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https://pmlivingbiobank.uhnresearch.ca/
Core provides services for the use of patient-Derived tumor Organoid (PDO) model.Organoid models are derived from patient-derived xenograft tissues, primary tumors, and metastatic patient tissues. PMLB organoid repository includes models generated from colorectal, pancreatic, and lung cancer tissues.
Proper citation: University Health Network Princess Margaret Living Biobank PDO Core Facility (RRID:SCR_027530) Copy
Core provides services including Basic High-Throughput Sequencing Analysis, Advanced Data Analysis, High Performance Computing.
Proper citation: University Health Network Bioinformatics and High Performance Computing HPC Core Facility (RRID:SCR_027532) Copy
Core provides centralized service for generating AAV particles for cardiovascular studies. The CCDS Virus Production Core offers the production of either pre-made (ex. AAV8-GFP, AAV8 mPCSK9 D377Y) or custom AAVs.
Proper citation: Louisiana State University in Shreveport Center for Cardiovascular Diseases and Sciences (CCDS) Virus Production Core Facility (RRID:SCR_027498) Copy
Offers services to support studies in medical fields across oncology, cardiology, metabolic diseases, radiotheranostics and more.Helps with study design to final data analysis, including GLP-compliant histopathology services.
Proper citation: University Health Network Spatio-Temporal Targeting and Amplification of Radiation Response Core Facility (RRID:SCR_027531) Copy
Core offers services in optical microscopy experiments including: confocal, multiphoton, super-resolution, FRAP, FRET, live-cell timelapse, whole-slide scanning, image analysis and more.
Proper citation: University Health Network Advanced Optical Microscopy Core Facility (RRID:SCR_027535) Copy
https://www.med.uvm.edu/bsr/home
Core offers bioinformatics and data modeling services. Focuses on support for reproducible, well documented, containerized, nextflow pipelines customized to address the specific research questions and biological systems of the investigators. Offers support from preprocessing -omics data, through data integration and manuscript support, based on grant support or a fee-for-service mechanism. Provides training for students and PIs in the form of individual help, seminars, and workshops.
Proper citation: University of Vermont Bioinformatics Shared Resource Core Facility (RRID:SCR_027493) Copy
https://kdtflow.uhnresearch.ca/
Core offers cell sorting and flow cytometry services. Provided instruments include BD FACS Canto II, Beckman Cytoflex LX, BD FACS ARIA III, AutoMacs Cell Separator.
Proper citation: University Health Network Krembil Discovery Tower Flow Cytometry Core Facility (RRID:SCR_027529) Copy
https://www.lerner.ccf.org/cores/light-microscopy/
Core services include: basic light microscopy (determine appropriate staining protocols and offer training and/or assistance in acquiring transmitted and fluorescent digital images with wide-field microscopes); optical sectioning (training and assistance in the use of confocal and multi-photon microscopes); whole slide scanning (brightfield or fluorescence mode). Laser MicroDissection instruments are available for isolating small areas of tissue or single cells. Total Interference Reflection Fluorescence (TIRF) microscopy is available for visualizing and quantifying cellular events localized at the basal plasma membrane. Live cell and tissue imaging can be done on both wide-field and confocal microscopes equipped with environmental chambers for heat/CO2 control.Investigators have access to Image Processing and Analysis workstations with variety of advanced software for extracting quantitative data from their images. They can also generate images and movies for presentations, grants and publications. Core is home to 2 LI-COR Odyssey, laser-based scanning systems for gels, Westerns, in-cell Westerns, ELISA/FLISA, EMSA/Gel Shift, Protein Detection, etc.
Proper citation: Cleveland Clinic Lerner Research Institute Light Microscopy Core Facility (RRID:SCR_027477) Copy
https://www.houstonmethodist.org/academic-institute/research/cores/
Core is fee-for-service research laboratory providing internal and external users a wide spectrum of electron microscopy (EM) techniques. As part of the Houston Methodist Research Institute Department of Neurology, we routinely process samples related to the peripheral nervous system but can help with the ultrastructural study of many biological samples.
Proper citation: Houston Methodist HMRI Neurology Electron Microscopy Core Facility (RRID:SCR_027479) Copy
https://rcgd.isr.umich.edu/research/facilities/zajonc-lab/
Core provides researchers with facilities to conduct experimental research, particularly within the Research Center for Group Dynamics (RCGD) and across the U-M campus. The labs offer adaptable room configurations, specialized software like E-Prime and z-Tree, and shared access to cutting-edge technology, including a new Virtual Reality (VR) Lab, to support a range of interdisciplinary research projects focused on human social behavior and dynamics.
Proper citation: University of Michigan Robert B. Zajonc Experimental Lab Core Facility (RRID:SCR_027478) Copy
https://chem.vt.edu/analyticalservices/surface-analysis-lab.html
Core offers contemporary surface analysis techniques, featuring the latest PHI VersaProbe III Scanning XPS Microscope, and expertise.
Proper citation: Virginia Tech VT Surface Analysis Laboratory Core Facility (RRID:SCR_027504) Copy
https://www.bwhneurosciences.org/neurotechnology-studio/
Offers advanced instrumentation and expert support to advance understanding of brain function and brain disease by providing researchers with access to cutting-edge technologies. Provides access to advanced instrumentation for optical microscopy, genomics, metabolic imaging and other technologies, as well as image analysis software. Provides expert support and training, data quality and interpretation.
Proper citation: Brigham and Women’s Hospital NeuroTechnology Studio Core Facility (RRID:SCR_027687) Copy
Portuguese national research infrastructure which provides expert consultation for the safe and effective use of vector technologies, and offers custom design and production services for multiple viral types to the national research community and other stakeholders.
Proper citation: University of Coimbra ViralVector Core Facility (RRID:SCR_027689) Copy
https://www.augusta.edu/it/hpcs/
Core provides high memory parallel processing environments and software in support of the university research, academic, and cybersecurity missions. HPC clusters use multiple computers to process data in parallel, greatly reducing the time to solution for most computational science tasks. They also provide storage to manage very large data sets.
Proper citation: Augusta University High Performance Computing Core Facility (RRID:SCR_027680) Copy
https://www.lsuhs.edu/centers/center-for-post-transcriptional-regulation/research-cores
Metabolomics and Machine Learning Core provides metabolite profiling and stable-isotope tracing, molecular modeling, and machine learning to integrate datasets across transcriptomic, proteomic, and metabolomic analysis.
Proper citation: Louisiana State University Health Sciences Center Shreveport Metabolomics and Machine Learning Core Facility (RRID:SCR_027717) Copy
https://medicine.tulane.edu/microbiology-immunology/flow-cytometry-and-cell-sorting-facility
Tulane University School of Medicine Department of Microbiology/Immunology Flow cytometry and cell sorting shared resource facility. Provides education, training and services, Applications include analysis and sorting of immune subsets and fluorescent-reporter expressing cells, DNA content, multi-plex bead assays and functional assays. Expert assistance with experimental design and data analysis, as well as instrument training, are available at no charge.
Proper citation: Tulane University School of Medicine Flow Cytometry and Cell Sorting Core Facility (RRID:SCR_027605) Copy
https://icahn.mssm.edu/research/resources/deans-cores/flow-cytometry
Situated within the Icahn School of Medicine at Mount Sinai, our CoRE provides all members of the Mount Sinai Health System community with the instrumentation, expertise, and education required to incorporate flow cytometry and cell sorting into any research project.
Proper citation: Icahn School of Medicine at Mount Sinai Flow Cytometry CoRE Core Facility (RRID:SCR_027701) Copy
https://www.augusta.edu/research/core/proteomics.php
Facility for characterization and expression level quantitation of proteins (isolated or in an extract) and small molecules/metabolites by mass spectrometry (MS) and/or chromatography. Services include protein identification, labeled and label-free comparative proteomics by Orbitrap mass spectometry, protein/small molecule quantification using targeted mass spectometry (PRM and SRM/MRM mass spectometry), high throughput protein immune-protein assays (384-well Luminex/ELISA assay), etc.
Proper citation: Augusta University Proteomics and Mass Spectrometry Core Facility (RRID:SCR_027673) Copy
https://www.augusta.edu/research/core/human-mri
Core dedicated to providing cutting-edge magnetic resonance imaging services for human participants. Provides Human 3 Tesla MRI system from Siemens for human research with proper IRB approval and approved MRI protocols.
Proper citation: Augusta University Human MRI Imaging Core Facility (RRID:SCR_027672) Copy
Core provides iPSC cell culture laboratory with access to curated and validated iPSC lines for neurodegeneration research. Provides robotic and fully automated high-content imaging system to perform high-throughput screening on living brain cells (iPSC derived through reprogramming) to understand the mechanisms behind neurodegeneration at the molecular level.
Proper citation: Van Andel Institute MiND iPSC and Screening Platform Core Facility (RRID:SCR_027675) Copy
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