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SciCrunch Registry is a curated repository of scientific resources, with a focus on biomedical resources, including tools, databases, and core facilities - visit SciCrunch to register your resource.
Core specializes in small molecule analysis. Services include, but are not limited to, quantitative mass spectrometry, liquid chromatography separations, fragmentation and structural elucidation mass spectrometry, complex mixture analysis, molecular formula confirmation, high resolution and accurate mass analysis.Provides individualized user training for undergraduate, graduate, and post-doctoral scholars of Department of Chemistry.
Proper citation: University of North Carolina at Chapel Hill Department of Chemistry Mass Spectrometry Core Facility (RRID:SCR_021937) Copy
Provides optical and electron microscope infrastructure for live cell imaging, multi photon imaging, advanced sample preparation including cryo-preparation for electron microscopy, routine SEM and TEM, Cryo-TEM, TEM tomography, and Correlative Light and Electron Microscopy (CLEM). Equipped with 4 electron microscopes (1 SEM and 3 TEMs), 2 advanced fluorescence microscopes (confocal/multi-photon and spinning disk), cryo-fixation (High pressure freezer, Vitrobot) and EM processing equipment (Microwave, critical point dryer, coaters).Provides microscopy access, training and service.
Proper citation: University of British Columbia Vancouver Bioimaging Core Facility (RRID:SCR_021304) Copy
https://www.biotech.cornell.edu/core-facilities-brc/facilities/bioinformatics-facility
Facility provides access to high performance computing environment, BioHPC, which includes both hosted hardware and shared machines. Provides consulting and collaborations for Bioinformatics analysis and workflows.
Proper citation: Cornell University BRC Bioinformatics Core Facility (RRID:SCR_021757) Copy
https://www.research.colostate.edu/arc/
Core is comprised of Materials and Molecular Analysis (MMA), Imaging and Surface Science (ISS), and Bioanalysis and Omics (BIO) centers. MMA provides instrument capabilities and expertise in spectroscopic (optical, NMR, EPR), mass spectrometry, X-ray and materials (magnetic, thermal, physical) characterization of synthetic, environmental and biological materials, both at bulk and molecular scales; BIO provides analysis of complex biological samples using modern mass spectrometry based metabolomics and proteomics approaches, including supporting cheminformatics; ISS provides analysis of complex biological and inorganic samples using near and far field imaging methods, spectroscopy, and other surface analyses.
Proper citation: Colorado State University Analytical Resources Core Facility (RRID:SCR_021758) Copy
https://www.uhcancercenter.org/research/shared-resources/microscopy-imaging-and-flow-cytometry
Core offers optical analysis instrumentation from specialized light microscopes to bioluminescence preclinical imagers to flow cytometers for multicolor cellular analysis. Services include high resolution optical sectioning of fixed cells and tissues, time lapse imaging of living cell cultures, non invasive monitoring of tumor formation in preclinical studies, and extracting specific cells of interest from tissue samples.
Proper citation: University of Hawaii at Manoa Microscopy, Imaging, and Flow Cytometry Core Facility (RRID:SCR_021753) Copy
https://med.nyu.edu/research/scientific-cores-shared-resources/ion-laboratory
Electrophysiology core facility that is part of Ion Channels and Transporters in Immunity Research Program.Research area includes ion channel and transporter function and ionic signaling in immune cells.Users who are studying other cell types or organ systems are welcome.Provides assistance with experimental design, training, implementation, and data analysis.
Proper citation: New York University School of Medicine IonLab Core Facility (RRID:SCR_021754) Copy
https://www.uvm.edu/research/imf
Core specializes in design and development of prototypes to advance research. Design engineers complete product development in Solidworks and testing in Labview. Machine shop exists to turn variety of materials into functional prototypes.
Proper citation: University of Vermont Innovate Model Fabricate Labs Core Facility (RRID:SCR_021355) Copy
https://www.centreforbrainhealth.ca/biobank
Centralized resource for collection, storage, and distribution of pre and post mortem biospecimen and tissue at Djavad Mowafaghian Centre for Brain Health.Biobank facility also provides vast range of specimen processing and storage services to other research groups.
Proper citation: University of British Columbia Borgland Brain DNA and Tissue Bank Core Facility (RRID:SCR_021356) Copy
Core laboratory in Room 1043 in Haworth Hall at the University of Kansas Lawrence campus.Provides life and physical sciences and engineering users with wide spectrum of sample preparation tools and techniques and imaging technologies.Provides training for undergraduate, graduate students, postdoctoral researchers, faculty, staff, and industry collaborators.
Proper citation: University of Kansas Microscopy and Analytical Imaging Research Resource Core Facility (RRID:SCR_021801) Copy
https://research.utk.edu/oried/core-facilities/bsmmsc/
Mass Spectrometry Core provides metabolomics, lipidomics, and small molecule analyses to researchers both on campus and in our affiliated local and other institutions.
Proper citation: University of Tennessee Knoxville Biological and Small Molecule Mass Spectrometry Core Facility (RRID:SCR_021368) Copy
https://research.utexas.edu/cbrs/cores/transgenics/
Provides services to generate, cryopreserve, and recover transgenic mice for modeling human disease.MGEF is fully equipped to make genetically engineered mice and is staffed with skilled personnel with decades of transgenic experience.Generates transgenic mice for studying mammalian gene function and modeling human disease, cryopreserves and archives transgenic mouse lines.
Proper citation: University of Texas at Austin Mouse Genetic Engineering Core Facility (RRID:SCR_021927) Copy
https://www.cores.emory.edu/rbc/
One of the Emory Integrated Core Facilities (EICF), is supported by Emory University School of Medicine and the Georgia Clinical and Translational Science Alliance. We plan, execute, and analyze behavioral experiments examining activity, arousal, coordinated movement, learning and memory, anxiety, depression, seizure susceptibility, reward/reinforcement, and aggression in mice and rats.
Proper citation: Emory University Rodent Behavioral Core (RRID:SCR_012499) Copy
https://www.unmc.edu/vcr/cores/vcr-cores/mspcf/index.html
MSPCF maintains and uses equipment for protein separation and imaging, as well as for sample preparation for mass spectrometry analysis. Offers range of bioinformatics tools for data mining and evaluation. Services include Protein Identification, Protein Interactome Analysis, Protein Post-translational Modifications, Quantitative Mass Spectrometry, Molecular Weight determination.
Proper citation: University of Nebraska Medical Center Mass Spectrometry and Proteomics Core Facility (RRID:SCR_012539) Copy
https://www.sbpdiscovery.org/biomedical-research/shared-resources/cancer-metabolism
Facility that aims to investigate role of metabolism in cancer on cellular and organismal level, combining in vitro and in vivo analysis. Comprehensive metabolic facility, including stable isotope tracing and flux analysis. Provides analysis of metabolism using specialist instruments and methodologies, together with advice on planning experiments and analyzing data. All instruments and approaches are available on fee-for-service basis to Cancer Center scientists, but alsoto outside users. Samples for most services can be shipped, but Seahorse analyzer users need to be local so they can bring live cells for analysis.
Proper citation: Sanford Burnham Prebys Medical Discovery Institute Cancer Metabolism Core Facility (RRID:SCR_014873) Copy
http://www.scripps.edu/florida/technologies/cbs/index.html
Core facility that provides access to genome-wide collections of cDNAs and siRNAs that can be used to interrogate cellular models of signal transduction pathways and phenotypes. Services include cell lines, hit-picking clones and various screening sets, and access to equipment.Provides instruments:Analyst Molecular Devices,Embla Molecular Devices, Envision Perkin Elmer, Platemate Matrix, Tecan M200, Wellmate Matrix.
Proper citation: Scripps Research Institute Florida Cell Based High Throughput Screening Core Facility (RRID:SCR_014877) Copy
https://sbpdiscovery.org/research/shared-resources/flow-cytometry/
Facility that provides access to high-speed cell sorting and analytical flow cytometry. Core allows investigators to have 24-hr/day access to variety of analytical flow cytometers available for independent use. Core staff provide technical expertise and hardware and software training, operate the facility cell sorters, and are available to assist with analysis experiments for those who prefer to have their samples run by an expert cytometrist.
Proper citation: Sanford Burnham Prebys Medical Discovery Institute Flow Cytometry Core Facility (RRID:SCR_014854) Copy
https://cbc.arizona.edu/research/support-services/facilities/nuclear-magnetic-resonance-nmr
Interdisciplinary NMR spectroscopy research facility for structural elucidation and study of conformation and dynamics of organic compounds, peptides, oligonucleotides and other small biopolymers.
Proper citation: University of Arizona Nuclear Magnetic Resonance Core Facility (RRID:SCR_012716) Copy
http://www.uab.edu/shp/drc/animal-physiology-core-links
Core that provides diabetes researches with diabetes related phenotyping in small animal models. Their services offered include the assessment of body composition, energy balance, glucose homeostasis, cardiovascular assessment, imaging, and transgenic animals models.
Proper citation: University of Alabama at Birmingham Diabetes Research Center Animal Physiology Core Facility (RRID:SCR_015110) Copy
https://www.ohsu.edu/transgenic-mouse-models-core
Core assists investigators with developing genetically engineered rodent models of human diseases for studying mutant genes and investigating molecular mechanisms underlying pathological processes.
Proper citation: OHSU Transgenic Mouse Models Core Facility (RRID:SCR_009994) Copy
Core offers services for genomic next-generation sequencing library preparation, sequencing and analysis applications including RNAseq, ChIPseq, ATACseq, CRISPR screening, whole genome methylation profiling, targeted resequencing, single-cell RNAseq, exome sequencing, and more. Performs bioinformatics analysis such as integration of multi-omics datasets or specialized analyses. Genomics core technology platforms include Illumina NovaSeq6000, NextSeq500s, MiSeqs, MiniSeq. High throughput sample preparation is performed on Beckman Coulter Biomek FX and i7 systems. Low throughput samples are prepared by technical staff.
Proper citation: Dana-Farber Cancer Institute Molecular Biology Core Facility (RRID:SCR_009754) Copy
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