center. Workflows and algorithms for analysis of next-generation sequencing data including RNA-Seq, ChIP-Seq, Epigenetics-Seq and DNA seq, Comprehensive workflow for analysis of Microbiome sequencing data, Integrated systems biology analysis of transcriptome, miRNA, epigenome, metabolomics and proteomics data. Pipelines: MALDI Tissue imaging and targeted quantitative proteomics.

Proper citation: Beth Israel Deaconess Medical Center Genomics Proteomics Bioinformatics and Systems Biology Center (RRID:SCR_009668) Copy   

•   Source: SciCrunch Registry

http://harvard.eagle-i.net/i/0000012e-6cd0-f03d-55da-381e80000000

Core facility that provides the following services: Cell sorting service.

The Department of Pathology Flow Cytometry Facility provides flow cytometric analysis and cell sorting services to investigators in the Harvard Medical School and in the Harvard affiliated hospitals and institutions. The facility currently has a FACSCalibur for assisted as well as unassisted flow cytometric acquisition and analysis, and a FACSAria for cell sorting (performed by an expert technician).

Proper citation: HMS Flow Cytometry Facility (RRID:SCR_009666) Copy   

•   Source: SciCrunch Registry

http://harvard.eagle-i.net/i/0000012a-2517-523f-5617-794280000000

Partially funded through Harvard Catalyst, the Clinical Research Coordinator Core is available to support and collaborate with investigators and their research teams in all phases of clinical research, providing services that include assisting with the organization, implementation and completion of clinical research studies.

Proper citation: BIDMC Clinical Research Coordinator Core Laboratory (RRID:SCR_009663) Copy   

•   Source: SciCrunch Registry

http://harvard.eagle-i.net/i/00000143-6d42-d9ec-0803-96bd80000000

Core facility that provides the following services: Fluorescence activated cell sorting, Data analysis and interpretation.

Cytometry and cell sorting core at the Center for Virology and Vaccine Research. The facility has a BD FACSAria II housed in a sterile biosafety cabinet in a BSL2+ facility, allowing sorting of unfixed, live cells into a variety of tubes and plates. Equipment, consultation, dedicated operator, and data analysis available to outside researchers. To schedule an appointment, please fill out and submit the Investigator Sort Form available on our website or contact us below.

Proper citation: BIDMC CVVR Flow Cytometry Core (RRID:SCR_009661) Copy   

•   Source: SciCrunch Registry

http://eagle-i.ea.vanderbilt.edu/i/00000139-a24f-c60a-b4bd-8a1180000000

This core facility can assist with measurements of reactive oxygen species, nitric oxide, and assist in measurements of vascular reactivity for investigators in the Vanderbilt community. The FRIMCORE employs state of the art methods, including electron spin resonance, fluorescent techniques and HPLC (High-Performance Liquid Chromatography) for measurement of reactive oxygen species and nitric oxide in cells and tissues.

Proper citation: Vanderbilt Free Radicals in Medicine Core (RRID:SCR_009541) Copy   

•   Source: SciCrunch Registry

https://www.baderc.org/cores/metaboliccore/

Core in BADERC that provides services in consultation and teaching, use of DEXA scanner for determination of body fat and/or bone density, and use of Coulter Counter to measure cell number and cell size distribution.

Proper citation: Boston Area Diabetes Endocrinology Research Center Metabolic Physiology and Energy Balance Core Facility (RRID:SCR_008293) Copy   

•   Source: SciCrunch Registry

http://harvard.eagle-i.net/i/0000012a-251a-2c19-5617-794280000000

The mission of the Biomedical Research Informatics Core (BRIC) is to utilize the expertise of BIDMC ''informaticians'' with backgrounds in medicine, biology, engineering, biostatistics, and computer science to facilitate research at our institution by (a) providing a high level of service and experience in informatics that is difficult for individual laboratories to achieve and maintain, (b) developing the infrastructure required to address common informatics needs of all researchers, and (c) identifying areas in which there can be closer collaboration among life scientists and quantitative scientists. View our portfolio for examples of BRIC projects. To arrange for a free consultation, please contact Griffin Weber. If you choose to use BRIC services, hourly fees vary depending on the types of services needed. You will be given an estimate of the number of hours before any work begins.

Proper citation: BIDMC Biomedical Research Informatics Core Laboratory (RRID:SCR_009660) Copy   

•   Source: SciCrunch Registry

http://dartmouth.eagle-i.net/i/0000012b-00c3-e398-6a59-ec4e80000000

Core facility that provides the following services: Custom design and development of equipment, tools and instruments for scientific research.

Proper citation: Dartmouth Department of Physics: Apparatus Shop Core Laboratory (RRID:SCR_009738) Copy   

•   Source: SciCrunch Registry

http://harvard.eagle-i.net/i/0000012e-7276-7824-55da-381e80000000

Core facility that provides the following services: Whole genome amplification service, Genotyping service using Illumina GoldenGate and Infinium technologies, SNP Analysis using OpenArray Genotyping, SNP Analysis using Taqman, Custom Illumina GoldenGate genotyping, Illumina Infinium genotyping.

The mission of the High-Throughput Polymorphism Detection Core is to provide services to investigators conducting molecular analyses of somatic DNA collected as part of a wide range of investigations. This Core provides high-throughput assays of specific gene mutations and polymorphisms (SNPs) in the many situations where previously defined specific nucleotide alterations are of interest.

Proper citation: DF/HCC High-Throughput Polymorphism Detection Core (RRID:SCR_009736) Copy   

•   Source: SciCrunch Registry

http://harvard.eagle-i.net/i/0000012d-c90c-c8fc-4882-b08d80000000

Core facility that provides the following services: Hematopoietic progenitor cell (HPC) components processing, Tumor cell vaccine generation, Dendritic cell vaccine generation, Validation consultation.

The (Connell and O''Reilly Families) Cell Manipulation Core Facility (CMCF), at Dana-Farber Cancer Institute (DFCI) was created in 1996 to be the manufacturing facility that produces safe and effective novel cellular component therapy that meets regulatory guidelines for clinical use and also facilitates research to be translated from the bench to the bedside. The goal of this facility is to assist DF/HCC investigators in developing new cell-based therapies for cancer and to support clinical research studies designed to evaluate the toxicity and efficacy of these novel treatments. In November 2004, CMCF moved to a newly constructed 6,700 square feet facility on the third floor and ground floor of the Jimmy Fund Building (JFB) at DFCI. The new facility is dedicated to the production of clinical grade cellular products for patients who participate in clinical trials conducted by DF/HCC investigators. All procedures are performed in environmentally controlled conditions according to current Good Manufacturing Practices (cGMP) for cell and tissue processing. The third floor accommodates all of the production areas while space on the ground floor is devoted to the long-term storage of cellular products, tissues and samples in liquid nitrogen and mechanical freezers. The CMCF is available to both clinical and laboratory investigators at all DF/HCC institutions and will provide services to patients at all DF/HCC affiliated hospitals. The staff of the CMCF are committed to working with DF/HCC investigators at all levels of clinical trial development and execution, including pre-clinical development, trial design, DF/HCC and FDA review, data management, quality control, internal and external audits as well as reports and publications. The Cell Manipulation Core Facility (CMCF) has been accredited by the Foundation for the Accreditation of Cellular Therapy (FACT). The CMCF services as a Regulatory Core for Center for Human Cell Therapy and is also a member of the Joint Program in Transfusion Medicine.

Proper citation: DF/HCC Cell Manipulation Core Facility (RRID:SCR_009734) Copy   

•   Source: SciCrunch Registry

http://harvard.eagle-i.net/i/0000012e-a1a6-4291-55da-381e80000000

Core facility that provides the following services: Progamming and sequencing classes and training. Research Computing (RC) facilitates the advancement of complex research by providing leading edge computing services across the Faculty of Arts & Sciences (FAS). RC staff maintain expertise in constantly changing computing technologies, while ''speaking the language'' of the FAS researchers, to help them use computing more effectively.

Proper citation: Harvard FAS Research Computing Core (RRID:SCR_009844) Copy   

•   Source: SciCrunch Registry

http://harvard.eagle-i.net/i/0000012f-e9eb-c410-de5a-673e80000000

The Neuroimaging facility has a 3-Tesla magnetic resonance imaging scanner for non-invasive human brain imaging. Our aim is to: * Provide functional and anatomic magnetic resonance imaging (MRI) to scientists studying human cognition, brain development and aging, and individual differences * Provide training for undergraduate and graduate students destined to become the next generation of neuroscientists * Pioneer innovative ways of imaging the human brain and is a first adopter of new neuroimaging technology, tools and applications * Develop and make available the data processing and visualization tools demanded by advancing neuroimaging technologies.

Proper citation: Harvard FAS Center for Brain Science - Neuroimaging Core Facility (RRID:SCR_009842) Copy   

•   Source: SciCrunch Registry

http://harvard.eagle-i.net/i/0000012f-e9ed-31bd-de5a-673e80000000

CBS hosts an optical imaging facility that houses advanced devices for widespread use by neuroscientists and is developing the next generation of optical techniques. The optical imaging is intended to be an extension of individual labs, housed in shared space. By pooling equipment, highly skilled technical management of the tools is available, allowing for routine technological upgrades, quicker troubleshooting, and expert advice. In addition, the joint space leads to camaraderie amongst users, and allows new technical advances in one lab to spread rapidly to other labs. This core facility also frees up space in individual labs that can be used in other ways. Finally, the shared equipment lowers barriers to adoption of the latest technology. This core facility provides: * Laser scanning microscopes with motorized stages for high throughput reconstructions of the nervous system * A histology suite for brain sectioning and tissue preparation * Stereo fluorescence macroscopes * The newest tools for high-resolution optical microscopy * Ultra-fast optical scanning microscopes

Proper citation: Harvard FAS Center for Brain Science - Imaging Core Facility (RRID:SCR_009840) Copy   

•   Source: SciCrunch Registry

http://harvard.eagle-i.net/i/0000012f-e9f0-3cf3-de5a-673e80000000

CBS houses a core facility with a transmission electron microscope (TEM) and several scanning electron microscopes. The SEMs are part of ongoing research that will lead to a three-dimensional electron microscopy facility, to image neural circuits with the highest possible resolution.

Proper citation: Harvard FAS Center for Brain Science - Electron Microscopy Core Facility (RRID:SCR_009838) Copy   

•   Source: SciCrunch Registry