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https://research.med.psu.edu/core-facilities/metabolic-phenotyping/

Supports research that requires comprehensive assessment of energy balance and body composition in experimental rodents by providing necessary equipment and expertise. Services include training in the use of equipment, consultation on experiment design, and help with data analysis. Instrumentation includes Bruker TD-NMR LF100 Minispec and TSE Phenomaster System with Integrated Stellar Telemetry.

Proper citation: Penn State College of Medicine Metabolic Phenotyping Core Facility (RRID:SCR_022565) Copy   

•   Source: SciCrunch Registry

https://www.purdue.edu/discoverypark/bioscience/facilities/core/metabolite/index.php

Provides technologies that enable both qualitative (defining all components of metabolome) and quantitative (determining differential concentrations of metabolites) metabolomics in complex biological systems.Provides sensitive mass spectrometry coupled with liquid chromatography and gas chromatography for precise sample analysis. Empowers researchers with new technologies, methods development, sample analysis, expert training, and consultation.

Proper citation: Purdue University West Lafayette Metabolite Profiling Core Facility (RRID:SCR_022728) Copy   

•   Source: SciCrunch Registry

https://bioimaging.dbi.udel.edu/flow-cytometry-core-2/

Facility, located at the University of Delaware Main campus (UD) in Newark, Delaware, provides flow cytometry and hematology services. Facility is equipped with 15-color FACSAria Fusion high-speed cell sorters,BD Rhapsody Express Cell Processing Unit,VetScan HM5c veterinary hematology analyzer, Nexcelom Cellometer Vision cell counter, Zeiss Axiovert 200 inverted fluorescent microscope,Thermo Shandon Cytospin 4 & a Beckman Spinchron DLX centrifuge,General Laboratory facilities for Mammalian Cell Culture and Sample preparation,Laminar flow BSL-2 biosafety cabinets, microscopes and centrifuges.

Proper citation: University of Delaware Flow Cytometry Core Facility (RRID:SCR_022861) Copy   

•   Source: SciCrunch Registry

https://www.museumfuernaturkunde.berlin/en/science/micro-ct-laboratory

Provides analysis of biological, palaeontological and geological objects using computer assisted methods. Center for research at museum and for digitisation of scientific collections. Open to external users. In addition to various devices for three dimensional scanning, laboratory has workstations for processing and analysing raw data using 3D volume processing software.

Proper citation: MfN Berlin Micro-CT Laboratory Core Facility (RRID:SCR_022585) Copy   

•   Source: SciCrunch Registry

https://www.fredhutch.org/en/research/shared-resources/core-facilities/hutch-data-core.html

Helps investigators integrate, interpret and explore large and diverse datasets. Provides services that support analysis of large scale datasets for biomedical researchers, drawing on expertise in computational biology, software engineering and cloud architecture. Offers project based scientific analysis by bioinformaticians, automation of analytical pipelines using workflow management platforms, publication of complex datasets with web accelerated graphics, training and documentation to enable scientist driven computation.

Proper citation: Fred Hutchinson Cancer Center Hutch Data Core Facility (RRID:SCR_022614) Copy   

•   Source: SciCrunch Registry

https://www.fredhutch.org/en/research/shared-resources/core-facilities/specimen-processing-research-cell-bank.html

Provides biospecimen sample processing, extraction and biorepository services. Offers expertise to advance preclinical and clinical studies.

Proper citation: Fred Hutchinson Cancer Center Specimen Processing and Research Cell Bank Core Facility (RRID:SCR_022619) Copy   

•   Source: SciCrunch Registry

https://medschool.cuanschutz.edu/rheumatology/research/research-services/gnotobiotic-core-service-center

Provides germ free and gnotobiotic mice, space in which investigators can complete their own studies or hire core to complete experimental manipulations.Facility includes 12 large soft sided vinyl isolators for breeding and 8 small soft sided vinyl isolators for experiments. There is option between using Allentown positive pressure racks and static cage for experimental use.

Proper citation: University of Colorado Anschutz Medical Campus Gnotobiotic Core Facility (RRID:SCR_023245) Copy   

•   Source: SciCrunch Registry

https://research.med.psu.edu/core-facilities/biomolecular-nmr/

Provides services for multiple modern NMR applications, including structure elucidation of small molecules, triple resonance experiments of biomolecules, fragment-based drug discovery, metabolomic and tissue analyses.

Proper citation: Penn State College of Medicine Biomolecular NMR Core Facility (RRID:SCR_023244) Copy   

•   Source: SciCrunch Registry

https://voices.uchicago.edu/psdetsg/

ETSG serves University of Chicago faculty led research projects. ETSG staff is available to help plan, design, build, test, and install mechanical and electro mechanical apparatus.

Proper citation: University of Chicago Engineering and Technical Support Group Core Facility (RRID:SCR_022944) Copy   

•   Source: SciCrunch Registry

https://www.biotech.cornell.edu/core-facilities-brc/facilities/biomolecular-interactions-properties

Provides investigators with access to advanced tools for measuring biomolecular interactions and properties through variety of techniques from high throughput screening via automation to single reaction cuvette based methods.Facility complements technologies and techniques available through our Imaging facility and Proteomics and Metabolomics facility.

Proper citation: Cornell University Biotechnology Resource Center Biomolecular Interactions and Properties Core Facility (RRID:SCR_023117) Copy   

•   Source: SciCrunch Registry

https://chemh.stanford.edu/research/knowledge-centers

Shared resource to provide instrumentation and scientific expertise to Stanford researchers.Each Knowledge Center is organized around specific scientific area and offers services to the research community. Services, advice, training and instrument access, include area in High-Throughput Screening, Medicinal Chemistry, Crystallography, Cryo-EM, Metabolomics, Protein engineering, Protein expression.

Proper citation: Stanford Sarafan Chemistry, Engineering and Medicine for Human Health Knowledge Centers Core Facility (RRID:SCR_023238) Copy   

•   Source: SciCrunch Registry

http://www.nextgen.pitt.edu

Sequencing Core offers Illumina next generation sequencing services to University of Pittsburgh research community. Offers expertise in next generation sequencing technologies. Encourages to contact Assistant Director to arrange for consultation.Staff is available to share their experience and expertise to assist with development of projects of all sizes, standard or custom assay design, and other specialized application needs.

Proper citation: University of Pittsburgh Medical Center Children Hospital of Pittsburgh Health Sciences Sequencing Core Facility (RRID:SCR_023116) Copy   

•   Source: SciCrunch Registry

https://chemh.stanford.edu/research/knowledge-centers/protein-engineering

MSKC is main gateway for Stanford faculty and students interested to study biological molecules using SLAC X-ray facilities and other major bioimaging facilities.

Proper citation: Stanford Sarafan Protein Engineering Knowledge Center Core Facility (RRID:SCR_023237) Copy   

•   Source: SciCrunch Registry

https://chemh.stanford.edu/research/knowledge-centers/metabolomics

Provides scientific expertise and instrumentation for measurement of small molecules such as metabolites and lipids to ChEM-H and Stanford communities. Leverages expertise in mass spectrometry and allied techniques to understand biology of small molecules both metabolites and xenobiotics and to apply that understanding to advances in human health.

Proper citation: Stanford Sarafan Metabolomics Knowledge Center Core Facility (RRID:SCR_023236) Copy   

•   Source: SciCrunch Registry

http://www.arpege.cnrs.frCore FacilityArpege

Offers functional and structural analysis of protein complexes.Offers possibility to characterize all types of molecular interactions: ligand-target binding, protein-protein interactions, signal transduction, and signalling complexes. Staff members are skilled specialists in luminescence-based techniques and in receptor biology.Application portfolio includes Analysis of cell signalling, by measuring signal transduction;Ligand-target binding (pharmacological analysis, affinity, selectivity); Protein-protein interactions (oligomerization, effectors...); Activation of signalling pathways (G proteins, GRK, arrestins & internalization); Intracellular production of second messengers (cAMP, IP1, Ca2+); Phosphorylation of signalling proteins (ERK, AKT...); Measurement of global cell functions and of different cell parameters (proliferation, migration, invasion...).

Proper citation: Arpege Core Facility (RRID:SCR_023092) Copy   

•   Source: SciCrunch Registry

http://www.mgx.cnrs.fr

Offers genomic technologies to academic laboratories and biotechnology companies.Application portfolio includes Whole genome (re)sequencing, including the identification of variants (SNVs, mutations, indels, CNVs);Targeted sequencing, for instance exomes; Transcriptome analyses (RNA-Seq, small RNA-Seq, microarrays), including in single cells (single-cell 3 RNA-seq); Determination of chromatin structure and dynamics (ChIP-Seq, FAIRE-Seq, Hi-C); Epigenetic analyses (ChIP-Seq, RRBS, Bisulphite-Seq);Genotyping (RAD-Seq, GBS, microarrays).

Proper citation: Montpellier GenomiX Core Facility (RRID:SCR_023091) Copy   

•   Source: SciCrunch Registry

https://www.rockefeller.edu/crispr/

Provides gene targeting and mouse embryonic stem cell technology for members of Rockefeller University, Memorial Sloan-Kettering Cancer Center and their collaborators.CRISPR and Genome Editing services include mouse genomic knock-out and knock-in, mouse conditional knock-out, establishing new ES lines for gene targeting services, establishing ES lines from mutant mouse embryos, preparing ES cells introduced from off campus resources for injection or other application, assisting in embryoid body culture and in vitro differentiation of ES cells, and purification and evaluation of DNA for pronuclear injection.

Proper citation: Rockefeller University CRISPR and Genome Editing Resource Center Core Facility (RRID:SCR_023097) Copy   

•   Source: SciCrunch Registry

https://pnf.uchicago.edu

Facility is ISO Class 5 cleanroom that specializes in advanced lithographic processing of hard and soft materials. Facility is focused on supporting basic science, applied research, research and development, and prototype production using micro and nanofabrication.

Proper citation: University of Chicago Pritzker Nanofabrication Core Facility (RRID:SCR_022955) Copy   

•   Source: SciCrunch Registry

https://research.med.psu.edu/core-facilities/hpc/

Provides computational and storage tools needed to efficiently and effectively process data. High performance computing cluster housing compute cores, graphical processing unit cores, and directly attached high speed storage.

Proper citation: Penn State College of Medicine High Performance Computing Core Facility (RRID:SCR_022953) Copy   

•   Source: SciCrunch Registry

https://research.utexas.edu/cbrs/cores/cem/

Offers training, assisted and unassisted use of microscopes and equipment, as well as consultations and collaborations. Support includes single particle cryo-EM, Cryo-ET, Micro-ED,simple characterization of samples in vitrified aqueous mixtures (e.g. nanoparticle size, etc.).

Proper citation: University of Texas at Austin Cryo Electron Microscopy Core Facility (RRID:SCR_022951) Copy   

•   Source: SciCrunch Registry