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SciCrunch Registry is a curated repository of scientific resources, with a focus on biomedical resources, including tools, databases, and core facilities - visit SciCrunch to register your resource.
Core provides services including high throughput next generation sequencing (NGS) to support whole genome, whole exome, RNA-Seq, single cell RNA-Seq, microbiome and global chromatin and methylation studies, biostatistical and bioinformatic support for NGS projects, access to DNA/RNA sequence analysis software, automated Sanger DNA sequencing, genotyping and RNA/DNA quality assessment, access to shared instrumentation such as plate readers, real time thermal cyclers, Agilent Bioanalyzers, fluorimeters, and spectrophotometers.
Proper citation: Marshall University School of Medicine Genomics Core Facility (RRID:SCR_018885) Copy
https://med.virginia.edu/gatc/
Core offers instrumentation and expertise in all areas of bulk and single cell NGS genomics and transcriptomics, as well as training to access core shared instrumentations. Services include RNA Seq, CHIP Seq, ATAC Seq, Amplicon DNA Seq, 16S ribosomal gene sequencing, shot gun sequencing for small genomes and whole exome sequencing.10X Genomics resources include single cell CNV, VDJ, and 3 or 5 RNA seq as well as linked reads.Core provides real time and droplet digital PCR services most suitable for targeted gene expression, SNP genotyping and CNV discovery.
Proper citation: Virginia University School of Medicine Genome Analysis and Technology Core Facility (RRID:SCR_018883) Copy
https://medicine.uky.edu/centers/cobre/genetic-technologies-core
Core provides services related to manipulation and delivery of nucleic acids to biological systems. Services include Production and titering of recombinant viral vectors,including Lentiviruses, Adenoviruses, and Adeno associated viruses;Subcloning;Tagging of open reading frames;Development of plasmids and/or RNAs for CRISPR/Cas manipulation;piggyBac transposon delivery systems;Real-time PCR analysis;Recombineering;In vitro transcription; Core maintains stock of plasmids that provide components for building constructs envisioned by investigator and provides consultative services.Provides training opportunities in the technologies described above, either as a for-credit, one semester class or on a project-related, fee-based basis.
Proper citation: University of Kentucky College of Medicine Genetic Technologies Core Facility (RRID:SCR_021285) Copy
http://www.rockefeller.edu/ddrc/
Core guides researchers in drug discovery by improving efficiency of their bioassays, identifying compounds and targets of function, and in utilizing technologies for measurement of drug/receptor interactions.Center also has spectroscopic and calorimetric equipment for use in studies of interactions of drugs with their targets.
Proper citation: Rockefeller University Fisher Drug Discovery Core Facility (RRID:SCR_020985) Copy
https://med.nyu.edu/research/scientific-cores-shared-resources/cryo-electron-microscopy-laboratory/
Shared resource hosting advanced cryo–electron microscopes fitted with direct detectors as well as equipment for sample preparation.
Proper citation: New York University School of Medicine Langone Health Cryo-Electron Microscopy Laboratory Core Facility (RRID:SCR_019202) Copy
https://www.colorado.edu/rc/resources/petalibrary
Provides service to support storage, archival, and sharing of research data. Available at subsidized cost to any researcher affiliated with University of Colorado Boulder.
Proper citation: University of Colorado Boulder High Performance Computing PetaLibrary Core Facility (RRID:SCR_019299) Copy
https://medicine.uky.edu/centers/cobre/protein-core
Core provides nanobodies production for research as well as protein production, purification, and macromolecular characterization. Offers training on all instruments and equipment, as well as higher level of assistance when projects warrant.
Proper citation: University of Kentucky College of Medicine Protein Core Facility (RRID:SCR_019172) Copy
https://medschool.cuanschutz.edu/immunology-immunotherapy/phism
Core provides Human Immune System as preclinical in vivo model to study human immune system in experimental tractable animal model e.g. immune response to human tumors that readily grow in HIS-mice. Offers immune expertise, experimental procedures and data analysis of immune based assays, such as flow cytometry.
Proper citation: University of Colorado Anschutz Medical Campus Cancer Center PreClinical Human Immune System Mice Shared Resource Core Facility (RRID:SCR_021990) Copy
https://medschool.cuanschutz.edu/corefacilities/ms-metabolomics
Provides investigators with capabilities to identify, characterize, and quantify biomolecules present in tissues, cells, and biological fluids. Facility houses both Proteomics and Metabolomics Cores, and aims to assist members with solving difficult or previously intractable problems in biomedical research. Methods for biomolecule isolation, separation, quantification, identification and bioinformatics analysis, together with expert guidance in study design, are integrated into expertise offered by the Facility.
Proper citation: University of Colorado Anschutz Medical Campus Cancer Center Mass Spectrometry Shared Resource Core Facility (RRID:SCR_021988) Copy
https://medschool.cuanschutz.edu/immunology-immunotherapy/himsr
Facilitates clinical and translational studies by dissecting immune based mechanisms with diagnostic and therapeutic applications. Offers assays including immunophenotyping and functional characterization, multicolor fluorescence tissue imaging, multiplex cytokine analysis, and cellular assays.Sign in to iLab using University of Colorado credentials.
Proper citation: University of Colorado Anschutz Medical Campus Cancer Center Human Immune Monitoring Shared Resource Core Facility (RRID:SCR_021985) Copy
https://medschool.cuanschutz.edu/colorado-cancer-center/research/shared-resources/cell-technologies
Supports basic and translational research projects in biomedical research. CTSR produces hybridomas/monoclonal antibodies to enhance basic research and preclinal studies and makes recombinant proteins for mechanistic and structural studies on proteins.Provides multiple platforms and analytic modules for real time live-cell imaging of cultured cells and organoids to enhance analysis of cancer cell biology. In addition, we maintain a collection of authenticated human cell lines for use in biomedical research. Sign in to iLab using University of Colorado credentials.
Proper citation: University of Colorado Anschutz Medical Campus Cancer Center Cell Technologies Shared Resource Core Facility (RRID:SCR_021982) Copy
https://medschool.cuanschutz.edu/bioinformaticssr
Cancer focused bioinformatics group that assists in all needs related to omics and big data. We assist our collaborators with experimental design, data processing, interpretation, generating publication-quality figures, and preparing manuscripts and grants.
Proper citation: University of Colorado Anschutz Medical Campus Cancer Center Bioinformatics Core Facility (RRID:SCR_021983) Copy
https://opticalimagingcore.vai.org/
Core helps investigators tackle wide range of research questions, from gene expression to cell motility, and is committed to providing training in microscopy best practices. Service requests are placed through CrossLab Solutions.
Proper citation: Van Andel Institute Optical Imaging Core Facility (RRID:SCR_021968) Copy
https://www.research.colostate.edu/arc/
Core is comprised of Materials and Molecular Analysis (MMA), Imaging and Surface Science (ISS), and Bioanalysis and Omics (BIO) centers. MMA provides instrument capabilities and expertise in spectroscopic (optical, NMR, EPR), mass spectrometry, X-ray and materials (magnetic, thermal, physical) characterization of synthetic, environmental and biological materials, both at bulk and molecular scales; BIO provides analysis of complex biological samples using modern mass spectrometry based metabolomics and proteomics approaches, including supporting cheminformatics; ISS provides analysis of complex biological and inorganic samples using near and far field imaging methods, spectroscopy, and other surface analyses.
Proper citation: Colorado State University Analytical Resources Core Facility (RRID:SCR_021758) Copy
https://research.utk.edu/oried/core-facilities/bsmmsc/
Mass Spectrometry Core provides metabolomics, lipidomics, and small molecule analyses to researchers both on campus and in our affiliated local and other institutions.
Proper citation: University of Tennessee Knoxville Biological and Small Molecule Mass Spectrometry Core Facility (RRID:SCR_021368) Copy
https://www.cores.emory.edu/rbc/
One of the Emory Integrated Core Facilities (EICF), is supported by Emory University School of Medicine and the Georgia Clinical and Translational Science Alliance. We plan, execute, and analyze behavioral experiments examining activity, arousal, coordinated movement, learning and memory, anxiety, depression, seizure susceptibility, reward/reinforcement, and aggression in mice and rats.
Proper citation: Emory University Rodent Behavioral Core (RRID:SCR_012499) Copy
https://www.unmc.edu/vcr/cores/vcr-cores/mspcf/index.html
MSPCF maintains and uses equipment for protein separation and imaging, as well as for sample preparation for mass spectrometry analysis. Offers range of bioinformatics tools for data mining and evaluation. Services include Protein Identification, Protein Interactome Analysis, Protein Post-translational Modifications, Quantitative Mass Spectrometry, Molecular Weight determination.
Proper citation: University of Nebraska Medical Center Mass Spectrometry and Proteomics Core Facility (RRID:SCR_012539) Copy
https://www.sbpdiscovery.org/biomedical-research/shared-resources/cancer-metabolism
Facility that aims to investigate role of metabolism in cancer on cellular and organismal level, combining in vitro and in vivo analysis. Comprehensive metabolic facility, including stable isotope tracing and flux analysis. Provides analysis of metabolism using specialist instruments and methodologies, together with advice on planning experiments and analyzing data. All instruments and approaches are available on fee-for-service basis to Cancer Center scientists, but alsoto outside users. Samples for most services can be shipped, but Seahorse analyzer users need to be local so they can bring live cells for analysis.
Proper citation: Sanford Burnham Prebys Medical Discovery Institute Cancer Metabolism Core Facility (RRID:SCR_014873) Copy
http://www.scripps.edu/florida/technologies/cbs/index.html
Core facility that provides access to genome-wide collections of cDNAs and siRNAs that can be used to interrogate cellular models of signal transduction pathways and phenotypes. Services include cell lines, hit-picking clones and various screening sets, and access to equipment.Provides instruments:Analyst Molecular Devices,Embla Molecular Devices, Envision Perkin Elmer, Platemate Matrix, Tecan M200, Wellmate Matrix.
Proper citation: Scripps Research Institute Florida Cell Based High Throughput Screening Core Facility (RRID:SCR_014877) Copy
https://cbc.arizona.edu/research/support-services/facilities/nuclear-magnetic-resonance-nmr
Interdisciplinary NMR spectroscopy research facility for structural elucidation and study of conformation and dynamics of organic compounds, peptides, oligonucleotides and other small biopolymers.
Proper citation: University of Arizona Nuclear Magnetic Resonance Core Facility (RRID:SCR_012716) Copy
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